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Most cited papers from EMC Microcollections (Germany)

What are the most cited papers from EMC Microcollections (Germany)?

The most cited paper from EMC Microcollections (Germany) is "Inactivation of the dlt Operon inStaphylococcus aureus Confers Sensitivity to Defensins, Protegrins, and Other Antimicrobial Peptides" (Andreas Peschel, Michael J. Otto, Ralph W. Jack et al., 1999), with 1,010 citations. Next come "Staphylococcus aureus Resistance to Human Defensins and Evasion of Neutrophil Killing via the Novel Virulence Factor Mprf Is Based on Modification of Membrane Lipids with l -Lysine" (790) and "Heterodimerization of TLR2 with TLR1 or TLR6 expands the ligand spectrum but does not lead to differential signaling" (323).

Showing 50 of 60 papers. Every paper with more than 21 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Inactivation of the dlt Operon inStaphylococcus aureus Confers Sensitivity to Defensins, Protegrins, and Other Antimicrobial Peptides Andreas Peschel, Michael J. Otto, Ralph W. Jack et al. · Journal of Biological Chemistry Open access Mar 1999 1,010
2 Staphylococcus aureus Resistance to Human Defensins and Evasion of Neutrophil Killing via the Novel Virulence Factor Mprf Is Based on Modification of Membrane Lipids with l -Lysine Andreas Peschel, Ralph W. Jack, Michael J. Otto et al. · The Journal of Experimental Medicine Open access 7 May 2001 790
3 Heterodimerization of TLR2 with TLR1 or TLR6 expands the ligand spectrum but does not lead to differential signaling Katja Farhat, Sabine Riekenberg, Holger Heine et al. · Journal of Leukocyte Biology 3 Dec 2007 323
4 Activation of Toll-Like Receptor 2 on Human Tracheobronchial Epithelial Cells Induces the Antimicrobial Peptide Human β Defensin-2 Cheryl J. Hertz, Qi Wu, Edith Martin Porter et al. · The Journal of Immunology Dec 2003 282
5 TLR1- and TLR6-independent Recognition of Bacterial Lipopeptides Ute Buwitt‐Beckmann, Holger Heine, Karl‐Heinz Wiesmüller et al. · Journal of Biological Chemistry Open access 2 Feb 2006 256
6 Toll‐like receptor 6‐independent signaling by diacylated lipopeptides Ute Buwitt‐Beckmann, Holger Heine, Karl‐Heinz Wiesmüller et al. · European Journal of Immunology 3 Dec 2004 207
7 Early neutralizing IgG response to Chikungunya virus in infected patients targets a dominant linear epitope on the E2 glycoprotein Yiu‐Wing Kam, Fok‐Moon Lum, Teck‐Hui Teo et al. · EMBO Molecular Medicine Open access 5 Mar 2012 202
8 H-2 class I knockout, HLA-A2.1-transgenic mice: a versatile animal model for preclinical evaluation of antitumor immunotherapeutic strategies Hüseyin Firat, Francisco Garcia‐Pons, Sophie Tourdot et al. · European Journal of Immunology Open access Oct 1999 176
9 Binding of lipopeptide to CD14 induces physical proximity of CD14, TLR2 and TLR1 Maria Manukyan, Kathy Triantafilou, Martha Triantafilou et al. · European Journal of Immunology Open access 15 Feb 2005 151
10 Lantibiotics and microcins: polypeptides with unusual chemical diversity Ralph W. Jack, Günther Jung · Current Opinion in Chemical Biology Review Jun 2000 135
11 Extensive Post-translational Modification, Including Serine to d-Alanine Conversion, in the Two-component Lantibiotic, Lacticin 3147 Máire P. Ryan, Ralph W. Jack, Michaele Josten et al. · Journal of Biological Chemistry Open access Dec 1999 135
12 Synthetic lipopeptide adjuvants and Toll-like receptor 2—structure–activity relationships Renate Spohn, Ute Buwitt‐Beckmann, Roland E. Brock et al. · Vaccine 9 Apr 2004 133
13 Lipopeptide structure determines TLR2 dependent cell activation level Ute Buwitt‐Beckmann, Holger Heine, Karl‐Heinz Wiesmüller et al. · FEBS Journal Open access Dec 2005 110
14 Structure–function relationships in the tryptophan‐rich, antimicrobial peptide indolicidin Petra Staubitz, Andreas Peschel, Willem F. Nieuwenhuizen et al. · Journal of Peptide Science 24 Sep 2001 106
15 A Fluorescence-Based Synthetic LPS Sensor Söhnke Voss, Rainer Fischer, Günther Jung et al. · Journal of the American Chemical Society 30 Dec 2006 91
16 Bidirectional binding of invariant chain peptides to an MHC class II molecule Sebastian Günther, Andreas Schlundt, Jana Sticht et al. · Proceedings of the National Academy of Sciences Open access 29 Nov 2010 81
17 Identification of T-cell epitopes in the structural and non-structural proteins of classical swine fever virus Elisenda Armengol, Karl‐Heinz Wiesmüller, Daniel Wienhold et al. · Journal of General Virology Mar 2002 81
18 Combinatorial peptide libraries reveal the ligand-binding mechanism of the oligopeptide receptor OppA of Lactococcus lactis Frank J. M. Detmers, Frank C. Lanfermeijer, Rupert Abele et al. · Proceedings of the National Academy of Sciences Open access 24 Oct 2000 79
19 NSP4 Is Stored in Azurophil Granules and Released by Activated Neutrophils as Active Endoprotease with Restricted Specificity Natascha C. Perera, Karl‐Heinz Wiesmüller, Maria Torp Larsen et al. · The Journal of Immunology Open access Aug 2013 79
20 The Bactericidal Activity of Pediocin PA-1 Is Specifically Inhibited by a 15-mer Fragment That Spans the Bacteriocin from the Center toward the C Terminus Gunnar Fimland, Ralph W. Jack, Günther Jung et al. · Applied and Environmental Microbiology Open access Dec 1998 76
21 CyLoP-1: A Novel Cysteine-Rich Cell-Penetrating Peptide for Cytosolic Delivery of Cargoes Deepti Jha, Ritu Kumar Mishra, Sven Gottschalk et al. · Bioconjugate Chemistry 14 Feb 2011 76
22 A new synthetic toll-like receptor 1/2 ligand is an efficient adjuvant for peptide vaccination in a human volunteer Hans-Georg Rammensee et al. · Journal for ImmunoTherapy of Cancer Open access 15 Nov 2019 72
23 Modular Multiantigen T Cell Epitope–Enriched DNA Vaccine Against Human Leishmaniasis Shantanabha Das, Anja Freier, Thouraya Boussoffara et al. · Science Translational Medicine 30 Apr 2014 72
24 The Synthetic Bacterial Lipopeptide Pam3CSK4 Modulates Respiratory Syncytial Virus Infection Independent of TLR Activation D. Tien Nguyen, Lot D. de Witte, Martin Ludlow et al. · PLoS Pathogens Open access 19 Aug 2010 68
25 Identification of Foot-and-Mouth Disease Virus-Specific Linear B-Cell Epitopes To Differentiate between Infected and Vaccinated Cattle Bettina-Judith Höhlich, Karl‐Heinz Wiesmüller, Tobias Schlapp et al. · Journal of Virology Open access 28 Jul 2003 68
26 Lipoproteins/peptides are sepsis-inducing toxins from bacteria that can be neutralized by synthetic anti-endotoxin peptides Guillermo Martínez de Tejada, Lena Heinbockel, Raquel Ferrer‐Espada et al. · Scientific Reports Open access 22 Sep 2015 63
27 In situ assembly of macromolecular complexes triggered by light Christian Grunwald, Katrin Schulze, Annett Reichel et al. · Proceedings of the National Academy of Sciences Open access 3 Mar 2010 59
28 Physicochemical and Biological Analysis of Synthetic Bacterial Lipopeptides Andra Beate Schromm, Jörg Howe, Artur Jochen Ulmer et al. · Journal of Biological Chemistry Open access 18 Feb 2007 56
29 Conformation of peptides bound to the transporter associated with antigen processing (TAP) Meike Herget, Christoph Baldauf, Christian Wilfried Scholz et al. · Proceedings of the National Academy of Sciences Open access 4 Jan 2011 51
30 High Immunogenicity of Intracellular Myelin Oligodendrocyte Glycoprotein Epitopes Robert Weissert, Jens Kühle, Katrien L. de Graaf et al. · The Journal of Immunology Open access Jul 2002 51
31 Identification of novel foot-and-mouth disease virus specific T-cell epitopes in c/c and d/d haplotype miniature swine Wilhelm Gerner, M. Denyer, Haru‐Hisa Takamatsu et al. · Virus Research 29 Aug 2006 50
32 An Antifungal Benzimidazole Derivative Inhibits Ergosterol Biosynthesis and Reveals Novel Sterols Petra Keller, Christoph Müller, Isabel Engelhardt et al. · Antimicrobial Agents and Chemotherapy Open access 28 Jul 2015 49
33 Mimotopes for tumor-specific T lymphocytes in human cancer determined with combinatorial peptide libraries Thomas Linnemann, Tumenjargal Sherev, Sylke Gellrich et al. · European Journal of Immunology Open access 2001 46
34 Biofunctionalized peptide-based hydrogels provide permissive scaffolds to attract neurite outgrowth from spiral ganglion neurons Claudia Frick, Marcus Müller, Ute Wank et al. · Colloids and Surfaces B Biointerfaces Open access 8 Oct 2016 43
35 Peptide Vaccines and Peptide Libraries Karl‐Heinz Wiesmüller, Burkhard T. Fleckenstein, Günther Jung · Biological Chemistry 27 Jan 2001 42
36 NANOCI—Nanotechnology Based Cochlear Implant With Gapless Interface to Auditory Neurons Pascal Senn et al. · Otology & Neurotology Open access 12 Aug 2017 41
37 Phase I/II trial of a peptide-based COVID-19 T-cell activator in patients with B-cell deficiency Jonas S. Heitmann et al. · Nature Communications Open access 18 Aug 2023 36
38 A new cell-based innate immune receptor assay for the examination of receptor activity, ligand specificity, signalling pathways and the detection of pyrogens Anke Burger‐Kentischer, Ina S. Abele, Doris Finkelmeier et al. · Journal of Immunological Methods 11 Apr 2010 36
39 Succinimidyl Carbamate Derivatives from N‐Protected α‐Amino Acids and Dipeptides―Synthesis of Ureidopeptides and Oligourea/Peptide Hybrids Lucile Fischer, Vincent Semetey, José Manuel Lozano et al. · European Journal of Organic Chemistry Open access 28 Mar 2007 35
40 Regulators of G‐protein signalling are modulated by bacterial lipopeptides and lipopolysaccharide Sabine Riekenberg, Katja Farhat, Jennifer Debarry et al. · FEBS Journal Open access 16 Dec 2008 35
41 Synthesis and cellular uptake of a MR contrast agent coupled to an antisense peptide nucleic acid – cell– penetrating peptide conjugate Wu Su, Ritu Kumar Mishra, Josef Pfeuffer et al. · Contrast Media & Molecular Imaging 2007 34
42 Designing a SARS-CoV-2 T-Cell-Inducing Vaccine for High-Risk Patient Groups Hans‐Georg Rammensee, Cécile Gouttefangeas, Sonja Heidu et al. · Vaccines Open access 24 Apr 2021 33
43 Silica‐based monoliths for rapid peptide screening by capillary liquid chromatography hyphenated with electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry Felix Christian Leinweber, Dietmar G. Schmid, Dieter Lubda et al. · Rapid Communications in Mass Spectrometry 24 Apr 2003 31
44 Detection of human serum antibodies against type-specifically reactive peptides from the N-terminus of glycoprotein B of herpes simplex virus type 1 and type 2 by surface plasmon resonance Claus Wittekindt, Burkhard T. Fleckenstein, Karl‐Heinz Wiesmüller et al. · Journal of Virological Methods Jun 2000 31
45 Highly resolved dose–response functions for drug-modulated bacteria cultivation obtained by fluorometric and photometric flow-through sensing in microsegmented flow Anette Funfak, Regina Hartung, Jialan Cao et al. · Sensors and Actuators B Chemical 22 Jul 2009 31
46 Influence of the Vehicle on the Penetration of Particles into Hair Follicles Alexa Patzelt, Heike Richter, Lars Dähne et al. · Pharmaceutics Open access 14 Jun 2011 30
47 Immunostimulation by bacterial components: I. Activation of macrophages and enhancement of genetic immunization by the lipopeptide P3CSK4 Ulrich vor dem Esche, Mohammed Akli Ayoub, S.D.C Pfannes et al. · International Journal of Immunopharmacology Dec 2000 28
48 Induction of an antigen-specific immune response and partial protection of cattle against challenge infection with foot-and-mouth disease virus (FMDV) after lipopeptide vaccination with FMDV-specific B-cell epitopes Bettina-Judith Höhlich, Karl‐Heinz Wiesmüller, Bernd Haas et al. · Journal of General Virology 26 Nov 2003 28
49 Synthesis of the Antibiotic ( R )‐Reutericyclin via Dieckmann Condensation Roswitha M. Böhme, Günther Jung, Eberhard Breitmaier · Helvetica Chimica Acta Nov 2005 27
50 Optical Biosensors. Monitoring Studies of Glycopeptide Antibiotic Fermentation Using White Light Interference Rolf Tünnemann, Martin Mehlmann, Roderich D. Süßmuth et al. · Analytical Chemistry 2 Aug 2001 27

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.