Institution · ECI Biotech (United States)

Most cited papers from ECI Biotech (United States)

ECI Biotech (United States)

What are the most cited papers from ECI Biotech (United States)?

The most cited paper from ECI Biotech (United States) is "Separation and characterization of saponins with adjuvant activity from Quillaja saponaria Molina cortex" (Charlotte Read Kensil, Urmila H. Patel, Michael Lennick et al., 1991), with 655 citations. Next come "The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation" (645) and "Saponins as vaccine adjuvants." (296).

Published TypeFieldAccessAuthorsCitations

Showing 50 of 94 papers. Every paper is listed.

Most cited papers, sortable by citations and release date
#	Paper
1	Separation and characterization of saponins with adjuvant activity from Quillaja saponaria Molina cortex Charlotte Read Kensil, Urmila H. Patel, Michael Lennick et al. · The Journal of Immunology	1991	655
2	The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation Brian P. Palenik et al. · Proceedings of the National Academy of Sciences Open access	26 Apr 2007	645
3	Saponins as vaccine adjuvants. Kensil Cr · PubMed	1996	296
4	Saponin adjuvant enhancement of antigen-specific immune responses to an experimental HIV-1 vaccine Jiayan Wu, B H Gardner, Cheryl Isaac Murphy et al. · The Journal of Immunology	Mar 1992	241
5	Saponin adjuvant induction of ovalbumin-specific CD8+ cytotoxic T lymphocyte responses Mark J. Newman, Jiayan Wu, B H Gardner et al. · The Journal of Immunology	Apr 1992	224
6	Phase 1 trial of immunological adjuvant QS-21 with a GM2 ganglioside-keyhole limpet haemocyanin conjugate vaccine in patients with malignant melanoma Philip O. Livingston, Sucharita Adluri, Friedhelm Helling et al. · Vaccine	1994	215
7	Structure/function studies of QS-21 adjuvant: assessment of triterpene aldehyde and glucuronic acid roles in adjuvant function Sean Soltysik, Jiayan Wu, Joanne Recchia et al. · Vaccine	1995	188
8	Helper-cytotoxic T lymphocyte (CTL) determinant linkage required for priming of anti-HIV CD8+ CTL in vivo with peptide vaccine constructs. Mutsunori Shirai, C D Pendleton, J Ahlers et al. · The Journal of Immunology	1994	183
9	Humanized mouse models to study human diseases Michael A. Brehm, Leonard D. Shultz, Dale L. Greiner · Current Opinion in Endocrinology Diabetes and Obesity Open access	Apr 2010	178
10	PROLONGED SURVIVAL OF MOUSE SKIN ALLOGRAFTS IN RECIPIENTS TREATED WITH DONOR SPLENOCYTES AND ANTIBODY TO CD40 LIGAND1 Thomas G. Markees, Nancy E. Phillips, Randolph J. Noelle et al. · Transplantation	Jul 1997	166
11	Structural and Immunological Characterization of the Vaccine Adjuvant QS-21 Charlotte Read Kensil, Jiayan Wu, Sean Soltysik · Pharmaceutical biotechnology Book chapter	1995	140
12	Distinctive genetic and clinical features of CMT4J: a severe neuropathy caused by mutations in the PI(3,5)P2 phosphatase FIG4 Garth A. Nicholson, Guy M. Lenk, Stephen Reddel et al. · Brain Open access	23 Jun 2011	125
13	Structure of the saponin adjuvant QS-21 and its base-catalyzed isomerization product by 1H and natural abundance 13C NMR spectroscopy Neil E. Jacobsen, Wayne J. Fairbrother, Charlotte Read Kensil et al. · Carbohydrate Research	1996	113
14	In Vivo Evidence for Instability of Episomal Human Immunodeficiency Virus Type 1 cDNA Mark E. Sharkey, Karine Triques, Daniel R. Kuritzkes et al. · Journal of Virology Open access	28 Mar 2005	104
15	Tumor necrosis factor-α induces the expression of DR6, a member of the TNF receptor family, through activation of NF-κB Gary M. Kasof, Jian J Lu, Derong Liu et al. · Oncogene	29 Nov 2001	102
16	Isomerization and Formulation Stability of the Vaccine Adjuvant QS-21 Jeffrey L. Cleland, Charlotte Read Kensil, Amy Lim et al. · Journal of Pharmaceutical Sciences	1996	96
17	Biochemical and Genetic Tests for Inhibitors of Leishmania Pteridine Pathways LW Hardy, W. Stephen Matthews, Bakela Nare et al. · PubMed	Nov 1997	94
18	Genetically-engineered subunit vaccine against feline leukaemia virus: protective immune response in cats Dante J. Marciani, Charlotte Read Kensil, Gerald A. Beltz et al. · Vaccine	Feb 1991	93
19	Aptamer-based fluorescence polarization assay for separation-free exosome quantification Zhen Zhang, Chuanhao Tang, Libo Zhao et al. · Nanoscale	2019	89
20	Oncofetal protein IMP3 Zhong Li Jiang, Christine Marie Lohse, Peigou G. Chu et al. · Cancer Open access	15 Apr 2008	85
21	NOD-scid IL2rγnull Mouse Model of Human Skin Transplantation and Allograft Rejection Waldemar J. Racki, Laurence Covassin, Michael A. Brehm et al. · Transplantation Open access	3 Mar 2010	84
22	Phosphoproteomics of collagen receptor networks reveals SHP-2 phosphorylation downstream of wild-type DDR2 and its lung cancer mutants Leo Kei Iwai, Leo S. Payne, Maciej T. Luczynski et al. · Biochemical Journal Open access	5 Jul 2013	76
23	Structure—Function Relationship among Quillaja Saponins Serving as Excipients for Nasal and Ocular Delivery of Insulin Dennis J. Pillion, Jennifer A. Amsden, Charlotte Read Kensil et al. · Journal of Pharmaceutical Sciences	May 1996	66
24	Targeting the chromatin remodeling enzyme BRG1 increases the efficacy of chemotherapy drugs in breast cancer cells Qiong Wu, Soni Sharma, Hang Cui et al. · Oncotarget Open access	25 Mar 2016	65
25	Humanized NOD/LtSz‐scid IL2 Receptor Common Gamma Chain Knockout Mice in Diabetes Research Leonard D. Shultz, Todd Pearson, MARIE KING et al. · Annals of the New York Academy of Sciences	Apr 2007	61
26	Structure/Function Studies on QS-21, A Unique Immunological Adjuvant from Quillaja saponaria Charlotte Read Kensil, Sean Soltysik, Deborah A. Wheeler et al. · Advances in experimental medicine and biology Book chapter	1996	61
27	Economic comparison of calcium fumarate and sodium fumarate production byRhizopus arrhizus Irene C. Gangl, William A. Weigand, Frederick A. Keller · Applied Biochemistry and Biotechnology	Mar 1990	57
28	Concise Review: The High Cost of High Tech Medicine: Planning Ahead for Market Access Dawn Driscoll, Stephanie H. Farnia, Panos Kefalas et al. · Stem Cells Translational Medicine Open access	27 Jul 2017	56
29	HIV-1 did not contribute to the 2019-nCoV genome Chuan Xiao, Xiaojun Li, Shuying Liu et al. · Emerging Microbes & Infections Open access	2020	49
30	Nicotinamide Adenine Dinucleotide Augmentation in Overweight or Obese Middle-Aged and Older Adults: A Physiologic Study Karol Mateusz Pencina et al. · The Journal of Clinical Endocrinology & Metabolism Open access	6 Feb 2023	48
31	Protection of Dogs from Lyme Disease with a Vaccine Containing Outer Surface Protein (Osp) A, OspB, and the Saponin Adjuvant QS21 Richard T. Coughlin, Durland Fish, Thomas N. Mather et al. · The Journal of Infectious Diseases Open access	Apr 1995	46
32	Alterations in urine, serum and brain metabolomic profiles exhibit sexual dimorphism during malaria disease progression Angika Basant, Mayuri Rege, Shobhona Sharma et al. · Malaria Journal Open access	23 Apr 2010	45
33	Enhanced Expression, Secretion, and Large-Scale Purification of Recombinant HIV-1 gp120 in Insect Cells Using the Baculovirus egt and p67 Signal Peptides Cheryl Isaac Murphy, J.R. Mcintire, Dave Davis et al. · Protein Expression and Purification	Oct 1993	45
34	Impact of the saponin adjuvant QS-21 and aluminium hydroxide on the immunogenicity of recombinant OspA and OspB of Borrelia burgdorferi Jianneng Ma, Patrice A. Bulger, Deborah vR. Davis et al. · Vaccine	1994	44
35	Concurrent infection of human macrophages with HIV-1 and Mycobacterium avium results in decreased cell viability, increased M. avium multiplication and altered cytokine production. G W Newman, T G Kelley, Huixuan Gan et al. · The Journal of Immunology	Aug 1993	44
36	Corneal Epithelium Expresses a Variant of P2X7 Receptor in Health and Disease Courtney Mankus, Celeste B. Rich, Martin Minns et al. · PLoS ONE Open access	6 Dec 2011	42
37	Induction of Antigen-Specific Killer T Lymphocyte Responses Using Subunit SIV mac251 gag and env Vaccines Containing QS-21 Saponin Adjuvant Mark J. Newman, Kenneth J. Munroe, Christine A. Anderson et al. · AIDS Research and Human Retroviruses	Jul 1994	42
38	Adjuvant Activity of QS‐21 Isomers Sean Soltysik, Deborah A. Bedore, Charlotte Read Kensil · Annals of the New York Academy of Sciences	Aug 1993	40
39	Molecular analysis of neutralizing epitopes on outer surface proteins A and B of Borrelia burgdorferi Ji Ma, Cindy Gingrich-Baker, Paola Franchi et al. · Infection and Immunity Open access	Jun 1995	39
40	Accessory Cell Requirements for Saponin Adjuvant-Induced Class I MHC Antigen-Restricted Cytotoxic T-Lymphocytes Jiayan Wu, B H Gardner, Nicholas N. Kushner et al. · Cellular Immunology	Apr 1994	38
41	DS-1, a Modified Quillaja Saponin, Enhances Ocular and Nasal Absorption of Insulin Dennis J. Pillion, Joanne Recchia, Ping Wang et al. · Journal of Pharmaceutical Sciences	Nov 1995	36
42	Immunogenicity and Toxicity Testing of an Experimental HIV-1 Vaccine in Nonhuman Primates Mark J. Newman, JIA-YAN WU, Richard T. Coughlin et al. · AIDS Research and Human Retroviruses	Aug 1992	36
43	Regulation of Skin and Islet Allograft Survival in Mice Treated With Costimulation Blockade is Mediated by Different CD4+ Cell Subsets and Different Mechanisms Scott J. Banuelos, Thomas G. Markees, Nancy E. Phillips et al. · Transplantation	7 Sep 2004	35
44	Chemoproteomic Evaluation of Target Engagement by the Cyclin-Dependent Kinase 4 and 6 Inhibitor Palbociclib Correlates with Cancer Cell Response Tyzoon K. Nomanbhoy, Geeta Sharma, Heidi E. Brown et al. · Biochemistry	29 Aug 2016	34
45	Diffuse cavernous hemangioma of the uterus in a pregnant woman: report of a rare case and review of literature Renu K. Virk, Zhong Jiang, Di Lü · Archives of Gynecology and Obstetrics	4 Sep 2008	34
46	A Semisynthetic Quillaja Saponin as a Drug Delivery Agent for Aminoglycoside Antibiotics Joanne Recchia, Maria H. A. Lurantos, Jennifer A. Amsden et al. · Pharmaceutical Research	Dec 1995	34
47	Temporal expression of HIV-1 envelope proteins in baculovirus-infected insect cells: Implications for glycosylation and CD4 binding Cheryl Isaac Murphy, Michael Lennick, Sophie M. Lehar et al. · Gene Analysis Techniques	Oct 1990	33
48	Interleukin-12 enhances antigen-specific proliferation of peripheral blood mononuclear cells from HIV-positive and negative donors in response to Mycobacterium avium G W Newman, Joseph R. Guarnaccia, Estil A. Vance et al. · AIDS	Oct 1994	33
49	Development of a Single-Shot Subunit Vaccine for HIV-1. 3. Effect of Adjuvant and Immunization Schedule on the Duration of the Humoral Immune Response to Recombinant MN gp120 Jeffrey L. Cleland, Lorena Barrón, Ann L. Daugherty et al. · Journal of Pharmaceutical Sciences	Dec 1996	30
50	Adjuvant activity of QS-21 for experimental E. coli 018 polysaccharide vaccines Richard T. Coughlin, Ali Fattom, Chiayung Chu et al. · Vaccine	1995	29

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.