| 1 |
Pathological complete response and long-term clinical benefit in breast cancer: the CTNeoBC pooled analysis
Patricia Cortazar et al. · The Lancet
Open access |
13 Feb 2014 |
4,858 |
| 2 |
Pembrolizumab for Early Triple-Negative Breast Cancer
Peter Schmid et al. · New England Journal of Medicine
Open access |
26 Feb 2020 |
3,298 |
| 3 |
Trastuzumab Emtansine for Residual Invasive HER2-Positive Breast Cancer
Gϋnter von Minckwitz et al. · New England Journal of Medicine
Open access |
5 Dec 2018 |
2,689 |
| 4 |
Cardiovascular Magnetic Resonance in Myocarditis: A JACC White Paper
Matthias G. Friedrich, Udo P Sechtem, Jeanette Schulz‐Menger et al. · Journal of the American College of Cardiology
Open access |
Apr 2009 |
2,526 |
| 5 |
Tumour-infiltrating lymphocytes and prognosis in different subtypes of breast cancer: a pooled analysis of 3771 patients treated with neoadjuvant therapy
Carsten Denkert et al. · The Lancet Oncology
|
8 Dec 2017 |
2,205 |
| 6 |
Progression-free survival in gastrointestinal stromal tumours with high-dose imatinib: randomised trial
Jaap Verweij, Paolo Giovanni Casali, John Raymond Zalcberg et al. · The Lancet
|
Sep 2004 |
1,676 |
| 7 |
Soft tissue and visceral sarcomas: ESMO–EURACAN Clinical Practice Guidelines for diagnosis, treatment and follow-up
Paolo Giovanni Casali et al. · Annals of Oncology
Open access |
28 Mar 2018 |
1,636 |
| 8 |
Association analysis identifies 65 new breast cancer risk loci
Kyriaki Michailidou et al. · Nature
Open access362 authors |
20 Oct 2017 |
1,602 |
| 9 |
Standardized image interpretation and post processing in cardiovascular magnetic resonance: Society for Cardiovascular Magnetic Resonance (SCMR) Board of Trustees Task Force on Standardized Post Processing
Jeanette Schulz‐Menger, David A. Bluemke, Jens Bremerich et al. · Journal of Cardiovascular Magnetic Resonance
Open access |
2013 |
1,528 |
| 10 |
Sentinel-lymph-node biopsy in patients with breast cancer before and after neoadjuvant chemotherapy (SENTINA): a prospective, multicentre cohort study
Thorsten Kuehn, Ingo Bauerfeind, Tanja Natascha Fehm et al. · The Lancet Oncology
|
14 May 2013 |
1,498 |
| 11 |
Sodium chloride drives autoimmune disease by the induction of pathogenic TH17 cells
Markus Kleinewietfeld, Arndt Manzel, Jens Marc Titze et al. · Nature
Open access |
5 Mar 2013 |
1,405 |
| 12 |
Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes
Nasim Mavaddat et al. · The American Journal of Human Genetics
Open access269 authors |
13 Dec 2018 |
1,213 |
| 13 |
Soft tissue and visceral sarcomas: ESMO–EURACAN–GENTURIS Clinical Practice Guidelines for diagnosis, treatment and follow-up☆
Alessandro Gronchi et al. · Annals of Oncology
Open access |
22 Jul 2021 |
1,057 |
| 14 |
11 years' follow-up of trastuzumab after adjuvant chemotherapy in HER2-positive early breast cancer: final analysis of the HERceptin Adjuvant (HERA) trial
David Cameron, Martine J Piccart, Richard D. Gelber et al. · The Lancet
Open access |
16 Feb 2017 |
1,052 |
| 15 |
Neoadjuvant carboplatin in patients with triple-negative and HER2-positive early breast cancer (GeparSixto; GBG 66): a randomised phase 2 trial
Gϋnter von Minckwitz et al. · The Lancet Oncology
|
30 Apr 2014 |
1,048 |
| 16 |
Standardized image interpretation and post-processing in cardiovascular magnetic resonance - 2020 update
Jeanette Schulz‐Menger, David A. Bluemke, Jens Bremerich et al. · Journal of Cardiovascular Magnetic Resonance
Open access |
2020 |
1,027 |
| 17 |
A new prognostic index (MIPI) for patients with advanced-stage mantle cell lymphoma
Eva Hoster, Martin H. Dreyling, Wolfram Klapper et al. · Blood
|
25 Oct 2007 |
986 |
| 18 |
One vs Three Years of Adjuvant Imatinib for Operable Gastrointestinal Stromal Tumor
Heikki Joensuu et al. · JAMA
|
27 Mar 2012 |
982 |
| 19 |
Macrophages regulate salt-dependent volume and blood pressure by a vascular endothelial growth factor-C–dependent buffering mechanism
Agnes Machnik et al. · Nature Medicine
|
May 2009 |
971 |
| 20 |
Common genetic variants influence human subcortical brain structures
The Alzheimer’s Disease Neuroimaging Initiative et al. · Nature
Open access291 authors |
20 Jan 2015 |
934 |
| 21 |
Clinical Characteristics and Cardiovascular Magnetic Resonance Findings in Stress (Takotsubo) Cardiomyopathy
Ingo Eitel, Florian von Knobelsdorff‐Brenkenhoff, Peter Bernhardt et al. · JAMA
|
19 Jul 2011 |
815 |
| 22 |
Lisocabtagene maraleucel versus standard of care with salvage chemotherapy followed by autologous stem cell transplantation as second-line treatment in patients with relapsed or refractory large B-cell lymphoma (TRANSFORM): results from an interim analysis of an open-label, randomised, phase 3 trial
Manali Kamdar et al. · The Lancet
Open access |
Jun 2022 |
799 |
| 23 |
Molecular response to treatment redefines all prognostic factors in children and adolescents with B-cell precursor acute lymphoblastic leukemia: results in 3184 patients of the AIEOP-BFM ALL 2000 study
Valentino Conter et al. · Blood
Open access |
12 Feb 2010 |
795 |
| 24 |
Addition of the PARP inhibitor veliparib plus carboplatin or carboplatin alone to standard neoadjuvant chemotherapy in triple-negative breast cancer (BrighTNess): a randomised, phase 3 trial
Sibylle Loibl, Joyce O’Shaughnessy, Michael Untch et al. · The Lancet Oncology
|
28 Feb 2018 |
781 |
| 25 |
Gastrointestinal stromal tumours: ESMO–EURACAN Clinical Practice Guidelines for diagnosis, treatment and follow-up
Paolo Giovanni Casali et al. · Annals of Oncology
Open access |
28 Mar 2018 |
759 |
| 26 |
Survival and prognosis with osteosarcoma: outcomes in more than 2000 patients in the EURAMOS-1 (European and American Osteosarcoma Study) cohort
Sigbjørn Smeland et al. · European Journal of Cancer
Open access |
27 Jan 2019 |
748 |
| 27 |
Color Duplex Ultrasonography in the Diagnosis of Temporal Arteritis
Wolfgang Schmidt, Helga E. Kraft, Klaus Vorpahl et al. · New England Journal of Medicine
Open access |
6 Nov 1997 |
719 |
| 28 |
A randomised phase II study investigating durvalumab in addition to an anthracycline taxane-based neoadjuvant therapy in early triple-negative breast cancer: clinical results and biomarker analysis of GeparNuevo study
S. Loibl et al. · Annals of Oncology
Open access |
7 May 2019 |
714 |
| 29 |
Prevention of cardiac dysfunction during adjuvant breast cancer therapy (PRADA): a 2 × 2 factorial, randomized, placebo-controlled, double-blind clinical trial of candesartan and metoprolol
Geeta Gulati, Siri Lagethon Heck, Anne Hansen Ree et al. · European Heart Journal
Open access |
21 Feb 2016 |
696 |
| 30 |
Activation of the Peripheral Endocannabinoid System in Human Obesity
Stefan Engeli, Jana Böhnke, Mareike Feldpausch et al. · Diabetes
Open access |
Oct 2005 |
696 |
| 31 |
Bone sarcomas: ESMO–PaedCan–EURACAN Clinical Practice Guidelines for diagnosis, treatment and follow-up
Paolo Giovanni Casali et al. · Annals of Oncology
Open access |
2 Aug 2018 |
655 |
| 32 |
Survival advantage for irinotecan versus best supportive care as second-line chemotherapy in gastric cancer – A randomised phase III study of the Arbeitsgemeinschaft Internistische Onkologie (AIO)
Peter C Thuss-Patience, Albrecht Kretzschmar, Dmitry Bichev et al. · European Journal of Cancer
|
13 Jul 2011 |
617 |
| 33 |
Risk-adjusted therapy of acute lymphoblastic leukemia can decrease treatment burden and improve survival: treatment results of 2169 unselected pediatric and adolescent patients enrolled in the trial ALL-BFM 95
Anja Möricke et al. · Blood
Open access |
19 Feb 2008 |
616 |
| 34 |
Treatment with trastuzumab for 1 year after adjuvant chemotherapy in patients with HER2-positive early breast cancer: a 4-year follow-up of a randomised controlled trial
Luca Gianni et al. · The Lancet Oncology
|
26 Feb 2011 |
614 |
| 35 |
Gastrointestinal stromal tumours: ESMO–EURACAN–GENTURIS Clinical Practice Guidelines for diagnosis, treatment and follow-up
Paolo Giovanni Casali et al. · Annals of Oncology
Open access |
21 Sep 2021 |
608 |
| 36 |
Lower tidal volume strategy (≈3 ml/kg) combined with extracorporeal CO2 removal versus ‘conventional’ protective ventilation (6 ml/kg) in severe ARDS
Thomas Bein, Steffen Weber‐Carstens, Anton Goldmann et al. · Intensive Care Medicine
Open access |
9 Jan 2013 |
604 |
| 37 |
Recombinant human erythropoiesis-stimulating agents and mortality in patients with cancer: a meta-analysis of randomised trials
Julia Bohlius et al. · The Lancet
Review |
May 2009 |
598 |
| 38 |
Cerebral amyloid-β PET with florbetaben (18F) in patients with Alzheimer's disease and healthy controls: a multicentre phase 2 diagnostic study
Henryk Barthel, Hermann‐Josef Gertz, Stefan H. J. Dresel et al. · The Lancet Neurology
|
11 Apr 2011 |
596 |
| 39 |
Adjuvant chemotherapy with doxorubicin, ifosfamide, and lenograstim for resected soft-tissue sarcoma (EORTC 62931): a multicentre randomised controlled trial
Penella J. Woll, Peter Reichardt, Axel Le Cesne et al. · The Lancet Oncology
|
3 Sep 2012 |
596 |
| 40 |
Safety and efficacy of denosumab for adults and skeletally mature adolescents with giant cell tumour of bone: interim analysis of an open-label, parallel-group, phase 2 study
Sant P. Chawla, Robert Mikael Henshaw, Leanne L. Seeger et al. · The Lancet Oncology
|
15 Jul 2013 |
589 |
| 41 |
Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses
Haoyu Zhang et al. · Nature Genetics
Open access276 authors |
18 May 2020 |
587 |
| 42 |
Clinical and molecular characteristics of HER2-low-positive breast cancer: pooled analysis of individual patient data from four prospective, neoadjuvant clinical trials
Carsten Denkert et al. · The Lancet Oncology
|
9 Jul 2021 |
581 |
| 43 |
Anticoagulant Reversal, Blood Pressure Levels, and Anticoagulant Resumption in Patients With Anticoagulation-Related Intracerebral Hemorrhage
Joji B. Kuramatsu et al. · JAMA
|
24 Feb 2015 |
568 |
| 44 |
Comparison of MAPIE versus MAP in patients with a poor response to preoperative chemotherapy for newly diagnosed high-grade osteosarcoma (EURAMOS-1): an open-label, international, randomised controlled trial
Neyssa M. Marina et al. · The Lancet Oncology
Open access |
31 Aug 2016 |
559 |
| 45 |
Overall Survival with Pembrolizumab in Early-Stage Triple-Negative Breast Cancer
Peter Schmid et al. · New England Journal of Medicine
Open access |
15 Sep 2024 |
544 |
| 46 |
Safety and efficacy of first-line bevacizumab with FOLFOX, XELOX, FOLFIRI and fluoropyrimidines in metastatic colorectal cancer: the BEAT study
Eric Van Cutsem, Fernando Rivera, Scott R. Berry et al. · Annals of Oncology
Open access |
May 2009 |
536 |
| 47 |
Long-term results of five consecutive trials in childhood acute lymphoblastic leukemia performed by the ALL-BFM study group from 1981 to 2000
Anja Möricke et al. · Leukemia
|
10 Dec 2009 |
527 |
| 48 |
Increased Vascular Smooth Muscle Contractility in TRPC6−/− Mice
Alexander M. Dietrich, Michael Mederos y Schnitzler, Maik Gollasch et al. · Molecular and Cellular Biology
Open access |
29 Jul 2005 |
516 |
| 49 |
The Salvaged Area at Risk in Reperfused Acute Myocardial Infarction as Visualized by Cardiovascular Magnetic Resonance
Matthias G. Friedrich, Hassan Abdel‐Aty, Andrew J. Taylor et al. · Journal of the American College of Cardiology
Open access |
Apr 2008 |
513 |
| 50 |
2 years versus 1 year of adjuvant trastuzumab for HER2-positive breast cancer (HERA): an open-label, randomised controlled trial
Aron Goldhirsch et al. · The Lancet
|
17 Jul 2013 |
504 |