| 1 |
KTE-X19 CAR T-Cell Therapy in Relapsed or Refractory Mantle-Cell Lymphoma
Michael Wang et al. · New England Journal of Medicine
Open access |
Apr 2020 |
1,874 |
| 2 |
Influence of Hepatitis C Virus Infection on HIV‐1 Disease Progression and Response to Highly Active Antiretroviral Therapy
Jürgen Kurt Rockstroh, Amanda Mocroft, Vincent Soriano et al. · The Journal of Infectious Diseases
Open access |
19 Aug 2005 |
384 |
| 3 |
Liposomal amphotericin B in combination with caspofungin for invasive aspergillosis in patients with hematologic malignancies
Denis Caillot, Anne Thiébaut, Raoul Herbrecht et al. · Cancer
Open access |
16 Oct 2007 |
194 |
| 4 |
Constipation and the use of laxatives: a comparison between transdermal fentanyl and oral morphine
Lukas Radbruch, Rainer Sabatowski, Georg Loick et al. · Palliative Medicine
|
Mar 2000 |
145 |
| 5 |
Transient lesion in the splenium of the corpus callosum: three further cases in epileptic patients and a pathophysiological hypothesis
Tilman Polster · Journal of Neurology Neurosurgery & Psychiatry
Open access |
Apr 2001 |
143 |
| 6 |
Oral prodrug of remdesivir parent GS-441524 is efficacious against SARS-CoV-2 in ferrets
Robert M. Cox, Josef D. Wolf, Carolin M. Lieber et al. · Nature Communications
Open access |
5 Nov 2021 |
133 |
| 7 |
Single‐Dose Liposomal Amphotericin B in the Treatment of Visceral Leishmaniasis in India: A Multicenter Study
Shyam Sundar, T. K. Jha, C.P. Thakur et al. · Clinical Infectious Diseases
Open access |
5 Sep 2003 |
132 |
| 8 |
Relationship Between Nonsustained Ventricular Tachycardia After Non–ST-Elevation Acute Coronary Syndrome and Sudden Cardiac Death
Benjamin M. Scirica, Eugene Braunwald, Luiz Belardinelli et al. · Circulation
Open access |
20 Jul 2010 |
123 |
| 9 |
Lack of creatine in muscle and brain in an adult with GAMT deficiency
Andreas Schulze, Peter Bachert, Heinz Peter Schlemmer et al. · Annals of Neurology
|
23 Jan 2003 |
119 |
| 10 |
Cyclosporine versus azathioprine in the long‐term treatment of multiple sclerosis—results of the german multicenter study
Ludwig Kappos, U Pätzold, Dierk Dommasch et al. · Annals of Neurology
|
1988 |
109 |
| 11 |
Toward a comprehensive view of cancer immune responsiveness: a synopsis from the SITC workshop
Society for Immunotherapy of Cancer (SITC) Cancer Immune Responsiveness Task For et al. · Journal for ImmunoTherapy of Cancer
Open access |
22 May 2019 |
90 |
| 12 |
Immunotherapy in Triple-Negative Breast Cancer
Leisha A. Emens · The Cancer Journal
|
2021 |
86 |
| 13 |
Prävalenz psychischer Störungen, Psychopathologie und Behandlungsbedarf bei weiblichen und männlichen Gefangenen
Christiane Schönfeld, Frank W. Schneider, Timo Schröder et al. · Der Nervenarzt
|
13 Jun 2005 |
86 |
| 14 |
Direct antiviral properties of TLR ligands against HBV replication in immune-competent hepatocytes
Julie Lucifora, Marc Bonnin, Ludovic Aillot et al. · Scientific Reports
Open access |
29 Mar 2018 |
83 |
| 15 |
Diffuse sclerosing variant of papillary thyroid carcinoma
Sören Schröder, Volker Bay, Klaus Dumke et al. · Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin
|
Jul 1990 |
76 |
| 16 |
Effectiveness and Safety of Tenofovir Disoproxil Fumarate in Chronic Hepatitis B: A 3-Year, Prospective, Real-World Study in France
Patrick Marcellin, Fabien Zoulim, Christophe Hézode et al. · Digestive Diseases and Sciences
Open access |
28 Jan 2016 |
72 |
| 17 |
Computer tomography in pulmonary invasive aspergillosis in hematological patients with neutropenia: An useful tool for diagnosis and assessment of outcome in clinical trials
Denis Caillot, V. Latrabe, Anne Thiébaut et al. · European Journal of Radiology
|
5 Jul 2009 |
72 |
| 18 |
Induction of prolonged early G1arrest by CDK4/CDK6 inhibition reprograms lymphoma cells for durable PI3Kδ inhibition through PIK3IP1
David Chiron, Peter Martin, Maurizio Di Liberto et al. · Cell Cycle
Open access |
15 Jun 2013 |
72 |
| 19 |
Safety of a weekly high dose of liposomal amphotericin B for prophylaxis of invasive fungal infection in immunocompromised patients: PROPHYSOME Study
Catherine Cordonnier, Mohamad Mohty, Catherine Faucher et al. · International Journal of Antimicrobial Agents
|
7 Jan 2008 |
70 |
| 20 |
Durability of Hepatitis B Surface Antigen Loss With Nucleotide Analogue and Peginterferon Therapy in Patients With Chronic Hepatitis B
Anna S. Lok, Fabien Zoulim, Geoffrey M Dusheiko et al. · Hepatology Communications
Open access |
10 Oct 2019 |
69 |
| 21 |
Solvatochromic fluorene-linked nucleoside and DNA as color-changing fluorescent probes for sensing interactions
Dmytro Dziuba, Petr Pospíšil, Ján Matyašovský et al. · Chemical Science
Open access |
2016 |
69 |
| 22 |
The Epidemiology of Acute Liver Failure
Nina Weiler, Andreas Schlotmann, Andreas Anton Schnitzbauer et al. · Deutsches Ärzteblatt international
Open access |
17 Jan 2020 |
63 |
| 23 |
NCCN Guidelines Insights: Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma, Version 1.2017
William G. Wierda et al. · Journal of the National Comprehensive Cancer Network
Open access |
Mar 2017 |
62 |
| 24 |
Polymerase synthesis of DNA labelled with benzylidene cyanoacetamide-based fluorescent molecular rotors: fluorescent light-up probes for DNA-binding proteins
Dmytro Dziuba, Radek Pohl, Michal Hocek · Chemical Communications
Open access |
2015 |
62 |
| 25 |
Azidophenyl as a click-transformable redox label of DNA suitable for electrochemical detection of DNA–protein interactions
Jana Balintová, Jan Špaček, Radek Pohl et al. · Chemical Science
Open access |
16 Sep 2014 |
59 |
| 26 |
Perioral Reflex Myoclonias: A Controlled Study in Patients with JME and Focal Epilepsies
Thomas A. Mayer, Frauke Schroeder, Theodor W. May et al. · Epilepsia
Open access |
Jun 2006 |
59 |
| 27 |
Valproic acid was well tolerated in heavily pretreated pediatric patients with high-grade glioma
Johannes Ernst Alexander Wolff, Christof Maria Kramm, Rolf‐Dieter Kortmann et al. · Journal of Neuro-Oncology
|
4 Aug 2008 |
57 |
| 28 |
Variceal Hemorrhage and Adverse Liver Outcomes in Patients With Cystic Fibrosis Cirrhosis
Wen Ye, Michael R. Narkewicz, Daniel H. Leung et al. · Journal of Pediatric Gastroenterology and Nutrition
Open access |
12 Sep 2017 |
49 |
| 29 |
Spike mutation D614G alters SARS-CoV-2 fitness and neutralization susceptibility
Pei‐Yong Shi et al.
PreprintOpen access |
10 Sep 2020 |
48 |
| 30 |
Comparative Selection of the K65R and M184V/I Mutations in Human Immunodeficiency Virus Type 1-Infected Patients Enrolled in a Trial of First-Line Triple-Nucleoside Analog Therapy (Tonus IMEA 021)
Christophe Delaunay, Françoise Brun‐Vézinet, Roland Landman et al. · Journal of Virology
Open access |
13 Jul 2005 |
46 |
| 31 |
Safety and early efficacy assessment of liposomal daunorubicin (DaunoXome) in adults with refractory or relapsed acute myeloblastic leukaemia: a phase I–II study
Αthanasios Fassas, Régine Buffels, Αchilles Anagnostopoulos et al. · British Journal of Haematology
|
Feb 2002 |
43 |
| 32 |
Pediatric-inspired chemotherapy incorporating pegaspargase is safe and results in high rates of minimal residual disease negativity in adults up to age 60 with Philadelphia chromosome-negative acute lymphoblastic leukemia
Mark Blaine Geyer, Ellen Kelly Ritchie, Arati V. Rao et al. · Haematologica
Open access |
13 Oct 2020 |
42 |
| 33 |
Usefulness of staging systems and prognostic scores for hepatocellular carcinoma treatments
Xavier Adhoute, Guillaume Pénaranda, Jean‐Luc Raoul et al. · World Journal of Hepatology
Open access |
2016 |
42 |
| 34 |
Genotypic Determinants of the Virological Response to Tenofovir Disoproxil Fumarate in Nucleoside Reverse Transcriptase Inhibitor-Experienced Patients
the ANRS AC11 Resistance study group, Bernard Masquelier, Catherine Tamalet et al. · Antiviral Therapy
Open access |
Apr 2004 |
42 |
| 35 |
Early Virologic Failure and Rescue Therapy of Tenofovir, Abacavir, and Lamivudine for Initial Treatment of HIV-1 Infection: TONUS Study
Roland Landman, Diane Descamps, Gilles Peytavin et al. · HIV Clinical Trials
Open access |
Dec 2005 |
40 |
| 36 |
Effect of Levetiracetam on Epileptiform Discharges in Human Neocortical Slices
Ali Gorji, Jörg‐Michael Höhling, Michael Madeja et al. · Epilepsia
|
Dec 2002 |
36 |
| 37 |
Contextual reprogramming of CAR-T cells for treatment of HER2+ cancers
Zhifen Yang et al. · Journal of Translational Medicine
Open access |
7 Nov 2021 |
35 |
| 38 |
Impact of prior therapies and subsequent transplantation on outcomes in adult patients with relapsed or refractory B-cell acute lymphoblastic leukemia treated with brexucabtagene autoleucel in ZUMA-3
Bijal Dinesh Shah et al. · Journal for ImmunoTherapy of Cancer
Open access |
Aug 2023 |
34 |
| 39 |
Liposomal daunorubicin (DaunoXome) for treatment of poor-risk acute leukemia
Domenico Russo, Pier Paolo Piccaluga, Mariagrazia Michieli et al. · Annals of Hematology
|
Aug 2002 |
34 |
| 40 |
Switching the nucleoside reverse transcriptase inhibitor backbone to tenofovir disoproxil fumarate + emtricitabine promptly improves triglycerides and low-density lipoprotein cholesterol in dyslipidaemic patients
M. A. Valantin, Randa Bittar, P. de Truchis et al. · Journal of Antimicrobial Chemotherapy
|
6 Jan 2010 |
33 |
| 41 |
Phosphatidylinositol 3 Kinase δ Inhibitors
Jennifer R. Brown · The Cancer Journal
Open access |
Nov 2019 |
31 |
| 42 |
Long-term neuropsychological outcome after severe head injury with good recovery
Michael A. Conzen, Heinrich Ebel, Eric F. Swart et al. · Brain Injury
|
1992 |
30 |
| 43 |
The Evolving Landscape of Industrial Biocatalysis in Perspective from the ACS Green Chemistry Institute Pharmaceutical Roundtable
Francesco Falcioni, Luke Humphreys, Richard C. Lloyd et al. · ACS Catalysis
Open access |
9 Jun 2025 |
27 |
| 44 |
Including Ratio of Platelets to Liver Stiffness Improves Accuracy of Screening for Esophageal Varices That Require Treatment
Arthur Berger et al. · Clinical Gastroenterology and Hepatology
Open access |
17 Jun 2020 |
27 |
| 45 |
First year of pre-exposure prophylaxis implementation in France with daily or on-demand tenofovir disoproxil fumarate/emtricitabine
Martin Siguier, Robertino M. Mera, Gilles Pialoux et al. · Journal of Antimicrobial Chemotherapy
Open access |
2 May 2019 |
27 |
| 46 |
Antihypertensive Effects of Valsartan/Hydrochlorothiazide Combination in Essential Hypertension
Andor Schmidt, Siegfried A. Adam, Rainer E. Kolloch et al. · Blood Pressure
Open access |
2001 |
27 |
| 47 |
Mercaptopurine for the Treatment of Ulcerative Colitis: A Randomized Placebo-Controlled Trial
Mark Löwenberg, Adriaan Volkers, Sara van Gennep et al. · Journal of Crohn s and Colitis
Open access |
27 Feb 2023 |
26 |
| 48 |
Periphere Nervenstimulation
D. Buschmann, F. Oppel · Der Schmerz
|
14 Apr 1999 |
26 |
| 49 |
Disseminated Fusariosis in Immunocompromised Children—Analysis of Recent Cases Identified in the Global Fungiscope Registry
Angela Haßler, Adrian Lieb, Danila Seidel et al. · The Pediatric Infectious Disease Journal
|
12 Nov 2016 |
25 |
| 50 |
Metastasis of lung Carcinoma to intracranial meningioma - Case report and review of literature
Michael A. Conzen, Hartmut Sollmann, Rolf Schnabel · min - Minimally Invasive Neurosurgery
|
Sep 1986 |
23 |