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Most cited papers from Gilead Sciences (United States)

What are the most cited papers from Gilead Sciences (United States)?

The most cited paper from Gilead Sciences (United States) is "Preexposure Chemoprophylaxis for HIV Prevention in Men Who Have Sex with Men" (Robert M. Grant et al., 2010), with 5,186 citations. Next come "Selection of single-stranded DNA molecules that bind and inhibit human thrombin" (2,479) and "Pre-exposure prophylaxis to prevent the acquisition of HIV-1 infection (PROUD): effectiveness results from the pilot phase of a pragmatic open-label randomised trial" (1,919).

Showing 50 of 59 papers. Every paper with more than 584 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Preexposure Chemoprophylaxis for HIV Prevention in Men Who Have Sex with Men Robert M. Grant et al. · New England Journal of Medicine Open access 23 Nov 2010 5,186
2 Selection of single-stranded DNA molecules that bind and inhibit human thrombin Louis C. Bock, Linda C. Griffin, John A Latham et al. · Nature Feb 1992 2,479
3 Pre-exposure prophylaxis to prevent the acquisition of HIV-1 infection (PROUD): effectiveness results from the pilot phase of a pragmatic open-label randomised trial Sheena McCormack et al. · The Lancet Open access 11 Sep 2015 1,919
4 Comparative therapeutic efficacy of remdesivir and combination lopinavir, ritonavir, and interferon beta against MERS-CoV Timothy P. Sheahan, Amy María Sims, Sarah R. Leist et al. · Nature Communications Open access 10 Jan 2020 1,817
5 Regression of cirrhosis during treatment with tenofovir disoproxil fumarate for chronic hepatitis B: a 5-year open-label follow-up study Patrick Marcellin, Edward John Gane, Marı́a Buti et al. · The Lancet 9 Dec 2012 1,802
6 Sofosbuvir for Previously Untreated Chronic Hepatitis C Infection Eric Lawitz et al. · New England Journal of Medicine 23 Apr 2013 1,794
7 Spike mutation D614G alters SARS-CoV-2 fitness Jessica A. Plante et al. · Nature Open access 26 Oct 2020 1,770
8 ComBat-seq: batch effect adjustment for RNA-seq count data Yuqing Zhang, Giovanni Parmigiani, William Evan Johnson · NAR Genomics and Bioinformatics Open access Sep 2020 1,761
9 Ledipasvir and Sofosbuvir for Untreated HCV Genotype 1 Infection Nezam H. Afdhal et al. · New England Journal of Medicine Open access 12 Apr 2014 1,718
10 Idelalisib and Rituximab in Relapsed Chronic Lymphocytic Leukemia Richard R. Furman et al. · New England Journal of Medicine Open access 22 Jan 2014 1,706
11 On-Demand Preexposure Prophylaxis in Men at High Risk for HIV-1 Infection Jean‐Michel Molina et al. · New England Journal of Medicine Open access Dec 2015 1,670
12 Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses Timothy P. Sheahan et al. · Science Translational Medicine Open access 28 Jun 2017 1,638
13 Prodrugs: design and clinical applications Jarkko Rautio, Hanna Kumpulainen, Tycho Heimbach et al. · Nature Reviews Drug Discovery Review 25 Jan 2008 1,626
14 Therapeutic efficacy of the small molecule GS-5734 against Ebola virus in rhesus monkeys Travis K. Warren et al. · Nature Open access 2 Mar 2016 1,620
15 Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) Is Mediated by the Viral Polymerase and the Proofreading Exoribonuclease Maria L. Agostini, Erica L. Andres, Amy María Sims et al. · mBio Open access 5 Mar 2018 1,518
16 Solubilizing Excipients in Oral and Injectable Formulations Robert G. Strickley · Pharmaceutical Research Feb 2004 1,404
17 Adefovir Dipivoxil for the Treatment of Hepatitis B e Antigen–Positive Chronic Hepatitis B Patrick Marcellin, Ting‐Tsung Chang, Seng Gee Lim et al. · New England Journal of Medicine Open access 26 Feb 2003 1,343
18 Tenofovir-Based Preexposure Prophylaxis for HIV Infection among African Women Jeanne Marisa Marrazzo et al. · New England Journal of Medicine Open access 4 Feb 2015 1,316
19 Ledipasvir and Sofosbuvir for Previously Treated HCV Genotype 1 Infection Nezam H. Afdhal et al. · New England Journal of Medicine 12 Apr 2014 1,312
20 Early Remdesivir to Prevent Progression to Severe Covid-19 in Outpatients Robert Gottlieb et al. · New England Journal of Medicine Open access 22 Dec 2021 1,288
21 Effect of Remdesivir vs Standard Care on Clinical Status at 11 Days in Patients With Moderate COVID-19 Christoph D. Spinner et al. · JAMA Open access 21 Aug 2020 1,283
22 Uptake of pre-exposure prophylaxis, sexual practices, and HIV incidence in men and transgender women who have sex with men: a cohort study Robert M. Grant et al. · The Lancet Infectious Diseases Open access 22 Jul 2014 1,259
23 Daclatasvir plus Sofosbuvir for Previously Treated or Untreated Chronic HCV Infection Mark Sulkowski et al. · New England Journal of Medicine 15 Jan 2014 1,197
24 Initial Use of Ambrisentan plus Tadalafil in Pulmonary Arterial Hypertension Nazzareno Galiè, Joan Albert Barberà, Adaani Frost et al. · New England Journal of Medicine Open access 26 Aug 2015 1,188
25 Ledipasvir and Sofosbuvir for 8 or 12 Weeks for Chronic HCV without Cirrhosis Kris V. Kowdley et al. · New England Journal of Medicine Open access 11 Apr 2014 1,131
26 Sofosbuvir and Velpatasvir for HCV Genotype 1, 2, 4, 5, and 6 Infection Jordan J. Feld et al. · New England Journal of Medicine Open access 16 Nov 2015 1,127
27 Sofosbuvir for Hepatitis C Genotype 2 or 3 in Patients without Treatment Options Ira M. Jacobson et al. · New England Journal of Medicine Open access 23 Apr 2013 1,093
28 Remdesivir is a direct-acting antiviral that inhibits RNA-dependent RNA polymerase from severe acute respiratory syndrome coronavirus 2 with high potency Calvin J. Gordon, Egor P. Tchesnokov, Emma Woolner et al. · Journal of Biological Chemistry Open access 13 Apr 2020 1,040
29 Adefovir Dipivoxil for the Treatment of Hepatitis B e Antigen–Negative Chronic Hepatitis B Stephanos J. Hadziyannis, Nicolaos C. Tassopoulos, E. Jenny Heathcote et al. · New England Journal of Medicine Open access 26 Feb 2003 1,001
30 Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection Emmie de Wit, Friederike Feldmann, Jacqueline Cronin et al. · Proceedings of the National Academy of Sciences Open access 13 Feb 2020 950
31 2015 Gout classification criteria: an American College of Rheumatology/European League Against Rheumatism collaborative initiative Tuhina Neogi et al. · Annals of the Rheumatic Diseases Open access 10 Sep 2015 916
32 Persistence of cccDNA during the natural history of chronic hepatitis B and decline during adefovir dipivoxil therapy1 ☆ Bettina Werle–Lapostolle, Scott Bowden, Stephen Locarnini et al. · Gastroenterology Open access Jun 2004 916
33 Cabotegravir for HIV Prevention in Cisgender Men and Transgender Women Raphael J. Landovitz et al. · New England Journal of Medicine Open access 11 Aug 2021 913
34 The antiviral compound remdesivir potently inhibits RNA-dependent RNA polymerase from Middle East respiratory syndrome coronavirus Calvin J. Gordon, Egor P. Tchesnokov, Joy Y. Feng et al. · Journal of Biological Chemistry Open access 25 Feb 2020 893
35 Tenofovir DF, Emtricitabine, and Efavirenz vs. Zidovudine, Lamivudine, and Efavirenz for HIV Joel E. Gallant, Edwin DeJesus, José Ramón Arribas et al. · New England Journal of Medicine 18 Jan 2006 888
36 Long-term Therapy With Adefovir Dipivoxil for HBeAg-Negative Chronic Hepatitis B for up to 5 Years Stephanos J. Hadziyannis, Nicolaos C. Tassopoulos, E. Jenny Heathcote et al. · Gastroenterology Open access 21 Sep 2006 886
37 Sofosbuvir and Velpatasvir for HCV Genotype 2 and 3 Infection Graham R. Foster et al. · New England Journal of Medicine Open access 17 Nov 2015 860
38 Large-Scale Applications of Amide Coupling Reagents for the Synthesis of Pharmaceuticals Joshua R. Dunetz, Javier Magano, Gerald A. Weisenburger · Organic Process Research & Development 15 Nov 2015 829
39 Simeprevir plus sofosbuvir, with or without ribavirin, to treat chronic infection with hepatitis C virus genotype 1 in non-responders to pegylated interferon and ribavirin and treatment-naive patients: the COSMOS randomised study Eric Lawitz et al. · The Lancet 28 Jul 2014 820
40 Sofosbuvir and Velpatasvir for HCV in Patients with Decompensated Cirrhosis Michael P. Curry et al. · New England Journal of Medicine Open access 16 Nov 2015 813
41 DIVERSITY OF OLIGONUCLEOTIDE FUNCTIONS Larry Gold, Barry A. Polisky, Olke C. Uhlenbeck et al. · Annual Review of Biochemistry Jun 1995 806
42 Ledipasvir and Sofosbuvir Plus Ribavirin for Treatment of HCV Infection in Patients With Advanced Liver Disease Michael Charlton et al. · Gastroenterology Open access 20 Jul 2015 804
43 Sofosbuvir and Ribavirin in HCV Genotypes 2 and 3 Stefan Zeuzem, Geoffrey M Dusheiko, Riina Salupere et al. · New England Journal of Medicine Open access 4 May 2014 803
44 T Cells Genetically Modified to Express an Anti–B-Cell Maturation Antigen Chimeric Antigen Receptor Cause Remissions of Poor-Prognosis Relapsed Multiple Myeloma Jennifer N. Brudno et al. · Journal of Clinical Oncology Open access 29 May 2018 800
45 Weight Gain Following Initiation of Antiretroviral Therapy: Risk Factors in Randomized Comparative Clinical Trials Paul Edward Sax, Kristine Mace Erlandson, Jordan E. Lake et al. · Clinical Infectious Diseases Open access 8 Oct 2019 776
46 Nucleotide Polymerase Inhibitor Sofosbuvir plus Ribavirin for Hepatitis C Edward John Gane, Catherine Ann Malcolm Stedman, Robert H. Hyland et al. · New England Journal of Medicine Open access 2 Jan 2013 765
47 Gene inhibition using antisense oligodeoxynucleotides Richard W. Wagner · Nature Nov 1994 746
48 Particle size reduction for improvement of oral bioavailability of hydrophobic drugs: I. Absolute oral bioavailability of nanocrystalline danazol in beagle dogs Gary G. Liversidge, Kenneth C. Cundy · International Journal of Pharmaceutics Oct 1995 739
49 Clinical benefit of remdesivir in rhesus macaques infected with SARS-CoV-2 Brandi N. Williamson et al. · Nature Open access 9 Jun 2020 737
50 Requirement of p27 Kip1 for Restriction Point Control of the Fibroblast Cell Cycle Steve Coats, W. Michael Flanagan, Jamison L. Nourse et al. · Science 10 May 1996 688

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.