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Most cited papers from Epoch Biosciences (United States)

What are the most cited papers from Epoch Biosciences (United States)?

The most cited paper from Epoch Biosciences (United States) is "Quantitative Reverse Transcription–Polymerase Chain Reaction to Study mRNA Decay: Comparison of Endpoint and Real-Time Methods" (Thomas D. Schmittgen, Brian A. Zakrajsek, Alan Mills et al., 2000), with 1,049 citations. Next come "3'-Minor groove binder-DNA probes increase sequence specificity at PCR extension temperatures" (803) and "The RNA–DNA Hybrid Maintains the Register of Transcription by Preventing Backtracking of RNA Polymerase" (446).

Showing 50 of 60 papers. Every paper with more than 14 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Quantitative Reverse Transcription–Polymerase Chain Reaction to Study mRNA Decay: Comparison of Endpoint and Real-Time Methods Thomas D. Schmittgen, Brian A. Zakrajsek, Alan Mills et al. · Analytical Biochemistry Oct 2000 1,049
2 3'-Minor groove binder-DNA probes increase sequence specificity at PCR extension temperatures Igor V. Kutyavin · Nucleic Acids Research Open access 15 Jan 2000 803
3 The RNA–DNA Hybrid Maintains the Register of Transcription by Preventing Backtracking of RNA Polymerase Evgeny Nudler, Arkady A. MUSTAEV, Alex Goldfarb et al. · Cell Open access Apr 1997 446
4 Compute Trends Across Three Eras of Machine Learning Jaime Sevilla, Lennart Heim, Anson Ho et al. · 2022 International Joint Conference on Neural Networks (IJCNN) Conference paper 18 Jul 2022 311
5 DNA vector chemistry: The covalent attachment of signal peptides to plasmid DNA Magdolna G. Sebestyén, James J. Ludtke, Michael Cory Bassik et al. · Nature Biotechnology 1998 270
6 Efficient priming of PCR with short oligonucleotides conjugated to a minor groove binder Irina A. Afonina · Nucleic Acids Research Open access Jul 1997 208
7 The Role of Cyclooxygenase 2 in Ulcerative Colitis-Associated Neoplasia S. Nicholas Agoff, Teresa A. Brentnall, David A. Crispin et al. · American Journal Of Pathology Open access Sep 2000 169
8 Patient Perspectives on the Choice of Dialysis Modality: Results From the Empowering Patients on Choices for Renal Replacement Therapy (EPOCH-RRT) Study Claudia Dahlerus, Martha Quinn, Emily E. Messersmith et al. · American Journal of Kidney Diseases 26 Jun 2016 141
9 Minor Groove Binder-Conjugated DNA Probes for Quantitative DNA Detection by Hybridization-Triggered Fluorescence Irina A. Afonina, Michael W. Reed, Edward W. Lusby et al. · BioTechniques Open access Apr 2002 141
10 Atomic Force Microscopy Imaging of DNA Covalently Immobilized on a Functionalized Mica Substrate Luda S. Shlyakhtenko, Alexander A. Gall, Jeffrey J. Weimer et al. · Biophysical Journal Open access Jul 1999 132
11 Oligonucleotides Containing 2-Aminoadenine and 2-Thiothymine Act as Selectively Binding Complementary Agents Igor V. Kutyavin, Rebecca L. Rhinehart, Eugeny A. Lukhtanov et al. · Biochemistry 1996 126
12 Toward Transparent AI: A Survey on Interpreting the Inner Structures of Deep Neural Networks Tilman Räuker, Anson Ho, Stephen T. Casper et al. Conference paper Feb 2023 109
13 Software test automation Bradley S. Green · ACM SIGSOFT Software Engineering Notes Open access May 2000 95
14 Effects of Namaste Care on Residents Who Do Not Benefit From Usual Activities Joyce Simard, Ladislav Volicer · American Journal of Alzheimer s Disease & Other Dementias® Open access 30 Mar 2009 89
15 Effects of Pimobendan on Adverse Cardiac Events and Physical Activities in Patients With Mild to Moderate Chronic Heart Failure The EPOCH Study Group · Circulation Journal Open access 2002 85
16 Large scale probabilistic transient stability assessment using BC Hydro's on-line tool Ebrahim Vaahedi, W. Li, Timothy Kai-Loh Chia et al. · IEEE Transactions on Power Systems May 2000 78
17 Regional differences in the compaction of chromatin in human G0/G1 interphase nuclei Hiroki Yokota, M. J. Singer, Ger J. van den Engh et al. · Chromosome Research Apr 1997 74
18 Attachment of benzaldehyde-modified oligodeoxynucleotide probes to semicarbazide-coated glass Mikhail A. Podyminogin · Nucleic Acids Research Open access 15 Dec 2001 64
19 Application of GPR to a site investigation involving shallow faults Christopher L. Liner, Jeffrey L. Liner · The Leading Edge Nov 1997 63
20 G/C-modified oligodeoxynucleotides with selective complementarity: synthesis and hybridization properties Jinsuk Woo · Nucleic Acids Research Open access Jul 1996 60
21 Oligonucleotides with conjugated dihydropyrroloindole tripeptides: base composition and backbone effects on hybridization Igor V. Kutyavin, Evgeny A. LUKHTANOV, Howard Gamper et al. · Nucleic Acids Research Open access Sep 1997 52
22 Triplex targeting of a native gene in permeabilized intact cells: covalent modification of the gene for the chemokine receptor CCR5 Evgeniy Belousov · Nucleic Acids Research Open access Mar 1998 46
23 Neutral sphingomyelinase activation in endothelial and glial cell death induced by amyloid beta-peptide Ding‐I Yang, Chen-Hsiung Yeh, Shawei Chen et al. · Neurobiology of Disease Open access 5 Aug 2004 44
24 Reduced aggregation and improved specificity of G-rich oligodeoxyribonucleotides containing pyrazolo[3,4-d]pyrimidine guanine bases Igor V. Kutyavin · Nucleic Acids Research Open access 14 Nov 2002 40
25 Deadlines in Product Development Juanjuan Zhang · Management Science 4 Apr 2016 38
26 Rethinking insurgency: criminality, spirituality, and societal warfare in the Americas John P. Sullivan, Robert J. Bunker · Small Wars and Insurgencies 30 Nov 2011 37
27 Single nucleotide polymorphism genotyping by two colour melting curve analysis using the MGB Eclipse™ Probe System in challenging sequence environment Yevgeniy S. Belousov, Robert Alan Welch, Silvia Sanders et al. · Human Genomics Open access Mar 2004 36
28 Sensitive Detection Assays for Influenza RNA Do Not Reveal Viremia in US Blood Donors Susan L. Stramer, Cynthia S. Collins, Thomas Nugent et al. · The Journal of Infectious Diseases Open access 31 Jan 2012 35
29 Sequence-specific arrest of primer extension on single-stranded DNA by an oligonucleotide-minor groove binder conjugate. Irina A. Afonina, Igor V. Kutyavin, Evgeny A. LUKHTANOV et al. · Proceedings of the National Academy of Sciences Open access 16 Apr 1996 34
30 Improvement of long-term outcomes in pancreatic cancer and its associated factors within the gemcitabine era: a collaborative retrospective multicenter clinical review of 1,082 patients Taira Kuroda et al. · BMC Gastroenterology Open access 31 Aug 2013 33
31 Cyst of the choroid plexus of the left lateral ventricle. Luciano Andreussi, Alessandro Cama, C Cozzutto et al. · PubMed Jul 1979 33
32 Speleological and environmental history of Lida Ajer cave, western Sumatra Julien Louys, Mathieu Duval, Gilbert James Price et al. · Philosophical Transactions of the Royal Society B Biological Sciences Open access 7 Mar 2022 32
33 An improved real time PCR method for simultaneous detection of C282Y and H63D mutations in the HFE gene associated with hereditary hemochromatosis David K. Walburger, Irina A. Afonina, Robert Wydro · Mutation Research/Mutation Research Genomics 2001 31
34 Cenozoic Planktonic Biostratigraphy and Paleoceanography of the Tropical Western Indian Ocean E. Vincent · U.S. Government Printing Office eBooks Book chapterOpen access Oct 1974 30
35 Inhibition of Transcription Elongation in the HER-2/neu Coding Sequence by Triplex-Directed Covalent Modification of the Template Strand Scot Ebbinghaus, Henry Fortinberry, Howard Gamper · Biochemistry 17 Dec 1998 28
36 Recording point spread functions by wavefront modulation for interferenceless coded aperture correlation holography Xuelian Yu, Kangwei Wang, Junjun Xiao et al. · Optics Letters 19 Nov 2021 27
37 Rapid and Efficient Hybridization-Triggered Crosslinking Within a DNA Duplex by an Oligodeoxyribonucleotide Bearing a Conjugated Cyclopropapyrroloindole Evgeny A. LUKHTANOV, Mikhail A. Podyminogin, Igor V. Kutyavin et al. · Nucleic Acids Research Open access Feb 1996 27
38 Avatar-assisted therapy: a proof-of-concept pilot study of a novel technology-based intervention to treat substance use disorders Michael Solomon Gordon, Steven B. Carswell, Mary J. Schadegg et al. · The American Journal of Drug and Alcohol Abuse 17 Feb 2017 26
39 Expression pattern of mouse homolog of prostate‐specific membrane antigen (FOLH1) in the transgenic adenocarcinoma of the mouse prostate model Thomas D. Schmittgen, Brian A. Zakrajsek, Richard E. Hill et al. · The Prostate 18 Apr 2003 26
40 Antisense Oligonucleotides Containing Modified Bases Inhibit in Vitro Translation of Leishmania amazonensis mRNAs by Invading the Mini-exon Hairpin Daniel Compagno, Jed Noah Lampe, Chantal Bourget et al. · Journal of Biological Chemistry Open access Mar 1999 25
41 A study on energy saving rate for variable speed condition of multistage centrifugal pump Sang‐Ho Suh, Md Rakibuzzaman, Kyung‐Wuk Kim et al. · Journal of Thermal Science Nov 2015 24
42 Development of a multiplex real-time RT-PCR assay for detection of influenza A, influenza B, RSV and typing of the 2009-H1N1 influenza virus Weston C. Hymas, Alan Mills, Sheri Ferguson et al. · Journal of Virological Methods Apr 2010 23
43 Malaria prevalence defined by microscopy, antigen detection, DNA amplification and total nucleic acid amplification in a malaria‐endemic region during the peak malaria transmission season John Njenga Waitumbi, Jay Gerlach, Irina A. Afonina et al. · Tropical Medicine & International Health Open access 29 Mar 2011 22
44 Sequence-specific targeting and covalent modification of human genomic DNA Evgeniy Belousov · Nucleic Acids Research Open access Sep 1997 21
45 A zipper-action differential micro-mechanical tunable capacitor G.V. Ionis, Aleksander Dec, Kanako Suyama Conference paper 14 Nov 2002 21
46 Minor groove DNA alkylation directed by major groove triplex forming oligodeoxyribonucleotides Evgeny A. LUKHTANOV · Nucleic Acids Research Open access 15 Dec 1997 21
47 RecA-Catalyzed, Sequence-Specific Alkylation of DNA by Cross-Linking Oligonucleotides. Effects of Length and Nonhomologous Base Substitutions Mikhail A. Podyminogin, RICH B. JUN. MEYER, Howard Gamper · Biochemistry 1996 21
48 Carbon dots@metal–organic frameworks as dual-functional fluorescent sensors for Fe 3+ ions and nitro explosives Yufang Tao, Yansong Jiang, Yating Huang et al. · CrystEngComm 2021 20
49 Differential multi-finger MEMS tunable capacitors for RF integrated circuits G.V. Ionis, Aleksander Dec, Kanako Suyama Conference paper 25 Jun 2003 20
50 A 10 GHz frequency-drift temperature compensated LC VCO with fast-settling low-noise voltage regulator in 0.13 µm CMOS Hiroshi Akima, Aleksander Dec, Timothy B. Merkin et al. Conference paper Sep 2010 20

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.