Most cited papers from EKOS Corporation

EKOS Corporation

What are the most cited papers from EKOS Corporation?

The most cited paper from EKOS Corporation is "Differential Expression of Chemokine Receptors and Chemotactic Responsiveness of Type 1 T Helper Cells (Th1s) and Th2s" (Raffaella Bonecchi, Giancarlo Bianchi, Paola Panina‐Bordignon et al., 1998), with 2,042 citations. Next come "Dynamic Changes of BRCA1 Subnuclear Location and Phosphorylation State Are Initiated by DNA Damage" (908) and "Use of an oriented peptide library to determine the optimal substrates of protein kinases" (669).

Published TypeFieldAccessCitations

Showing 50 of 60 papers. Every paper with more than 150 citations is listed.

Most cited papers, sortable by citations and release date
#	Paper
1	Differential Expression of Chemokine Receptors and Chemotactic Responsiveness of Type 1 T Helper Cells (Th1s) and Th2s Raffaella Bonecchi, Giancarlo Bianchi, Paola Panina‐Bordignon et al. · The Journal of Experimental Medicine Open access	5 Jan 1998	2,042
2	Dynamic Changes of BRCA1 Subnuclear Location and Phosphorylation State Are Initiated by DNA Damage Ralph Scully, Junjie Chen, Robert Ochs et al. · Cell Open access	Aug 1997	908
3	Use of an oriented peptide library to determine the optimal substrates of protein kinases Zhou Songyang, Steven Blechner, Nicole Hoagland et al. · Current Biology	Nov 1994	669
4	Association of Protein Kinase A and Protein Phosphatase 2B with a Common Anchoring Protein Vincent M. Coghlan, Brian A. Perrino, Monique L. Howard et al. · Science	6 Jan 1995	624
5	A Structural Basis for Substrate Specificities of Protein Ser/Thr Kinases: Primary Sequence Preference of Casein Kinases I and II, NIMA, Phosphorylase Kinase, Calmodulin-Dependent Kinase II, CDK5, and Erk1 Zhou Songyang, Kun Ping Lu, Young T. Kwon et al. · Molecular and Cellular Biology Open access	Nov 1996	555
6	Anti-inflammatory properties of a platelet-activating factor acetylhydrolase Larry W. Tjoelker, Cheryl Wilder, Chris Eberhardt et al. · Nature	Apr 1995	531
7	Human Macrophage–derived Chemokine (MDC), a Novel Chemoattractant for Monocytes, Monocyte-derived Dendritic Cells, and Natural Killer Cells Ronald Godiska, David Chantry, Carol J. Raport et al. · The Journal of Experimental Medicine Open access	5 May 1997	489
8	Molecular Cloning and Functional Characterization of a Novel Human CC Chemokine Receptor (CCR5) for RANTES, MIP-1β, and MIP-1α Carol J. Raport, Jennifa Gosling, Vicki L. Schweickart et al. · Journal of Biological Chemistry Open access	Jul 1996	454
9	A Crucial Role for the p110δ Subunit of Phosphatidylinositol 3-Kinase in B Cell Development and Activation Elizabeth A. Clayton, Giuseppe Bardi, Sarah E. Bell et al. · The Journal of Experimental Medicine Open access	9 Sep 2002	448
10	Costimulation of Fibroblast Collagen and Transforming Growth Factor β1 Gene Expression by Monocyte Chemoattractant Protein-1 via Specific Receptors Mehrnaz Gharaee‐Kermani, Elizabeth M. Denholm, Sem Hin Phan · Journal of Biological Chemistry Open access	Jul 1996	439
11	Macrophage-derived Chemokine Is a Functional Ligand for the CC Chemokine Receptor 4 Toshio Imai, David Chantry, Carol J. Raport et al. · Journal of Biological Chemistry Open access	1998	387
12	Tadalafil Relieves Lower Urinary Tract Symptoms Secondary to Benign Prostatic Hyperplasia Kevin T. McVary, Claus G. Roehrborn, Jed C. Kaminetsky et al. · The Journal of Urology	24 Mar 2007	376
13	Essential Role of Phosphoinositide 3-Kinase δ in Neutrophil Directional Movement Chanchal Sadhu, Boris P. Masinovsky, Ken O. Dick et al. · The Journal of Immunology	Mar 2003	367
14	Chemokine expression in murine experimental allergic encephalomyelitis Ronald Godiska, David Chantry, Gregory N. Dietsch et al. · Journal of Neuroimmunology	May 1995	356
15	Looking towards label-free biomolecular interaction analysis in a high-throughput format: a review of new surface plasmon resonance technologies Christina L. Boozer, Gi Bum Kim, Shuxin Cong et al. · Current Opinion in Biotechnology Review	12 Jul 2006	333
16	A Family of Human Phosphodiesterases Homologous to the Dunce Learning and Memory Gene Product of Drosophila melanogaster are Potential Targets for Antidepressant Drugs Graeme B. Bolger, Tamar Michaeli, Tim Martins et al. · Molecular and Cellular Biology Open access	Oct 1993	289
17	The Atr and Atm protein kinases associate with different sites along meiotically pairing chromosomes. Kathleen S. Keegan, Douglas A. Holtzman, Annemieke W. Plug et al. · Genes & Development Open access	Oct 1996	285
18	Platelet-activating factor acetylhydrolase deficiency. A missense mutation near the active site of an anti-inflammatory phospholipase. Diana M. Stafforini, K. Satoh, Donald L. Atkinson et al. · Journal of Clinical Investigation Open access	15 Jun 1996	269
19	A novel leukointegrin, αdβ2, binds preferentially to ICAM-3 Monica van der Vieren, Hai Le Trong, Christi L. Wood et al. · Immunity Open access	Dec 1995	258
20	p110δ, a Novel Phosphatidylinositol 3-Kinase Catalytic Subunit That Associates with p85 and Is Expressed Predominantly in Leukocytes David Chantry, Anne B. Vojtek, Adam Kashishian et al. · Journal of Biological Chemistry Open access	Aug 1997	252
21	Regulation of Class-Switch Recombination and Plasma Cell Differentiation by Phosphatidylinositol 3-Kinase Signaling Sidne A. Omori, Matthew H. Cato, Amy N. Anzelon-Mills et al. · Immunity Open access	29 Sep 2006	251
22	Stimulation of the DNA-dependent Protein Kinase by Poly(ADP-Ribose) Polymerase Tracy Ruscetti, Bruce E. Lehnert, James Halbrook et al. · Journal of Biological Chemistry Open access	Jun 1998	249
23	Inhibition of phosphoinositide 3‐kinase δ attenuates allergic airway inflammation and hyperresponsiveness in murine asthma model Kyung Sang Lee, Ho K. Lee, Joel S. Hayflick et al. · The FASEB Journal	28 Feb 2006	247
24	Essential role for the p110 isoform in phosphoinositide 3-kinase activation and cell proliferation in acute myeloid leukemia Pierre Sujobert · Blood	12 Apr 2005	245
25	Molecular Characterization of the Acute Inflammatory Response to Infections with Gram-Negative versus Gram-Positive Bacteria Robert J. Feezor, Caroline Oberholzer, Henry V. Baker et al. · Infection and Immunity Open access	19 Sep 2003	244
26	Endocan Is a Novel Chondroitin Sulfate/Dermatan Sulfate Proteoglycan That Promotes Hepatocyte Growth Factor/Scatter Factor Mitogenic Activity David Béchard, Thibaut Gentina, Maryse Delehedde et al. · Journal of Biological Chemistry Open access	Dec 2001	241
27	Isolation and characterization of cDNAs encoding PDE5A, a human cGMP-binding, cGMP-specific 3′,5′-cyclic nucleotide phosphodiesterase Kate Loughney, Teresa Hill, Vincent A. Florio et al. · Gene	Aug 1998	220
28	Plasma Platelet-activating Factor Acetylhydrolase Is a Secreted Phospholipase A2 with a Catalytic Triad Larry W. Tjoelker, Chris Eberhardt, Jeff Unger et al. · Journal of Biological Chemistry Open access	Oct 1995	218
29	Lovastatin biosynthesis in Aspergillus terreus: Characterization of blocked mutants, enzyme activities and a multifunctional polyketide synthase gene Lee E. Hendrickson, Claytus A. Davis, Claudia Roach et al. · Chemistry & Biology Open access	Jul 1999	217
30	Human Plasma Platelet-Activating Factor Acetyl hydrolase Diana M. Stafforini, Larry W. Tjoelker · Humana Press eBooks Book chapter	14 Nov 2003	216
31	On-demand IC351 (Cialis™) enhances erectile function in patients with erectile dysfunction Harin Padma-Nathan, J.E McMurray, W.T. Pullman et al. · International Journal of Impotence Research	Feb 2001	214
32	KSHV-encoded CC chemokine vMIP-III is a CCR4 agonist, stimulates angiogenesis, and selectively chemoattracts TH2 cells Johnny T. Stine, Christi L. Wood, Mark S. Hill et al. · Blood	15 Feb 2000	211
33	Isolation and characterization of PDE10A, a novel human 3′, 5′-cyclic nucleotide phosphodiesterase Kate Loughney, Peter B. Snyder, Lothar Uher et al. · Gene	Jun 1999	209
34	Indicator Cell Lines for Detection of Primary Strains of Human and Simian Immunodeficiency Viruses Marie A. Vodicka, Wei Chun Goh, Lily I. Wu et al. · Virology Open access	Jun 1997	207
35	Divergent Effects of Interleukin-4 and Interferon-γ on Macrophage-Derived Chemokine Production: An Amplification Circuit of Polarized T Helper 2 Responses Raffaella Bonecchi, Silvano Sozzani, Johnny T. Stine et al. · Blood	15 Oct 1998	205
36	Cloning and characterization of a new intercellular adhesion molecule ICAM-R Rosemay Vazeux, Patricia A. Hoffman, Judy K. Tomfta et al. · Nature	Dec 1992	204
37	Evaluation of the Efficacy and Safety of Once-a-Day Dosing of Tadalafil 5mg and 10mg in the Treatment of Erectile Dysfunction: Results of a Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial Hartmut Porst, François Giuliano, Sidney Glina et al. · European Urology	21 Mar 2006	201
38	Macrophage-derived chemokine (MDC) Alberto Mantovani, Patrick A. Gray, Jo Van Damme et al. · Journal of Leukocyte Biology	Sep 2000	197
39	A System for Production of Commercial Quantities of Human Lactoferrin: A Broad Spectrum Natural Antibiotic Pauline P. Ward, Christopher S. Piddington, Gráinne A. Cunningham et al. · Nature Biotechnology	May 1995	191
40	Characterization of five different proteins produced by alternatively spliced mRNAs from the human cAMP-specific phosphodiesterase PDE4D gene B. Graeme BOLGER, Suat Erdoğan, Eleanor R Jones et al. · Biochemical Journal Open access	Dec 1997	186
41	Changes in protein composition of meiotic nodules during mammalian meiosis Annemieke W. Plug, Antoine H.F.M. Peters, Kathleen S. Keegan et al. · Journal of Cell Science Open access	15 Feb 1998	177
42	Laser Stimulation of Auditory Neurons: Effect of Shorter Pulse Duration and Penetration Depth Agnella D. Izzo, Joseph T. Walsh, Heather Ralph et al. · Biophysical Journal Open access	11 Jan 2008	175
43	Presence of high contents of thymus and activation-regulated chemokine in platelets and elevated plasma levels of thymus and activation-regulated chemokine and macrophage-derived chemokine in patients with atopic dermatitis Takao Fujisawa, Ryuichi Fujisawa, Yoshiko Kato et al. · Journal of Allergy and Clinical Immunology Open access	Jul 2002	172
44	NMR Structure and Mutagenesis of the N-Terminal Dbl Homology Domain of the Nucleotide Exchange Factor Trio Xiaohong Liu, Hong Wang, Matthias Eberstadt et al. · Cell Open access	Oct 1998	172
45	p53 is phosphorylated in vitro and in vivo by the delta and epsilon isoforms of casein kinase 1 and enhances the level of casein kinase 1 delta in response to topoisomerase-directed drugs Uwe Knippschild, Diane M. MILNE, Linda E. Campbell et al. · Oncogene	2 Oct 1997	170
46	The structure of a bovine lung cGMP-binding, cGMP-specific phosphodiesterase deduced from a cDNA clone. Linda M. McAllister‐Lucas, W. K. Sonnenburg, A Kadlecek et al. · Journal of Biological Chemistry Open access	Oct 1993	170
47	Factors associated with health-related quality of life among hemodialysis patients in the DOPPS Antônio Alberto Lopes, Jennifer L. Bragg‐Gresham, David A. Goodkin et al. · Quality of Life Research Open access	7 Feb 2007	164
48	Analysis of Rad3 and Chk1 protein kinases defines different checkpoint responses Rui Gonçalo Martinho, Howard D. Lindsay, Gail Flaggs et al. · The EMBO Journal Open access	15 Dec 1998	161
49	Platelet-activating factor acetylhydrolases in health and disease Larry W. Tjoelker, Diana M. Stafforini · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids	Oct 2000	161
50	The role of endothelial PI3Kγ activity in neutrophil trafficking Kamal D. Puri, Teresa A. Doggett, Ching‐Yu Huang et al. · Blood Open access	16 Mar 2005	161

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.