| 1 |
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
Daniel J. Klionsky et al. · Autophagy
Open access2,467 authors |
2 Jan 2016 |
6,023 |
| 2 |
Structural and functional properties of SARS-CoV-2 spike protein: potential antivirus drug development for COVID-19
Yuan Huang, Chan Yang, Xin-feng Xu et al. · Acta Pharmacologica Sinica
Open access |
3 Aug 2020 |
2,421 |
| 3 |
The PI3K/AKT pathway in obesity and type 2 diabetes
Xingjun Huang, Guihua Liu, Jiao Guo et al. · International Journal of Biological Sciences
Open access |
2018 |
1,701 |
| 4 |
Association of Blood Glucose Control and Outcomes in Patients with COVID-19 and Pre-existing Type 2 Diabetes
Lihua Zhu et al. · Cell Metabolism
Open access |
May 2020 |
1,667 |
| 5 |
Tumor Microenvironment Characterization in Gastric Cancer Identifies Prognostic and Immunotherapeutically Relevant Gene Signatures
Dongqiang Zeng, Meiyi Li, Rui Zhou et al. · Cancer Immunology Research
|
6 Mar 2019 |
1,113 |
| 6 |
mTOR signaling pathway and mTOR inhibitors in cancer: progress and challenges
Zhilin Zou, Tao Tao, Hongmei Li et al. · Cell & Bioscience
Open access |
10 Mar 2020 |
959 |
| 7 |
Cancer Cell Membrane–Biomimetic Nanoparticles for Homologous-Targeting Dual-Modal Imaging and Photothermal Therapy
Ze Chen, Pengfei Zhao, Zhenyu Luo et al. · ACS Nano
|
7 Nov 2016 |
910 |
| 8 |
M2b macrophage polarization and its roles in diseases
Lexun Wang, Sheng-xi Zhang, Huijuan Wu et al. · Journal of Leukocyte Biology
Open access |
21 Dec 2018 |
901 |
| 9 |
Cancer immunotherapy: Pros, cons and beyond
Shuzhen Tan, Dongpei Li, Xiao Ming Zhu · Biomedicine & Pharmacotherapy
Open access |
18 Jan 2020 |
698 |
| 10 |
Investigating the optimal size of anticancer nanomedicine
Li Tang, Xujuan Yang, Qian Yin et al. · Proceedings of the National Academy of Sciences
Open access |
14 Oct 2014 |
670 |
| 11 |
Network Pharmacology in Research of Chinese Medicine Formula: Methodology, Application and Prospective
Ting-ting Luo, Yuan Lu, Shikai Yan et al. · Chinese Journal of Integrative Medicine
|
2 Apr 2019 |
650 |
| 12 |
RNA N6-methyladenosine demethylase FTO promotes breast tumor progression through inhibiting BNIP3
Yi Niu, Ziyou Lin, Arabella H. Wan et al. · Molecular Cancer
Open access |
28 Mar 2019 |
637 |
| 13 |
Translation of the circular RNA circβ-catenin promotes liver cancer cell growth through activation of the Wnt pathway
Weicheng Liang, Cheuk-Wa Wong, Puping Liang et al. · Genome biology
Open access |
26 Apr 2019 |
556 |
| 14 |
Microsatellite instability: a review of what the oncologist should know
Kai Li, Haiqing Luo, Haiqing Luo et al. · Cancer Cell International
Open access |
13 Jan 2020 |
542 |
| 15 |
Recent Advances in Nanozymes: From Matters to Bioapplications
Yongjian Ai, Zenan Hu, Xiaoping Liang et al. · Advanced Functional Materials
|
16 Dec 2021 |
536 |
| 16 |
In-Hospital Use of Statins Is Associated with a Reduced Risk of Mortality among Individuals with COVID-19
Xiao-Jing Zhang et al. · Cell Metabolism
Open access |
24 Jun 2020 |
505 |
| 17 |
Underestimated health risks: polystyrene micro- and nanoplastics jointly induce intestinal barrier dysfunction by ROS-mediated epithelial cell apoptosis
Boxuan Liang, Yizhou Zhong, Yuji Huang et al. · Particle and Fibre Toxicology
Open access |
7 Jun 2021 |
499 |
| 18 |
Adipocyte-secreted exosomal microRNA-34a inhibits M2 macrophage polarization to promote obesity-induced adipose inflammation
Yong Pan, Xiaoyan Hui, Ruby L.C. Hoo et al. · Journal of Clinical Investigation
Open access |
21 Jan 2019 |
493 |
| 19 |
Core–shell biopolymer nanoparticle delivery systems: Synthesis and characterization of curcumin fortified zein–pectin nanoparticles
Kun Hu, Xiaoxia Huang, Yongqing Gao et al. · Food Chemistry
|
11 Mar 2015 |
471 |
| 20 |
Advances in redox-responsive drug delivery systems of tumor microenvironment
Xiaoshuang Guo, Yuan Cheng, Xiaotian Zhao et al. · Journal of Nanobiotechnology
Open access |
22 Sep 2018 |
458 |
| 21 |
m6A-induced lncRNA RP11 triggers the dissemination of colorectal cancer cells via upregulation of Zeb1
Yingmin Wu, Xiangling Yang, Zhuojia Chen et al. · Molecular Cancer
Open access |
13 Apr 2019 |
454 |
| 22 |
Computational Approaches in Preclinical Studies on Drug Discovery and Development
Fengxu Wu, Yuquan Zhou, Langhui Li et al. · Frontiers in Chemistry
Open access |
11 Sep 2020 |
441 |
| 23 |
FOXP3 promotes tumor growth and metastasis by activating Wnt/β-catenin signaling pathway and EMT in non-small cell lung cancer
Shucai Yang, Yi Liu, Mingyue Li et al. · Molecular Cancer
Open access |
17 Jul 2017 |
431 |
| 24 |
Gut Microbiome Fermentation Determines the Efficacy of Exercise for Diabetes Prevention
Yan Liu, Yao Wang, Yueqiong Ni et al. · Cell Metabolism
Open access |
27 Nov 2019 |
415 |
| 25 |
Thermo‐triggered Release of CRISPR‐Cas9 System by Lipid‐Encapsulated Gold Nanoparticles for Tumor Therapy
Peng Wang, Lingmin Zhang, Wenfu Zheng et al. · Angewandte Chemie International Edition
|
28 Dec 2017 |
410 |
| 26 |
Transplantation of fecal microbiota rich in short chain fatty acids and butyric acid treat cerebral ischemic stroke by regulating gut microbiota
Runzhi Chen, Ying Xu, Peng Wu et al. · Pharmacological Research
|
16 Aug 2019 |
381 |
| 27 |
Research progress on berberine with a special focus on its oral bioavailability
Chang‐Shun Liu, Yu-Rong Zheng, Yingfeng Zhang et al. · Fitoterapia
|
2 Feb 2016 |
360 |
| 28 |
Maintaining HIV care during the COVID-19 pandemic
Hongbo Jiang, Yi Zhou, Weiming Tang · The Lancet HIV
Open access |
6 Apr 2020 |
358 |
| 29 |
N6-methyladenosine regulates glycolysis of cancer cells through PDK4
Zihan Li, Yanxi Peng, Jiexin Li et al. · Nature Communications
Open access |
22 May 2020 |
356 |
| 30 |
tRF/miR-1280 Suppresses Stem Cell–like Cells and Metastasis in Colorectal Cancer
Bingqing Huang, Huipeng Yang, Xixi Cheng et al. · Cancer Research
|
26 Apr 2017 |
348 |
| 31 |
Cocoon-Like Self-Degradable DNA Nanoclew for Anticancer Drug Delivery
Wujin Sun, Tianyue Jiang, Yue Christine Lu et al. · Journal of the American Chemical Society
Open access |
13 Oct 2014 |
334 |
| 32 |
Stimuli‐responsive nanotherapeutics for precision drug delivery and cancer therapy
Yiting Qiao, Jianqin Wan, Liqian Zhou et al. · Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology
|
4 May 2018 |
333 |
| 33 |
Resveratrol encapsulation in core-shell biopolymer nanoparticles: Impact on antioxidant and anticancer activities
Xulin Huang, Yuqing Dai, Jiaxin Cai et al. · Food Hydrocolloids
Open access |
3 Nov 2016 |
308 |
| 34 |
Fabrication of biopolymer nanoparticles by antisolvent precipitation and electrostatic deposition: Zein-alginate core/shell nanoparticles
Kun Hu, David Julian McClements · Food Hydrocolloids
|
16 Sep 2014 |
300 |
| 35 |
Fungal endophytes and their interactions with plants in phytoremediation: A review
Zujun Deng, Lixiang Cao · Chemosphere
|
28 Oct 2016 |
299 |
| 36 |
Prevention and treatment of COVID-19 using Traditional Chinese Medicine: A review
Zhenyu Zhao, Yanda Li, Liang-Yun Zhou et al. · Phytomedicine
Open access |
20 Aug 2020 |
294 |
| 37 |
Epidemiology and Clinical Characteristics of COVID-19
Xiaoyi Huang, Fengxiang Wei, Liang Hu et al. · Archives of Iranian Medicine
Open access |
Apr 2020 |
293 |
| 38 |
Retrieval of Brain Tumors by Adaptive Spatial Pooling and Fisher Vector Representation
Jun Ting Cheng, Wei Yang, Meiyan Huang et al. · PLoS ONE
Open access |
6 Jun 2016 |
290 |
| 39 |
Biofilm formation and control strategies of foodborne pathogens: food safety perspectives
Xihong Zhao, Fenghuan Zhao, Jun Wang et al. · RSC Advances
Open access |
2017 |
284 |
| 40 |
High‐Performance Hydrogel Sensors Enabled Multimodal and Accurate Human–Machine Interaction System for Active Rehabilitation
Hao Henry Wang, Qiongling Ding, Yibing Luo et al. · Advanced Materials
|
14 Dec 2023 |
282 |
| 41 |
TNF antagonist sensitizes synovial fibroblasts to ferroptotic cell death in collagen-induced arthritis mouse models
Jiao Wu, Zhuan Feng, Liang Chen et al. · Nature Communications
Open access |
3 Feb 2022 |
275 |
| 42 |
Mitochondrial damage and activation of the cytosolic DNA sensor cGAS–STING pathway lead to cardiac pyroptosis and hypertrophy in diabetic cardiomyopathy mice
Meiling Yan, Yun Li, Qingmao Luo et al. · Cell Death Discovery
Open access |
10 May 2022 |
274 |
| 43 |
Association of Survival and Immune-Related Biomarkers With Immunotherapy in Patients With Non–Small Cell Lung Cancer
Yunfang Yu, Dongqiang Zeng, Qiyun Ou et al. · JAMA Network Open
Open access |
10 Jul 2019 |
274 |
| 44 |
A composite hydrogel with co-delivery of antimicrobial peptides and platelet-rich plasma to enhance healing of infected wounds in diabetes
Shikun Wei, Pengcheng Xu, Zexin Yao et al. · Acta Biomaterialia
|
30 Jan 2021 |
268 |
| 45 |
Gut microbiota mediates diurnal variation of acetaminophen induced acute liver injury in mice
Shenhai Gong, Tian Lan, Liyan Zeng et al. · Journal of Hepatology
Open access |
8 Mar 2018 |
262 |
| 46 |
Disulfide Bond Bridge Insertion Turns Hydrophobic Anticancer Prodrugs into Self-Assembled Nanomedicines
Yongjun Wang, Dan Liŭ, Qing‐Chuan Zheng et al. · Nano Letters
Open access |
4 Sep 2014 |
252 |
| 47 |
Encapsulation of resveratrol in zein/pectin core-shell nanoparticles: Stability, bioaccessibility, and antioxidant capacity after simulated gastrointestinal digestion
Xulin Huang, Ye Liu, Yan Zou et al. · Food Hydrocolloids
Open access |
25 Feb 2019 |
248 |
| 48 |
Long non-coding RNA CASC11 interacts with hnRNP-K and activates the WNT/β-catenin pathway to promote growth and metastasis in colorectal cancer
Zheying Zhang, Chang Zhou, Yaya Chang et al. · Cancer Letters
|
22 Mar 2016 |
248 |
| 49 |
Advances in understanding the interrelations between leptin resistance and obesity
Haitao Pan, Jiao Guo, Zhengquan Su · Physiology & Behavior
|
12 Apr 2014 |
247 |
| 50 |
Baicalin prevents LPS-induced activation of TLR4/NF-κB p65 pathway and inflammation in mice via inhibiting the expression of CD14
Yajun Fu, Bo Xu, Shaowei Huang et al. · Acta Pharmacologica Sinica
Open access |
26 May 2020 |
239 |