| 1 |
The histone mark H3K36me2 recruits DNMT3A and shapes the intergenic DNA methylation landscape
Daniel N. Weinberg et al. · Nature
Open access |
4 Sep 2019 |
572 |
| 2 |
Histone H1 loss drives lymphoma by disrupting 3D chromatin architecture
Nevin Yusufova et al. · Nature
Open access |
9 Dec 2020 |
274 |
| 3 |
Examining the Roles of H3K4 Methylation States with Systematically Characterized Antibodies
Rohan N. Shah, Adrian T. Grzybowski, Evan M. Cornett et al. · Molecular Cell
Open access |
20 Sep 2018 |
126 |
| 4 |
Complex-dependent histone acetyltransferase activity of KAT8 determines its role in transcription and cellular homeostasis
Aliaksandra Radzisheuskaya, Pavel V. Shliaha, Vasily V. Grinev et al. · Molecular Cell
Open access |
2 Mar 2021 |
119 |
| 5 |
A comparative analysis of cell surface targeting aptamers
Linsley Kelly, Keith E. Maier, Amy C. Yan et al. · Nature Communications
Open access |
Nov 2021 |
112 |
| 6 |
Characterization of the plant homeodomain (PHD) reader family for their histone tail interactions
Kanishk Jain, Caroline S. Fraser, Matthew R. Marunde et al. · Epigenetics & Chromatin
Open access |
24 Jan 2020 |
111 |
| 7 |
A chemical probe targeting the PWWP domain alters NSD2 nucleolar localization
David Dilworth et al. · Nature Chemical Biology
Open access |
15 Nov 2021 |
110 |
| 8 |
Two competing mechanisms of DNMT3A recruitment regulate the dynamics of de novo DNA methylation at PRC1-targeted CpG islands
Daniel N. Weinberg, Phillip Rosenbaum, Xiao Chen et al. · Nature Genetics
Open access |
13 May 2021 |
110 |
| 9 |
SETD5-Coordinated Chromatin Reprogramming Regulates Adaptive Resistance to Targeted Pancreatic Cancer Therapy
Zhentian Wang et al. · Cancer Cell
Open access |
21 May 2020 |
110 |
| 10 |
SMARCAL1 is a dual regulator of innate immune signaling and PD-L1 expression that promotes tumor immune evasion
Giuseppe Leuzzi et al. · Cell
Open access |
31 Jan 2024 |
105 |
| 11 |
Quantification of citrullinated histones: Development of an improved assay to reliably quantify nucleosomal H3Cit in human plasma
Charlotte Thålin et al. · Journal of Thrombosis and Haemostasis
Open access |
12 Jul 2020 |
95 |
| 12 |
Decoding the protein composition of whole nucleosomes with Nuc-MS
Luis F. Schachner, Kevin Jooß, Marc A. Morgan et al. · Nature Methods
Open access |
15 Feb 2021 |
70 |
| 13 |
Nucleosome conformation dictates the histone code
Matthew R. Marunde et al. · eLife
Open access |
6 Feb 2024 |
63 |
| 14 |
An acetylation-mediated chromatin switch governs H3K4 methylation read-write capability
Kanishk Jain et al. · eLife
Open access |
19 May 2023 |
61 |
| 15 |
Chromatin structure and its chemical modifications regulate the ubiquitin ligase substrate selectivity of UHRF1
Robert M. Vaughan, Bradley M. Dickson, Matthew F. Whelihan et al. · Proceedings of the National Academy of Sciences
Open access |
13 Aug 2018 |
59 |
| 16 |
Dysregulation of the histone demethylase KDM6B in alcohol dependence is associated with epigenetic regulation of inflammatory signaling pathways
Andrea L. Johnstone, Nadja S. Andrade, Estelle Barbier et al. · Addiction Biology
Open access |
Aug 2019 |
58 |
| 17 |
Structural basis of histone H2A lysine 119 deubiquitination by Polycomb repressive deubiquitinase BAP1/ASXL1
Jonathan F. Thomas et al. · Science Advances
Open access |
9 Aug 2023 |
54 |
| 18 |
A trivalent nucleosome interaction by PHIP/BRWD2 is disrupted in neurodevelopmental disorders and cancer
Marc A. Morgan, Irina K Popova, Anup Vaidya et al. · Genes & Development
Open access |
24 Nov 2021 |
45 |
| 19 |
Independent transcriptomic and proteomic regulation by type I and II protein arginine methyltransferases
Maxim I. Maron, Stephanie M. Lehman, Sitaram Gayatri et al. · iScience
Open access |
11 Aug 2021 |
43 |
| 20 |
Separation and Characterization of Endogenous Nucleosomes by Native Capillary Zone Electrophoresis–Top-Down Mass Spectrometry
Kevin Jooß, Luis F. Schachner, Rachel E. B. Watson et al. · Analytical Chemistry
Open access |
22 Mar 2021 |
43 |
| 21 |
Neutrophil Extracellular Trap Formation and Syndecan-1 Shedding Are Increased After Trauma
Julie Goswami, Taleen A. MacArthur, Kent R. Bailey et al. · Shock
Open access |
28 Jan 2021 |
34 |
| 22 |
A functional proteomics platform to reveal the sequence determinants of lysine methyltransferase substrate selectivity
Evan M. Cornett, Bradley M. Dickson, Krzysztof Krajewski et al. · Science Advances
Open access |
2 Nov 2018 |
32 |
| 23 |
Dinucleosome specificity and allosteric switch of the ISW1a ATP-dependent chromatin remodeler in transcription regulation
Saurabh K. Bhardwaj, Solomon G. Hailu, Lola Olufemi et al. · Nature Communications
Open access |
20 Nov 2020 |
30 |
| 24 |
Ubiquitinated histone H2B as gatekeeper of the nucleosome acidic patch
Chad W. Hicks, Sanim Rahman, Susan L. Gloor et al. · Nucleic Acids Research
Open access |
Aug 2024 |
27 |
| 25 |
Machine Learning to Quantitate Neutrophil NETosis
Laila Elsherif, Noah Sciaky, Carrington A. Metts et al. · Scientific Reports
Open access |
15 Nov 2019 |
27 |
| 26 |
Cancer-associated DNA hypermethylation of Polycomb targets requires DNMT3A dual recognition of histone H2AK119 ubiquitination and the nucleosome acidic patch
Kristjan H. Gretarsson et al. · Science Advances
Open access |
28 Aug 2024 |
26 |
| 27 |
SRCAP mutations drive clonal hematopoiesis through epigenetic and DNA repair dysregulation
Chun-Wei Chen et al. · Cell stem cell
Open access |
19 Oct 2023 |
26 |
| 28 |
The dCypher Approach to Interrogate Chromatin Reader Activity Against Posttranslational Modification-Defined Histone Peptides and Nucleosomes
Matthew R. Marunde, Irina K Popova, Ellen N Weinzapfel et al. · Methods in molecular biology
Book chapter |
2022 |
26 |
| 29 |
A ChIP-exo screen of 887 Protein Capture Reagents Program transcription factor antibodies in human cells
William Lai et al. · Genome Research
Open access |
23 Aug 2021 |
26 |
| 30 |
Beyond the tail: the consequence of context in histone post-translational modification and chromatin research
Ellen N Weinzapfel, Karlie N. Fedder-Semmes, Zu‐Wen Sun et al. · Biochemical Journal
Open access |
14 Feb 2024 |
24 |
| 31 |
Structural Insights into the Recognition of Mono- and Diacetylated Histones by the ATAD2B Bromodomain
Jonathan T. Lloyd, Kyle A. McLaughlin, Mulu Y. Lubula et al. · Journal of Medicinal Chemistry
Open access |
21 Oct 2020 |
24 |
| 32 |
Histone H3K18 & H3K23 acetylation directs establishment of MLL-mediated H3K4 methylation
Geoffrey Fox, Karl F. Poncha, B Rutledge Smith et al. · Journal of Biological Chemistry
Open access |
Jul 2024 |
23 |
| 33 |
Structure and flexibility of the yeast NuA4 histone acetyltransferase complex
Stefan A Zukin, Matthew R. Marunde, Irina K Popova et al. · eLife
Open access |
20 Oct 2022 |
21 |
| 34 |
EZH1 is an antipsychotic-sensitive epigenetic modulator of social and motivational behavior that is dysregulated in schizophrenia
Andrea L. Johnstone, Jiaqi J. O’Reilly, Annika J. Patel et al. · Neurobiology of Disease
Open access |
9 Aug 2018 |
18 |
| 35 |
NSD2 inhibitors rewire chromatin to treat lung and pancreatic cancers
Jinho Jeong et al. · Nature
Open access |
6 Aug 2025 |
14 |
| 36 |
A needed nomenclature for nucleosomes
Michael-Christopher Keogh et al. · Molecular Cell
Open access |
Oct 2025 |
13 |
| 37 |
DNASE-MEDIATED DISSOLUTION OF NEUTROPHIL EXTRACELLULAR TRAPS ACCELERATES IN VITRO THROMBIN GENERATION KINETICS IN TRAUMA PATIENTS
Julie Goswami, Taleen A. MacArthur, Cillian Richard Mahony et al. · Shock
Open access |
8 Aug 2022 |
13 |
| 38 |
Chromatin Immunoprecipitation (ChIP) to Study DNA–Protein Interactions
Eliza C. Small, Danielle N Maryanski, Keli L Rodriguez et al. · Methods in molecular biology
Book chapter |
2021 |
13 |
| 39 |
The SWI/SNF PBAF complex facilitates REST occupancy at repressive chromatin
Elena Grossi, Christie B. Nguyen, Saul Carcamo et al. · Molecular Cell
Open access |
18 Apr 2025 |
9 |
| 40 |
Multivalent binding of the tardigrade Dsup protein to chromatin promotes yeast survival and longevity upon exposure to oxidative damage
Rhiannon R. Aguilar et al. · Nature Communications
Open access |
29 Sep 2025 |
8 |
| 41 |
Single-molecule analysis of transcription activation: dynamics of SAGA coactivator recruitment
Jongcheol Jeon, Larry J. Friedman, Daniel J. Zhou et al. · Nature Structural & Molecular Biology
Open access |
14 Jan 2025 |
8 |
| 42 |
Multivalent binding of the tardigrade Dsup protein to chromatin promotes yeast survival and longevity upon exposure to oxidative damage
Jessica K. Tyler, Rhiannon R. Aguilar, Nina Arslanovic et al. · Research Square
PreprintOpen access |
28 Jul 2023 |
8 |
| 43 |
Nucleosome context regulates chromatin reader preference
Matthew R. Marunde et al. · Nucleic Acids Research
Open access |
Oct 2025 |
5 |
| 44 |
High-Efficiency Genomic Mapping of Chromatin-Associated Targets with CUT&RUN
Tessa M. Firestone et al. · Methods in molecular biology
Book chapterOpen access |
2026 |
4 |
| 45 |
Neuroinvasive flavivirus pathogenesis is restricted by host genetic factors in Collaborative Cross mice, independently of Oas1b
Brittany Jasperse, Melissa D. Mattocks, Kelsey M. Noll et al. · bioRxiv (Cold Spring Harbor Laboratory)
PreprintOpen access |
25 Oct 2022 |
4 |
| 46 |
Drosophila SUMM4 complex couples insulator function and DNA replication control
Evgeniya N. Andreyeva, Alexander V. Emelyanov, Markus Nevil et al. · eLife
Open access |
2 Dec 2022 |
3 |
| 47 |
Biomarkers of thromboinflammation correlate to COVID-19 infection and admission status in emergency department patients
Julie Goswami et al. · Thrombosis Update
Open access |
19 Nov 2021 |
3 |
| 48 |
Pharmacological targeting of a PWWP domain demonstrates cooperative control of NSD2 localization
David Dilworth et al. · bioRxiv (Cold Spring Harbor Laboratory)
PreprintOpen access |
7 Mar 2021 |
3 |
| 49 |
A ChIP-exo screen of 887 PCRP transcription factor antibodies in human cells
William K. M. Lai et al. · bioRxiv (Cold Spring Harbor Laboratory)
PreprintOpen access |
9 Jun 2020 |
3 |
| 50 |
Histone H3 N-terminal recognition by the PHD finger of PHRF1 is required for proper DNA damage response
Kanishk Jain, Pata-Eting Kougnassoukou Tchara, Abid Ali Khan et al. · Nucleic Acids Research
Open access |
8 Jul 2025 |
2 |