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Institution · Gene Bridges (Germany)

Most cited papers from Gene Bridges (Germany)

What are the most cited papers from Gene Bridges (Germany)?

The most cited paper from Gene Bridges (Germany) is "EV-TRACK: transparent reporting and centralizing knowledge in extracellular vesicle research" (Jan Van Deun et al., 2017), with 1,345 citations. Next come "BAC TransgeneOmics: a high-throughput method for exploration of protein function in mammals" (637) and "Full-length RecE enhances linear-linear homologous recombination and facilitates direct cloning for bioprospecting" (454).

Showing 50 of 85 papers. Every paper is listed.

Most cited papers, sortable by citations and release date
#Paper
1 EV-TRACK: transparent reporting and centralizing knowledge in extracellular vesicle research Jan Van Deun et al. · Nature Methods 28 Feb 2017 1,345
2 BAC TransgeneOmics: a high-throughput method for exploration of protein function in mammals Ina Poser et al. · Nature Methods Open access 6 Apr 2008 637
3 Full-length RecE enhances linear-linear homologous recombination and facilitates direct cloning for bioprospecting Jun Fu, Xiaoying Bian, Shengbaio Hu et al. · Nature Biotechnology 29 Apr 2012 454
4 Techniques: Recombinogenic engineering–new options for cloning and manipulating DNA Joep P. P. Muyrers, Youming Zhang, Adrian Francis Stewart · Trends in Biochemical Sciences Review May 2001 259
5 Novel expression hosts for complex secondary metabolite megasynthetases: Production of myxochromide in the thermopilic isolate Corallococcus macrosporus GT-2 Olena Perlova, Klaus Gerth, Silvia Kuhlmann et al. · Microbial Cell Factories Open access 6 Jan 2009 252
6 Involvement of G-quadruplex regions in mammalian replication origin activity Paulina Prorok, Marie Artufel, Antoine Aze et al. · Nature Communications Open access 22 Jul 2019 207
7 A recombineering pipeline for functional genomics applied to Caenorhabditis elegans Mihail Sarov, Susan M. Schneider, Andrei Pozniakovski et al. · Nature Methods Open access 21 Sep 2006 206
8 Heterologous Expression of a Myxobacterial Natural Products Assembly Line in Pseudomonads via Red/ET Recombineering Silke C. Wenzel, Frank B. Gross, Youming Zhang et al. · Chemistry & Biology Open access Mar 2005 183
9 Successful engraftment of gene-corrected hematopoietic stem cells in non-conditioned patients with Fanconi anemia Paula Rı́o et al. · Nature Medicine Sep 2019 180
10 Myelodysplastic syndrome unrelated to lentiviral vector in a patient treated with gene therapy for sickle cell disease Matthew M. Hsieh, Melissa A. Bonner, Francis John Pierciey et al. · Blood Advances Open access 12 May 2020 152
11 Improved seamless mutagenesis by recombineering using ccdB for counterselection Hailong Wang, Xiaoying Bian, Liqiu Xia et al. · Nucleic Acids Research Open access 24 Dec 2013 150
12 Efficient transfer of two large secondary metabolite pathway gene clusters into heterologous hosts by transposition Jun Fu, Silke C. Wenzel, Olena Perlova et al. · Nucleic Acids Research Open access 13 Aug 2008 149
13 An Improved Recombineering Approach by Adding RecA to λ Red Recombination Junping Wang, Mihail Sarov, Jeanette M. J. Rientjes et al. · Molecular Biotechnology 28 Dec 2005 144
14 Phage annealing proteins promote oligonucleotide-directed mutagenesis in Escherichia coli and mouse ES cells Youming Zhang, Joep P. P. Muyrers, Jeanette M. J. Rientjes et al. · BMC Molecular Biology Open access 16 Jan 2003 134
15 Engineering the mouse genome with bacterial artificial chromosomes to create multipurpose alleles Giuseppe Testa, Youming Zhang, Kristina Vintersten et al. · Nature Biotechnology 10 Mar 2003 131
16 Automated Yeast Two-hybrid Screening for Nuclear Receptor-interacting Proteins M. Albers, Harald D. Kranz, Ingo Kober et al. · Molecular & Cellular Proteomics Open access 16 Dec 2004 127
17 Lovo‐cel gene therapy for sickle cell disease: Treatment process evolution and outcomes in the initial groups of the HGB ‐206 study Julie Kanter, Alexis A. Thompson, Francis John Pierciey et al. · American Journal of Hematology Open access 26 Sep 2022 126
18 Single-stranded heteroduplex intermediates in λ Red homologous recombination Marcello Maresca, Axel Erler, Jun Fu et al. · BMC Molecular Biology Open access 2010 126
19 Long-term outcomes of lentiviral gene therapy for the β-hemoglobinopathies: the HGB-205 trial Elisa Magrin et al. · Nature Medicine 2022 105
20 Common schizophrenia risk variants are enriched in open chromatin regions of human glutamatergic neurons Mads E. Hauberg, Jordi Creus‐Muncunill, Jaroslav M. Bendl et al. · Nature Communications Open access 4 Nov 2020 99
21 Reconstitution of the Myxothiazol Biosynthetic Gene Cluster by Red/ET Recombination and Heterologous Expression in Myxococcus xanthus Olena Perlova, Jun Fu, Silvia Kuhlmann et al. · Applied and Environmental Microbiology Open access Dec 2006 90
22 Metabolic Engineering of Pseudomonas putida for Methylmalonyl-CoA Biosynthesis to Enable Complex Heterologous Secondary Metabolite Formation Frank B. Gross, Michael W. Ring, Olena Perlova et al. · Chemistry & Biology Open access Dec 2006 76
23 Simple generation of site-directed point mutations in the Escherichia coli chromosome using Red®/ET® Recombination Ralf Heermann, Tim Zeppenfeld, Kirsten Jung · Microbial Cell Factories Open access 2008 73
24 Direct Cloning, Genetic Engineering, and Heterologous Expression of the Syringolin Biosynthetic Gene Cluster in E. coli through Red/ET Recombineering Xiaoying Bian, Fan Huang, Francis Stewart et al. · ChemBioChem 31 Jul 2012 72
25 Prediction of clinical diagnosis of Alzheimer’s disease, vascular, mixed, and all-cause dementia by a polygenic risk score and APOE status in a community-based cohort prospectively followed over 17 years Hannah R. Stocker, Laura Perna, Korbinian Weigl et al. · Molecular Psychiatry Open access 13 May 2020 71
26 AAV vector-mediated in vivo reprogramming into pluripotency Elena Senís, Lluc Mosteiro, Stefan Wilkening et al. · Nature Communications Open access 3 Jul 2018 68
27 Heterologous Expression and Genetic Engineering of the Tubulysin Biosynthetic Gene Cluster Using Red/ET Recombineering and Inactivation Mutagenesis Yi Chai, Shiping Shan, Kira J. Weissman et al. · Chemistry & Biology Open access Mar 2012 65
28 High-efficiency counterselection recombineering for site-directed mutagenesis in bacterial artificial chromosomes Alexander W. Bird, Axel Erler, Jun Fu et al. · Nature Methods Open access 4 Dec 2011 62
29 Escherichia Coli Strains with Promoter Libraries Constructed by Red/ET Recombination Pave the Way for Transcriptional Fine-Tuning Stephan Braatsch, Søren Helmark, Harald D. Kranz et al. · BioTechniques Open access Sep 2008 58
30 Luminmycins A–C, Cryptic Natural Products from Photorhabdus luminescens Identified by Heterologous Expression in Escherichia coli Xiaoying Bian, Alberto Plaza, Youming Zhang et al. · Journal of Natural Products 21 Aug 2012 56
31 Regulatory systems controlling motility and gene transfer agent production and release in Rhodobacter capsulatus Ryan G. Mercer, Matthew Quinlan, Alexandra R. Rose et al. · FEMS Microbiology Letters 24 Mar 2012 50
32 Long-Term Follow-Up of Hematopoietic Stem-Cell Gene Therapy for Cerebral Adrenoleukodystrophy Pierre F Bougneres, Salima Hacein‐Bey‐Abina, Ivan Labik et al. · Human Gene Therapy Apr 2021 45
33 Investigating the mechanisms of ribonucleotide excision repair in Escherichia coli Alexandra Vaisman, John P. McDonald, Stephan Noll et al. · Mutation research. Fundamental and molecular mechanisms of mutagenesis Open access 2 Feb 2014 44
34 Generation and Clinical Application of Gene-Modified Autologous Epidermal Sheets in Netherton Syndrome: Lessons Learned from a Phase 1 Trial Wei‐Li Di et al. · Human Gene Therapy Open access 10 Jul 2019 41
35 Familial risks between Graves disease and Hashimoto thyroiditis and other autoimmune diseases in the population of Sweden Hauke Thomsen, Xinjun Li, Kristina Sundquist et al. · Journal of Translational Autoimmunity Open access 2020 37
36 A case of T-cell acute lymphoblastic leukemia in retroviral gene therapy for ADA-SCID Daniela Cesana et al. · Nature Communications Open access 30 Apr 2024 34
37 Modification of the Genome of Rhodobacter sphaeroides and Construction of Synthetic Operons Paul R. Jaschke, Rafael G. Saer, Stephan Noll et al. · Methods in enzymology on CD-ROM/Methods in enzymology Book chapter 2011 34
38 Therapeutic expression of human clotting factors IX and × following adeno‐associated viral vector‐mediated intrauterine gene transfer in early‐gestation fetal macaques Jerry Kok Yen Chan, Irene Gil-Fariña, Nuryanti Binti Johana et al. · The FASEB Journal Open access 5 Dec 2018 33
39 Efficient Nuclease-Directed Integration of Lentivirus Vectors into the Human Ribosomal DNA Locus Diana Schenkwein, Saira Afzal, Alisa Nousiainen et al. · Molecular Therapy Open access 22 May 2020 32
40 Haematopoietic gene therapy of non-conditioned patients with Fanconi anaemia-A: results from open-label phase 1/2 (FANCOLEN-1) and long-term clinical trials Paula Rı́o et al. · The Lancet Dec 2024 31
41 ET Recombination: DNA Engineering Using Homologous Recombination in E. coli Joep P. P. Muyrers, Youming Zhang, Vladimı́r Beneš et al. · Humana Press eBooks Book chapter 15 Mar 2004 30
42 BAC Engineering for the Generation of ES Cell-Targeting Constructs and Mouse Transgenes Giuseppe Testa, Kristina Vintersten, Youming Zhang et al. · Humana Press eBooks Book chapter 15 Mar 2004 26
43 Development and characterization of Escherichia coli triple reporter strains for investigation of population heterogeneity in bioprocesses Anna‐Lena Heins, Jan Reyelt, Marlen Schmidt et al. · Microbial Cell Factories Open access 28 Jan 2020 24
44 Multiethnic genome‐wide association study of differentiated thyroid cancer in the EPITHYR consortium Thérèse Truong et al. · International Journal of Cancer 3 Feb 2021 22
45 VSeq-Toolkit: Comprehensive Computational Analysis of Viral Vectors in Gene Therapy Saira Afzal, Raffaele Fronza, Manfred Schmidt · Molecular Therapy — Methods & Clinical Development Open access 30 Mar 2020 18
46 High-level expression, purification and antibacterial activity of bovine lactoferricin and lactoferrampin in Photorhabdus luminescens Zhiru Tang, Youming Zhang, Adrian Francis Stewart et al. · Protein Expression and Purification 26 May 2010 18
47 Resolution of Serious Vaso-Occlusive Pain Crises and Reduction in Patient-Reported Pain Intensity: Results from the Ongoing Phase 1/2 HGB-206 Group C Study of LentiGlobin for Sickle Cell Disease (bb1111) Gene Therapy Alexis A. Thompson, Mark C. Walters, Markus Y. Mapara et al. · Blood 5 Nov 2020 15
48 The balance between the intronic miR-342 and its host gene Evl determines hematopoietic cell fate decision Friederike Herbst, Tonio Johannes Lukas Lang, Elias Eckert et al. · Leukemia Open access 21 May 2021 14
49 Mapping Active Gene-Regulatory Regions in Human Repopulating Long-Term HSCs Peer Wünsche, Elias Eckert, Tim Holland‐Letz et al. · Cell stem cell Open access Jul 2018 14
50 HIV- 1 lentivirus tethering to the genome is associated with transcription factor binding sites found in genes that favour virus survival Saqlain Suleman, Annette M. Payne, Johnathan Bowden et al. · Gene Therapy Open access 5 May 2022 13

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.