Institution · Granta Design (United Kingdom)
Most cited papers from Granta Design (United Kingdom)
What are the most cited papers from Granta Design (United Kingdom)?
The most cited paper from Granta Design (United Kingdom) is "The Medicinal Chemist’s Toolbox: An Analysis of Reactions Used in the Pursuit of Drug Candidates" (Stephen D. Roughley, Allan Michael Jordan, 2011), with 2,771 citations. Next come "Acquired Resistance to Fractionated Radiotherapy Can Be Overcome by Concurrent PD-L1 Blockade" (1,338) and "Twenty years on: the impact of fragments on drug discovery" (1,016).
Showing 50 of 60 papers. Every paper with more than 129 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | The Medicinal Chemist’s Toolbox: An Analysis of Reactions Used in the Pursuit of Drug Candidates Stephen D. Roughley, Allan Michael Jordan · Journal of Medicinal Chemistry | 19 Apr 2011 | 2,771 |
| 2 | Acquired Resistance to Fractionated Radiotherapy Can Be Overcome by Concurrent PD-L1 Blockade Simon J. Dovedi, Amy L. Adlard, Grazyna Lipowska‐Bhalla et al. · Cancer Research | 30 Sep 2014 | 1,338 |
| 3 | Twenty years on: the impact of fragments on drug discovery Daniel A. Erlanson, Stephen W. Fesik, Roderick E. Hubbard et al. · Nature Reviews Drug Discovery | 15 Jul 2016 | 1,016 |
| 4 | The CCP 4 suite: integrative software for macromolecular crystallography Jon Agirre et al. · Acta Crystallographica Section D Structural Biology | 4 May 2023 | 945 |
| 5 | Progress in additive manufacturing on new materials: A review Neng Li, Shuai Huang, Guodong Zhang et al. · Journal of Material Science and Technology | 13 Sep 2018 | 787 |
| 6 | rDock: A Fast, Versatile and Open Source Program for Docking Ligands to Proteins and Nucleic Acids Sergio Ruiz Carmona, Daniel Álvarez-García, Nicolas Foloppe et al. · PLoS Computational Biology | 10 Apr 2014 | 681 |
| 7 | Engineering critical analyses to BS 7910 — the UK guide on methods for assessing the acceptability of flaws in metallic structures C. S. Wiesner, S. J. Maddox, Wei Xu et al. · International Journal of Pressure Vessels and Piping | Dec 2000 | 492 |
| 8 | Biophysics in drug discovery: impact, challenges and opportunities Jean‐Paul Renaud, Chun‐wa Chung, U. Helena Danielson et al. · Nature Reviews Drug Discovery | 12 Aug 2016 | 391 |
| 9 | 3-Dimensional CFD modelling of flow round a threaded friction stir welding tool profile Paul A. Colegrove, Hugh R. Shercliff · Journal of Materials Processing Technology | 28 Jun 2005 | 383 |
| 10 | Fractionated Radiation Therapy Stimulates Antitumor Immunity Mediated by Both Resident and Infiltrating Polyclonal T-cell Populations when Combined with PD-1 Blockade Simon J. Dovedi, Eleanor J. Cheadle, Amy L. Popple et al. · Clinical Cancer Research | 22 May 2017 | 377 |
| 11 | Identification of chemically diverse Chk1 inhibitors by receptor-based virtual screening Nicolas Foloppe, Lisa M. Fisher, Rob Howes et al. · Bioorganic & Medicinal Chemistry | 30 Mar 2006 | 364 |
| 12 | Some comments on models for field enhancement Richard G. Forbes, Christopher John Edgcombe, U. Valdrè · Ultramicroscopy | 21 Jan 2003 | 361 |
| 13 | The Thermodynamics of Protein–Ligand Interaction and Solvation: Insights for Ligand Design Tjelvar S. G. Olsson, Mark Anthony Williams, William R. Pitt et al. · Journal of Molecular Biology | 11 Oct 2008 | 344 |
| 14 | Heteroaromatic Rings of the Future William R. Pitt, David M. Parry, Benjamin Perry et al. · Journal of Medicinal Chemistry | 6 Apr 2009 | 342 |
| 15 | Corrosion challenges towards a sustainable society Roman Bender et al. · Materials and Corrosion | 7 Jul 2022 | 334 |
| 16 | A novel, small molecule inhibitor of Hsc70/Hsp70 potentiates Hsp90 inhibitor induced apoptosis in HCT116 colon carcinoma cells Andrew J. Massey, Douglas S. Williamson, Helen L. Browne et al. · Cancer Chemotherapy and Pharmacology | 12 Dec 2009 | 334 |
| 17 | A review of methods and data to determine raw material criticality Dieuwertje Schrijvers et al. · Resources Conservation and Recycling | 23 Jan 2020 | 319 |
| 18 | Structure-Mechanical Stability Relations of Metal-Organic Frameworks via Machine Learning Peyman Z. Moghadam, Sven M. J. Rogge, Aurelia Li et al. · Matter | 15 May 2019 | 292 |
| 19 | Oxide ceramic coatings on aluminium alloys produced by a pulsed bipolar plasma electrolytic oxidation process Aleksey L. Yerokhin, A.S. Shatrov, В. И. Самсонов et al. · Surface and Coatings Technology | 12 Mar 2005 | 287 |
| 20 | Structure-Activity Relationships in Purine-Based Inhibitor Binding to HSP90 Isoforms Lisa M. Wright, Xavier Barril, Brian William Dymock et al. · Chemistry & Biology | Jun 2004 | 271 |
| 21 | Residual stresses in welded structures R.H. Leggatt · International Journal of Pressure Vessels and Piping | 26 Nov 2007 | 262 |
| 22 | Safe life and damage tolerance aspects of railway axles – A review Uwe Zerbst, S. Beretta, Günther Köhler et al. · Engineering Fracture Mechanics | 23 Oct 2012 | 247 |
| 23 | TREM2 shedding by cleavage at the H157‐S158 bond is accelerated for the Alzheimer's disease‐associated H157Y variant Peter Thornton, Jean Sévalle, Michael J. Deery et al. · EMBO Molecular Medicine | 30 Aug 2017 | 238 |
| 24 | Novel Adenosine-Derived Inhibitors of 70 kDa Heat Shock Protein, Discovered Through Structure-Based Design Douglas S. Williamson, Jenifer Borgognoni, Alexandra Clay et al. · Journal of Medicinal Chemistry | 3 Mar 2009 | 233 |
| 25 | NVP-AUY922: a small molecule HSP90 inhibitor with potent antitumor activity in preclinical breast cancer models Michael Rugaard Jensen, Joseph G. Schoepfer, Thomas Radimerski et al. · Breast Cancer Research | 22 Apr 2008 | 229 |
| 26 | Intratumoral IL12 mRNA Therapy Promotes TH1 Transformation of the Tumor Microenvironment Susannah L. Hewitt et al. · Clinical Cancer Research | 17 Aug 2020 | 228 |
| 27 | Investigation into arc constriction by active fluxes for tungsten inert gas welding David Howse, Bill Lucas · Science and Technology of Welding & Joining | Jun 2000 | 219 |
| 28 | Wire + Arc Additively Manufactured Inconel 718: Effect of post-deposition heat treatments on microstructure and tensile properties Cui Er Seow, Harry Coules, Guiyi Wu et al. · Materials & Design | 24 Aug 2019 | 217 |
| 29 | Towards Predictive Ligand Design With Free-Energy Based Computational Methods? Nicolas Foloppe, Roderick E. Hubbard · Current Medicinal Chemistry | 30 Nov 2006 | 210 |
| 30 | Drug-like Bioactive Structures and Conformational Coverage with the LigPrep/ConfGen Suite: Comparison to Programs MOE and Catalyst I‐Jen Chen, Nicolas Foloppe · Journal of Chemical Information and Modeling | 27 Apr 2010 | 208 |
| 31 | Shielded Hydrogen Bonds as Structural Determinants of Binding Kinetics: Application in Drug Design Peter Schmidtke, Francisco Javier Luque, James B. Murray et al. · Journal of the American Chemical Society | 7 Oct 2011 | 205 |
| 32 | Update on the therapeutic potential of PDE4 inhibitors John G. Montana, Hazel J. Dyke · Expert Opinion on Investigational Drugs | 2002 | 196 |
| 33 | Unveiling the Full Potential of Flexible Receptor Docking Using Multiple Crystallographic Structures Xavier Barril, Sam Morley · Journal of Medicinal Chemistry | 24 May 2005 | 194 |
| 34 | CNS remyelination and inflammation: From basic mechanisms to therapeutic opportunities Robin J.M. Franklin, Mikael Simons · Neuron | 12 Oct 2022 | 190 |
| 35 | Active metal brazing of zirconia W.B. Hanson, K. I. Ironside, John A. Fernie · Acta Materialia | Dec 2000 | 188 |
| 36 | Validation of an empirical RNA-ligand scoring function for fast flexible docking using RiboDock® Sam Morley, Mohammad Farzad Afshar · Journal of Computer-Aided Molecular Design | Mar 2004 | 187 |
| 37 | A literature review of Ti-6Al-4V linear friction welding Anthony R. McAndrew, Paul A. Colegrove, Clément Bühr et al. · Progress in Materials Science | 25 Oct 2017 | 182 |
| 38 | Expectation of life and unexpected death in open spina bifida: a 40‐year complete, non‐selective, longitudinal cohort study Pippa Oakeshott, GILLIAN M. HUNT, Alison Sally Poulton et al. · Developmental Medicine & Child Neurology | 8 Jul 2010 | 178 |
| 39 | Development of a highly sensitive liquid biopsy platform to detect clinically-relevant cancer mutations at low allele fractions in cell-free DNA Davina Gillian Gale et al. · PLoS ONE | 16 Mar 2018 | 174 |
| 40 | Combining Hit Identification Strategies: Fragment-Based and in Silico Approaches to Orally Active 2-Aminothieno[2,3-d]pyrimidine Inhibitors of the Hsp90 Molecular Chaperone Paul A. Brough et al. · Journal of Medicinal Chemistry | 17 Jul 2009 | 174 |
| 41 | Characterization of the influences of FSW tool geometry on welding forces and weld tensile strength using an instrumented tool D.G. Hattingh, C. Blignault, Theo Ian van Niekerk et al. · Journal of Materials Processing Technology | 3 Dec 2007 | 174 |
| 42 | Current perspectives in fragment-based lead discovery (FBLD) Bas Lamoree, Roderick E. Hubbard · Essays in Biochemistry | 8 Nov 2017 | 173 |
| 43 | Diverse Resistance Mechanisms to the Third-Generation ALK Inhibitor Lorlatinib in ALK-Rearranged Lung Cancer Gonzalo Recondo et al. · Clinical Cancer Research | 4 Oct 2019 | 172 |
| 44 | Biocompatibility: Meeting a Key Functional Requirement of Next-Generation Medical Devices Michael N. Helmus, D. F. Gibbons, David Cebon · Toxicologic Pathology | 2008 | 169 |
| 45 | Tracking evolution of aromatase inhibitor resistance with circulating tumour DNA analysis in metastatic breast cancer Charlotte Victoria Fribbens, Isaac García-Murillas, Matthew Beaney et al. · Annals of Oncology | 3 Oct 2017 | 166 |
| 46 | Water Networks Can Determine the Affinity of Ligand Binding to Proteins John F. Darby, Adam P. Hopkins, Seishi Shimizu et al. · Journal of the American Chemical Society | 13 Sep 2019 | 161 |
| 47 | Production of Titanium Deposits by Cold-Gas Dynamic Spray: Numerical Modeling and Experimental Characterization Tiziana Marrocco, David Graham McCartney, Philip Howard Shipway et al. · Journal of Thermal Spray Technology | Jun 2006 | 161 |
| 48 | A new statistical local criterion for cleavage fracture in steel. Part I: model presentation S.R. Bordet, Annette Karstensen, David Knowles et al. · Engineering Fracture Mechanics | 29 May 2004 | 161 |
| 49 | Rational Design of Inhibitors of HIV-1 TAR RNA through the Stabilisation of Electrostatic “Hot Spots” Ben J. Davis, Mohammad Farzad Afshar, Gabriele Varani et al. · Journal of Molecular Biology | 8 Jan 2004 | 159 |
| 50 | Review of fatigue assessment procedures for welded aluminium structures S. J. Maddox · International Journal of Fatigue | 27 May 2003 | 153 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.