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Institution · Georg Speyer Haus

Most cited papers from Georg Speyer Haus

What are the most cited papers from Georg Speyer Haus?

The most cited paper from Georg Speyer Haus is "Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines" (Clotilde Théry et al., 2018), with 11,535 citations. Next come "A framework for advancing our understanding of cancer-associated fibroblasts" (3,962) and "Inflammation and Cancer: Triggers, Mechanisms, and Consequences" (3,881).

Showing 50 of 60 papers. Every paper with more than 232 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines Clotilde Théry et al. · Journal of Extracellular Vesicles Open access382 authors 23 Nov 2018 11,535
2 A framework for advancing our understanding of cancer-associated fibroblasts Erik A. Sahai et al. · Nature reviews. Cancer ReviewOpen access 24 Jan 2020 3,962
3 Inflammation and Cancer: Triggers, Mechanisms, and Consequences Florian R. Greten, Sergei I. Grivennikov · Immunity Open access Jul 2019 3,881
4 Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells Martin Göttlicher, Saverio Minucci, Ping Zhu et al. · The EMBO Journal Open access 17 Dec 2001 1,903
5 The Noncoding RNA MALAT1 Is a Critical Regulator of the Metastasis Phenotype of Lung Cancer Cells Tony Gutschner, Monika Hämmerle, Moritz F. Eissmann et al. · Cancer Research Open access 15 Dec 2012 1,597
6 Human Epidermal Growth Factor Receptor 2 (HER2) –Specific Chimeric Antigen Receptor–Modified T Cells for the Immunotherapy of HER2-Positive Sarcoma Nabil M. Ahmed et al. · Journal of Clinical Oncology Open access 23 Mar 2015 1,001
7 Long Noncoding RNA MALAT1 Regulates Endothelial Cell Function and Vessel Growth Katharina Michalik, Xintian A. You, Yosif Manavski et al. · Circulation Research 7 Mar 2014 961
8 HER2-Specific Chimeric Antigen Receptor–Modified Virus-Specific T Cells for Progressive Glioblastoma Nabil M. Ahmed et al. · JAMA Oncology Open access 20 Apr 2017 854
9 Eph Receptors and Ligands Comprise Two Major Specificity Subclasses and Are Reciprocally Compartmentalized during Embryogenesis Nicholas W. Gale, Sacha J. Holland, David M. Valenzuela et al. · Neuron Open access Jul 1996 851
10 The inflammatory pathogenesis of colorectal cancer Mark R. Schmitt, Florian R. Greten · Nature reviews. Immunology Review 28 Apr 2021 807
11 Genomic instability and myelodysplasia with monosomy 7 consequent to EVI1 activation after gene therapy for chronic granulomatous disease STEFAN P. STEIN et al. · Nature Medicine 24 Jan 2010 787
12 IL-6R/STAT3/miR-34a feedback loop promotes EMT-mediated colorectal cancer invasion and metastasis Matjaž Rokavec, Meryem Gülfem Öner, Huihui Li et al. · Journal of Clinical Investigation Open access 18 Mar 2014 779
13 Genetic relationships determined by a DNA heteroduplex mobility assay: analysis of HIV-1 env genes Eric Delwart, Eugene G. Shpaer, Joost Louwagie et al. · Science 19 Nov 1993 776
14 Optimization of the preparation process for human serum albumin (HSA) nanoparticles Klaus Langer, Sabine Balthasar, Vitali Vogel et al. · International Journal of Pharmaceutics 25 Apr 2003 766
15 Tandem CAR T cells targeting HER2 and IL13Rα2 mitigate tumor antigen escape Meenakshi G. Hegde et al. · Journal of Clinical Investigation Open access 17 Jul 2016 682
16 Visualization of a short-range Wnt gradient in the intestinal stem-cell niche Henner F. Farin, Ingrid Jordens, Mohammed H. Mosa et al. · Nature Feb 2016 556
17 The role of Bcl-2 family members in tumorigenesis Vladimir Kirkin, Stefan Joos, Martin Zörnig · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research Open access 6 Dec 2003 546
18 The histone deacetylase inhibitor valproic acid selectively induces proteasomal degradation of HDAC2 Oliver Holger Krämer, Ping Zhu, Heather P. Ostendorff et al. · The EMBO Journal Open access Jul 2003 530
19 High-Level Transduction and Gene Expression in Hematopoietic Repopulating Cells Using a Human Imunodeficiency Virus Type 1-Based Lentiviral Vector Containing an Internal Spleen Focus Forming Virus Promoter Christophe Demaison, Kathryn L. Parsley, Gaby S. Brouns et al. · Human Gene Therapy May 2002 495
20 Bone marrow niches in haematological malignancies Simón Méndez‐Ferrer, Dominique A. Bonnet, David P. Steensma et al. · Nature reviews. Cancer ReviewOpen access 28 Feb 2020 488
21 Direct Evidence That Polysorbate-80-Coated Poly(Butylcyanoacrylate) Nanoparticles Deliver Drugs to the CNS via Specific Mechanisms Requiring Prior Binding of Drug to the Nanoparticles Jörg Kreuter, Peter Ramge, Valery E. Petrov et al. · Pharmaceutical Research Mar 2003 471
22 TanCAR: A Novel Bispecific Chimeric Antigen Receptor for Cancer Immunotherapy Zakaria Grada, Meenakshi G. Hegde, Tiara T. Byrd et al. · Molecular Therapy — Nucleic Acids Open access 2013 466
23 High-fat-diet-mediated dysbiosis promotes intestinal carcinogenesis independently of obesity Manon Dominique Schulz, Çiğdem Atay, Jessica Heringer et al. · Nature Open access 31 Aug 2014 460
24 Persistent STAT3 Activation in Colon Cancer Is Associated with Enhanced Cell Proliferation and Tumor Growth Florian Matthias Corvinus, Carina med. Orth, Richard Moriggl et al. · Neoplasia Open access Jun 2005 437
25 Global and regional molecular epidemiology of HIV-1, 1990–2015: a systematic review, global survey, and trend analysis Joris Hemelaar et al. · The Lancet Infectious Diseases ReviewOpen access182 authors 30 Nov 2018 425
26 The CD95 Receptor: Apoptosis Revisited Marcus E. Peter, Ralph C. Budd, Julie Desbarats et al. · Cell Open access May 2007 398
27 Loss of the abundant nuclear non-coding RNA MALAT1 is compatible with life and development Moritz F. Eissmann, Tony Gutschner, Monika Hämmerle et al. · RNA Biology Open access Aug 2012 397
28 ErbB2/HER2-Specific NK Cells for Targeted Therapy of Glioblastoma Congcong Zhang, Michael C. Burger, Lukas Jennewein et al. · JNCI Journal of the National Cancer Institute 6 Dec 2015 394
29 Large extracellular vesicles carry most of the tumour DNA circulating in prostate cancer patient plasma Tatyana Vagner, Cristiana Spinelli, Valentina R. Minciacchi et al. · Journal of Extracellular Vesicles Open access 7 Aug 2018 392
30 Myeloid Cell-Derived Reactive Oxygen Species Induce Epithelial Mutagenesis Özge Canli, Adele M. Nicolas, J. R. P. Gupta et al. · Cancer Cell Open access Dec 2017 360
31 3D model for CAR‐mediated cytotoxicity using patient‐derived colorectal cancer organoids Theresa Schnalzger, Marnix HP de Groot, Congcong Zhang et al. · The EMBO Journal Open access 29 Apr 2019 355
32 Selective Inhibition of Tumor Growth by Clonal NK Cells Expressing an ErbB2/HER2-Specific Chimeric Antigen Receptor Kurt Schönfeld et al. · Molecular Therapy Open access 6 Nov 2014 352
33 Inflammatory fibroblasts mediate resistance to neoadjuvant therapy in rectal cancer Adele M. Nicolas et al. · Cancer Cell Open access Feb 2022 351
34 The amino acid transporter SLC7A5 is required for efficient growth of KRAS-mutant colorectal cancer Arafath Kaja Najumudeen et al. · Nature Genetics 2021 339
35 STAT3 activation through IL-6/IL-11 in cancer-associated fibroblasts promotes colorectal tumour development and correlates with poor prognosis Christina Heichler et al. · Gut 4 Nov 2019 339
36 Reactive Oxygen Species Regulate Hematopoietic Stem Cell Self-Renewal, Migration and Development, As Well As Their Bone Marrow Microenvironment Aya Ludin, Shiri Gur‐Cohen, Karin Golan et al. · Antioxidants and Redox Signaling Open access 24 Apr 2014 339
37 NK-92: an ‘off-the-shelf therapeutic’ for adoptive natural killer cell-based cancer immunotherapy Garnet Suck, Marcus Odendahl, Paulina Nowakowska et al. · Cancer Immunology Immunotherapy Open access 11 Nov 2015 333
38 Fructose stimulated de novo lipogenesis is promoted by inflammation Jelena Todoric et al. · Nature Metabolism Open access 24 Aug 2020 327
39 Prognostic significance of polo-like kinase (PLK) expression in non-small cell lung cancer Georg Wolf, Robert Elez, A Doermer et al. · Oncogene 6 Feb 1997 327
40 Jak Stat signaling and cancer: Opportunities, benefits and side effects of targeted inhibition Bernd Groner, Viktoria von Manstein · Molecular and Cellular Endocrinology 31 May 2017 321
41 Activating natural cytotoxicity receptors of natural killer cells in cancer and infection Joachim Koch, Alexander Steinle, Carsten Watzl et al. · Trends in Immunology Review 13 Feb 2013 316
42 Chimeric Antigen Receptor-Engineered NK-92 Cells: An Off-the-Shelf Cellular Therapeutic for Targeted Elimination of Cancer Cells and Induction of Protective Antitumor Immunity Congcong Zhang, Pranav Oberoi, Sarah Oelsner et al. · Frontiers in Immunology Open access 18 May 2017 311
43 Characterization of a Virtually Full-Length Human Immunodeficiency Virus Type 1 Genome of a Prevalent Intersubtype (C/B′) Recombinant Strain in China Ling Su, Marcus Graf, Yuanzhi Zhang et al. · Journal of Virology Open access Dec 2000 299
44 Complexome Profiling Identifies TMEM126B as a Component of the Mitochondrial Complex I Assembly Complex Heinrich Heide, Lea Bleier, Mirco Steger et al. · Cell Metabolism Open access 13 Sep 2012 293
45 Aberrant epithelial GREM1 expression initiates colonic tumorigenesis from cells outside the stem cell niche Hayley L. Belnoue-Davis et al. · Nature Medicine Open access 24 Nov 2014 293
46 Induction and down-regulation of PLK, a humanserine/threonine kinase expressed in proliferating cells andtumors. Uwe Holtrich, Georg Wolf, Andreas Bräuninger et al. · Proceedings of the National Academy of Sciences Open access Mar 1994 285
47 A guideline on the molecular ecosystem regulating ferroptosis Enyong Dai et al. · Nature Cell Biology Open access 29 Feb 2024 282
48 Inflammation: the incubator of the tumor microenvironment Dominic Denk, Florian R. Greten · Trends in cancer Review 27 Jul 2022 280
49 Cancer-Associated Fibroblasts in Inflammation and Antitumor Immunity Kilian B. Kennel, Müge Bozlar, Adalbert F. De Valk et al. · Clinical Cancer Research Open access 18 Nov 2022 278
50 Gene therapy on the move Kerstin B. Kaufmann, Hildegard Büning, Anne Galy et al. · EMBO Molecular Medicine Open access 17 Sep 2013 276

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.