Most cited papers from Drug Safety Research Unit

Drug Safety Research Unit

What are the most cited papers from Drug Safety Research Unit?

The most cited paper from Drug Safety Research Unit is "Under-Reporting of Adverse Drug Reactions" (Lorna Hazell, Saad Shakir, 2006), with 1,950 citations. Next come "EPOS 2012: European position paper on rhinosinusitis and nasal polyps 2012. A summary for otorhinolaryngologists" (1,197) and "Helicobacter pylori infection induces gastric cancer in Mongolian gerbils" (997).

Published TypeFieldAccessAuthorsCitations

Showing 50 of 59 papers. Every paper with more than 90 citations is listed.

Most cited papers, sortable by citations and release date
#	Paper
1	Under-Reporting of Adverse Drug Reactions Lorna Hazell, Saad Shakir · Drug Safety	2006	1,950
2	EPOS 2012: European position paper on rhinosinusitis and nasal polyps 2012. A summary for otorhinolaryngologists Wytske Johanna Fokkens et al. · Rhinology Journal Open access	Mar 2012	1,197
3	Helicobacter pylori infection induces gastric cancer in Mongolian gerbils Takeshi Watanabe, Mayumi Tada, Hirofumi Nagai et al. · Gastroenterology Open access	Sep 1998	997
4	Preferences of patients for patient centred approach to consultation in primary care: observational study Paul S Little, Hazel Everitt, Ian Williamson et al. · BMJ Open access	24 Feb 2001	777
5	Randomized Trial of Posaconazole and Benznidazole for Chronic Chagas' Disease Israel Molina, Jordi Gómez i Prat, Fernando Salvador et al. · New England Journal of Medicine Open access	14 May 2014	628
6	Quality assessment of observational studies in a drug-safety systematic review, comparison of two tools: the Newcastle–Ottawa Scale and the RTI item bank Andrea V. Margulis, Manel Pladevall, Nuria Riera‐Guàrdia et al. · Clinical Epidemiology ReviewOpen access	Oct 2014	443
7	Diabetes risk score: towards earlier detection of Type 2 diabetes in general practice Simon J. Griffin, Paul S Little, C. Nicholas Hales et al. · Diabetes/Metabolism Research and Reviews	2000	399
8	Pragmatic randomised controlled trial of two prescribing strategies for childhood acute otitis media Paul S Little, Clare Gould, Ian Williamson et al. · BMJ Open access	10 Feb 2001	398
9	Evaluation of patient reporting of adverse drug reactions to the UK ‘Yellow Card Scheme’: literature review, descriptive and qualitative analyses, and questionnaire surveys Anthony John Avery, Claire Anderson, C. R. Bond et al. · Health Technology Assessment Open access	May 2011	343
10	Nintedanib: From Discovery to the Clinic Gerald J. Roth, Rudolf F. Binder, Florian Colbatzky et al. · Journal of Medicinal Chemistry Open access	4 Dec 2014	338
11	Results of European post-marketing surveillance of bosentan in pulmonary hypertension Marc Humbert, Eleanor S Segal, David Gerard Kiely et al. · European Respiratory Journal Open access	15 May 2007	296
12	PF-06463922 is a potent and selective next-generation ROS1/ALK inhibitor capable of blocking crizotinib-resistant ROS1 mutations Helen Y. Zou et al. · Proceedings of the National Academy of Sciences Open access	2 Mar 2015	271
13	Analysis and reporting of adverse events in randomised controlled trials: a review Rachel Phillips, Lorna Hazell, Odile Sauzet et al. · BMJ Open Open access	Feb 2019	239
14	Pregnancy outcome of women exposed to bupropion during pregnancy: A prospective comparative study Brian Chan, Gideon Koren, Ibrahim Fayez et al. · American Journal of Obstetrics and Gynecology	26 Feb 2005	236
15	Management of depression in UK general practice in relation to scores on depression severity questionnaires: analysis of medical record data Tony Kendrick, Christopher F Dowrick, Andrew J. McBride et al. · BMJ Open access	19 Mar 2009	235
16	Antibiotic prescribing for acute respiratory tract infections in primary care: a systematic review and meta-ethnography Sarah KG Tonkin-Crine, Lucy Yardley, Paul S Little · Journal of Antimicrobial Chemotherapy Review	15 Jul 2011	230
17	High-Mobility Group Box-1 Protein and Keratin-18, Circulating Serum Proteins Informative of Acetaminophen-Induced Necrosis and Apoptosis In Vivo Daniel James Antoine, Dominic P. Williams, Anja Kipar et al. · Toxicological Sciences	25 Sep 2009	223
18	Age and sex distribution of suspected adverse drug reactions to newly marketed drugs in general practice in England: analysis of 48 cohort studies Richard Michael Martin, Pipasha N. Biswas, Shayne N. Freemantle et al. · British Journal of Clinical Pharmacology Open access	Nov 1998	223
19	Prenatal Exposure to Acetaminophen and Risk of ADHD Eivind Ystrøm, Kristin Gustavson, Ragnhild Eek Brandlistuen et al. · PEDIATRICS Open access	30 Oct 2017	217
20	Patients' and doctors' views on depression severity questionnaires incentivised in UK quality and outcomes framework: qualitative study Christopher F Dowrick, Geraldine Leydon, Andrew J. McBride et al. · BMJ Open access	19 Mar 2009	215
21	Use of Micropatterned Cocultures to Detect Compounds That Cause Drug-Induced Liver Injury in Humans Salman R. Khetani, Chitra Kanchagar, Okechukwu T. Ukairo et al. · Toxicological Sciences	14 Nov 2012	211
22	Rna Expression in the Early Characterization of Hepatotoxicants in Wistar Rats by High–Density Dna Microarrays Steven J. Bulera, Susan M. Eddy, Erika Ferguson et al. · Hepatology Open access	May 2001	183
23	PF-04691502, a Potent and Selective Oral Inhibitor of PI3K and mTOR Kinases with Antitumor Activity Jing Yuan et al. · Molecular Cancer Therapeutics Open access	13 Jul 2011	163
24	Toxicogenomics of nevirapine-associated cutaneous and hepatic adverse events among populations of African, Asian, and European descent Jing Yuan, Sheng Jie Guo, David B. Hall et al. · AIDS Open access	19 Apr 2011	155
25	Underreporting of suspected adverse drug reactions to newly marketed (“black triangle”) drugs in general practice: observational study Richard Michael Martin, Ketan Kapoor, Lynda V Wilton et al. · BMJ Open access	11 Jul 1998	152
26	Challenges for Drug Repurposing in the COVID-19 Pandemic Era Janet Sultana, Salvatore Crisafulli, Flic Gabbay et al. · Frontiers in Pharmacology Open access	6 Nov 2020	150
27	The outcomes of pregnancy in women exposed to newly marketed drugs in general practice in England Lynda V Wilton, G. L. Pearce, Richard Michael Martin et al. · BJOG An International Journal of Obstetrics & Gynaecology	Aug 1998	150
28	Safety of Long‐Term Lamotrigine in Epilepsy F. J. Mackay, Lynda V Wilton, G. L. Peace et al. · Epilepsia	Aug 1997	147
29	General Practitioners’ Empathy and Health Outcomes: A Prospective Observational Study of Consultations in Areas of High and Low Deprivation Stewart William Mercer, Maria Higgins, A.M. Bikker et al. · The Annals of Family Medicine Open access	Mar 2016	146
30	An investigation into drug products withdrawn from the EU market between 2002 and 2011 for safety reasons and the evidence used to support the decision-making Rhian McNaughton, Gwenaël Huet, Saad Shakir · BMJ Open Open access	2014	143
31	Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height Matthew Bruce Lanktree et al. · The American Journal of Human Genetics ReviewOpen access193 authors	31 Dec 2010	135
32	Randomised controlled trial of Alexander technique lessons, exercise, and massage (ATEAM) for chronic and recurrent back pain: economic evaluation Sandra P Hollinghurst, Debbie Sharp, Kate Ballard et al. · BMJ Open access	11 Dec 2008	135
33	Discriminating Different Classes of Toxicants by Transcript Profiling Guido Steiner, Laura Suter‐Dick, Franziska Boess et al. · Environmental Health Perspectives Open access	Jul 2004	132
34	Cardiovascular events in users of sildenafil: results from first phase of prescription event monitoring in England Saad Shakir, Lynda V Wilton, Andrew Boshier et al. · BMJ Open access	17 Mar 2001	132
35	Characterization of a functional C3A liver spheroid model Harriet Gaskell, Parveen Sharma, Helen Elizabeth Colley et al. · Toxicology Research Open access	2016	131
36	Mitochondrial Regulation of Cell Death: Mitochondria Are Essential for Procaspase 3-p21 Complex Formation To Resist Fas-Mediated Cell Death Atsushi Suzuki, Yumi Tsutomi, Naoe Yamamoto et al. · Molecular and Cellular Biology Open access	May 1999	131
37	Machine Learning for Toxicity Prediction Using Chemical Structures: Pillars for Success in the Real World Srijit Seal et al. · Chemical Research in Toxicology Open access	2 May 2025	128
38	Prescription-event monitoring and reporting of adverse drug reactions Emma L. Heeley, Jane E. Riley, Deborah Layton et al. · The Lancet	Dec 2001	127
39	Common Variation in the NOS1AP Gene Is Associated With Drug-Induced QT Prolongation and Ventricular Arrhythmia Yalda Jamshidi, Ilja Maria Nolte, Chrysoula Dalageorgou et al. · Journal of the American College of Cardiology Open access	6 Jun 2012	121
40	Causal Association in Pharmacovigilance and Pharmacoepidemiology Saad Shakir, Deborah Layton · Drug Safety	2002	121
41	Adverse effects associated with the use of donepezil in general practice in England Norris Ray Dunn, G. L. Pearce, Saad Shakir · Journal of Psychopharmacology	Jul 2000	120
42	Prescription‐event monitoring—recent progress and future horizons Ronald D. Mann · British Journal of Clinical Pharmacology Open access	Sep 1998	114
43	Postmarketing surveillance of enalapril. I: Results of prescription-event monitoring. William H. W. Inman, Nigel S. B. Rawson, Lynda V Wilton et al. · BMJ Open access	Oct 1988	113
44	A comparison of ciprofloxacin, norfloxacin, ofloxacin, azithromycin and cefixime examined by observational cohort studies Lynda V Wilton, G. L. Pearce, Ronald D. Mann · British Journal of Clinical Pharmacology Open access	Apr 1996	113
45	Antidiabetic (type 2) effects of Lactobacillus G15 and Q14 in rats through regulation of intestinal permeability and microbiota Peijun Tian, Bao‐Long Li, Canxia He et al. · Food & Function	2016	112
46	Evaluation of Serum Bile Acid Profiles as Biomarkers of Liver Injury in Rodents Lina Luo, Shelli Schomaker, Christopher D. Houle et al. · Toxicological Sciences	Oct 2013	109
47	Salmeterol: A study by Prescription Event Monitoring in a UK cohort of 15,407 patients Ronald D. Mann, Kiyoshi Kubota, Gillian L. Pearce et al. · Journal of Clinical Epidemiology	Feb 1996	108
48	Narrative review of primary care point-of-care testing (POCT) and antibacterial use in respiratory tract infection (RTI) Jonathan Cooke, Christopher Butler, Rogier Hopstaken et al. · BMJ Open Respiratory Research ReviewOpen access	May 2015	108
49	Adverse Drug Reaction Reporting in the UK David J. McLernon, Christine M Bond, Philip C Hannaford et al. · Drug Safety	12 Aug 2010	107
50	Prevalence of Churg-Strauss syndrome, vasculitis, eosinophilia and associated conditions: retrospective analysis of 58 prescription-event monitoring cohort studies Richard Michael Martin, Lynda V. Wilton, Ronald D. Mann · Pharmacoepidemiology and Drug Safety	May 1999	106

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.