Institution · Enamine (Ukraine)
Most cited papers from Enamine (Ukraine)
Enamine (Ukraine)
What are the most cited papers from Enamine (Ukraine)?
The most cited paper from Enamine (Ukraine) is "Ultra-large library docking for discovering new chemotypes" (Jiankun Lyu, Sheng Wang, Trent E. Balius et al., 2019), with 1,039 citations. Next come "An open-source drug discovery platform enables ultra-large virtual screens" (689) and "Saturated bioisosteres of benzene: where to go next?" (634).
Showing 50 of 60 papers. Every paper with more than 70 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Ultra-large library docking for discovering new chemotypes Jiankun Lyu, Sheng Wang, Trent E. Balius et al. · Nature | 6 Feb 2019 | 1,039 |
| 2 | An open-source drug discovery platform enables ultra-large virtual screens Christoph Gorgulla, Andras Boeszoermenyi, Zifu Wang et al. · Nature | 9 Mar 2020 | 689 |
| 3 | Saturated bioisosteres of benzene: where to go next? Pavel K. Mykhailiuk · Organic & Biomolecular Chemistry | 2019 | 634 |
| 4 | Synthon-based ligand discovery in virtual libraries of over 11 billion compounds Arman A. Sadybekov, Anastasiia Sadybekov, Yongfeng Liu et al. · Nature | 15 Dec 2021 | 454 |
| 5 | Hindered dialkyl ether synthesis with electrogenerated carbocations Jinbao Xiang, Ming Shang, Yu Kawamata et al. · Nature | 9 Sep 2019 | 399 |
| 6 | Virtual discovery of melatonin receptor ligands to modulate circadian rhythms Reed M. Stein, Hye Jin Kang, John D. McCorvy et al. · Nature | 10 Feb 2020 | 326 |
| 7 | Fluorinated Pyrazoles: From Synthesis to Applications Pavel K. Mykhailiuk · Chemical Reviews | 31 Dec 2020 | 296 |
| 8 | A Radical Approach to Anionic Chemistry: Synthesis of Ketones, Alcohols, and Amines Shengyang Ni, Natalia M. Padial, Cian Kingston et al. · Journal of the American Chemical Society | 3 Apr 2019 | 246 |
| 9 | Generating Multibillion Chemical Space of Readily Accessible Screening Compounds Oleksandr O. Grygorenko, Dmytro S. Radchenko, Igor Dziuba et al. · iScience | 15 Oct 2020 | 223 |
| 10 | Saturated Bioisosteres of ortho ‐Substituted Benzenes Aleksandr Denisenko, Pavel Garbuz, Svitlana Valentinovna Shishkina et al. · Angewandte Chemie International Edition | 14 Jul 2020 | 221 |
| 11 | Structures of the σ2 receptor enable docking for bioactive ligand discovery Assaf Alon, Jiankun Lyu, João M. Bráz et al. · Nature | 8 Dec 2021 | 205 |
| 12 | Open science discovery of potent noncovalent SARS-CoV-2 main protease inhibitors Melissa L. Boby et al. · Science | 9 Nov 2023 | 188 |
| 13 | Difluoro-Substituted Bicyclo[1.1.1]pentanes for Medicinal Chemistry: Design, Synthesis, and Characterization Roman Bychek, Valeriia Hutskalova, Yuliya P. Bas et al. · The Journal of Organic Chemistry | 25 Sep 2019 | 188 |
| 14 | Water‐Soluble Non‐Classical Benzene Mimetics Vadym V. Levterov, Yaroslav Panasyuk, Valentyna O. Pivnytska et al. · Angewandte Chemie International Edition | 15 Feb 2020 | 186 |
| 15 | 2,2,2-Trifluorodiazoethane (CF 3 CHN 2 ): A Long Journey since 1943 Pavel K. Mykhailiuk · Chemical Reviews | 17 Sep 2020 | 183 |
| 16 | The Symbiotic Relationship Between Drug Discovery and Organic Chemistry Oleksandr O. Grygorenko, Dmitriy M. Volochnyuk, Sergey V. Ryabukhin et al. · Chemistry - A European Journal | 20 Aug 2019 | 183 |
| 17 | 2-Oxabicyclo[2.1.1]hexanes as saturated bioisosteres of the ortho-substituted phenyl ring Aleksandr Denisenko, Pavel Garbuz, Nataliya M. Voloshchuk et al. · Nature Chemistry | 5 Jun 2023 | 168 |
| 18 | Structure-based discovery of nonopioid analgesics acting through the α 2A -adrenergic receptor Elissa A. Fink et al. · Science | 29 Sep 2022 | 164 |
| 19 | Controlling Biological Activity with Light: Diarylethene‐Containing Cyclic Peptidomimetics Oleg Babii, Sergii Afonin, Marina Berditsch et al. · Angewandte Chemie International Edition | 19 Feb 2014 | 163 |
| 20 | AlphaFold2 structures guide prospective ligand discovery Jiankun Lyu et al. · Science | 16 May 2024 | 161 |
| 21 | A Practical and Scalable Approach to Fluoro‐Substituted Bicyclo[1.1.1]pentanes Roman Bychek, Pavel K. Mykhailiuk · Angewandte Chemie International Edition | 31 May 2022 | 151 |
| 22 | In Situ Generation of Difluoromethyl Diazomethane for [3+2] Cycloadditions with Alkynes Pavel K. Mykhailiuk · Angewandte Chemie International Edition | 20 Mar 2015 | 150 |
| 23 | Overcoming Limitations in Decarboxylative Arylation via Ag–Ni Electrocatalysis Maximilian D. Palkowitz et al. · Journal of the American Chemical Society | 15 Sep 2022 | 143 |
| 24 | Iterative computational design and crystallographic screening identifies potent inhibitors targeting the Nsp3 macrodomain of SARS-CoV-2 Stefan Gahbauer et al. · Proceedings of the National Academy of Sciences | 4 Jan 2023 | 136 |
| 25 | Emerging Building Blocks for Medicinal Chemistry: Recent Synthetic Advances Oleksandr O. Grygorenko, Dmitriy M. Volochnyuk, Bohdan V. Vashchenko · European Journal of Organic Chemistry | 8 Sep 2021 | 132 |
| 26 | Synthesis of Trifluoromethyl‐Substituted Proline Analogues as 19F NMR Labels for Peptides in the Polyproline II Conformation Pavel K. Mykhailiuk, Sergii Afonin, Gennady V. Palamarchuk et al. · Angewandte Chemie International Edition | 24 Jun 2008 | 125 |
| 27 | One‐Pot Synthesis of CF3‐Substituted Pyrazolines/Pyrazoles from Electron‐Deficient Alkenes/Alkynes and CF3CHN2 Generated in situ: Optimized Synthesis of Tris(trifluoromethyl)pyrazole Evgeniy Yu. Slobodyanyuk, Olexiy S. Artamonov, Олег В. Шишкин et al. · European Journal of Organic Chemistry | 5 Mar 2014 | 121 |
| 28 | Trifluoromethyl-substituted cyclopropanes Oleksandr O. Grygorenko, Oleksiy S. Artamonov, Igor V. Komarov et al. · Tetrahedron | 25 Nov 2010 | 120 |
| 29 | Bicyclic Conformationally Restricted Diamines Oleksandr O. Grygorenko, Dmytro S. Radchenko, Dmitriy M. Volochnyuk et al. · Chemical Reviews | 28 Jun 2011 | 118 |
| 30 | A Close-up Look at the Chemical Space of Commercially Available Building Blocks for Medicinal Chemistry Yuliana Zabolotna, Dmitriy M. Volochnyuk, Sergey V. Ryabukhin et al. · Journal of Chemical Information and Modeling | 20 Dec 2021 | 117 |
| 31 | Conformationally Rigid Trifluoromethyl‐Substituted α‐Amino Acid Designed for Peptide Structure Analysis by Solid‐State 19F NMR Spectroscopy Pavel K. Mikhailiuk, Sergii Afonin, Alexander N. Chernega et al. · Angewandte Chemie International Edition | 25 Jul 2006 | 114 |
| 32 | Catalytic undirected borylation of tertiary C–H bonds in bicyclo[1.1.1]pentanes and bicyclo[2.1.1]hexanes Isaac Furay Yu, Jenna L. Manske, Alejandro Diéguez-Vázquez et al. · Nature Chemistry | 27 Mar 2023 | 113 |
| 33 | General Synthesis of 3‐Azabicyclo[3.1.1]heptanes and Evaluation of Their Properties as Saturated Isosteres** Dmitry Dibchak, Mariya Snisarenko, Artem Mishuk et al. · Angewandte Chemie International Edition | 26 May 2023 | 112 |
| 34 | Generative and reinforcement learning approaches for the automated de novo design of bioactive compounds Maria Korshunova, Niles Huang, Stephen J. Capuzzi et al. · Communications Chemistry | 18 Oct 2022 | 112 |
| 35 | Photochemical In-Flow Synthesis of 2,4-Methanopyrrolidines: Pyrrolidine Analogues with Improved Water Solubility and Reduced Lipophilicity Vadym V. Levterov, Oleg Michurin, Petro Borysko et al. · The Journal of Organic Chemistry | 25 Oct 2018 | 106 |
| 36 | Electrochemical C(sp3)–H Fluorination Yusuke Takahira, Miao Chen, Yu Kawamata et al. · Synlett | Mar 2019 | 105 |
| 37 | Quaternary Centers by Nickel‐Catalyzed Cross‐Coupling of Tertiary Carboxylic Acids and (Hetero)Aryl Zinc Reagents Tie‐Gen Chen, Haolin Zhang, Pavel K. Mykhailiuk et al. · Angewandte Chemie International Edition | 9 Jan 2019 | 105 |
| 38 | Fluorinated Cycloalkyl Building Blocks for Drug Discovery Oleksandr O. Grygorenko, Kostiantyn P. Melnykov, Serhii M. Holovach et al. · ChemMedChem | 29 Aug 2022 | 104 |
| 39 | How Accurately Can We Predict the Melting Points of Drug-like Compounds? Igor V. Tetko, Yurii Sushko, Sergii Novotarskyi et al. · Journal of Chemical Information and Modeling | 9 Dec 2014 | 104 |
| 40 | 1,2-Disubstituted bicyclo[2.1.1]hexanes as saturated bioisosteres of ortho -substituted benzene Aleksandr Denisenko, Pavel Garbuz, Yelyzaveta Makovetska et al. · Chemical Science | 2023 | 96 |
| 41 | Rapid and Scalable Halosulfonylation of Strain‐Release Reagents** Helena D. Pickford, Vasyl Ripenko, Ryan E. McNamee et al. · Angewandte Chemie International Edition | 13 Oct 2022 | 93 |
| 42 | Synthesis of Multifunctional Spirocyclic Azetidines and Their Application in Drug Discovery Alexander A. Kirichok, Irina O. Shton, Iryna Pishel et al. · Chemistry - A European Journal | 16 Jan 2018 | 93 |
| 43 | A multi-pronged approach targeting SARS-CoV-2 proteins using ultra-large virtual screening Christoph Gorgulla et al. · iScience | 10 Jan 2021 | 92 |
| 44 | 1‐Substituted 2‐Azaspiro[3.3]heptanes: Overlooked Motifs for Drug Discovery Alexander A. Kirichok, Iryna Shton, Maria Kliachyna et al. · Angewandte Chemie International Edition | 16 May 2017 | 92 |
| 45 | Effect of gem ‐Difluorination on the Key Physicochemical Properties Relevant to Medicinal Chemistry: The Case of Functionalized Cycloalkanes Sergey Holovach, Kostiantyn P. Melnykov, Artem Skreminskiy et al. · Chemistry - A European Journal | 11 Feb 2022 | 91 |
| 46 | Studies an Acetylenic Compounds. XXIII. A New Ring Closure of 2-Propynyl Ethers Issei Iwai, Junya Ide · Chemical and Pharmaceutical Bulletin | 1962 | 90 |
| 47 | Heterometallic Coordination Polymers Assembled from Trigonal Trinuclear Fe2Ni-Pivalate Blocks and Polypyridine Spacers: Topological Diversity, Sorption, and Catalytic Properties Svitlana Sotnik, R.A. Polunin, Mikhail A. Kiskin et al. · Inorganic Chemistry | 8 May 2015 | 89 |
| 48 | Role of Protein Phosphatase 1 in Dephosphorylation of Ebola Virus VP30 Protein and Its Targeting for the Inhibition of Viral Transcription Philipp A. Ilinykh, Bersabeh Tigabu, Andrey I. Ivanov et al. · Journal of Biological Chemistry | 17 Jun 2014 | 88 |
| 49 | Saturated Boronic Acids, Boronates, and Trifluoroborates: An Update on Their Synthetic and Medicinal Chemistry Dmitriy M. Volochnyuk, Alina O. Gorlova, Oleksandr O. Grygorenko · Chemistry - A European Journal | 9 Sep 2021 | 83 |
| 50 | Recyclizations of 3-formylchromones with binucleophiles Andrey S. Plaskon, Oleksandr O. Grygorenko, Sergey V. Ryabukhin · Tetrahedron | 2 Feb 2012 | 83 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.