Most cited papers from Dorn Research Institute

Dorn Research Institute

What are the most cited papers from Dorn Research Institute?

The most cited paper from Dorn Research Institute is "A metagenome-wide association study of gut microbiota in type 2 diabetes" (Junjie Qin et al., 2012), with 7,088 citations. Next come "Richness of human gut microbiome correlates with metabolic markers" (4,843) and "Identification and assembly of genomes and genetic elements in complex metagenomic samples without using reference genomes" (1,332).

Published TypeFieldAccessCitations

Showing 50 of 61 papers. Every paper with more than 73 citations is listed.

Most cited papers, sortable by citations and release date
#	Paper
1	A metagenome-wide association study of gut microbiota in type 2 diabetes Junjie Qin et al. · Nature Open access	25 Sep 2012	7,088
2	Richness of human gut microbiome correlates with metabolic markers Emmanuelle Le Chatelier et al. · Nature Open access	27 Aug 2013	4,843
3	Identification and assembly of genomes and genetic elements in complex metagenomic samples without using reference genomes H Bjørn Nielsen et al. · Nature Biotechnology Open access	6 Jul 2014	1,332
4	Hypothalamic CART is a new anorectic peptide regulated by leptin Peter Lommer Kristensen, Martin E. Judge, Lars Thim et al. · Nature	May 1998	1,293
5	EULAR recommendations for the management of antiphospholipid syndrome in adults Maria G. Tektonidou et al. · Annals of the Rheumatic Diseases Open access	15 May 2019	1,254
6	Opposing actions of Arx and Pax4 in endocrine pancreas development Patrick Collombat, Ahmed Mansouri, Jacob Hecksher‐Sørensen et al. · Genes & Development Open access	15 Oct 2003	619
7	Outcomes of Hydroxychloroquine Usage in United States Veterans Hospitalized with COVID-19 Joseph Magagnoli, Siddharth Narendran, Felipe L. Pereira et al. · Med Open access	5 Jun 2020	585
8	Cytotoxicity of Human p I 7 Interleukin-1 for Pancreatic Islets of Langerhans Klaus Bendtzen, Thomas R Mandrup-Poulsen, Jørn Nerup et al. · Science	20 Jun 1986	531
9	Transcription Factor Hepatocyte Nuclear Factor 6 Regulates Pancreatic Endocrine Cell Differentiation and Controls Expression of the Proendocrine Gene ngn3 Patrick Jacquemin, Serge M. Durviaux, Jan Nygaard Jensen et al. · Molecular and Cellular Biology Open access	Jun 2000	327
10	Antibodies to a 64,000 Mr human islet cell antigen precede the clinical onset of insulin-dependent diabetes. Steinunn Bækkeskov, Maria A. Landin, Jørgen Kvist Kristensen et al. · Journal of Clinical Investigation Open access	Mar 1987	318
11	The global diabetes epidemic as a consequence of lifestyle-induced low-grade inflammation Hubert Kolb, Thomas R Mandrup-Poulsen · Diabetologia Open access	4 Nov 2009	295
12	Imiquimod 5% cream for the treatment of actinic keratosis: results from two phase III, randomized, double-blind, parallel group, vehicle-controlled trials Mark Lebwohl, Scott M. Dinehart, David Whiting et al. · Journal of the American Academy of Dermatology	26 Apr 2004	294
13	Embryonic endocrine pancreas and mature β cells acquire α and PP cell phenotypes upon Arx misexpression Patrick Collombat, Jacob Hecksher‐Sørensen, Jens Krull et al. · Journal of Clinical Investigation Open access	2 Apr 2007	252
14	The Calcimimetic AMG 073 as a Potential Treatment for Secondary Hyperparathyroidism of End-Stage Renal Disease L. Darryl Quarles, Donald J. Sherrard, Stephen Adler et al. · Journal of the American Society of Nephrology	Mar 2003	248
15	Blockade of interleukin 1 in type 1 diabetes mellitus Thomas R Mandrup-Poulsen, Linda Pickersgill, Marc Yves Donath · Nature Reviews Endocrinology Review	22 Feb 2010	242
16	Early growth restriction leads to down regulation of protein kinase C zeta and insulin resistance in skeletal muscle Susan Elizabeth Ozanne, GS Olsen, LL Hansen et al. · Journal of Endocrinology Open access	May 2003	233
17	Insulin resistance: interactions between obesity and a common variant of insulin receptor substrate-1 J. O. Clausen, Torben F. Hansen, Christian Bjørbæk et al. · The Lancet Open access	Aug 1995	214
18	Quantitative assay using recombinant human islet glutamic acid decarboxylase (GAD65) shows that 64K autoantibody positivity at onset predicts diabetes type. William Hagopian, Allan Ertmann Karlsen, Anders Gottsäter et al. · Journal of Clinical Investigation Open access	1993	200
19	Separation of tumor cells with dielectrophoresis-based microfluidic chip Mohammed R. AlShareef, Nicholas Metrakos, Eva Juarez Perez et al. · Biomicrofluidics Open access	2013	188
20	Period 2 Mutation Accelerates ApcMin/+ Tumorigenesis Patricia Ann Wood, Xiaoming Yang, Andrew Taber et al. · Molecular Cancer Research Open access	Nov 2008	185
21	A highly sensitive and specific assay for determination of IGF-I bioactivity in human serum Jian-Wen Chen, Thomas Ledet, Hans Ørskov et al. · American Journal of Physiology-Endocrinology and Metabolism	Jun 2003	178
22	Evaluation of Wet Oxidation Pretreatment for Enzymatic Hydrolysis of Softwood Hetti Palonen, Anne Belinda Thomsen, Maija Tenkanen et al. · Applied Biochemistry and Biotechnology	2004	175
23	Harmonic oscillator model of the insulin and IGF1 receptors’ allosteric binding and activation Vladislav V. Kiselyov, Soetkin Versteyhe, Lisbeth Gauguin et al. · Molecular Systems Biology Open access	17 Feb 2009	172
24	Early Start of Hemodialysis May Be Harmful Steven Jay Rosansky, Paul W. Eggers, Kirby L. Jackson et al. · Archives of Internal Medicine	9 Nov 2010	165
25	The insulin receptor: a prototype for dimeric, allosteric membrane receptors? Pierre De Meyts · Trends in Biochemical Sciences Review	19 Jul 2008	163
26	Signal Transduction via the Mitogen-activated Protein Kinase Pathway Induced by Binding of Coagulation Factor VIIa to Tissue Factor Lars Kaergaard Poulsen, Nana Jacobsen, Brit B. Sørensen et al. · Journal of Biological Chemistry Open access	Mar 1998	148
27	Plasmapheresis in the initial treatment of insulin-dependent diabetes mellitus in children. Johnny Ludvigsson, L. G. Heding, Gudrun Liedén et al. · BMJ Open access	15 Jan 1983	145
28	THE CIRCADIAN CLOCK GENEPER1SUPPRESSES CANCER CELL PROLIFERATION AND TUMOR GROWTH AT SPECIFIC TIMES OF DAY Xiaoming Yang, Patricia Ann Wood, Christine M. Ansell et al. · Chronobiology International	Oct 2009	120
29	Vehicle-controlled, double-blind, randomized study of imiquimod 5% cream applied 3 days per week in one or two courses of treatment for actinic keratoses on the head Joseph Lucius Jorizzo, Scott M. Dinehart, Robert T. Matheson et al. · Journal of the American Academy of Dermatology	23 May 2007	118
30	Gene Expression in Skeletal Muscle Biopsies from People with Type 2 Diabetes and Relatives: Differential Regulation of Insulin Signaling Pathways Jane Palsgaard, Charlotte Brøns, Martin Haljeta Friedrichsen et al. · PLoS ONE Open access	10 Aug 2009	116
31	Pancreatic beta cells express two autoantigenic forms of glutamic acid decarboxylase, a 65-kDa hydrophilic form and a 64-kDa amphiphilic form which can be both membrane-bound and soluble. Stephan Christgau, Hanna Schierbeck, Henk‐Jan Aanstoot et al. · Journal of Biological Chemistry Open access	Nov 1991	116
32	PLD2 Complexes with the EGF Receptor and Undergoes Tyrosine Phosphorylation at a Single Site upon Agonist Stimulation Rita Slaaby, Torben Jensen, Harald Severin Hansen et al. · Journal of Biological Chemistry Open access	Dec 1998	115
33	Molecular cloning of a polymorphic DNA endonuclease fragment associates insulin-dependent diabetes mellitus with HLA-DQ. Birgitte Koch Michelsen, Åke Lernmark · Journal of Clinical Investigation Open access	Apr 1987	114
34	Circadian clock coordinates cancer cell cycle progression, thymidylate synthase, and 5-fluorouracil therapeutic index Patricia Ann Wood, Jovelyn Du‐Quiton, Shaojin You et al. · Molecular Cancer Therapeutics	Aug 2006	110
35	Dielectrophoretic separation of colorectal cancer cells Fang Yang, Xiaoming Yang, Hongyuan Jiang et al. · Biomicrofluidics Open access	12 Jan 2010	108
36	Bradykinin B 2 Receptor-Mediated Mitogen-Activated Protein Kinase Activation in COS-7 Cells Requires Dual Signaling via Both Protein Kinase C Pathway and Epidermal Growth Factor Receptor Transactivation Antje Adomeit, Angela Graneß, Steffen Groß et al. · Molecular and Cellular Biology Open access	Aug 1999	106
37	Variants at DGKB/TMEM195, ADRA2A, GLIS3 and C2CD4B loci are associated with reduced glucose-stimulated beta cell function in middle-aged Danish people Trine Welløv Boesgaard, Niels Grarup, Torben Jørgensen et al. · Diabetologia Open access	24 Apr 2010	104
38	Wortmannin inhibits both insulin- and contraction-stimulated glucose uptake and transport in rat skeletal muscle Jørgen F. P. Wojtaszewski, Bo F. Hansen, Birgitte Ursø et al. · Journal of Applied Physiology	Oct 1996	103
39	Autoantibodies in IDDM Primarily Recognize the 65,000-Mr Rather Than 67,000-Mr Isoform of Glutamic Acid Decarboxylase William Hagopian, Birgitte Koch Michelsen, Allan Ertmann Karlsen et al. · Diabetes	Apr 1993	101
40	Alanine Scanning Mutagenesis of a Type 1 Insulin-like Growth Factor Receptor Ligand Binding Site Jonathan Whittaker, Andreas Velsing Groth, Dennis C. Mynarcik et al. · Journal of Biological Chemistry Open access	Nov 2001	97
41	The role of Brn4/Pou3f4 and Pax6 in forming the pancreatic glucagon cell identity R. Scott Heller, Doris A. Stoffers, Aihua Liu et al. · Developmental Biology Open access	23 Jan 2004	93
42	Activation of the Insulin Receptor by Insulin and a Synthetic Peptide Leads to Divergent Metabolic and Mitogenic Signaling and Responses Maja Jensen, Bente Langvad Hansen, Pierre De Meyts et al. · Journal of Biological Chemistry Open access	9 Oct 2007	91
43	Identification of a growth hormone-responsive STAT5-binding element in the rat insulin 1 gene. Elisabeth Douglas Galsgaard, Fabrice Gouilleux, Bernd Groner et al. · Molecular Endocrinology Open access	Jun 1996	90
44	Daily coordination of cancer growth and circadian clock gene expression Shaojin You, Patricia Ann Wood, Yin Xiong et al. · Breast Cancer Research and Treatment	27 Apr 2005	86
45	Identification of determinants that confer ligand specificity on the insulin receptor. Asser Sloth Andersen, Thomas Kjeldsen, Finn C. Wiberg et al. · Journal of Biological Chemistry Open access	Jul 1992	84
46	Treatment decisions for older adults with advanced chronic kidney disease Steven Jay Rosansky, Jane O. Schell, Joseph W. Shega et al. · BMC Nephrology Open access	19 Jun 2017	83
47	Neonatal Tolerization With Glutamic Acid Decarboxylase But Not With Bovine Serum Albumin Delays the Onset of Diabetes in NOD Mice Jacob Sten Petersen, Allan Ertmann Karlsen, Helle Markholst et al. · Diabetes	Dec 1994	81
48	Cyclosporin A as prophylaxis against graft-versus-host disease in 36 patients. A. John Barrett, J.R. Kendra, C. F. Lucas et al. · BMJ Open access	17 Jul 1982	81
49	Three-Dimensional-Engineered Matrix to Study Cancer Stem Cells and Tumorsphere Formation: Effect of Matrix Modulus Xiaoming Yang, Samaneh Kamali Sarvestani, Seyedsina Moeinzadeh et al. · Tissue Engineering Part A Open access	27 Sep 2012	80
50	The effect of neurogenin3 deficiency on pancreatic gene expression in embryonic mice Andreas Petri, Jonas Ahnfelt‐Rønne, Klaus Stensgaard Frederiksen et al. · Journal of Molecular Endocrinology	Oct 2006	80

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.