| 1 |
8-Hydroxy-2-(di-n-propylamino)-tetralin discriminates between subtypes of the 5-HT1 recognition site
Derek N. Middlemiss, John R. Fozard · European Journal of Pharmacology
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May 1983 |
869 |
| 2 |
Charge transport and mobility engineering in two-dimensional transition metal chalcogenide semiconductors
Songlin Li, Kazuhito Tsukagoshi, Emanuele Orgiu et al. · Chemical Society Reviews
ReviewOpen access |
23 Nov 2015 |
553 |
| 3 |
γ‐VINYL GABA (4‐amino‐hex‐5‐enoic acid), A NEW SELECTIVE IRREVERSIBLE INHIBITOR OF GABA‐T: EFFECTS ON BRAIN GABA METABOLISM IN MICE1
Michael J. Jung, Bruce J. Lippert, Brian W. Metcalf et al. · Journal of Neurochemistry
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Nov 1977 |
481 |
| 4 |
Anti-proliferative properties of DL-α-difluoromethyl ornithine in cultured cells. A consequence of the irreversible inhibition of ornithine decarboxylase
Pierre S. Mamont, Marie-Christine Duchesne, Jeffrey Grove et al. · Biochemical and Biophysical Research Communications
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Mar 1978 |
401 |
| 5 |
4‐Amino‐hex‐5‐enoic Acid, a Selective Catalytic Inhibitor of 4‐Aminobutyric‐Acid Aminotransferase in Mammalian Brain
Bruce J. Lippert, Brian W. Metcalf, Michel J. Jung et al. · European Journal of Biochemistry
Open access |
Apr 1977 |
378 |
| 6 |
High-performance liquid chromatographic procedure for the simultaneous determination of the natural polyamines and their monoacetyl derivatives
Nikolaus Seiler, Bernd Knödgen · Journal of Chromatography B Biomedical Sciences and Applications
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Dec 1980 |
314 |
| 7 |
From Hydrated Ni 3 (OH) 2 (C 8 H 4 O 4 ) 2 (H 2 O) 4 to Anhydrous Ni 2 (OH) 2 (C 8 H 4 O 4 ): Impact of Structural Transformations on Magnetic Properties
Adel Mesbah, Pierre Rabu, Romain Sibille et al. · Inorganic Chemistry
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8 Jan 2014 |
296 |
| 8 |
The Future of Layer-by-Layer Assembly: A Tribute to ACS Nano Associate Editor Helmuth Mohwald
Shuang Zhao et al. · ACS Nano
Open access |
24 May 2019 |
284 |
| 9 |
L-Ornithine Decarboxylase: an Essential Role in Early Mammalian Embryogenesis
John R. Fozard, Marie‐Louise Part, Nellikunja J. Prakash et al. · Science
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2 May 1980 |
245 |
| 10 |
Modification of Enzyme Activity by Vibrational Strong Coupling of Water
Robrecht M. A. Vergauwe, Anoop Thomas, Kalaivanan Nagarajan et al. · Angewandte Chemie International Edition
Open access |
26 Aug 2019 |
241 |
| 11 |
Platelet Aggregation induced by Arachidonic Acid is accompanied by Release of Potential Inflammatory Mediators distinct from PGE2 and PGF2
Bernardo Boris Vargaftig, P. Zirinis · Nature New Biology
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Jul 1973 |
227 |
| 12 |
THE EFFECT OF 4‐AMINO HEX‐5‐YNOIC ACID (γ‐ACETYLENIC GABA, γ‐ETHYNYL GABA) A CATALYTIC INHIBITOR OF GABA TRANSAMINASE, ON BRAIN GABA METABOLISM IN VIVO
Michael J. Jung, Bruce J. Lippert, Brian W. Metcalf et al. · Journal of Neurochemistry
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Apr 1977 |
217 |
| 13 |
Alpha-methyl ornithine, a potent competitive inhibitor of ornithine decarboxylase, blocks proliferation of rat hepatoma cells in culture.
Pierre S. Mamont, Peter Böhlen, Peter P. McCann et al. · Proceedings of the National Academy of Sciences
Open access |
May 1976 |
213 |
| 14 |
Audiogenic seizure protection by elevated brain GABA concentration in mice: Effects of γ-acetylenic GABA and γ-vinyl GABA, two irreversible GABA-T inhibitors
Paul J. Schechter, Yvette Tranier, M. Jung et al. · European Journal of Pharmacology
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Oct 1977 |
202 |
| 15 |
Self‐Defensive Biomaterial Coating Against Bacteria and Yeasts: Polysaccharide Multilayer Film with Embedded Antimicrobial Peptide
Gwenaëlle Cado, Rizwan Aslam, Lydie Séon et al. · Advanced Functional Materials
Open access |
16 Apr 2013 |
192 |
| 16 |
The relationship between GABA concentrations in brain and cerebrospinal fluid
Peter Böhlen, Sylvie Huot, Michael G. Palfreyman · Brain Research
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May 1979 |
188 |
| 17 |
Hierarchical functional gradients of pH-responsive self-assembled monolayers using dynamic covalent chemistry on surfaces
Lara Tauk, A. Schröder, Gero Decher et al. · Nature Chemistry
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23 Oct 2009 |
187 |
| 18 |
Mechanism of the Hypotensive Effect of Ketanserin
John R. Fozard · Journal of Cardiovascular Pharmacology
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Sep 1982 |
180 |
| 19 |
Acetylderivatives as intermediates in polyamine catabolism
Frank N. Bolkenius, Nikolaus Seiler · International Journal of Biochemistry
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1981 |
177 |
| 20 |
Inhibitors of GABA metabolism
Brian W. Metcalf · Biochemical Pharmacology
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Jun 1979 |
171 |
| 21 |
Greatly Enhanced Pressor Response to Antidiuretic Hormone in Patients with Impaired Cardiovascular Reflexes Due to Idiopathic Orthostatic Hypotension
Jan Möhring, K Glänzer, Jayme Antunes Maciel et al. · Journal of Cardiovascular Pharmacology
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Jul 1980 |
163 |
| 22 |
Polyelectrolyte Multilayers: A Versatile Tool for Preparing Antimicrobial Coatings
Lydie Séon, Philippe Lavall�e, Pierre Schaaf et al. · Langmuir
Open access |
29 Oct 2015 |
161 |
| 23 |
There is still plenty of room for layer-by-layer assembly for constructing nanoarchitectonics-based materials and devices
Katsuhiko Ariga, Yuri Lvov, Gero Decher · Physical Chemistry Chemical Physics
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2 Dec 2021 |
152 |
| 24 |
Spray‐Assisted Polyelectrolyte Multilayer Buildup: from Step‐by‐Step to Single‐Step Polyelectrolyte Film Constructions
Pierre Schaaf, Jean‐Claude Voegel, Loı̈c Jierry et al. · Advanced Materials
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26 Jan 2012 |
147 |
| 25 |
Assessment of ?Ca2+-antagonist? effects of drugs in K+-depolarized smooth muscle
Michael Spedding · Naunyn-Schmiedeberg s Archives of Pharmacology
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1982 |
143 |
| 26 |
On the Benefits of Rubbing Salt in the Cut: Self‐Healing of Saloplastic PAA/PAH Compact Polyelectrolyte Complexes
Andreas Reisch, Emilie Roger, Thida Phoeung et al. · Advanced Materials
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29 Jan 2014 |
139 |
| 27 |
Importance of Protein Binding for the Interpretation of Serum or Plasma Drug Concentrations
David J. Greenblatt, Edward M. Sellers, Jan Koch‐Weser · The Journal of Clinical Pharmacology
Open access |
6 May 1982 |
138 |
| 28 |
Catalytic inhibition of γ-aminobutyric acid-α-ketoglutarate transaminase of bacterial origin by 4-aminohex-5-ynoic acid, a substrate analog
Michel J. Jung, Brian W. Metcalf · Biochemical and Biophysical Research Communications
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Nov 1975 |
136 |
| 29 |
Automated fluorometric amino acid analysis: The determination of proline and hydroxyproline
Peter Böhlen, Michel Mellet · Analytical Biochemistry
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Apr 1979 |
134 |
| 30 |
8-Hydroxy-2-(di-n-propylamino) tetralin is devoid of activity at the 5-hydroxytryptamine autoreceptor in rat brain. Implications for the proposed link between the autoreceptor and the [3H] 5-HT recognition site
Derek N. Middlemiss · Naunyn-Schmiedeberg s Archives of Pharmacology
|
1984 |
132 |
| 31 |
Calcium Ions Promote Formation of Amyloid β-Peptide (1–40) Oligomers Causally Implicated in Neuronal Toxicity of Alzheimer's Disease
Anna Itkin, Vincent Duprès, Yves F. Dufrêne et al. · PLoS ONE
Open access |
28 Mar 2011 |
131 |
| 32 |
The ambiguity of adverse drug reactions
Jan Koch‐Weser, Edward M. Sellers, Rudolf Zacest · European Journal of Clinical Pharmacology
|
1977 |
130 |
| 33 |
Determination of DOPA, dopamine, DOPAC, epinephrine, norepinephrine, α-monofluoromethyldopa and α-difluoromethyldopa in various tissues of mice and rats using reversed-phase ion-pair liquid chromatography with electrochemical detection
Joseph E. Wagner, Michael G. Palfreyman, Monique M. Zraika · Journal of Chromatography B Biomedical Sciences and Applications
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Sep 1979 |
122 |
| 34 |
Increased gamma-aminobutyric acid (GABA), homocarnosine and β-alanine in cerebrospinal fluid of patients treated with γ-vinyl GABA (4-amino-hex-5-enoic acid)
Jeffrey Grove, Paul J. Schechter, Guy Tell et al. · Life Sciences
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May 1981 |
119 |
| 35 |
The pharmacology of GABA-transaminase inhibitors
Michael G. Palfreyman, Paul J. Schechter, W. R. Buckett et al. · Biochemical Pharmacology
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Apr 1981 |
117 |
| 36 |
Inhibition of EMT6 tumor growth by interference with polyamine biosynthesis ; Effects of α-difluoromethyl- ornithine, an irreversible inhibitor or ornithine decarboxylase
Nellikunja J. Prakash, Paul J. Schechter, Pierre S. Mamont et al. · Life Sciences
|
1980 |
116 |
| 37 |
Bretylium
Jan Koch‐Weser · New England Journal of Medicine
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Mar 1979 |
114 |
| 38 |
Effect of α-difluoromethylornithine, an enzyme-activated irreversible inhibitor of ornithine decarboxylase, on polyamine levels in rat tissues
Charles Danzin, Michel J. Jung, Jeffrey Grove et al. · Life Sciences
|
Feb 1979 |
114 |
| 39 |
Membrane Interactions of the Amphipathic Amino Terminus of Huntingtin
Matthias Michalek, Evgeniy Sergeevich Salnikov, Sebastiaan Werten et al. · Biochemistry
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10 Jan 2013 |
113 |
| 40 |
Effect of n‐dipropylacetate on amino acid concentrations in mouse brain: correlations with anti‐convulsant activity
Paul J. Schechter, Yvette Tranier, Jeffrey Grove · Journal of Neurochemistry
|
Nov 1978 |
109 |
| 41 |
Efficient Gas and Water Vapor Barrier Properties of Thin Poly(lactic acid) Packaging Films: Functionalization with Moisture Resistant Nafion and Clay Multilayers
Federico Carosio, Samuele Colonna, Alberto Fina et al. · Chemistry of Materials
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26 Sep 2014 |
108 |
| 42 |
Absorption and Disposition of Chlordiazepoxide in Young and Elderly Male Volunteers
Richard I. Shader, David J. Greenblatt, Jerold S. Harmatz et al. · The Journal of Clinical Pharmacology
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12 Nov 1977 |
107 |
| 43 |
Self-assembly of a neutral platinum( ii ) complex into highly emitting microcrystalline fibers through metallophilic interactions
Matteo Mauro, Alessandro Aliprandi, Cristina Cebrián et al. · Chemical Communications
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2014 |
106 |
| 44 |
Metabolic inhibitors and subcellular distribution of GABA
Shakir SARHAN, Nikolaus Seiler · Journal of Neuroscience Research
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1979 |
105 |
| 45 |
Biphasic induction of ornithine decarboxylase and putrescine levels in growing HTC cells
Peter P. McCann, Chantal Tardif, Pierre S. Mamont et al. · Biochemical and Biophysical Research Communications
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May 1975 |
104 |
| 46 |
Regulation of ornithine decarboxylase by ODC-antizyme in HTC cells
Peter P. McCann, Chantal Tardif, Pierre S. Mamont · Biochemical and Biophysical Research Communications
|
Apr 1977 |
101 |
| 47 |
Effects of acutely and chronically administered antidepressants on the clonidine-induced decrease in rat brain 3-methoxy-4-hydroxyphenylethylene-glycol sulphate content.
Michael F. Sugrue · Life Sciences
|
1981 |
99 |
| 48 |
Enzyme-activated irreversible inhibitors of L-ornithine:2-oxoacid aminotransferase. Demonstration of mechanistic features of the inhibition of ornithine aminotransferase by 4-aminohex-5-ynoic acid and gabaculine and correlation with in vivo activity.
Michael J. Jung, Nikolaus Seiler · Journal of Biological Chemistry
Open access |
Oct 1978 |
97 |
| 49 |
Effects of terfenadine and diphenhydramine alone or in combination with diazepam or alcohol on psychomotor performance and subjective feelings
L Moser, K. J. H�ther, Jan Koch‐Weser et al. · European Journal of Clinical Pharmacology
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1978 |
95 |
| 50 |
Polyamine metabolism and function in brain
Nikolaus Seiler · Neurochemistry International
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1981 |
93 |