Most cited papers from HEC Pharm (China)

HEC Pharm (China)

What are the most cited papers from HEC Pharm (China)?

The most cited paper from HEC Pharm (China) is "Crack-free single-crystal LiNi0.83Co0.10Mn0.07O2 as cycling/thermal stable cathode materials for high-voltage lithium-ion batteries" (Peipei Pang, Xinxin Tan, Zheng Wang et al., 2020), with 151 citations. Next come "A novel GLP-1 and FGF21 dual agonist has therapeutic potential for diabetes and non-alcoholic steatohepatitis" (139) and "Metformin Protects against Oxidative Stress Injury Induced by Ischemia/Reperfusion via Regulation of the lncRNA-H19/miR-148a-3p/Rock2 Axis" (137).

Published TypeFieldAccessCitations

Showing 50 of 61 papers. Every paper with more than 13 citations is listed.

Most cited papers, sortable by citations and release date
#	Paper
1	Crack-free single-crystal LiNi0.83Co0.10Mn0.07O2 as cycling/thermal stable cathode materials for high-voltage lithium-ion batteries Peipei Pang, Xinxin Tan, Zheng Wang et al. · Electrochimica Acta	30 Oct 2020	151
2	A novel GLP-1 and FGF21 dual agonist has therapeutic potential for diabetes and non-alcoholic steatohepatitis Qi Pan, Shushan Lin, Yu Li et al. · EBioMedicine Open access	2021	139
3	Metformin Protects against Oxidative Stress Injury Induced by Ischemia/Reperfusion via Regulation of the lncRNA-H19/miR-148a-3p/Rock2 Axis Jing Zeng, Long Zhu, Jing Liu et al. · Oxidative Medicine and Cellular Longevity Open access	17 Dec 2019	137
4	Improving the Solubility and Bioavailability of Apixaban via Apixaban–Oxalic Acid Cocrystal Yong Chen, Long Li, Jia Yao et al. · Crystal Growth & Design	31 Mar 2016	131
5	Preclinical Characterization of GLS4, an Inhibitor of Hepatitis B Virus Core Particle Assembly Guoyi Wu, Bo Liu, Yingjun Zhang et al. · Antimicrobial Agents and Chemotherapy Open access	19 Aug 2013	125
6	Effect of niobium doping on the structure and electrochemical performance of LiNi0.5Co0.2Mn0.3O2 cathode materials for lithium ion batteries Zuguang Yang, Wei Xiang, Zhenguo Wu et al. · Ceramics International	9 Dec 2016	98
7	Antiviral Activity and Pharmacokinetics of the Hepatitis B Virus (HBV) Capsid Assembly Modulator GLS4 in Patients With Chronic HBV Infection Hong Zhang, WANG Fengjiao, Xiaoxue Zhu et al. · Clinical Infectious Diseases Open access	8 Jul 2020	79
8	Antibody-Based Drugs and Approaches Against Amyloid-β Species for Alzheimer’s Disease Immunotherapy Jing Liu, Bin Yang, Jun Ke et al. · Drugs & Aging	Oct 2016	67
9	Apical sodium-dependent bile acid transporter, drug target for bile acid related diseases and delivery target for prodrugs: Current and future challenges Ming Li, Qian Wang, Yong Li et al. · Pharmacology & Therapeutics	19 Mar 2020	64
10	Novel benzimidazole-based ratiometric fluorescent probes for acidic pH Yancheng Wu, Jiayi You, Jiang Kai et al. · Dyes and Pigments	21 Sep 2017	62
11	Recent advances in the synthesis of bridgehead (or ring-junction) nitrogen heterocycles via transition metal-catalyzed C–H bond activation and functionalization Biao Nie, Wanqing Wu, Ying‐Jun Zhang et al. · Organic Chemistry Frontiers Open access	2020	58
12	Discovery of hepatitis B virus capsid assembly inhibitors leading to a heteroaryldihydropyrimidine based clinical candidate (GLS4) Qingyun Ren, Xinchang Liu, Zhonghua Luo et al. · Bioorganic & Medicinal Chemistry Open access	19 Dec 2016	58
13	A First-in-Human Trial of GLS4, a Novel Inhibitor of Hepatitis B Virus Capsid Assembly, following Single- and Multiple-Ascending-Oral-Dose Studies with or without Ritonavir in Healthy Adult Volunteers Nan Zhao, Bo Jia, Hong Zhao et al. · Antimicrobial Agents and Chemotherapy Open access	17 Oct 2019	46
14	Highly Enantioselective Synthesis of syn-β-Hydroxy α-Dibenzylamino Esters via DKR Asymmetric Transfer Hydrogenation and Gram-Scale Preparation of Droxidopa Guodong Sun, Zihong Zhou, Zhonghua Luo et al. · Organic Letters	3 Aug 2017	45
15	Safety and efficacy of GLP-1/FGF21 dual agonist HEC88473 in MASLD and T2DM: A randomized, double-blind, placebo-controlled study Xiang Lin, Guixia Wang, Yulei Zhuang et al. · Journal of Hepatology	19 Dec 2024	41
16	Computational Fragment-Based Design Facilitates Discovery of Potent and Selective Monoamine Oxidase-B (MAO-B) Inhibitor Chuanfei Jin, Zhi-Zheng Wang, Kang-Zhi Chen et al. · Journal of Medicinal Chemistry Open access	19 Nov 2020	40
17	Effects of chitosan and water-soluble chitosan micro- and nanoparticles in obese rats fed a high-fat diet Hongliang Zhang, Zhong, Tao Tao et al. · International Journal of Nanomedicine Open access	Jul 2012	39
18	3-((R)-4-(((R)-6-(2-Bromo-4-fluorophenyl)-5-(ethoxycarbonyl)-2-(thiazol-2-yl)-3,6-dihydropyrimidin-4-yl)methyl)morpholin-2-yl)propanoic Acid (HEC72702), a Novel Hepatitis B Virus Capsid Inhibitor Based on Clinical Candidate GLS4 Qingyun Ren, Xinchang Liu, Guanghua Yan et al. · Journal of Medicinal Chemistry Open access	30 Jan 2018	36
19	Rotundic acid ameliorates non-alcoholic steatohepatitis via SREBP-1c/ SCD1 signaling pathway and modulating gut microbiota Huijie Liu, Shengtian Cao, Bao‐Ying Wen et al. · International Immunopharmacology	13 Aug 2021	34
20	Identification and characterization of monoclonal antibody fragments cleaved at the complementarity determining region using orthogonal analytical methods Wenhua Li, Bin Yang, Dongmei Zhou et al. · Journal of Chromatography B	22 Feb 2017	34
21	DNA barcoding the commercial Chinese caterpillar fungus Li Xiang, Jingyuan Song, Tianyi Xin et al. · FEMS Microbiology Letters	Aug 2013	34
22	Antioxidative and Protective Effect of Morchella esculenta against Dextran Sulfate Sodium-Induced Alterations in Liver Shutong Chen, Min Wang, Suresh Veeraperumal et al. · Foods Open access	6 Mar 2023	32
23	Farnesoid X receptor (FXR) agonists induce hepatocellular apoptosis and impair hepatic functions via FXR/SHP pathway Tianwei Zhang, Shanshan Feng, Jiahuan Li et al. · Archives of Toxicology	10 Mar 2022	32
24	ZIF-based boronic acid functionalized metal-organic frameworks for the enrichment of cis-diol-containing luteolin from food samples prior to HPLC Bailin Guo, Xue Chen, Jianghua He et al. · Microchimica Acta	11 Jun 2021	32
25	N-Nitrosodimethylamine formation in metformin hydrochloride sustained-release tablets: Effects of metformin and hypromellose used in drug product formulation Gugu Hao, Rong Hu, Xiaoqin Wang et al. · Journal of Pharmaceutical and Biomedical Analysis	23 Sep 2022	31
26	Capillary Zone Electrophoresis Determination of Five Trace Food Additives in Beverage Samples Using Counterflow Transient Isotachophoresis Jun Tao Feng, Jinxia Li, Wenyi Huang et al. · Food Analytical Methods	19 Oct 2020	31
27	Trilobatin alleviates non-alcoholic fatty liver disease in high-fat diet plus streptozotocin-induced diabetic mice by suppressing NLRP3 inflammasome activation Zhi‐Tong Zhang, Wen-Jiao He, Simin Deng et al. · European Journal of Pharmacology	20 Sep 2022	30
28	Development of an Efficient and Scalable Biocatalytic Route to (3R)-3-Aminoazepane: A Pharmaceutically Important Intermediate Yahui Feng, Zhonghua Luo, Guodong Sun et al. · Organic Process Research & Development	29 Mar 2017	28
29	Biological and Chemical Diversity of Bacteria Associated with a Marine Flatworm Huina Lin, Kai‐Ling Wang, Zehong Wu et al. · Marine Drugs Open access	Sep 2017	26
30	Effects of natural dihydrochalcones in sweet tea ( Lithocarpus polystachyus ) on diabetes: a systematical review and meta-analysis of animal studies Xuemin Chen, Weiqi Yang, Xue Wang et al. · Food & Function Review	2022	25
31	[5]Helicene-based chiral triarylboranes with large luminescence dissymmetry factors over a 10 −2 level: synthesis and design strategy via isomeric tuning of steric substitutions Fei Zhao, Jingyi Zhao, Yu Wang et al. · Dalton Transactions	2022	25
32	Synthesis of hierarchical Sn/SnO nanosheets assembled by carbon-coated hollow nanospheres as anode materials for lithium/sodium ion batteries Fengrong He, Qi Xu, Baoping Zheng et al. · RSC Advances Open access	2020	25
33	Development of an Efficient and Scalable Asymmetric Synthesis of Eliglustat via Ruthenium(II)-Catalyzed Asymmetric Transfer Hydrogenation Guodong Sun, Weilin Jian, Zhonghua Luo et al. · Organic Process Research & Development	23 May 2019	25
34	Reduction and pH dual-sensitive nanovesicles co-delivering doxorubicin and gefitinib for effective tumor therapy Yangui Chen, Mingqiang Li, Hong Ping Xiao et al. · RSC Advances Open access	2018	24
35	Novel diyne-bridged dyes for efficient dye-sensitized solar cells Jing‐Kun Fang, Tengxiao Sun, Yi Tian et al. · Materials Chemistry and Physics	5 Apr 2017	24
36	Discovery of a tricyclic farnesoid X receptor agonist HEC96719, a clinical candidate for treatment of non-alcoholic steatohepatitis Shengtian Cao, Xinye Yang, Zheng Zhang et al. · European Journal of Medicinal Chemistry Open access	29 Dec 2021	23
37	Synthesis of 2,1-Benzoisoxazole-Containing 1,2,3-Triazoles through Copper-Catalyzed Three-Component Domino Reactions of o-Bromoacetophenones, Aldehydes, and Sodium Azide Yuwei Wang, Pei Zhi Yu, Qingyun Ren et al. · The Journal of Organic Chemistry	3 Jan 2020	23
38	Discovery and characterization of antibody variants using mass spectrometry-based comparative analysis for biosimilar candidates of monoclonal antibody drugs Wenhua Li, Bin Yang, Dongmei Zhou et al. · Journal of Chromatography B	12 May 2016	23
39	Deep Profiling of Immunosuppressive Glycosphingolipids and Sphingomyelins in Wild Cordyceps Jianing Mi, Yuwei Han, Yingqiong Xu et al. · Journal of Agricultural and Food Chemistry	30 Jul 2018	22
40	Development of Apremilast Solid Dispersion Using TPGS and PVPVA with Enhanced Solubility and Bioavailability Liuhong Yang, Penghui Wu, Jinchao Xu et al. · AAPS PharmSciTech	23 Apr 2021	21
41	The Current Status and Perspectives of Delivery Strategy for Boronbased Drugs Yinghuai Zhu, Xinglong Lin, Hongming Xie et al. · Current Medicinal Chemistry	11 Sep 2018	21
42	Design, synthesis and evaluation of novel monoamine oxidase B (MAO-B) inhibitors with improved pharmacokinetic properties for Parkinson's disease Chao Yi, Xinchang Liu, Kangzhi Chen et al. · European Journal of Medicinal Chemistry Open access	24 Mar 2023	19
43	Co-delivery of Doxorubicin and Afatinib with pH-responsive Polymeric Nanovesicle for Enhanced Lung Cancer Therapy Heng-Ye Gong, Yangui Chen, Xingsu Yu et al. · Chinese Journal of Polymer Science	4 Jun 2019	19
44	Discovery of a Potent and Orally Bioavailable Xanthine Oxidase/Urate Transporter 1 Dual Inhibitor as a Potential Treatment for Hyperuricemia and Gout Xinye Yang, Yong Li, Shengqiang Pan et al. · Journal of Medicinal Chemistry Open access	7 Aug 2024	18
45	Enhancing monoamine oxidase B inhibitory activity via chiral fluorination: Structure-activity relationship, biological evaluation, and molecular docking study Zhi-Zheng Wang, Chao Yi, Kang-Zhi Chen et al. · European Journal of Medicinal Chemistry Open access	Dec 2021	18
46	Synthesis, fungicidal activity, and 3D-QSAR of tetrazole derivatives containing phenyloxadiazole moieties Yi-Tao Li, Wenqiang Yao, Si Zhou et al. · Bioorganic & Medicinal Chemistry Letters	24 Dec 2020	18
47	Screening of Tyrosinase, Xanthine Oxidase, and α-Glucosidase Inhibitors from Polygoni Cuspidati Rhizoma et Radix by Ultrafiltration and HPLC Analysis Jing Chen, Qi Huang, Zhuobin He et al. · Molecules Open access	18 May 2023	17
48	η6‐Arene CH−O Interaction Directed Dynamic Kinetic Resolution – Asymmetric Transfer Hydrogenation (DKR‐ATH) of α‐Keto/enol‐Lactams Zhonghua Luo, Guodong Sun, Shuming Wu et al. · Advanced Synthesis & Catalysis	22 Apr 2021	17
49	Matrix precipitation: A general strategy to eliminate matrix interference for pharmaceutical toxic impurities analysis Xiaojing Yang, Xuewu Xiong, Ji Cao et al. · Journal of Chromatography A	24 Dec 2014	17
50	Microneedle patch with pure drug tips for delivery of liraglutide: pharmacokinetics in rats and minipigs Hongbing Lin, Jinbin Liu, Yulin Hou et al. · Drug Delivery and Translational Research	15 Apr 2024	16

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.