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Institution · Epix Pharmaceuticals (United States)

Most cited papers from Epix Pharmaceuticals (United States)

Epix Pharmaceuticals (United States)

What are the most cited papers from Epix Pharmaceuticals (United States)?

The most cited paper from Epix Pharmaceuticals (United States) is "Strategies for increasing the sensitivity of gadolinium based MRI contrast agents" (Peter D. Caravan, 2006), with 1,430 citations. Next come "Transfusion independence and HMGA2 activation after gene therapy of human β-thalassaemia" (1,285) and "A phase 2 study of two doses of bortezomib in relapsed or refractory myeloma" (745).

Showing 50 of 62 papers. Every paper with more than 61 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Strategies for increasing the sensitivity of gadolinium based MRI contrast agents Peter D. Caravan · Chemical Society Reviews Review 2006 1,430
2 Transfusion independence and HMGA2 activation after gene therapy of human β-thalassaemia Marina Cavazzana et al. · Nature Open access Sep 2010 1,285
3 A phase 2 study of two doses of bortezomib in relapsed or refractory myeloma Sundar Jagannath, Bart Barlogie, James R. Berenson et al. · British Journal of Haematology Oct 2004 745
4 Angiogenic synergism, vascular stability and improvement of hind-limb ischemia by a combination of PDGF-BB and FGF-2 Renhai Cao, Ebba Bråkenhielm, Robert Pawliuk et al. · Nature Medicine 31 Mar 2003 728
5 Tracer arrival timing‐insensitive technique for estimating flow in MR perfusion‐weighted imaging using singular value decomposition with a block‐circulant deconvolution matrix Ona Wu, Leif Østergaard, Robert M. Weisskoff et al. · Magnetic Resonance in Medicine 13 Jun 2003 607
6 GABA TRANSPORTER HETEROGENEITY: PHARMACOLOGY AND CELLULAR LOCALIZATION Laurence A. Borden · Neurochemistry International Oct 1996 592
7 Systematic exploration of essential yeast gene function with temperature-sensitive mutants Zhijian Li et al. · Nature Biotechnology Open access 27 Mar 2011 444
8 Performance comparison of a co-crystal of carbamazepine with marketed product Magali B. Hickey, Matthew L. Peterson, Lisa A. Scoppettuolo et al. · European Journal of Pharmaceutics and Biopharmaceutics 29 Dec 2006 388
9 Development of a large-scale chemogenomics database to improve drug candidate selection and to understand mechanisms of chemical toxicity and action Brigitte Ganter et al. · Journal of Biotechnology 12 Jul 2005 289
10 Drugs as materials: valuing physical form in drug discovery Colin R. Gardner, Christopher T. Walsh, Örn Almarsson · Nature Reviews Drug Discovery Review Nov 2004 282
11 Collagen‐Targeted MRI Contrast Agent for Molecular Imaging of Fibrosis Peter D. Caravan, Biplab Das, Stéphane Dumas et al. · Angewandte Chemie International Edition 25 Sep 2007 268
12 Preclinical Evaluation of the Pharmacokinetics, Biodistribution, and Elimination of MS-325, a Blood Pool Agent for Magnetic Resonance Imaging David J. Parmelee, Richard C. Walovitch, Hillori S. Ouellet et al. · Investigative Radiology Dec 1997 209
13 In Vitro Activity and Fecal Concentration of Rifaximin after Oral Administration Zhi‐Dong Jiang, Ke Shi, Ernesto Palazzini et al. · Antimicrobial Agents and Chemotherapy Open access Aug 2000 184
14 Postinfarction Myocardial Scarring in Mice: Molecular MR Imaging with Use of a Collagen-targeting Contrast Agent Patrick A. Helm, Peter D. Caravan, Brent A. French et al. · Radiology Open access 11 Apr 2008 184
15 The Cystic Fibrosis-causing Mutation ΔF508 Affects Multiple Steps in Cystic Fibrosis Transmembrane Conductance Regulator Biogenesis Patrick H. Thibodeau, John M. Richardson, Wei Wang et al. · Journal of Biological Chemistry Open access 29 Jul 2010 183
16 Do Cyclooxygenase-2 Inhibitors Provide Benefits Similar to Those of Traditional Nonsteroidal Anti-Inflammatory Drugs, with Less Gastrointestinal Toxicity? Mark L. Feldman, Alexander T. McMahon · Annals of Internal Medicine 18 Jan 2000 181
17 Antibacterial drug discovery: is it all downhill from here? Steven J. Projan, David M. Shlaes · Clinical Microbiology and Infection Open access 2004 171
18 Psychedelics and Other Psychoplastogens for Treating Mental Illness Maxemiliano V. Vargas, Retsina Meyer, Arabo A. Avanes et al. · Frontiers in Psychiatry Open access 4 Oct 2021 168
19 Thrombus Imaging With Fibrin-Specific Gadolinium-Based MR Contrast Agent EP-2104R Josef Vymazal, Elmar Spuentrup, Gerardo Cardenas-Molina et al. · Investigative Radiology 16 Oct 2009 168
20 A Phase I/II Clinical Trial of β‐Globin Gene Therapy for β‐Thalassemia Arthur Bank, Ronald Dorazio, Philippe Leboulch · Annals of the New York Academy of Sciences Nov 2005 167
21 High-Relaxivity Magnetic Resonance Imaging Contrast Agents Part 2 Vincent Jacques, Stéphane Dumas, Wei‐Chuan Sun et al. · Investigative Radiology Open access 31 Aug 2010 158
22 Molecular Magnetic Resonance Imaging of Coronary Thrombosis and Pulmonary Emboli With a Novel Fibrin-Targeted Contrast Agent Elmar Spuentrup, Arno Buecker, Marcus Katoh et al. · Circulation Mar 2005 153
23 Contrast agent-enhanced, free-breathing, three-dimensional coronary magnetic resonance angiography Matthias Stuber, René Michael Botnar, Peter G. Danias et al. · Journal of Magnetic Resonance Imaging Open access Nov 1999 151
24 [89Zr]Zr-girentuximab for PET–CT imaging of clear-cell renal cell carcinoma: a prospective, open-label, multicentre, phase 3 trial Brian M. Shuch et al. · The Lancet Oncology Open access 10 Sep 2024 150
25 An Integrated in Silico 3D Model-Driven Discovery of a Novel, Potent, and Selective Amidosulfonamide 5-HT1A Agonist (PRX-00023) for the Treatment of Anxiety and Depression Oren M. Becker, Dale S. Dhanoa, Yael Marantz et al. · Journal of Medicinal Chemistry Open access 9 May 2006 141
26 Effects of Tafamidis on Transthyretin Stabilization and Clinical Outcomes in Patients with Non-Val30Met Transthyretin Amyloidosis Giampaolo Merlini, Violaine Planté‐Bordeneuve, Daniel Philip Judge et al. · Journal of Cardiovascular Translational Research Open access 7 Oct 2013 141
27 A human β-cell line for transplantation therapy to control type 1 diabetes Michiki Narushima, Naoya Kobayashi, Teru Okitsu et al. · Nature Biotechnology 25 Sep 2005 139
28 Rectal Carcinoma: MRI with Histologic Correlation Before and After Chemoradiation Therapy Steven D Allen, Anwar R. Padhani, Andrzej S. K. Dzik-Jurasz et al. · American Journal of Roentgenology 22 Jan 2007 134
29 Monomeric Fc Fusions Jennifer A Dumont, Susan C. Low, Robert Peters et al. · BioDrugs 2006 129
30 Molecular Magnetic Resonance Imaging of Atrial Clots in a Swine Model Elmar Spuentrup, Bernd Fausten, Sylvia Kinzel et al. · Circulation Open access 12 Jul 2005 123
31 Classification of a large microarray data set: Algorithm comparison and analysis of drug signatures Georges Natsoulis, Laurent El Ghaoui, Gert R. G. Lanckriet et al. · Genome Research Open access May 2005 121
32 Amelioration of Experimental Autoimmune Myasthenia Gravis in Rats by Neonatal FcR Blockade Li Liu, Ana Maria Garcia, Helen Santoro et al. · The Journal of Immunology Apr 2007 121
33 Multilocus Binding Increases the Relaxivity of Protein‐Bound MRI Contrast Agents Zhaoda Zhang, Matthew T. Greenfield, Marga Spiller et al. · Angewandte Chemie International Edition 20 Sep 2005 111
34 Three‐dimensional MRI of coronary arteries using an intravascular contrast agent Debiao Li, Robert Dolan, Richard C. Walovitch et al. · Magnetic Resonance in Medicine Jun 1998 110
35 MR Angiography of Aortoiliac Occlusive Disease: A Phase III Study of the Safety and Effectiveness of the Blood-Pool Contrast Agent MS-325 Mathias Goyen, Mark Edelman, Pierre Perreault et al. · Radiology Sep 2005 107
36 TLR3 and Rig-Like Receptor on Myeloid Dendritic Cells and Rig-Like Receptor on Human NK Cells Are Both Mandatory for Production of IFN-γ in Response to Double-Stranded RNA Ivan Perrot, Florence Deauvieau, Catherine Massacrier et al. · The Journal of Immunology Open access 16 Jul 2010 105
37 Effects of tracer arrival time on flow estimates in MR perfusion‐weighted imaging Ona Wu, Leif Østergaard, Walter J. Koroshetz et al. · Magnetic Resonance in Medicine Open access 26 Sep 2003 103
38 High-Spatial-Resolution Multistation MR Angiography with Parallel Imaging and Blood Pool Contrast Agent: Initial Experience Konstantin Nikolaou, Harald Kramer, Christina Große et al. · Radiology Dec 2006 102
39 High Relaxivity Magnetic Resonance Imaging Contrast Agents Part 1 Stéphane Dumas, Vincent Jacques, Wei‐Chuan Sun et al. · Investigative Radiology Open access 31 Aug 2010 99
40 VRX-03011, a novel 5-HT4 agonist, enhances memory and hippocampal acetylcholine efflux Eric G. Mohler, Sharon Shacham, Silvia Noiman et al. · Neuropharmacology 2 Jul 2007 95
41 Treatment with methylnaltrexone is associated with increased survival in patients with advanced cancer Filip Janku, Lorraine Johnson, Daniel D. Karp et al. · Annals of Oncology Open access 30 Aug 2016 93
42 Ustekinumab: Lessons Learned from Targeting Interleukin‐12/23p40 in Immune‐Mediated Diseases Michael Rusty Elliott, Jacqueline Benson, MARION A. BLANK et al. · Annals of the New York Academy of Sciences Dec 2009 92
43 Novel inhibitors of poly(ADP-ribose) polymerase/PARP1 and PARP2 identified using a cell-based screen in yeast. Edward L. Perkins, Dongxu Sun, Anh Hoàng Nguyễn et al. · PubMed 15 May 2001 91
44 Small molecule correctors of F508del-CFTR discovered by structure-based virtual screening Ori Kalid, Martin Mense, Sharon Fischman et al. · Journal of Computer-Aided Molecular Design Open access 25 Oct 2010 89
45 Gadolinium Meets Medicinal Chemistry: MRI Contrast Agent Development Zhaoda Zhang, Shrikumar Nair, Thomas J. McMurry · Current Medicinal Chemistry 29 Mar 2005 86
46 Species Dependence on Plasma Protein Binding and Relaxivity of the Gadolinium-Based MRI Contrast Agent MS-325 Harriet Eldredge-Hindy, Marga Spiller, Jaclyn M. Chasse et al. · Investigative Radiology 15 Feb 2006 85
47 A Randomized, Multicenter Study Comparing the Safety and Efficacy of Sodium Phosphate Tablets With 2L Polyethylene Glycol Solution Plus Bisacodyl Tablets for Colon Cleansing John F. Johanson, John W. Popp, Lawrence B. Cohen et al. · The American Journal of Gastroenterology 16 Jun 2007 84
48 High-field pulsed EPR and ENDOR of Gd3+ complexes in glassy solutions Arnold M. Raitsimring, Andrei V. Astashkin, Oleg G. Poluektov et al. · Applied Magnetic Resonance Sep 2005 81
49 Modeling the 3D structure of GPCRs: advances and application to drug discovery. Oren M. Becker, Sharon Shacham, Yael Marantz et al. · PubMed May 2003 80
50 Blood pool agent strongly improves 3D magnetic resonance coronary angiography using an inversion pre-pulse Mark B.M. Hofman, Robert E. Henson, S�ndor J. Kov�cs et al. · Magnetic Resonance in Medicine Open access Feb 1999 78

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.