Institution · Gladstone Institutes
Most cited papers from Gladstone Institutes
What are the most cited papers from Gladstone Institutes?
The most cited paper from Gladstone Institutes is "Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors" (Kazutoshi Takahashi, Koji Tanabe, Mari Ohnuki et al., 2007), with 20,424 citations. Next come "Structure, function and diversity of the healthy human microbiome" (12,195) and "Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)" (6,023).
Showing 50 of 60 papers. Every paper with more than 1,331 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors Kazutoshi Takahashi, Koji Tanabe, Mari Ohnuki et al. · Cell | Nov 2007 | 20,424 |
| 2 | Structure, function and diversity of the healthy human microbiome Curtis Huttenhower et al. · Nature | Jun 2012 | 12,195 |
| 3 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) Daniel J. Klionsky et al. · Autophagy | 2 Jan 2016 | 6,023 |
| 4 | Reference-based analysis of lung single-cell sequencing reveals a transitional profibrotic macrophage Dvir Aran, Agnieszka P. Looney, Leqian Liu et al. · Nature Immunology | 4 Jan 2019 | 5,566 |
| 5 | Preexposure Chemoprophylaxis for HIV Prevention in Men Who Have Sex with Men Robert M. Grant et al. · New England Journal of Medicine | 23 Nov 2010 | 5,186 |
| 6 | A SARS-CoV-2 protein interaction map reveals targets for drug repurposing David Ezra Gordon et al. · Nature | 30 Apr 2020 | 4,901 |
| 7 | Apolipoprotein E: Cholesterol Transport Protein with Expanding Role in Cell Biology Robert W. Mahley · Science | 29 Apr 1988 | 4,054 |
| 8 | A communal catalogue reveals Earth’s multiscale microbial diversity Luke Thompson et al. · Nature | 30 Oct 2017 | 2,968 |
| 9 | Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts Masato Nakagawa, Michiyo Koyanagi, Koji Tanabe et al. · Nature Biotechnology | 30 Nov 2007 | 2,802 |
| 10 | A framework for human microbiome research Barbara A. Methé et al. · Nature | Jun 2012 | 2,794 |
| 11 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 1 Daniel J. Klionsky et al. · Autophagy | 2 Jan 2021 | 2,743 |
| 12 | Detection of nonneutral substitution rates on mammalian phylogenies Katherine S. Pollard, Melissa J. Hubisz, Kate R. Rosenbloom et al. · Genome Research | 26 Oct 2009 | 2,615 |
| 13 | Integration of biological networks and gene expression data using Cytoscape Melissa Cline et al. · Nature Protocols | 27 Sep 2007 | 2,601 |
| 14 | The Many Roles of Chemokines and Chemokine Receptors in Inflammation Israel F. Charo, Richard M. Ransohoff · New England Journal of Medicine | 8 Feb 2006 | 2,537 |
| 15 | Direct Reprogramming of Fibroblasts into Functional Cardiomyocytes by Defined Factors Masaki Ieda, Ji‐Dong Fu, Paul Delgado-Olguı́n et al. · Cell | Aug 2010 | 2,491 |
| 16 | Hydrogels with tunable stress relaxation regulate stem cell fate and activity Ovijit Chaudhuri, Luo Gu, Darinka D. Klumpers et al. · Nature Materials | 30 Nov 2015 | 2,484 |
| 17 | Climate warming enhances microbial network complexity and stability Mengting Yuan, Xue Yi Guo, Linwei Wu et al. · Nature Climate Change | 22 Feb 2021 | 2,280 |
| 18 | New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk Josée Dupuis et al. · Nature Genetics | 17 Jan 2010 | 2,239 |
| 19 | Cellular Fatty Acid Metabolism and Cancer Erin Currie, Almut Schulze, Rudolf Zechner et al. · Cell Metabolism | 20 Jun 2013 | 2,179 |
| 20 | Triglyceride accumulation protects against fatty acid-induced lipotoxicity Laura L. Listenberger, Xianlin Han, Sarah Elizabeth Lewis et al. · Proceedings of the National Academy of Sciences | 10 Mar 2003 | 2,126 |
| 21 | A more efficient method to generate integration-free human iPS cells Keisuke Okita, Yasuko Matsumura, Yoshiko Sato et al. · Nature Methods | 3 Apr 2011 | 2,121 |
| 22 | Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death Montserrat Arrasate, Siddhartha S. Mitra, Erik S. Schweitzer et al. · Nature | Oct 2004 | 2,024 |
| 23 | Generation of Mouse Induced Pluripotent Stem Cells Without Viral Vectors Keisuke Okita, Masato Nakagawa, Hyenjong Hong et al. · Science | 9 Oct 2008 | 2,010 |
| 24 | Glioma Groups Based on 1p/19q, IDH , and TERT Promoter Mutations in Tumors Jeanette E. Eckel‐Passow et al. · New England Journal of Medicine | 11 Jun 2015 | 2,009 |
| 25 | Global, regional, and national trends in haemoglobin concentration and prevalence of total and severe anaemia in children and pregnant and non-pregnant women for 1995–2011: a systematic analysis of population-representative data Gretchen A Stevens, Mariel McKenzie Finucane, Luz Maria De‐Regil et al. · The Lancet Global Health | 25 Jun 2013 | 1,983 |
| 26 | Decreased lesion formation in CCR2−/− mice reveals a role for chemokines in the initiation of atherosclerosis Landin F. Boring, Jennifa Gosling, Michael D. Cleary et al. · Nature | Aug 1998 | 1,983 |
| 27 | Regulation of parkinsonian motor behaviours by optogenetic control of basal ganglia circuitry Alexxai V. Kravitz, Benjamin S. Freeze, Philip R. L. Parker et al. · Nature | Jul 2010 | 1,969 |
| 28 | Targeted Degradation of CTCF Decouples Local Insulation of Chromosome Domains from Genomic Compartmentalization Elphège Pierre Nora, Anton A. Goloborodko, Anne-Laure Valton et al. · Cell | May 2017 | 1,954 |
| 29 | Reducing Endogenous Tau Ameliorates Amyloid ß-Induced Deficits in an Alzheimer's Disease Mouse Model Erik D. Roberson, Kimberly A. Scearce-Levie, Jorge J. Palop et al. · Science | 3 May 2007 | 1,918 |
| 30 | Cytoscape Automation: empowering workflow-based network analysis David Otasek, John H. Morris, Jorge Bouças et al. · Genome biology | 2 Sep 2019 | 1,896 |
| 31 | High-Level Neuronal Expression of Aβ1–42in Wild-Type Human Amyloid Protein Precursor Transgenic Mice: Synaptotoxicity without Plaque Formation Lennart Mucke, Eliezer Masliah, Gui-Qiu Yu et al. · Journal of Neuroscience | Jun 2000 | 1,892 |
| 32 | Apolipoprotein E: Far More Than a Lipid Transport Protein Robert W. Mahley, Stanley C. Rall · Annual Review of Genomics and Human Genetics | Sep 2000 | 1,862 |
| 33 | Clearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in mice Jianhui Chang, Yingying Wang, Lijian Shao et al. · Nature Medicine | 14 Dec 2015 | 1,825 |
| 34 | Dopaminergic Loss and Inclusion Body Formation in α-Synuclein Mice: Implications for Neurodegenerative Disorders Eliezer Masliah, Edward M. Rockenstein, Isaac Veinbergs et al. · Science | 18 Feb 2000 | 1,814 |
| 35 | The Simons Genome Diversity Project: 300 genomes from 142 diverse populations Swapan Mallick et al. · Nature | 20 Sep 2016 | 1,804 |
| 36 | Alzheimer Mechanisms and Therapeutic Strategies Yadong Huang, Lennart Mucke · Cell | Mar 2012 | 1,788 |
| 37 | Suppression of Oxidative Stress by β-Hydroxybutyrate, an Endogenous Histone Deacetylase Inhibitor Tadahiro Shimazu, Matthew D. Hirschey, John Newman et al. · Science | 7 Dec 2012 | 1,785 |
| 38 | miR-126 Regulates Angiogenic Signaling and Vascular Integrity Jason E. Fish, Massimo Mattia Santoro, Sarah U. Morton et al. · Developmental Cell | Aug 2008 | 1,733 |
| 39 | Lipid Droplets and Cellular Lipid Metabolism Tobias C. Walther, Robert V. Farese · Annual Review of Biochemistry | 22 May 2012 | 1,730 |
| 40 | Aberrant Excitatory Neuronal Activity and Compensatory Remodeling of Inhibitory Hippocampal Circuits in Mouse Models of Alzheimer's Disease Jorge J. Palop, Jeannie Chin, Erik D. Roberson et al. · Neuron | Sep 2007 | 1,723 |
| 41 | SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation Matthew D. Hirschey, Tadahiro Shimazu, Eric S. Goetzman et al. · Nature | Mar 2010 | 1,706 |
| 42 | Induction of autophagy by spermidine promotes longevity Tobias Eisenberg et al. · Nature Cell Biology | 4 Oct 2009 | 1,699 |
| 43 | Amyloid-β–induced neuronal dysfunction in Alzheimer's disease: from synapses toward neural networks Jorge J. Palop, Lennart Mucke · Nature Neuroscience | 25 Jun 2010 | 1,687 |
| 44 | Preexposure Prophylaxis for HIV Infection among African Women Lut Van Damme et al. · New England Journal of Medicine | 11 Jul 2012 | 1,626 |
| 45 | miR-145 and miR-143 regulate smooth muscle cell fate and plasticity Kimberly R. Cordes, Neil T. Sheehy, Mark P. White et al. · Nature | 5 Jul 2009 | 1,605 |
| 46 | A travel guide to Cytoscape plugins Rintaro Saito, Michael E. Smoot, Keiichiro Ono et al. · Nature Methods | Nov 2012 | 1,579 |
| 47 | Induced pluripotent stem cell technology: a decade of progress Yanhong Shi, Haruhisa Inoue, Joseph C. Wu et al. · Nature Reviews Drug Discovery | 16 Dec 2016 | 1,565 |
| 48 | Autologous Induced Stem-Cell–Derived Retinal Cells for Macular Degeneration Michiko Mandai et al. · New England Journal of Medicine | 15 Mar 2017 | 1,561 |
| 49 | Kynurenines in the mammalian brain: when physiology meets pathology Robert M. Schwarcz, John P. Bruno, Paul J. Muchowski et al. · Nature reviews. Neuroscience | 8 Jun 2012 | 1,554 |
| 50 | The Human Sir2 Ortholog, SIRT2, Is an NAD+-Dependent Tubulin Deacetylase Brian J. North, Brett L. Marshall, Margie T. Borra et al. · Molecular Cell | Feb 2003 | 1,550 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.