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Sigma receptors: biology and therapeutic potential
Xavier Guitart, Xavier Codony, Xavier Monroy · Psychopharmacology
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9 Jun 2004 |
237 |
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A nested polymerase chain reaction (Ln-PCR) for diagnosing and monitoring Leishmania infantum infection in patients co-infected with human immunodeficiency virus
Israel Cruz, Carmen Cañavate, José Miguel Rubio et al. · Transactions of the Royal Society of Tropical Medicine and Hygiene
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Apr 2002 |
216 |
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Processing and characterization of plasticized PLA/PHB blends for biodegradable multiphase systems
Ilaria Armentano, Elena Fortunati, Nuria Burgos et al. · eXPRESS Polymer Letters
Open access |
2015 |
210 |
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Sigma-1 receptors regulate activity-induced spinal sensitization and neuropathic pain after peripheral nerve injury
Beatriz de la Puente, Xavier Nadal, Enrique F. Portillo-Salido et al. · Pain
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10 Jun 2009 |
170 |
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CD of proline‐rich polypeptides: Application to the study of the repetitive domain of maize glutelin‐2
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Synthesis and Characterization of Lactic Acid Oligomers: Evaluation of Performance as Poly(Lactic Acid) Plasticizers
Nuria Burgos, Daniel Tolaguera, Stefano Fiori et al. · Journal of Polymers and the Environment
Open access |
13 Nov 2013 |
162 |
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Sigma-1 receptors are essential for capsaicin-induced mechanical hypersensitivity: Studies with selective sigma-1 ligands and sigma-1 knockout mice
José Manuel Entrena, Enrique José Cobos, Francisco Rafael Nieto et al. · Pain
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18 Apr 2009 |
160 |
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The Nature of Intermolecular CuI⋅⋅⋅CuI Interactions: A Combined Theoretical and Structural Database Analysis
Maria Àngels Carvajal, Santiago Lopez Alvarez, Juan J. Novoa · Chemistry - A European Journal
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21 Apr 2004 |
153 |
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Medicinal chemistry strategies to 5-HT6 receptor ligands as potential cognitive enhancers and antiobesity agents
Jörg Holenz, Petrus J. Pauwels, José Luis Dı́az et al. · Drug Discovery Today
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Differential effects of various Ca2+ antagonists
A.J. Farre, Mario Colombo, Maria Fort et al. · General Pharmacology The Vascular System
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Tetrodotoxin inhibits the development and expression of neuropathic pain induced by paclitaxel in mice
Francisco Rafael Nieto, José Manuel Entrena, Cruz Miguel Cendán et al. · Pain
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150 |
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Co-crystal of Tramadol Hydrochloride–Celecoxib ( ctc ): A Novel API–API Co-crystal for the Treatment of Pain
Carmen Almansa, Ramon Mercè, Nicolas Tesson et al. · Crystal Growth & Design
Open access |
6 Mar 2017 |
148 |
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5-HT7 receptor activation inhibits mechanical hypersensitivity secondary to capsaicin sensitization in mice
Alex Brenchat, Luz I. Romero, Mónica Garcı́a et al. · Pain
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2 Jan 2009 |
144 |
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Formalin-induced pain is reduced in σ1 receptor knockout mice
Cruz Miguel Cendán, José M. Pujalte, Enrique F. Portillo-Salido et al. · European Journal of Pharmacology
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Mar 2005 |
139 |
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Synthesis and Biological Evaluation of the 1-Arylpyrazole Class of σ1 Receptor Antagonists: Identification of 4-{2-[5-Methyl-1-(naphthalen-2-yl)-1H-pyrazol-3-yloxy]ethyl}morpholine (S1RA, E-52862)
José Luis Dı́az, Rosa Cuberes, Joana Berrocal et al. · Journal of Medicinal Chemistry
Open access |
12 Jul 2012 |
130 |
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Efficacy of a Novel Sigma-1 Receptor Antagonist for Oxaliplatin-Induced Neuropathy: A Randomized, Double-Blind, Placebo-Controlled Phase IIa Clinical Trial
Jordi Bruna, Sebastián Videla, Andreas A. Argyriou et al. · Neurotherapeutics
Open access |
18 Sep 2017 |
123 |
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Particulate Matter from Electronic Cigarettes and Conventional Cigarettes: a Systematic Review and Observational Study
Esteve Fernández, Montse Ballbè, Xisca Sureda et al. · Current Environmental Health Reports
ReviewOpen access |
9 Oct 2015 |
122 |
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Trends in Sigma-1 Receptor Research: A 25-Year Bibliometric Analysis
Luz I. Romero, Enrique F. Portillo-Salido · Frontiers in Pharmacology
Open access |
24 May 2019 |
115 |
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Bio-based PLA_PHB plasticized blend films: Processing and structural characterization
Ilaria Armentano, Elena Fortunati, Nuria Burgos et al. · LWT
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19 Jun 2015 |
113 |
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Diabetes impairs endothelium-dependent relaxation of human penile vascular tissues mediated by NO and EDHF
Javier Angulo, Pedro Cuevas, Argentina Fernández et al. · Biochemical and Biophysical Research Communications
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23 Nov 2003 |
106 |
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Pharmacological activation of 5-HT7 receptors reduces nerve injury-induced mechanical and thermal hypersensitivity
Alex Brenchat, Xavier Nadal, Luz I. Romero et al. · Pain
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18 Apr 2010 |
104 |
| 22 |
Repurposing Sigma-1 Receptor Ligands for COVID-19 Therapy?
José Miguel Vela · Frontiers in Pharmacology
Open access |
9 Nov 2020 |
100 |
| 23 |
Functional Properties of Plasticized Bio-Based Poly(Lactic Acid)_Poly(Hydroxybutyrate) (PLA_PHB) Films for Active Food Packaging
Nuria Burgos, Ilaria Armentano, Elena Fortunati et al. · Food and Bioprocess Technology
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10 Jan 2017 |
98 |
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Grip strength in mice with joint inflammation: A rheumatology function test sensitive to pain and analgesia
Ángeles Montilla‐García, Miguel Angel Tejada, Gloria Perazzoli et al. · Neuropharmacology
Open access |
29 Jul 2017 |
96 |
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Medicinal Chemistry Driven Approaches Toward Novel and Selective Serotonin 5-HT6Receptor Ligands
Jörg Holenz, Ramon Mercè, José Luis Dı́az et al. · Journal of Medicinal Chemistry
Open access |
4 Sep 2004 |
96 |
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Biodegradable electrospun PLA-PHB fibers plasticized with oligomeric lactic acid
Marina P. Arrieta, M. Suarez Perdiguero, Stefano Fiori et al. · Polymer Degradation and Stability
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30 May 2020 |
90 |
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Chronic 5‐HT 6 receptor modulation by E‐6837 induces hypophagia and sustained weight loss in diet‐induced obese rats
Angels Fisas, Xavier Codony, Gonzalo Romero et al. · British Journal of Pharmacology
Open access |
19 Jun 2006 |
90 |
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Endocannabinoid control of glutamate NMDA receptors: the therapeutic potential and consequences of dysfunction
María del Rosario Rodríguez-Muñoz, Pilar Sánchez‐Blázquez, Manuel Merlos et al. · Oncotarget
Open access |
15 Jun 2016 |
89 |
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Antinociceptive effects of haloperidol and its metabolites in the formalin test in mice
Cruz Miguel Cendán, José M. Pujalte, Enrique F. Portillo-Salido et al. · Psychopharmacology
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Aug 2005 |
88 |
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Selective Sigma-1 (σ1) Receptor Antagonists: Emerging Target for the Treatment of Neuropathic Pain
José María López Díaz, Daniel Zamanillo, Jordi Corbera et al. · Central Nervous System Agents in Medicinal Chemistry
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Sep 2009 |
85 |
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Antioxidant Bilayers Based on PHBV and Plasticized Electrospun PLA-PHB Fibers Encapsulating Catechin
Marina P. Arrieta, Alberto Díez García, Daniel López et al. · Nanomaterials
Open access |
3 Mar 2019 |
82 |
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The σ1 Receptor Engages the Redox-Regulated HINT1 Protein to Bring Opioid Analgesia Under NMDA Receptor Negative Control
María del Rosario Rodríguez-Muñoz, Pilar Sánchez‐Blázquez, Raquel Herrero-Labrador et al. · Antioxidants and Redox Signaling
Open access |
4 Jan 2015 |
80 |
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Effectiveness of the MF59-adjuvanted influenza vaccine in preventing emergency admissions for pneumonia in the elderly over 64 years of age
Joan Puig‐Barberà, Javier Díez‐Domingo, Santiago Pérez‐Hoyos et al. · Vaccine
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13 Aug 2004 |
78 |
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“Bedside-to-Bench” Behavioral Outcomes in Animal Models of Pain: Beyond the Evaluation of Reflexes
Enrique J. Cobos, Enrique F. Portillo-Salido · Current Neuropharmacology
Open access |
Nov 2013 |
76 |
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The selective sigma-1 receptor antagonist E-52862 attenuates neuropathic pain of different aetiology in rats
Georgia Gris, Enrique F. Portillo-Salido, Bertrand Aubel et al. · Scientific Reports
Open access |
18 Apr 2016 |
75 |
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Potentiation of morphine-induced mechanical antinociception by σ1 receptor inhibition: Role of peripheral σ1 receptors
Cristina Sánchez–Fernández, Francisco Rafael Nieto, Rafael González‐Cano et al. · Neuropharmacology
Open access |
20 Mar 2013 |
71 |
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In Vitro Degradation of Plasticized PLA Electrospun Fiber Mats: Morphological, Thermal and Crystalline Evolution
Adrián Leonés, Laura Peponi, M. Lieblich et al. · Polymers
Open access |
13 Dec 2020 |
70 |
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Sigma‐1 receptors control neuropathic pain and macrophage infiltration into the dorsal root ganglion after peripheral nerve injury
Inmaculada Bravo‐Caparrós, M. Carmen Ruiz‐Cantero, Gloria Perazzoli et al. · The FASEB Journal
Open access |
10 Mar 2020 |
69 |
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Shape memory effect on electrospun PLA-based fibers tailoring their thermal response
Adrián Leonés, Águeda Sonseca, Daniel López et al. · European Polymer Journal
Open access |
10 May 2019 |
69 |
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Safety, tolerability and pharmacokinetics of single and multiple doses of a novel sigma‐1 receptor antagonist in three randomized phase I studies
Montserrat Abadías, Marisol Escriche, Anna Vaqué et al. · British Journal of Clinical Pharmacology
Open access |
21 May 2012 |
69 |
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Critical role of sigma-1 receptors in central neuropathic pain-related behaviours after mild spinal cord injury in mice
Sílvia Castany, Georgia Gris, José Miguel Vela et al. · Scientific Reports
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23 Feb 2018 |
68 |
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7-Azetidinylquinolones as antibacterial agents. Synthesis and structure-activity relationships
Jordi Frigola, J Parés, Jordi Corbera et al. · Journal of Medicinal Chemistry
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Opioid receptor signaling, analgesic and side effects induced by a computationally designed pH-dependent agonist
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6 Jun 2018 |
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Sigma 1 receptor as a therapeutic target for amyotrophic lateral sclerosis
Mireia Herrando‐Grabulosa, Núria Gaja‐Capdevila, José Miguel Vela et al. · British Journal of Pharmacology
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6 Aug 2020 |
63 |
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Sigma-1 Receptor and Pain
Manuel Merlos, Luz I. Romero, Daniel Zamanillo et al. · Handbook of experimental pharmacology
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Aspirin (ASA) regulates 5‐lipoxygenase activity and peroxisome proliferator‐activated receptor α‐mediated CINC‐1 release in rat liver cells: novel actions of lipoxin A 4 (LXA 4 ) and ASA‐triggered 15‐epi‐LXA 4
Anna Planagumà, Esther Titos, Marta López‐Parra et al. · The FASEB Journal
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The calcium-sensitive Sigma-1 receptor prevents cannabinoids from provoking glutamate NMDA receptor hypofunction: implications in antinociception and psychotic diseases
Pilar Sánchez‐Blázquez, María del Rosario Rodríguez-Muñoz, Raquel Herrero-Labrador et al. · The International Journal of Neuropsychopharmacology
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31 Jan 2014 |
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Immunohistochemical localization of the σ1-receptor in oligodendrocytes in the rat central nervous system
Gabriel Palacios, Asunción Muro, José Miguel Vela et al. · Brain Research
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Efficacy of selective 5‐HT6 receptor ligands determined by monitoring 5‐HT6 receptor‐mediated cAMP signaling pathways
Gonzalo Romero, Elisabeth Sánchez, Marta Pujol et al. · British Journal of Pharmacology
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24 Jul 2006 |
57 |