Science Explorer Back to mapMap

Most cited papers from EpiCypher (United States)

What are the most cited papers from EpiCypher (United States)?

The most cited paper from EpiCypher (United States) is "The histone mark H3K36me2 recruits DNMT3A and shapes the intergenic DNA methylation landscape" (Daniel N. Weinberg et al., 2019), with 572 citations. Next come "Histone H1 loss drives lymphoma by disrupting 3D chromatin architecture" (274) and "Examining the Roles of H3K4 Methylation States with Systematically Characterized Antibodies" (126).

Showing 50 of 76 papers. Every paper is listed.

Most cited papers, sortable by citations and release date
#Paper
1 The histone mark H3K36me2 recruits DNMT3A and shapes the intergenic DNA methylation landscape Daniel N. Weinberg et al. · Nature Open access 4 Sep 2019 572
2 Histone H1 loss drives lymphoma by disrupting 3D chromatin architecture Nevin Yusufova et al. · Nature Open access 9 Dec 2020 274
3 Examining the Roles of H3K4 Methylation States with Systematically Characterized Antibodies Rohan N. Shah, Adrian T. Grzybowski, Evan M. Cornett et al. · Molecular Cell Open access 20 Sep 2018 126
4 Complex-dependent histone acetyltransferase activity of KAT8 determines its role in transcription and cellular homeostasis Aliaksandra Radzisheuskaya, Pavel V. Shliaha, Vasily V. Grinev et al. · Molecular Cell Open access 2 Mar 2021 119
5 A comparative analysis of cell surface targeting aptamers Linsley Kelly, Keith E. Maier, Amy C. Yan et al. · Nature Communications Open access Nov 2021 112
6 Characterization of the plant homeodomain (PHD) reader family for their histone tail interactions Kanishk Jain, Caroline S. Fraser, Matthew R. Marunde et al. · Epigenetics & Chromatin Open access 24 Jan 2020 111
7 A chemical probe targeting the PWWP domain alters NSD2 nucleolar localization David Dilworth et al. · Nature Chemical Biology Open access 15 Nov 2021 110
8 Two competing mechanisms of DNMT3A recruitment regulate the dynamics of de novo DNA methylation at PRC1-targeted CpG islands Daniel N. Weinberg, Phillip Rosenbaum, Xiao Chen et al. · Nature Genetics Open access 13 May 2021 110
9 SETD5-Coordinated Chromatin Reprogramming Regulates Adaptive Resistance to Targeted Pancreatic Cancer Therapy Zhentian Wang et al. · Cancer Cell Open access 21 May 2020 110
10 SMARCAL1 is a dual regulator of innate immune signaling and PD-L1 expression that promotes tumor immune evasion Giuseppe Leuzzi et al. · Cell Open access 31 Jan 2024 105
11 Quantification of citrullinated histones: Development of an improved assay to reliably quantify nucleosomal H3Cit in human plasma Charlotte Thålin et al. · Journal of Thrombosis and Haemostasis Open access 12 Jul 2020 95
12 Decoding the protein composition of whole nucleosomes with Nuc-MS Luis F. Schachner, Kevin Jooß, Marc A. Morgan et al. · Nature Methods Open access 15 Feb 2021 70
13 Nucleosome conformation dictates the histone code Matthew R. Marunde et al. · eLife Open access 6 Feb 2024 63
14 An acetylation-mediated chromatin switch governs H3K4 methylation read-write capability Kanishk Jain et al. · eLife Open access 19 May 2023 61
15 Chromatin structure and its chemical modifications regulate the ubiquitin ligase substrate selectivity of UHRF1 Robert M. Vaughan, Bradley M. Dickson, Matthew F. Whelihan et al. · Proceedings of the National Academy of Sciences Open access 13 Aug 2018 59
16 Dysregulation of the histone demethylase KDM6B in alcohol dependence is associated with epigenetic regulation of inflammatory signaling pathways Andrea L. Johnstone, Nadja S. Andrade, Estelle Barbier et al. · Addiction Biology Open access Aug 2019 58
17 Structural basis of histone H2A lysine 119 deubiquitination by Polycomb repressive deubiquitinase BAP1/ASXL1 Jonathan F. Thomas et al. · Science Advances Open access 9 Aug 2023 54
18 A trivalent nucleosome interaction by PHIP/BRWD2 is disrupted in neurodevelopmental disorders and cancer Marc A. Morgan, Irina K Popova, Anup Vaidya et al. · Genes & Development Open access 24 Nov 2021 45
19 Independent transcriptomic and proteomic regulation by type I and II protein arginine methyltransferases Maxim I. Maron, Stephanie M. Lehman, Sitaram Gayatri et al. · iScience Open access 11 Aug 2021 43
20 Separation and Characterization of Endogenous Nucleosomes by Native Capillary Zone Electrophoresis–Top-Down Mass Spectrometry Kevin Jooß, Luis F. Schachner, Rachel E. B. Watson et al. · Analytical Chemistry Open access 22 Mar 2021 43
21 Neutrophil Extracellular Trap Formation and Syndecan-1 Shedding Are Increased After Trauma Julie Goswami, Taleen A. MacArthur, Kent R. Bailey et al. · Shock Open access 28 Jan 2021 34
22 A functional proteomics platform to reveal the sequence determinants of lysine methyltransferase substrate selectivity Evan M. Cornett, Bradley M. Dickson, Krzysztof Krajewski et al. · Science Advances Open access 2 Nov 2018 32
23 Dinucleosome specificity and allosteric switch of the ISW1a ATP-dependent chromatin remodeler in transcription regulation Saurabh K. Bhardwaj, Solomon G. Hailu, Lola Olufemi et al. · Nature Communications Open access 20 Nov 2020 30
24 Ubiquitinated histone H2B as gatekeeper of the nucleosome acidic patch Chad W. Hicks, Sanim Rahman, Susan L. Gloor et al. · Nucleic Acids Research Open access Aug 2024 27
25 Machine Learning to Quantitate Neutrophil NETosis Laila Elsherif, Noah Sciaky, Carrington A. Metts et al. · Scientific Reports Open access 15 Nov 2019 27
26 Cancer-associated DNA hypermethylation of Polycomb targets requires DNMT3A dual recognition of histone H2AK119 ubiquitination and the nucleosome acidic patch Kristjan H. Gretarsson et al. · Science Advances Open access 28 Aug 2024 26
27 SRCAP mutations drive clonal hematopoiesis through epigenetic and DNA repair dysregulation Chun-Wei Chen et al. · Cell stem cell Open access 19 Oct 2023 26
28 The dCypher Approach to Interrogate Chromatin Reader Activity Against Posttranslational Modification-Defined Histone Peptides and Nucleosomes Matthew R. Marunde, Irina K Popova, Ellen N Weinzapfel et al. · Methods in molecular biology Book chapter 2022 26
29 A ChIP-exo screen of 887 Protein Capture Reagents Program transcription factor antibodies in human cells William Lai et al. · Genome Research Open access 23 Aug 2021 26
30 Beyond the tail: the consequence of context in histone post-translational modification and chromatin research Ellen N Weinzapfel, Karlie N. Fedder-Semmes, Zu‐Wen Sun et al. · Biochemical Journal Open access 14 Feb 2024 24
31 Structural Insights into the Recognition of Mono- and Diacetylated Histones by the ATAD2B Bromodomain Jonathan T. Lloyd, Kyle A. McLaughlin, Mulu Y. Lubula et al. · Journal of Medicinal Chemistry Open access 21 Oct 2020 24
32 Histone H3K18 & H3K23 acetylation directs establishment of MLL-mediated H3K4 methylation Geoffrey Fox, Karl F. Poncha, B Rutledge Smith et al. · Journal of Biological Chemistry Open access Jul 2024 23
33 Structure and flexibility of the yeast NuA4 histone acetyltransferase complex Stefan A Zukin, Matthew R. Marunde, Irina K Popova et al. · eLife Open access 20 Oct 2022 21
34 EZH1 is an antipsychotic-sensitive epigenetic modulator of social and motivational behavior that is dysregulated in schizophrenia Andrea L. Johnstone, Jiaqi J. O’Reilly, Annika J. Patel et al. · Neurobiology of Disease Open access 9 Aug 2018 18
35 NSD2 inhibitors rewire chromatin to treat lung and pancreatic cancers Jinho Jeong et al. · Nature Open access 6 Aug 2025 14
36 A needed nomenclature for nucleosomes Michael-Christopher Keogh et al. · Molecular Cell Open access Oct 2025 13
37 DNASE-MEDIATED DISSOLUTION OF NEUTROPHIL EXTRACELLULAR TRAPS ACCELERATES IN VITRO THROMBIN GENERATION KINETICS IN TRAUMA PATIENTS Julie Goswami, Taleen A. MacArthur, Cillian Richard Mahony et al. · Shock Open access 8 Aug 2022 13
38 Chromatin Immunoprecipitation (ChIP) to Study DNA–Protein Interactions Eliza C. Small, Danielle N Maryanski, Keli L Rodriguez et al. · Methods in molecular biology Book chapter 2021 13
39 The SWI/SNF PBAF complex facilitates REST occupancy at repressive chromatin Elena Grossi, Christie B. Nguyen, Saul Carcamo et al. · Molecular Cell Open access 18 Apr 2025 9
40 Multivalent binding of the tardigrade Dsup protein to chromatin promotes yeast survival and longevity upon exposure to oxidative damage Rhiannon R. Aguilar et al. · Nature Communications Open access 29 Sep 2025 8
41 Single-molecule analysis of transcription activation: dynamics of SAGA coactivator recruitment Jongcheol Jeon, Larry J. Friedman, Daniel J. Zhou et al. · Nature Structural & Molecular Biology Open access 14 Jan 2025 8
42 Multivalent binding of the tardigrade Dsup protein to chromatin promotes yeast survival and longevity upon exposure to oxidative damage Jessica K. Tyler, Rhiannon R. Aguilar, Nina Arslanovic et al. · Research Square PreprintOpen access 28 Jul 2023 8
43 Nucleosome context regulates chromatin reader preference Matthew R. Marunde et al. · Nucleic Acids Research Open access Oct 2025 5
44 High-Efficiency Genomic Mapping of Chromatin-Associated Targets with CUT&RUN Tessa M. Firestone et al. · Methods in molecular biology Book chapterOpen access 2026 4
45 Neuroinvasive flavivirus pathogenesis is restricted by host genetic factors in Collaborative Cross mice, independently of Oas1b Brittany Jasperse, Melissa D. Mattocks, Kelsey M. Noll et al. · bioRxiv (Cold Spring Harbor Laboratory) PreprintOpen access 25 Oct 2022 4
46 Drosophila SUMM4 complex couples insulator function and DNA replication control Evgeniya N. Andreyeva, Alexander V. Emelyanov, Markus Nevil et al. · eLife Open access 2 Dec 2022 3
47 Biomarkers of thromboinflammation correlate to COVID-19 infection and admission status in emergency department patients Julie Goswami et al. · Thrombosis Update Open access 19 Nov 2021 3
48 Pharmacological targeting of a PWWP domain demonstrates cooperative control of NSD2 localization David Dilworth et al. · bioRxiv (Cold Spring Harbor Laboratory) PreprintOpen access 7 Mar 2021 3
49 A ChIP-exo screen of 887 PCRP transcription factor antibodies in human cells William K. M. Lai et al. · bioRxiv (Cold Spring Harbor Laboratory) PreprintOpen access 9 Jun 2020 3
50 Histone H3 N-terminal recognition by the PHD finger of PHRF1 is required for proper DNA damage response Kanishk Jain, Pata-Eting Kougnassoukou Tchara, Abid Ali Khan et al. · Nucleic Acids Research Open access 8 Jul 2025 2

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.