Most cited papers from Evotec (Germany)

Evotec (Germany)

What are the most cited papers from Evotec (Germany)?

The most cited paper from Evotec (Germany) is "Ionotropic and metabotropic glutamate receptor structure and pharmacology" (James N.C. Kew, John A. Kemp, 2005), with 788 citations. Next come "Diagnostic Value of Cerebrospinal Fluid Neurofilament Light Protein in Neurology" (785) and "NMDA receptor pathways as drug targets" (480).

Published TypeFieldAccessAuthorsCitations

Showing 50 of 60 papers. Every paper with more than 76 citations is listed.

Most cited papers, sortable by citations and release date
#	Paper
1	Ionotropic and metabotropic glutamate receptor structure and pharmacology James N.C. Kew, John A. Kemp · Psychopharmacology	24 Feb 2005	788
2	Diagnostic Value of Cerebrospinal Fluid Neurofilament Light Protein in Neurology Claire Bridel et al. · JAMA Neurology Open access	17 Jun 2019	785
3	NMDA receptor pathways as drug targets John A. Kemp, Ruth M. McKernan · Nature Neuroscience	28 Oct 2002	480
4	Integrated genomics and proteomics define huntingtin CAG length–dependent networks in mice Peter Langfelder et al. · Nature Neuroscience Open access	22 Feb 2016	463
5	Discovery of potent SOS1 inhibitors that block RAS activation via disruption of the RAS–SOS1 interaction Roman Christian Hillig et al. · Proceedings of the National Academy of Sciences Open access	25 Jan 2019	385
6	SARM1 is a metabolic sensor activated by an increased NMN/NAD+ ratio to trigger axon degeneration Matthew D. Figley et al. · Neuron Open access	2 Mar 2021	354
7	Dendritic Structural Degeneration Is Functionally Linked to Cellular Hyperexcitability in a Mouse Model of Alzheimer’s Disease Zuzana Šišková, Daniel Justus, Hiroshi Kaneko et al. · Neuron Open access	16 Nov 2014	345
8	Age-Dependent Neurodegeneration and Alzheimer-Amyloid Plaque Formation in Transgenic Drosophila Isabell Greeve, Doris Kretzschmar, Jakob-Andreas Tschäpe et al. · Journal of Neuroscience Open access	21 Apr 2004	294
9	MaxDIA enables library-based and library-free data-independent acquisition proteomics Pavel G. Sinitcyn, Hamid Hamzeiy, Favio Salinas Soto et al. · Nature Biotechnology Open access	8 Jul 2021	273
10	A study in male and female 5-HT transporter knockout rats: An animal model for anxiety and depression disorders Berend Olivier, Marieke G. C. van der Hart, Rachel P. L. van Swelm et al. · Neuroscience	2 Jan 2008	253
11	Small molecules inhibit the interaction of Nrf2 and the Keap1 Kelch domain through a non-covalent mechanism Douglas J. Marcotte et al. · Bioorganic & Medicinal Chemistry Open access	19 Apr 2013	243
12	A 3-D microelectrode system for handling and caging single cells and particles Torsten Müller, Gabriele Gradl, Steffen Howitz et al. · Biosensors and Bioelectronics	Mar 1999	242
13	Microdevices for manipulation and accumulation of micro‐ and nanoparticles by dielectrophoresis Manfried Dürr, Jörg Kentsch, Torsten Müller et al. · Electrophoresis	Feb 2003	239
14	Allele-selective transcriptional repression of mutant HTT for the treatment of Huntington’s disease Bryan Zeitler et al. · Nature Medicine	Jul 2019	224
15	Histone deacetylase 10 promotes autophagy-mediated cell survival Ina Oehme, Jan-Peter Linke, Barbara C. Böck et al. · Proceedings of the National Academy of Sciences Open access	25 Jun 2013	223
16	Glutamate- and GABA-based CNS therapeutics Alan C. Foster, John A. Kemp · Current Opinion in Pharmacology	23 Dec 2005	218
17	The role of C16:0 ceramide in the development of obesity and type 2 diabetes: CerS6 inhibition as a novel therapeutic approach Suryaprakash Raichur, Bodo Brunner, Maximilian Bielohuby et al. · Molecular Metabolism Open access	2 Jan 2019	200
18	MARK4 Is a Novel Microtubule-associated Proteins/Microtubule Affinity-regulating Kinase That Binds to the Cellular Microtubule Network and to Centrosomes Bernhard Trinczek, Miro Brajenovic, Andreas Ebneth et al. · Journal of Biological Chemistry Open access	Feb 2004	189
19	The histamine H3 receptor as a therapeutic drug target for CNS disorders Mark J. Gemkow, Adam J. Davenport, Silke Harich et al. · Drug Discovery Today	7 Mar 2009	182
20	Resveratrol as a Pan-HDAC Inhibitor Alters the Acetylation Status of Jistone Proteins in Human-Derived Hepatoblastoma Cells Sascha Venturelli, Alexander Berger, Alexander Böcker et al. · PLoS ONE Open access	30 Aug 2013	170
21	Analysis of High Accuracy, Quantitative Proteomics Data in the MaxQB Database Christoph Schaab, Tamar Geiger, Gabriele Stoehr et al. · Molecular & Cellular Proteomics Open access	2 Feb 2012	169
22	Therapeutic potential of NADPH oxidase 1/4 inhibitors Graciosa Quelhas Teixeira, Cédric Szyndralewiez, Sophie Molango et al. · British Journal of Pharmacology Open access	7 Jun 2016	165
23	Pharmacological SARM1 inhibition protects axon structure and function in paclitaxel-induced peripheral neuropathy Todd Bosanac, Robert O Hughes, Thomas M. Engber et al. · Brain Open access	6 May 2021	158
24	Consistent behavioral phenotype differences between inbred mouse strains in the IntelliCage Sven Krackow, Elisabetta Vannoni, Alina Codita et al. · Genes Brain & Behavior	2 Jun 2010	158
25	Structural basis of SARM1 activation, substrate recognition, and inhibition by small molecules Yun Yu Shi et al. · Molecular Cell Open access	24 Mar 2022	152
26	Time-resolved in vivo ubiquitinome profiling by DIA-MS reveals USP7 targets on a proteome-wide scale Martin Steger, Vadim Petrovich Demichev, Mattias Backman et al. · Nature Communications Open access	13 Sep 2021	150
27	Role of cannabis and endocannabinoids in the genesis of schizophrenia Emilio Fernández‐Espejo, María‐Paz Viveros, Luis Alfonso Font Núñez et al. · Psychopharmacology	23 Jul 2009	149
28	Miniaturized HTS technologies – uHTS Julian Wölcke, Dirk Ullmann · Drug Discovery Today	Jun 2001	148
29	Reduced function of the serotonin transporter is associated with decreased expression of BDNF in rodents as well as in humans Raffaella Molteni, Annamaria Cattaneo, Francesca Calabrese et al. · Neurobiology of Disease Open access	24 Dec 2009	132
30	The Ste20 Family Kinases MAP4K4, MINK1, and TNIK Converge to Regulate Stress-Induced JNK Signaling in Neurons Martin Larhammar, Sarah Huntwork‐Rodriguez, York Rudhard et al. · Journal of Neuroscience Open access	9 Oct 2017	130
31	NF-κB inducing kinase is a therapeutic target for systemic lupus erythematosus Hans D. Brightbill et al. · Nature Communications Open access	8 Jan 2018	128
32	Characterization of HTT Inclusion Size, Location, and Timing in the zQ175 Mouse Model of Huntington´s Disease: An In Vivo High-Content Imaging Study Nikisha Carty, Nadège Berson, Karsten Tillack et al. · PLoS ONE Open access	10 Apr 2015	128
33	Phosphodiesterase 10A Inhibition Improves Cortico-Basal Ganglia Function in Huntington’s Disease Models Vahri Beaumont et al. · Neuron Open access	Dec 2016	123
34	Phosphosignature Predicts Dasatinib Response in Non-small Cell Lung Cancer Martin Klammer, Marc Kaminski, Alexandra Zedler et al. · Molecular & Cellular Proteomics Open access	29 May 2012	122
35	Small-Animal PET Imaging of Amyloid-Beta Plaques with [11C]PiB and Its Multi-Modal Validation in an APP/PS1 Mouse Model of Alzheimer's Disease André Manook, Behrooz Hooshyar Yousefi, Antje Willuweit et al. · PLoS ONE Open access	9 Mar 2012	119
36	The tumor suppressor kinase DAPK3 drives tumor-intrinsic immunity through the STING–IFN-β pathway Mariko Takahashi, Chan‐Wang Jerry Lio, Anaamika Campeau et al. · Nature Immunology Open access	25 Mar 2021	115
37	Kaempferol, a new nutrition-derived pan-inhibitor of human histone deacetylases Alexander Berger, Sascha Venturelli, Mascha Kallnischkies et al. · The Journal of Nutritional Biochemistry	14 Nov 2012	115
38	Increased cell senescence in human metabolic disorders Rosa Spinelli, Ritesh Kumar Baboota, Silvia Gogg et al. · Journal of Clinical Investigation Open access	14 Jun 2023	114
39	AMPK activation protects from neuronal dysfunction and vulnerability across nematode, cellular and mouse models of Huntington's disease Rafael Pascual Vázquez-Manrique, Francesca Farina, Karine Cambon et al. · Human Molecular Genetics Open access	17 Dec 2015	114
40	Of mice and men: Pinpointing species differences in adipose tissue biology Emma Börgeson, Jérémie Boucher, Carolina E. Hagberg · Frontiers in Cell and Developmental Biology Open access	15 Sep 2022	109
41	Selective LRRK2 kinase inhibition reduces phosphorylation of endogenous Rab10 and Rab12 in human peripheral mononuclear blood cells Kenneth Thirstrup, Justus C. Dächsel, Felix S. Oppermann et al. · Scientific Reports Open access	25 Aug 2017	108
42	Plants Release Precursors of Histone Deacetylase Inhibitors to Suppress Growth of Competitors Sascha Venturelli, Regina G. Belz, Andreas Kämper et al. · The Plant Cell Open access	Nov 2015	108
43	Highly sensitive fluorescence detection technology currently available for HTS Christian Eggeling, Leif Brand, Dirk Ullmann et al. · Drug Discovery Today	Jul 2003	108
44	Prospective Isolation and Characterization of Genetically and Functionally Distinct AML Subclones Bauke de Boer, Janine C. M. Prick, Maurien G. M. Pruis et al. · Cancer Cell Open access	20 Sep 2018	107
45	Statistical accuracy in fluorescence fluctuation experiments Peet Kask, Roman Günther, Peter Axhausen · European Biophysics Journal	27 Jan 1997	105
46	Discovery of GluN2A-Selective NMDA Receptor Positive Allosteric Modulators (PAMs): Tuning Deactivation Kinetics via Structure-Based Design Matthew Volgraf et al. · Journal of Medicinal Chemistry Open access	26 Feb 2016	104
47	The potential of dielectrophoresis for single-cell experiments Torsten Müller, Annette Pfennig, Petra Klein et al. · IEEE Engineering in Medicine and Biology Magazine	Nov 2003	104
48	Mps1 Regulates Kinetochore-Microtubule Attachment Stability via the Ska Complex to Ensure Error-Free Chromosome Segregation John Maciejowski, Hauke Drechsler, Kathrin Grundner‐Culemann et al. · Developmental Cell Open access	Apr 2017	100
49	Stimulation of the metabotropic glutamate 2/3 receptor attenuates social novelty discrimination deficits induced by neonatal phencyclidine treatment Silke Harich, Gerhard Groß, Anton Bespalov · Psychopharmacology	22 Feb 2007	100
50	High-resolution snapshots of human N-myristoyltransferase in action illuminate a mechanism promoting N-terminal Lys and Gly myristoylation Cyril Dian, Inmaculada Pérez‐Dorado, Frédéric Rivière et al. · Nature Communications Open access	28 Feb 2020	92

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.