| 1 |
Functional Characterization of Human Receptors for Short Chain Fatty Acids and Their Role in Polymorphonuclear Cell Activation
Emmanuel Le Poul, Cécile Loison, Sofie Struyf et al. · Journal of Biological Chemistry
Open access |
Jul 2003 |
1,662 |
| 2 |
The Metastasis Suppressor Gene KiSS-1 Encodes Kisspeptins, the Natural Ligands of the Orphan G Protein-coupled Receptor GPR54
Masato Kotani, Michel Detheux, Ann L. Vandenbogaerde et al. · Journal of Biological Chemistry
Open access |
Sep 2001 |
1,552 |
| 3 |
Specific Recruitment of Antigen-presenting Cells by Chemerin, a Novel Processed Ligand from Human Inflammatory Fluids
Valérie Wittamer, Jean‐Denis Franssen, Marisa Vulcano et al. · The Journal of Experimental Medicine
Open access |
6 Oct 2003 |
890 |
| 4 |
Oxysterols direct immune cell migration via EBI2
Sébastien Hannedouche et al. · Nature
Open access |
Jul 2011 |
497 |
| 5 |
The onecut transcription factor HNF6 is required for normal development of the biliary tract
Frédéric Clotman, Vincent J. Lannoy, Michaël Reber et al. · Development
|
15 Apr 2002 |
375 |
| 6 |
Metabolite-Sensing Receptor Ffar2 Regulates Colonic Group 3 Innate Lymphoid Cells and Gut Immunity
Eunyoung Chun, Sydney Lavoie, Diogo Fonseca‐Pereira et al. · Immunity
Open access |
15 Oct 2019 |
340 |
| 7 |
Identification of a Novel Human ADP Receptor Coupled to Gi
Didier Communi, Nathalie Suarez Gonzalez, Michel Detheux et al. · Journal of Biological Chemistry
Open access |
Nov 2001 |
334 |
| 8 |
Chemerin expression marks early psoriatic skin lesions and correlates with plasmacytoid dendritic cell recruitment
Cristina Albanesi, Claudia Scarponi, Sabatino Pallotta et al. · The Journal of Experimental Medicine
Open access |
29 Dec 2008 |
329 |
| 9 |
Role of ChemR23 in directing the migration of myeloid and plasmacytoid dendritic cells to lymphoid organs and inflamed skin
William Vermi, Elena Riboldi, Valérie Wittamer et al. · The Journal of Experimental Medicine
Open access |
21 Feb 2005 |
290 |
| 10 |
Second Generation Assay for Thyrotropin Receptor Antibodies Has Superior Diagnostic Sensitivity for Graves’ Disease
Sabine Costagliola, Nils G. Morgenthaler, Rudolf Hoermann et al. · The Journal of Clinical Endocrinology & Metabolism
|
1999 |
261 |
| 11 |
Mouse ChemR23 Is Expressed in Dendritic Cell Subsets and Macrophages, and Mediates an Anti-Inflammatory Activity of Chemerin in a Lung Disease Model
Souphalone Luangsay, Valérie Wittamer, Benjamin Bondue et al. · The Journal of Immunology
|
20 Oct 2009 |
255 |
| 12 |
Real-Time Monitoring of Morphological Changes in Living Cells by Electronic Cell Sensor Arrays: An Approach To Study G Protein-Coupled Receptors
Naichen Yu, Josephine M. Atienza, Jérôme Bernard et al. · Analytical Chemistry
|
2 Dec 2005 |
237 |
| 13 |
Genetic Immunization Against the Human Thyrotropin Receptor Causes Thyroiditis and Allows Production of Monoclonal Antibodies Recognizing the Native Receptor
Sabine Costagliola, Patrice Rodien, M -C Many et al. · The Journal of Immunology
|
Feb 1998 |
211 |
| 14 |
The Second Extracellular Loop of CCR5 Is the Major Determinant of Ligand Specificity
Michel Samson, Gregory J. LaRosa, Frédérick Libert et al. · Journal of Biological Chemistry
Open access |
Oct 1997 |
181 |
| 15 |
The Orexin OX1 Receptor Activates a Novel Ca2+ Influx Pathway Necessary for Coupling to Phospholipase C
Per-Eric Lund, Ramin Shariatmadari, Ain Uustare et al. · Journal of Biological Chemistry
Open access |
Oct 2000 |
172 |
| 16 |
CD26/Dipeptidyl-Peptidase IV Down-Regulates the Eosinophil Chemotactic Potency, But Not the Anti-HIV Activity of Human Eotaxin by Affecting Its Interaction with CC Chemokine Receptor 3
Sofie Struyf, Paul Proost, Dominique Schols et al. · The Journal of Immunology
Open access |
Apr 1999 |
154 |
| 17 |
Pharmacological characterization of human NPFF1 and NPFF2 receptors expressed in CHO cells by using NPY Y1 receptor antagonists
Catherine Mollereau, Honoré Mazarguil, Delphine Marcus et al. · European Journal of Pharmacology
|
Sep 2002 |
147 |
| 18 |
Palmitoylation of CCR5 Is Critical for Receptor Trafficking and Efficient Activation of Intracellular Signaling Pathways
Cédric Blanpain, Valérie Wittamer, Jean-Marie Vanderwinden et al. · Journal of Biological Chemistry
Open access |
Jun 2001 |
143 |
| 19 |
Multiple Active States and Oligomerization of CCR5 Revealed by Functional Properties of Monoclonal Antibodies
Cédric Blanpain, Jean-Marie Vanderwinden, Josef Cihak et al. · Molecular Biology of the Cell
Open access |
Feb 2002 |
139 |
| 20 |
Natural Proteolytic Processing of Hemofiltrate Cc Chemokine 1 Generates a Potent Cc Chemokine Receptor (Ccr)1 and Ccr5 Agonist with Anti-HIV Properties
Michel Detheux, Ludger Ständker, Jalal Vakili et al. · The Journal of Experimental Medicine
Open access |
20 Nov 2000 |
138 |
| 21 |
Functional characterization of a human receptor for neuropeptide FF and related peptides
Masato Kotani, Catherine Mollereau, Michel Detheux et al. · British Journal of Pharmacology
Open access |
May 2001 |
135 |
| 22 |
Identification and characterization of an endogenous chemotactic ligand specific for FPRL2
Isabelle Migeotte, Elena Riboldi, Jean‐Denis Franssen et al. · The Journal of Experimental Medicine
Open access |
28 Dec 2004 |
122 |
| 23 |
Identification of Natural Ligands for the Orphan G Protein-coupled Receptors GPR7 and GPR8
Stéphane Brézillon, Vincent J. Lannoy, Jean-Denis Franssen et al. · Journal of Biological Chemistry
Open access |
2003 |
121 |
| 24 |
Extracellular Cysteines of CCR5 Are Required for Chemokine Binding, but Dispensable for HIV-1 Coreceptor Activity
Cédric Blanpain, Benhur Lee, Jalal Vakili et al. · Journal of Biological Chemistry
Open access |
Jul 1999 |
116 |
| 25 |
Vasopressin-like peptide and its receptor function in an indirect diuretic signaling pathway in the red flour beetle
Michael J. Aikins, David A. Schooley, Khurshida Begum et al. · Insect Biochemistry and Molecular Biology
|
11 May 2008 |
111 |
| 26 |
Expression of Free Fatty Acid Receptor 2 by Dendritic Cells Prevents Their Expression of Interleukin 27 and Is Required for Maintenance of Mucosal Barrier and Immune Response Against Colorectal Tumors in Mice
Sydney Lavoie, Eunyoung Chun, Sena Bae et al. · Gastroenterology
Open access |
7 Jan 2020 |
104 |
| 27 |
The Ajellomycetaceae, a new family of vertebrate-associated Onygenales
Wendy A. Untereiner, James Alexander Scott, Françoise A. Naveau et al. · Mycologia
|
Jul 2004 |
101 |
| 28 |
Identification of the C3a Receptor (C3AR1) as the Target of the VGF-derived Peptide TLQP-21 in Rodent Cells
Sébastien Hannedouche, Valérie Beck, Juliet R. Leighton-Davies et al. · Journal of Biological Chemistry
Open access |
12 Aug 2013 |
100 |
| 29 |
Adaptation of Aequorin Functional Assay to High Throughput Screening
Emmanuel Le Poul, Sunao Hisada, Yoshinori Mizuguchi et al. · SLAS DISCOVERY
Open access |
Feb 2002 |
99 |
| 30 |
Two Subtypes of Ecdysis-triggering Hormone Receptor inDrosophila melanogaster
Yoonseong Park, Young‐Joon Kim, Vincent Dupriez et al. · Journal of Biological Chemistry
Open access |
May 2003 |
95 |
| 31 |
ChemR23 Dampens Lung Inflammation and Enhances Anti-viral Immunity in a Mouse Model of Acute Viral Pneumonia
Benjamin Bondue, Olivier Vosters, Patricia de Nadaı̈ et al. · PLoS Pathogens
Open access |
3 Nov 2011 |
92 |
| 32 |
Activation of CCR5 by Chemokines Involves an Aromatic Cluster between Transmembrane Helices 2 and 3
Cédric Govaerts, Antoine Bondue, Jean–Yves Springael et al. · Journal of Biological Chemistry
Open access |
2003 |
87 |
| 33 |
Expression of P2Y receptors in cell lines derived from the human lung
Didier Communi, Pascale Paindavoine, Graham A. Place et al. · British Journal of Pharmacology
Open access |
May 1999 |
84 |
| 34 |
Formyl Peptide Receptor-Like 2 Is Expressed and Functional in Plasmacytoid Dendritic Cells, Tissue-Specific Macrophage Subpopulations, and Eosinophils
Thalie Devosse, Aude Guillabert, Nicky D’Haene et al. · The Journal of Immunology
Open access |
Apr 2009 |
80 |
| 35 |
Synthetic full-length and truncated RANTES inhibit HIV-1 infection of primary macrophages
Loyda Ylisastigui, Jean Vizzavona, Eugenia Drakopoulou et al. · AIDS
|
Sep 1998 |
80 |
| 36 |
The NK3 Receptor Antagonist ESN364 Suppresses Sex Hormones in Men and Women
Graeme L. Fraser, Steven Ramael, Hamid R. Hoveyda et al. · The Journal of Clinical Endocrinology & Metabolism
|
14 Dec 2015 |
79 |
| 37 |
Generation of a mouse monoclonal TSH receptor antibody with stimulating activity
Sabine Costagliola, Jean‐Denis Franssen, Marco Bonomi et al. · Biochemical and Biophysical Research Communications
Open access |
Dec 2002 |
79 |
| 38 |
The NK3 Receptor Antagonist ESN364 Interrupts Pulsatile LH Secretion and Moderates Levels of Ovarian Hormones Throughout the Menstrual Cycle
Graeme L. Fraser, Hamid R. Hoveyda, Iain James Clarke et al. · Endocrinology
|
25 Aug 2015 |
79 |
| 39 |
Production of bioactive amino‐terminal domain of the thyrotropin receptor via insertion in the plasma membrane by a glycosylphosphatidylinositol anchor
Sabine Costagliola, Daphne H C Khoo, Gilbert Vassart · FEBS Letters
|
9 Oct 1998 |
77 |
| 40 |
Characterization of binding, functional activity, and contractile responses of the selective 5‐HT1F receptor agonist lasmiditan
Eloísa Rubio‐Beltrán, Alejandro Labastida‐Ramírez, Kristian Agmund Haanes et al. · British Journal of Pharmacology
Open access |
16 Aug 2019 |
75 |
| 41 |
Activation of GPR54 promotes cell cycle arrest and apoptosis of human tumor cells through a specific transcriptional program not shared by other Gq-coupled receptors
Jérôme A. J. Becker, Jean‐François Mirjolet, Jérôme Bernard et al. · Biochemical and Biophysical Research Communications
|
16 Dec 2004 |
69 |
| 42 |
The Role of ChemR23 in the Induction and Resolution of Cigarette Smoke-Induced Inflammation
Tine Demoor, Ken R. Bracke, Lisa L Dupont et al. · The Journal of Immunology
Open access |
24 Mar 2011 |
66 |
| 43 |
Distribution and regulation of expression of the putative human chemokine receptor HCR in leukocyte populations
Isabelle Migeotte, Jean-Denis Franssen, Stanislas Goriely et al. · European Journal of Immunology
Open access |
Feb 2002 |
62 |
| 44 |
Agonist and antagonist activities on human NPFF2 receptors of the NPY ligands GR231118 and BIBP3226
Catherine Mollereau, Christine Gouardères, Yvan Dumont et al. · British Journal of Pharmacology
Open access |
May 2001 |
59 |
| 45 |
Optimization of Novel Antagonists to the Neurokinin-3 Receptor for the Treatment of Sex-Hormone Disorders (Part II)
Hamid R. Hoveyda, Graeme L. Fraser, Guillaume Dutheuil et al. · ACS Medicinal Chemistry Letters
Open access |
19 May 2015 |
59 |
| 46 |
ChemR23 knockout mice display mild obesity but no deficit in adipocyte differentiation
Laurie Rouger, R Denis, Souphalone Luangsay et al. · Journal of Endocrinology
Open access |
Oct 2013 |
56 |
| 47 |
Aequorin-Based Functional Assays for G-Protein-Coupled Receptors, Ion Channels, and Tyrosine Kinase Receptors
Vincent Dupriez, Karlien Maes, Emmanuel Le Poul et al. · Receptors and Channels
|
2002 |
54 |
| 48 |
Discovery and preliminary SARs of keto-indoles as novel indoleamine 2,3-dioxygenase (IDO) inhibitors
Eduard Dolušić, Pierre Larrieu, Sébastien Blanc et al. · European Journal of Medicinal Chemistry
Open access |
27 Feb 2011 |
54 |
| 49 |
Urokinase Plasminogen Activator and Plasmin Efficiently Convert Hemofiltrate CC Chemokine 1 into Its Active [9–74] Processed Variant
Jalal Vakili, Ludger Ständker, Michel Detheux et al. · The Journal of Immunology
Open access |
Sep 2001 |
52 |
| 50 |
Design and in vitro characterization of PAC1/VPAC1-selective agonists with potent neuroprotective effects
Ngoc‐Duc Doan, Steve Bourgault, Agnieszka Dejda et al. · Biochemical Pharmacology
|
30 Nov 2010 |
47 |