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Most cited papers from German Centre for Cardiovascular Research

What are the most cited papers from German Centre for Cardiovascular Research?

The most cited paper from German Centre for Cardiovascular Research is "The mutational constraint spectrum quantified from variation in 141,456 humans" (Konrad J. Karczewski et al., 2020), with 10,422 citations. Next come "Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease" (9,517) and "Maftools: efficient and comprehensive analysis of somatic variants in cancer" (5,587).

Showing 50 of 60 papers. Every paper with more than 973 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 The mutational constraint spectrum quantified from variation in 141,456 humans Konrad J. Karczewski et al. · Nature Open access177 authors 27 May 2020 10,422
2 Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease Paul M. Ridker et al. · New England Journal of Medicine Open access 27 Aug 2017 9,517
3 Maftools: efficient and comprehensive analysis of somatic variants in cancer Anand Mayakonda, De‐Chen Lin, Yassen Assenov et al. · Genome Research Open access 19 Oct 2018 5,587
4 Genetic studies of body mass index yield new insights for obesity biology The LifeLines Cohort Study et al. · Nature Open access487 authors 10 Feb 2015 4,954
5 2019 ESC/EAS guidelines for the management of dyslipidaemias: Lipid modification to reduce cardiovascular risk François Mach et al. · Atherosclerosis Open access100 authors 31 Aug 2019 4,890
6 Low-density lipoproteins cause atherosclerotic cardiovascular disease. 1. Evidence from genetic, epidemiologic, and clinical studies. A consensus statement from the European Atherosclerosis Society Consensus Panel Brian A. Ference et al. · European Heart Journal Open access 8 Mar 2017 4,032
7 Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression eQTLGen et al. · Nature Genetics Open access218 authors 26 Apr 2018 3,347
8 A reference panel of 64,976 haplotypes for genotype imputation Shane McCarthy et al. · Nature Genetics Open access111 authors 22 Aug 2016 3,318
9 A comprehensive 1000 Genomes–based genome-wide association meta-analysis of coronary artery disease Majid Nikpay et al. · Nature Genetics ReviewOpen access151 authors 7 Sep 2015 2,733
10 Angiotensin–Neprilysin Inhibition in Heart Failure with Preserved Ejection Fraction Scott David Solomon et al. · New England Journal of Medicine Open access Sep 2019 2,429
11 Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression Urmo Võsa et al. · Nature Genetics Open access114 authors Sep 2021 2,339
12 Transcriptome and genome sequencing uncovers functional variation in humans Tuuli Lappalainen et al. · Nature Open access Sep 2013 2,200
13 Early Rhythm-Control Therapy in Patients with Atrial Fibrillation Paulus F. Kirchhof et al. · New England Journal of Medicine Open access 29 Aug 2020 2,193
14 Defining the role of common variation in the genomic and biological architecture of adult human height Andrew R. Wood et al. · Nature Genetics 446 authors 5 Oct 2014 2,114
15 Analysis of shared heritability in common disorders of the brain Verneri Anttila et al. · Science Open access577 authors 21 Jun 2018 2,056
16 Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps Anubha Mahajan et al. · Nature Genetics Open access115 authors Oct 2018 1,968
17 How to diagnose heart failure with preserved ejection fraction: the HFA–PEFF diagnostic algorithm: a consensus recommendation from the Heart Failure Association (HFA) of the European Society of Cardiology (ESC) Burkert Mathias Pieske et al. · European Heart Journal Open access 27 Aug 2019 1,880
18 Cells of the adult human heart Monika Litviňuková et al. · Nature Open access 24 Sep 2020 1,845
19 Systematic identification of trans eQTLs as putative drivers of known disease associations Harm-Jan Westra et al. · Nature Genetics Open access 8 Sep 2013 1,800
20 50 year trends in atrial fibrillation prevalence, incidence, risk factors, and mortality in the Framingham Heart Study: a cohort study Renate B. Schnabel, Xiaoyan Yin, Philimon Nyakauru Gona et al. · The Lancet Open access 7 May 2015 1,789
21 Clinical recommendations for cardiovascular magnetic resonance mapping of T1, T2, T2* and extracellular volume: A consensus statement by the Society for Cardiovascular Magnetic Resonance (SCMR) endorsed by the European Association for Cardiovascular Imaging (EACVI) Daniel Messroghli, James Moon, Vanessa M. Ferreira et al. · Journal of Cardiovascular Magnetic Resonance Open access Dec 2016 1,753
22 New genetic loci link adipose and insulin biology to body fat distribution Dmitry Shungin et al. · Nature Open access410 authors 10 Feb 2015 1,726
23 Two Phase 3 Trials of Inclisiran in Patients with Elevated LDL Cholesterol Kausik Kumar Ray, R. Scott Wright, David G. Kallend et al. · New England Journal of Medicine Open access 18 Mar 2020 1,652
24 Low-density lipoproteins cause atherosclerotic cardiovascular disease: pathophysiological, genetic, and therapeutic insights: a consensus statement from the European Atherosclerosis Society Consensus Panel Jan Borén et al. · European Heart Journal Open access 8 Jan 2020 1,609
25 Calcium and ROS: A mutual interplay Agnes Görlach, Katharina Bertram, Soňa Hudecová et al. · Redox Biology Open access 11 Aug 2015 1,577
26 Epidemiology of Atrial Fibrillation in the 21st Century Jelena Kornej, Christin S. Börschel, Emelia J. Benjamin et al. · Circulation Research Open access 18 Jun 2020 1,563
27 Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits the Million Veteran Program et al. · Nature Genetics Open access281 authors 17 Sep 2018 1,523
28 Roles of Vascular Oxidative Stress and Nitric Oxide in the Pathogenesis of Atherosclerosis Ulrich Förstermann, Ning Xia, Huige Li · Circulation Research 16 Feb 2017 1,505
29 Periodontitis and cardiovascular diseases: Consensus report Mariano Sanz et al. · Journal Of Clinical Periodontology Open access 3 Feb 2020 1,504
30 A genomic mutational constraint map using variation in 76,156 human genomes Siwei Chen et al. · Nature Open access238 authors 6 Dec 2023 1,453
31 SGLT2 inhibitors in patients with heart failure with reduced ejection fraction: a meta-analysis of the EMPEROR-Reduced and DAPA-HF trials Faiez M. Zannad, João Pedro Ferreira, Stuart Pocock et al. · The Lancet ReviewOpen access 30 Aug 2020 1,418
32 Cortical abnormalities in adults and adolescents with major depression based on brain scans from 20 cohorts worldwide in the ENIGMA Major Depressive Disorder Working Group for the ENIGMA-Major Depressive Disorder Working Group et al. · Molecular Psychiatry Open access 3 May 2016 1,385
33 Impact of sex and gender on COVID-19 outcomes in Europe Cathérine Gebhard, Vera Regitz‐Zagrosek, Hannelore K. Neuhauser et al. · Biology of Sex Differences Open access 25 May 2020 1,375
34 Salt-responsive gut commensal modulates TH17 axis and disease Nicola Wilck et al. · Nature Open access Nov 2017 1,326
35 Cardiovascular and kidney outcomes with finerenone in patients with type 2 diabetes and chronic kidney disease: the FIDELITY pooled analysis Rajiv Agarwal, Gerasimos S Filippatos, Bertram Pitt et al. · European Heart Journal Open access Nov 2021 1,295
36 Loneliness in the general population: prevalence, determinants and relations to mental health Manfred Elmar Beutel, Eva Margaretha Klein, Elmar Brähler et al. · BMC Psychiatry Open access 20 Mar 2017 1,288
37 International Exercise Recommendations in Older Adults (ICFSR): Expert Consensus Guidelines Míkel Izquierdo et al. · The journal of nutrition health & aging Open access Jul 2021 1,236
38 Myocarditis and inflammatory cardiomyopathy: current evidence and future directions Carsten Tschöpe, Enrico Ammirati, Biykem Bozkurt et al. · Nature Reviews Cardiology ReviewOpen access 12 Oct 2020 1,235
39 A structural variation reference for medical and population genetics Ryan L. Collins et al. · Nature Open access208 authors 27 May 2020 1,205
40 Association of Cardiometabolic Multimorbidity With Mortality Emanuele Di Angelantonio et al. · JAMA Open access 7 Jul 2015 1,189
41 Effect of Evolocumab on Progression of Coronary Disease in Statin-Treated Patients Stephen James Nicholls, Rishi Puri, Todd J. Anderson et al. · JAMA Open access 15 Nov 2016 1,180
42 Risk thresholds for alcohol consumption: combined analysis of individual-participant data for 599 912 current drinkers in 83 prospective studies Angela M Wood et al. · The Lancet Open access246 authors Apr 2018 1,177
43 Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries Mary Furlan Feitosa et al. · PLoS ONE Open access273 authors 18 Jun 2018 1,174
44 The ACE2/Angiotensin-(1–7)/MAS Axis of the Renin-Angiotensin System: Focus on Angiotensin-(1–7) Robson A.S. Santos, Walkyria Oliveira Sampaio, Andréia Carvalho Alzamora et al. · Physiological Reviews ReviewOpen access 24 Dec 2017 1,174
45 International Clinical Practice Guidelines for Sarcopenia (ICFSR): Screening, Diagnosis and Management Elsa Dent et al. · The journal of nutrition health & aging Open access 21 Nov 2018 1,132
46 Mapping the human genetic architecture of COVID-19 COVID-19 Host Genetics Initiative et al. · Nature Open access3,896 authors 8 Jul 2021 1,130
47 The genetic architecture of type 2 diabetes Christian Fuchsberger et al. · Nature Open access301 authors 11 Jul 2016 1,129
48 Neuroimaging standards for research into small vessel disease—advances since 2013 Marco Duering et al. · The Lancet Neurology Open access 23 May 2023 1,118
49 The power of genetic diversity in genome-wide association studies of lipids Sarah E. Graham et al. · Nature Open access527 authors 9 Dec 2021 1,099
50 Elevated levels of IL-6 and CRP predict the need for mechanical ventilation in COVID-19 Tobias Herold, Vindi Jurinović, Chiara Arnreich et al. · Journal of Allergy and Clinical Immunology Open access 18 May 2020 1,078

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.