Science Explorer Back to mapMap
Institution · Eli Lilly (Germany)

Most cited papers from Eli Lilly (Germany)

What are the most cited papers from Eli Lilly (Germany)?

The most cited paper from Eli Lilly (Germany) is "Ramucirumab plus paclitaxel versus placebo plus paclitaxel in patients with previously treated advanced gastric or gastro-oesophageal junction adenocarcinoma (RAINBOW): a double-blind, randomised phase 3 trial" (Hansjochen Wilke, Kei Muro, Eric Van Cutsem et al., 2014), with 2,505 citations. Next come "FGF-21 as a novel metabolic regulator" (2,126) and "The Differential Efficacy of Pemetrexed According to NSCLC Histology: A Review of Two Phase III Studies" (694).

Showing 50 of 60 papers. Every paper with more than 133 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Ramucirumab plus paclitaxel versus placebo plus paclitaxel in patients with previously treated advanced gastric or gastro-oesophageal junction adenocarcinoma (RAINBOW): a double-blind, randomised phase 3 trial Hansjochen Wilke, Kei Muro, Eric Van Cutsem et al. · The Lancet Oncology 17 Sep 2014 2,505
2 FGF-21 as a novel metabolic regulator Alexei Kharitonenkov, Tatiyana L. Shiyanova, Anja Köester et al. · Journal of Clinical Investigation Open access 3 May 2005 2,126
3 The Differential Efficacy of Pemetrexed According to NSCLC Histology: A Review of Two Phase III Studies Giorgio V. Scagliotti, Nasser H. Hanna, Frank V. Fossella et al. · The Oncologist Open access 16 Feb 2009 694
4 Social and Emotional Impairment in Children and Adolescents with ADHD and the Impact on Quality of Life Peter M. Wehmeier, Alexander Schacht, Russell A. Barkley · Journal of Adolescent Health 5 Jan 2010 631
5 Clinical development of galunisertib (LY2157299 monohydrate), a small molecule inhibitor of transforming growth factor-beta signaling pathway Michael M. F. Lahn, Stephan Herbertz, J. Scott Sawyer et al. · Drug Design Development and Therapy Open access Aug 2015 552
6 Fibroblast Growth Factor-21 Improves Pancreatic β-Cell Function and Survival by Activation of Extracellular Signal–Regulated Kinase 1/2 and Akt Signaling Pathways Wolf Wente, Alexander M. Efanov, Martin B. Brenner et al. · Diabetes Open access 25 Aug 2006 499
7 Necitumumab plus gemcitabine and cisplatin versus gemcitabine and cisplatin alone as first-line therapy in patients with stage IV squamous non-small-cell lung cancer (SQUIRE): an open-label, randomised, controlled phase 3 trial Nick Thatcher, Fred R. Hirsch, Alexander Luft et al. · The Lancet Oncology Open access 4 Jun 2015 484
8 A reference map of potential determinants for the human serum metabolome Noam Bar et al. · Nature Open access172 authors 11 Nov 2020 470
9 Insulin and Cortisol Promote Leptin Production in Cultured Human Fat Cells Martin Wabitsch, Per Bo Jensen, Werner Friedrich Blum et al. · Diabetes Oct 1996 463
10 Predictors and clinical consequences of non-adherence with antipsychotic medication in the outpatient treatment of schizophrenia Diego Novick, Josep María Haro, David L. Suarez et al. · Psychiatry Research 25 Feb 2010 454
11 Effects of Once-Weekly Dosing of a Long-Acting Release Formulation of Exenatide on Glucose Control and Body Weight in Subjects With Type 2 Diabetes Dennis S. Kim, Leigh MacConell, Dongliang Zhuang et al. · Diabetes Care Open access 25 May 2007 448
12 The Effect of Adding Exenatide to a Thiazolidinedione in Suboptimally Controlled Type 2 Diabetes Bernard Zinman, Byron J. Hoogwerf, Santiago Durán García et al. · Annals of Internal Medicine 3 Apr 2007 430
13 Interim analysis of the effects of exenatide treatment on A1C, weight and cardiovascular risk factors over 82 weeks in 314 overweight patients with type 2 diabetes Lawrence Blonde, ERIC J. KLEIN, J. Han et al. · Diabetes Obesity and Metabolism Open access 18 Apr 2006 419
14 Contribution of androgens to the gender difference in leptin production in obese children and adolescents. Martin Wabitsch, W. F. P. Blum, Rainer Muche et al. · Journal of Clinical Investigation Open access 15 Aug 1997 365
15 Dual EGFR-VEGF Pathway Inhibition: A Promising Strategy for Patients With EGFR-Mutant NSCLC Xiuning Le, Monique B. Nilsson, Jonathan Wade Goldman et al. · Journal of Thoracic Oncology Open access 20 Oct 2020 346
16 Levels of Leptin in Maternal Serum, Amniotic Fluid, and Arterial and Venous Cord Blood: Relation to Neonatal and Placental Weight Ch. Schubring, W. Kiess, Piera Englaro et al. · The Journal of Clinical Endocrinology & Metabolism May 1997 338
17 KRAS-Mutant non-small cell lung cancer: From biology to therapy Irene Ferrer, Jon Zugazagoitia, Stephan Herbertz et al. · Lung Cancer Open access 20 Jul 2018 333
18 Duloxetine and pregabalin: High-dose monotherapy or their combination? The “COMBO-DN study” – a multinational, randomized, double-blind, parallel-group study in patients with diabetic peripheral neuropathic pain Solomon Hailemariam Tesfaye, Stefan Wilhelm, Alberto García Lledó et al. · Pain 31 May 2013 312
19 Exenatide Augments First- and Second-Phase Insulin Secretion in Response to Intravenous Glucose in Subjects with Type 2 Diabetes Frauke Fehse, MICHAEL E. TRAUTMANN, Jens Juul Holst et al. · The Journal of Clinical Endocrinology & Metabolism Nov 2005 302
20 Triple hormone receptor agonist retatrutide for metabolic dysfunction-associated steatotic liver disease: a randomized phase 2a trial Arun Jayant Sanyal, Lee M. Kaplan, Juan P. Frías et al. · Nature Medicine Open access 10 Jun 2024 290
21 Genotypes and phenotypes in children with short stature: clinical indicators of SHOX haploinsufficiency Gudrun Rappold, W. F. Blum, Elena P. Shavrikova et al. · Journal of Medical Genetics Open access 20 Dec 2006 258
22 Effects of Tadalafil Treatment on Erectile Function Recovery Following Bilateral Nerve-sparing Radical Prostatectomy: A Randomised Placebo-controlled Study (REACTT) Francesco Montorsi, Gerald B Brock, Jens-Uwe Stolzenburg et al. · European Urology 12 Oct 2013 251
23 Testosterone Substitution Normalizes Elevated Serum Leptin Levels in Hypogonadal Men Friedrich Jockenhövel, Werner Friedrich Blum, Elisabeth Vogel et al. · The Journal of Clinical Endocrinology & Metabolism Aug 1997 251
24 Leptin suppresses semi-starvation induced hyperactivity in rats: implications for anorexia nervosa Cornelia Exner, Johannes Hebebrand, Helmut Remschmidt et al. · Molecular Psychiatry Open access Sep 2000 240
25 Leptin levels in patients with anorexia nervosa are reduced in the acute stage and elevated upon short-term weight restoration Johannes Hebebrand, Werner Friedrich Blum, Nikolaus Barth et al. · Molecular Psychiatry Jul 1997 230
26 Atomoxetine and methylphenidate treatment in children with ADHD: A prospective, randomized, open-label trial Regina Dittmann, D.S. Fouche, Christopher J. Kratochvil et al. · European Neuropsychopharmacology 2001 223
27 Hepatic and glucagon-like peptide-1–mediated reversal of diabetes by glucagon receptor antisense oligonucleotide inhibitors Kyle W. Sloop et al. · Journal of Clinical Investigation Open access Jun 2004 215
28 Costs Associated With Treatment of Chronic Low Back Pain Jihyung Hong, Catherine C. Reed, Diego Novick et al. · Spine 4 Oct 2012 213
29 Molecular and prognostic distinction between serous ovarian carcinomas of varying grade and malignant potential Ivo M. Meinhold-Heerlein, Dirk Bauerschlag, Felix Hilpert et al. · Oncogene 22 Nov 2004 208
30 Diabetes at the crossroads: relevance of disease classification to pathophysiology and treatment Richard David Leslie, Jerry P. Palmer, Nanette Cathrin Schloot et al. · Diabetologia Open access 24 Oct 2015 207
31 Drug Liposome Partitioning as a Tool for the Prediction of Human Passive Intestinal Absorption K. Balon, Bernd U. Riebesehl, Bernhard W. Müller · Pharmaceutical Research Jun 1999 199
32 Integrative Analysis Reveals a Molecular Stratification of Systemic Autoimmune Diseases Guillermo Barturen et al. · Arthritis & Rheumatology Open access132 authors 8 Dec 2020 196
33 Identification of 70 calcium-sensing receptor mutations in hyper- and hypo-calcaemic patients: evidence for clustering of extracellular domain mutations at calcium-binding sites Fadil M. Hannan et al. · Human Molecular Genetics 14 Mar 2012 192
34 Multilevel Network Meta-Regression for Population-Adjusted Treatment Comparisons David Phillippo, Sofia Dias, A. E. Ades et al. · Journal of the Royal Statistical Society Series A (Statistics in Society) Open access Jun 2020 186
35 Non?stimulant medications in the treatment of ADHD Tobias Banaschewski, Veit Roessner, R.W. Dittmann et al. · European Child & Adolescent Psychiatry Jul 2004 185
36 Leptin Production and Release in the Duallyin VitroPerfused Human Placenta1 Knud Linnemann, Antoine Malek, Ruth Sager et al. · The Journal of Clinical Endocrinology & Metabolism Open access Nov 2000 185
37 Clozapine and Olanzapine Are Associated With Food Craving and Binge Eating Michael Kluge, Andreas Schuld, Hubertus Himmerich et al. · Journal of Clinical Psychopharmacology Dec 2007 178
38 Gemcitabine and cisplatin in the treatment of advanced or metastatic pancreatic cancer Volker Heinemann, Hansjochen Wilke, H.‐G. Mergenthaler et al. · Annals of Oncology Open access Nov 2000 172
39 Low leptin levels predict amenorrhea in underweight and eating disordered females Wolfgang Kopp, Werner Friedrich Blum, S von Prittwitz et al. · Molecular Psychiatry Jul 1997 172
40 Serum leptin levels increase rapidly after initiation of clozapine therapy T. Brömel, Werner Friedrich Blum, Andreas Ziegler et al. · Molecular Psychiatry 1998 170
41 Dexamethasone Induces an Acute and Sustained Rise in Circulating Leptin Levels in Normal Human Subjects JOHN P. MIELL, P. Engloro, Werner Friedrich Blum · Hormone and Metabolic Research Dec 1996 169
42 Nonparametric Analysis of Ordered Categorical Data in Designs with Longitudinal Observations and Small Sample Sizes Edgar Brunner, Frank Langer · Biometrical Journal Oct 2000 165
43 ATP-Sensitive K+ Channel–Dependent Regulation of Glucagon Release and Electrical Activity by Glucose in Wild-Type and SUR1−/− Mouse α-Cells Jesper Gromada, Xiaosong Ma, Marianne Høy et al. · Diabetes Open access Dec 2004 165
44 Rates and predictors of remission and recovery during 3 years in 392 never‐treated patients with schizophrenia Martin Lambert, Dieter Naber, Alexander Schacht et al. · Acta Psychiatrica Scandinavica 4 Aug 2008 161
45 Exenatide twice daily versus glimepiride for prevention of glycaemic deterioration in patients with type 2 diabetes with metformin failure (EUREXA): an open-label, randomised controlled trial Baptist Gallwitz, Juan M. Sánchez‐Guzmán, Francesco Dotta et al. · The Lancet Jun 2012 160
46 Glucose Stimulates Glucagon Release in Single Rat α-Cells by Mechanisms that Mirror the Stimulus-Secretion Coupling in β-Cells Hervør Lykke Olsen, Sten S. Theander, Krister B. Bokvist et al. · Endocrinology Open access 5 Aug 2005 160
47 Front-line treatment of advanced non-small-cell lung cancer with MTA (LY231514, Pemetrexed disodium, ALIMTA™ and cisplatin: A multicenter phase II trial C. Manegold, Ulrich Gatzemeier, Joachim von Pawel et al. · Annals of Oncology Open access Apr 2000 156
48 Parathyroid hormone increases the concentration of insulin-like growth factor-I and transforming growth factor beta 1 in rat bone. Johannes Pfeilschifter, F Laukhuf, B. Müller‐Beckmann et al. · Journal of Clinical Investigation Open access Aug 1995 155
49 Clinical and Pharmacokinetic Phase I Study of Multitargeted Antifolate (LY231514) in Combination With Cisplatin Ralf Thödtmann, Henrik Depenbrock, Herlinde Dumez et al. · Journal of Clinical Oncology Oct 1999 151
50 A review of hemolytic uremic syndrome in patients treated with gemcitabine therapy Man C. Fung, Anna Maria Storniolo, Binh Vu Nguyen et al. · Cancer Open access May 1999 150

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.