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Institution · Ebara (Japan)

Most cited papers from Ebara (Japan)

What are the most cited papers from Ebara (Japan)?

The most cited paper from Ebara (Japan) is "Encapsulation of Hydrophilic and Lipophilic Drugs in PLGA Nanoparticles by the Nanoprecipitation Method" (José Mário Barichello, Mariko Morishita, Kozo Takayama et al., 1999), with 544 citations. Next come "Biodegradation and distribution of water-soluble chitosan in mice" (488) and "Pyrroloindolone Synthesis via a Cp*CoIII-Catalyzed Redox-Neutral Directed C–H Alkenylation/Annulation Sequence" (463).

Showing 50 of 60 papers. Every paper with more than 143 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Encapsulation of Hydrophilic and Lipophilic Drugs in PLGA Nanoparticles by the Nanoprecipitation Method José Mário Barichello, Mariko Morishita, Kozo Takayama et al. · Drug Development and Industrial Pharmacy 1999 544
2 Biodegradation and distribution of water-soluble chitosan in mice Hiraku Onishi, Yoshiharu Machida · Biomaterials 1999 488
3 Pyrroloindolone Synthesis via a Cp*CoIII-Catalyzed Redox-Neutral Directed C–H Alkenylation/Annulation Sequence Hideya Ikemoto, Tatsuhiko Yoshino, Ken Sakata et al. · Journal of the American Chemical Society 20 Mar 2014 463
4 Antioxidative and Anti-Glycation Activity of Garcinol fromGarcinia indicaFruit Rind Fumio Yamaguchi, Toshiaki Ariga, Yoshihiro Yoshimura et al. · Journal of Agricultural and Food Chemistry 15 Jan 2000 452
5 Current challenges in non-invasive insulin delivery systems: A comparative review El‐Sayed Khafagy, Mariko Morishita, Yoshinori Onuki et al. · Advanced Drug Delivery Reviews Review 23 Aug 2007 436
6 Determination of mRNA Expression of Human UDP-Glucuronosyltransferases and Application for Localization in Various Human Tissues by Real-Time Reverse Transcriptase-Polymerase Chain Reaction Shuji Ohno, Shizuo Nakajin · Drug Metabolism and Disposition 7 Oct 2008 428
7 Epigenetic mechanisms of chronic pain Giannina Descalzi, Daigo Ikegami, Toshikazu Ushijima et al. · Trends in Neurosciences ReviewOpen access 9 Mar 2015 404
8 Characteristics of carbohydrate degradation and the rate‐limiting step in anaerobic digestion Tatsuya Noike, Ginro Endo, Juu‐En Chang et al. · Biotechnology and Bioengineering Oct 1985 361
9 Application of Chitin and Chitosan Derivatives in the Pharmaceutical Field Yoshinori Katō, Hiraku Onishi, Yoshiharu Machida · Current Pharmaceutical Biotechnology Oct 2003 301
10 Dehydrative Direct CH Allylation with Allylic Alcohols under [Cp*CoIII] Catalysis Yudai Suzuki, Bo Sun, Ken Sakata et al. · Angewandte Chemie International Edition Jul 2015 301
11 Impairment of endothelium‐dependent relaxation and changes in levels of cyclic GMP in aorta from streptozotocin‐induced diabetic rats Katsuo Kamata, Noriyuki Miyata, Yutaka Kasuya · British Journal of Pharmacology Open access Jun 1989 291
12 Monitoring impact of in situ biostimulation treatment on groundwater bacterial community by DGGE Tomotada Iwamoto, Katsuji Tani, Kanji Nakamura et al. · FEMS Microbiology Ecology Apr 2000 235
13 Sex difference of cytochrome P-450 in the rat: Purification, characterization, and quantitation of constitutive forms of cytochrome P-450 from liver microsomes of male and female rats Tetsuya Kamataki, Kaori Maeda, Yasushi Yamazoe et al. · Archives of Biochemistry and Biophysics Sep 1983 234
14 Absorption of insulin from Pluronic F-127 gels following subcutaneous administration in rats José Mário Barichello, Mariko Morishita, Kozo Takayama et al. · International Journal of Pharmaceutics Jul 1999 234
15 Determination of bisphenol A in human serum by high-performance liquid chromatography with multi-electrode electrochemical detection Kōichi Inoue, Kayoko Kato, Yoshihiro Yoshimura et al. · Journal of Chromatography B Biomedical Sciences and Applications Nov 2000 221
16 C21 steroid side chain cleavage enzyme from porcine adrenal microsomes. Purification and characterization of the 17 alpha-hydroxylase/C17,20-lyase cytochrome P-450. Shizuo Nakajin, Masato SHINODA, Mitsuru Haniu et al. · Journal of Biological Chemistry Open access Mar 1984 214
17 Novel stir bar sorptive extraction methods for environmental and biomedical analysis Migaku Kawaguchi, Rie Ito, Koichi Saito et al. · Journal of Pharmaceutical and Biomedical Analysis 20 Oct 2005 211
18 Antipruritic activity of the κ-opioid receptor agonist, TRK-820 Yuko Togashi, Hideo Umeuchi, Kiyoshi Okano et al. · European Journal of Pharmacology 2002 208
19 Mechanistic investigation of poly(ethylene imine)-based siRNA delivery: Disulfide bonds boost intracellular release of the cargo Miriam Breunig, Constantin Hozsa, Uta Lungwitz et al. · Journal of Controlled Release 4 Jun 2008 207
20 Enhanced intracellular delivery and improved antitumor efficacy of doxorubicin by sterically stabilized liposomes modified with a synthetic RGD mimetic Xiao-Bing Xiong, Yue Huang, Wan-Liang Lü et al. · Journal of Controlled Release 26 Aug 2005 205
21 Molecular evolution of the ribonuclease superfamily Jaap J. Beintema, Cornelis SCHÜLLER, Masachika IRIE et al. · Progress in Biophysics and Molecular Biology Open access 1988 202
22 Antioxidative Effect of Maillard Reaction Products Using Glucose−Glycine Model System Yoshihiro Yoshimura, Tsutomu Iijima, Takaho Watanabe et al. · Journal of Agricultural and Food Chemistry Oct 1997 201
23 Self-Immobilization of Aerobic Activated Sludge–A Pilot Study of the Aerobic Upflow Sludge Blanket Process in Municipal Sewage Treatment Koji Mishima, Michio NAKAMURA · Water Science & Technology Feb 1991 201
24 Novel oral insulin delivery systems based on complexation polymer hydrogels: Single and multiple administration studies in type 1 and 2 diabetic rats Mariko Morishita, Takahiro Goto, Koji Nakamura et al. · Journal of Controlled Release Open access 3 Dec 2005 191
25 Liposomes as Carriers for Topical and Transdermal Delivery Elka Touítou, Hans E. Junginger, N. Weiner et al. · Journal of Pharmaceutical Sciences Sep 1994 190
26 Regulations of opioid dependence by opioid receptor types Minoru Narita, Masahiko Funada, Tsutomu Suzuki · Pharmacology & Therapeutics 2001 190
27 Down-Regulation of miR-133a Contributes to Up-Regulation of RhoA in Bronchial Smooth Muscle Cells Yoshihiko Chiba, Miki Tanabe, Kumiko Goto et al. · American Journal of Respiratory and Critical Care Medicine 30 Jul 2009 189
28 Free Radical Scavenging Activity and Antiulcer Activity of Garcinol fromGarcinia indicaFruit Rind Fumio Yamaguchi, Makoto Saito, Toshiaki Ariga et al. · Journal of Agricultural and Food Chemistry 19 May 2000 188
29 Circular dichroism calculation for natural products Alfarius Eko Nugroho, Hiroshi Morita · Journal of Natural Medicines Open access 6 Apr 2013 188
30 Vanadium redox reactions and carbon electrodes for vanadium redox flow battery Hiroko Kaneko, Ken Nozaki, Yutaka Wada et al. · Electrochimica Acta 1991 187
31 Hippocampal epigenetic modification at the brain‐derived neurotrophic factor gene induced by an enriched environment Naoko Kuzumaki, Daigo Ikegami, Rie Tamura et al. · Hippocampus Open access 15 Mar 2010 184
32 Usefulness of cell-penetrating peptides to improve intestinal insulin absorption Noriyasu Kamei, Mariko Morishita, Yoshimi Eda et al. · Journal of Controlled Release 7 Aug 2008 177
33 Needs analysis: Planning a syllabus for a series of intensive workplace courses at a leading Japanese company Jeremy David Cowling · English for Specific Purposes 2007 175
34 Oral biodrug delivery using cell-penetrating peptide El‐Sayed Khafagy, Mariko Morishita · Advanced Drug Delivery Reviews Review 5 Jan 2012 173
35 Novel chitosan wound dressing loaded with minocycline for the treatment of severe burn wounds Shuichi Aoyagi, Hiraku Onishi, Yoshiharu Machida · International Journal of Pharmaceutics 19 Sep 2006 173
36 N-succinyl-chitosan as a drug carrier: water-insoluble and water-soluble conjugates Yoshinori Katō, Hiraku Onishi, Yoshiharu Machida · Biomaterials 22 Sep 2003 172
37 Discovery of PACAP and its receptors in the brain Takahiro Hirabayashi, Tomoya Nakamachi, Seiji Shioda · The Journal of Headache and Pain Open access 4 Apr 2018 171
38 Generating high-efficiency neutral beams by using negative ions in an inductively coupled plasma source Seiji Samukawa, Keisuke Sakamoto, Katsunori Ichiki · Journal of Vacuum Science & Technology A Vacuum Surfaces and Films Sep 2002 170
39 Elucidation of the mechanism of incorporation of insulin in controlled release systems based on complexation polymers Mariko Morishita, Anthony M. Lowman, Kozo Takayama et al. · Journal of Controlled Release Open access May 2002 170
40 Blockade of morphine reward through the activation of κ-opioid receptors in mice Masahiko Funada, Tsutomu Suzuki, Minoru Narita et al. · Neuropharmacology Dec 1993 168
41 Health foods and foods with health claims in Japan Hirobumi Ohama, Hideko Ikeda, Hiroyoshi Moriyama · Toxicology 21 Feb 2006 167
42 Three-Dimensional Organized Vortices above Flexible Water Plants Syunsuke IKEDA, Minoru Kanazawa · Journal of Hydraulic Engineering Nov 1996 166
43 A novel approach using functional peptides for efficient intestinal absorption of insulin Mariko Morishita, Noriyasu Kamei, Jumpei Ehara et al. · Journal of Controlled Release 30 Dec 2006 166
44 Implication of brain-derived neurotrophic factor in the release of dopamine and dopamine-related behaviors induced by methamphetamine Minoru Narita, Kazue Aoki, Misa Takagi et al. · Neuroscience 21 Jun 2003 166
45 pH-sensitive nanoparticles for improving the oral bioavailability of cyclosporine A Jun-dong Dai, Tsuneji Nagai, Xueqing Wang et al. · International Journal of Pharmaceutics 7 Jul 2004 160
46 Prolonged hypoglycemic effect of insulin-loaded polybutylcyanoacrylate nanoparticles after pulmonary administration to normal rats Qiang Zhang, Zancong Shen, Tsuneji Nagai · International Journal of Pharmaceutics May 2001 160
47 In vitro and in vivo nasal mucoadhesion of some water-soluble polymers Fumihiko Nakamura · International Journal of Pharmaceutics 28 May 1996 159
48 Free Radical Scavenging Activity of Grape Seed Extract and Antioxidants by Electron Spin Resonance Spectrometry in an H2O2/NaOH/DMSO System Fumio Yamaguchi, Yoshihiro Yoshimura, Hiroyuki Nakazawa et al. · Journal of Agricultural and Food Chemistry 26 Jun 1999 158
49 Determination of bisphenol A in river water and body fluid samples by stir bar sorptive extraction with in situ derivatization and thermal desorption-gas chromatography–mass spectrometry Migaku Kawaguchi, Kōichi Inoue, Mariko Yoshimura et al. · Journal of Chromatography B 28 Feb 2004 152
50 In vivo proof of concept of oral insulin delivery based on a co-administration strategy with the cell-penetrating peptide penetratin Ebbe Juel Bech Nielsen, Shinya Yoshida, Noriyasu Kamei et al. · Journal of Controlled Release 25 Jun 2014 151

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.