| 1 |
Hotspot Mutations in H3F3A and IDH1 Define Distinct Epigenetic and Biological Subgroups of Glioblastoma
Dominik Sturm et al. · Cancer Cell
Open access |
Oct 2012 |
1,881 |
| 2 |
Efficacy and safety of intratumoral thermotherapy using magnetic iron-oxide nanoparticles combined with external beam radiotherapy on patients with recurrent glioblastoma multiforme
K. Maier-Hauff, Frank Ulrich, Dirk Nestler et al. · Journal of Neuro-Oncology
Open access |
15 Sep 2010 |
1,423 |
| 3 |
The target landscape of clinical kinase drugs
Susan Klaeger et al. · Science
Open access |
30 Nov 2017 |
905 |
| 4 |
Recommendations for the Management of Herpes Zoster
Robert H. Dworkin et al. · Clinical Infectious Diseases
Open access |
Dec 2006 |
854 |
| 5 |
Autosomal dominant immune dysregulation syndrome in humans with CTLA4 mutations
Desirée Schubert et al. · Nature Medicine
Open access |
20 Oct 2014 |
847 |
| 6 |
The German hospital malnutrition study
Matthias Pirlich, Tatjana Schütz, Kristina Norman et al. · Clinical Nutrition
|
19 May 2006 |
721 |
| 7 |
An Individual Patient Data Meta-Analysis of the Long-Term Outcome of Randomised Studies Comparing Intravesical Mitomycin C versus Bacillus Calmette-Guérin for Non–Muscle-Invasive Bladder Cancer
Per‐Uno Malmström, Richard J Sylvester, David Crawford et al. · European Urology
ReviewOpen access |
25 Apr 2009 |
660 |
| 8 |
Optical properties of selected native and coagulated human brain tissues in vitro in the visible and near infrared spectral range
Anna N. Yaroslavsky, P. C. Schulze, Ilya V. Yaroslavsky et al. · Physics in Medicine and Biology
Open access |
6 Jun 2002 |
651 |
| 9 |
A randomized multicentre trial to compare revascularization with optimal medical therapy for the treatment of chronic total coronary occlusions
Gerald S. Werner et al. · European Heart Journal
Open access |
4 Apr 2018 |
588 |
| 10 |
Large deletions and point mutations involving the dedicator of cytokinesis 8 (DOCK8) in the autosomal-recessive form of hyper-IgE syndrome
Karin R. Engelhardt et al. · Journal of Allergy and Clinical Immunology
Open access |
Dec 2009 |
534 |
| 11 |
Ultrasound guidance versus anatomical landmarks for internal jugular vein catheterization
Patrick Braß, Martin Hellmich, Laurentius Kolodziej et al. · Cochrane Database of Systematic Reviews
Open access |
9 Jan 2015 |
473 |
| 12 |
Phenotype, penetrance, and treatment of 133 cytotoxic T-lymphocyte antigen 4–insufficient subjects
Charlotte Schwab et al. · Journal of Allergy and Clinical Immunology
Open access |
3 May 2018 |
455 |
| 13 |
European Organisation for Research and Treatment of Cancer consensus recommendations for the treatment of mycosis fungoides/Sézary syndrome – Update 2017
Franz Trautinger, Johanna Eder, Chalid Assaf et al. · European Journal of Cancer
Open access |
31 Mar 2017 |
452 |
| 14 |
Effect of Peroral Endoscopic Myotomy vs Pneumatic Dilation on Symptom Severity and Treatment Outcomes Among Treatment-Naive Patients With Achalasia
Fraukje A. Ponds, Paul Fockens, Aaltje Lei et al. · JAMA
Open access |
9 Jul 2019 |
395 |
| 15 |
Rapid Tachyphylaxis of the Glucagon-Like Peptide 1–Induced Deceleration of Gastric Emptying in Humans
Michael Albrecht Nauck, Guido Kemmeries, Jens Juul Holst et al. · Diabetes
Open access |
23 Mar 2011 |
386 |
| 16 |
THALIDOMIDE AND CONGENITAL ABNORMALITIES
Widukind Lenz, RudolfA. Pfeiffer, Wilhelm Kosenow et al. · The Lancet
|
1962 |
379 |
| 17 |
Impact of treatment delay on mortality in ST-segment elevation myocardial infarction (STEMI) patients presenting with and without haemodynamic instability: results from the German prospective, multicentre FITT-STEMI trial
Karl Heinrich Scholz, Sebastian K.G. Maier, Lars Siegfried Maier et al. · European Heart Journal
Open access |
18 Jan 2018 |
377 |
| 18 |
DOCK8 Deficiency: Clinical and Immunological Phenotype and Treatment Options - a Review of 136 Patients
On behalf of the inborn errors working party of EBMT et al. · Journal of Clinical Immunology
Open access |
27 Jan 2015 |
322 |
| 19 |
Long-term follow-up of IPEX syndrome patients after different therapeutic strategies: An international multicenter retrospective study
Federica Barzaghi et al. · Journal of Allergy and Clinical Immunology
Open access |
11 Dec 2017 |
321 |
| 20 |
Ultrasound guidance versus anatomical landmarks for subclavian or femoral vein catheterization
Patrick Braß, Martin Hellmich, Laurentius Kolodziej et al. · Cochrane Database of Systematic Reviews
Open access |
9 Jan 2015 |
321 |
| 21 |
Definitions and classification of malformations of cortical development: practical guidelines
Mariasavina Severino, Ana Filipa Geraldo, Norbert Utz et al. · Brain
Open access |
11 May 2020 |
311 |
| 22 |
Genome-wide analysis of 53,400 people with irritable bowel syndrome highlights shared genetic pathways with mood and anxiety disorders
Chris Q. Eijsbouts et al. · Nature Genetics
Open access127 authors |
Nov 2021 |
296 |
| 23 |
Colonoscopic full-thickness resection using an over-the-scope device: a prospective multicentre study in various indications
Arthur Robert Schmidt, Torsten Beyna, Brigitte M. Schumacher et al. · Gut
|
10 Aug 2017 |
295 |
| 24 |
Girls homozygous for an IL-2–inducible T cell kinase mutation that leads to protein deficiency develop fatal EBV-associated lymphoproliferation
Kirsten Huck, Oliver Feyen, Tim Niehues et al. · Journal of Clinical Investigation
Open access |
26 Mar 2009 |
293 |
| 25 |
German Association of Endocrine Surgeons practice guideline for the surgical management of malignant thyroid tumors
Henning Dralle et al. · Langenbeck s Archives of Surgery
|
Mar 2013 |
290 |
| 26 |
What to do and what not to do in serological diagnosis of pertussis: recommendations from EU reference laboratories
EU Pertstrain group, Nicole Guiso, Guy A. M. Berbers et al. · European Journal of Clinical Microbiology & Infectious Diseases
Open access |
10 Nov 2010 |
256 |
| 27 |
Regional citrate versus systemic heparin for anticoagulation in critically ill patients on continuous venovenous haemofiltration: a prospective randomized multicentre trial
Gerd Ruediger Hetzel, Martina Schmitz, H. Wissing et al. · Nephrology Dialysis Transplantation
Open access |
27 Sep 2010 |
255 |
| 28 |
Prophylactic Nasal Continuous Positive Airway Pressure Following Cardiac Surgery Protects From Postoperative Pulmonary Complications
Alexander Zarbock, Eckhard Mueller, Sabine Netzer et al. · CHEST Journal
|
19 Nov 2008 |
253 |
| 29 |
Pertussis Across the Globe
Tina Q. Tan, Tine Dalby, Kevin D. Forsyth et al. · The Pediatric Infectious Disease Journal
|
17 Jun 2015 |
240 |
| 30 |
International Society for Heart and Lung Transplantation Guidelines for the Evaluation and Care of Cardiac Transplant Candidates—2024
Yael Peled et al. · The Journal of Heart and Lung Transplantation
|
8 Aug 2024 |
230 |
| 31 |
Inflammation in atherosclerosis and psoriasis: common pathogenic mechanisms and the potential for an integrated treatment approach
Friedhelm Späh · British Journal of Dermatology
|
7 Aug 2008 |
224 |
| 32 |
Guidelines on the use of extracorporeal photopheresis
Robert Knobler et al. · Journal of the European Academy of Dermatology and Venereology
Open access |
19 Dec 2013 |
221 |
| 33 |
An Isoform of Ataxin‐3 Accumulates in the Nucleus of Neuronal Cells in Affected Brain Regions of SCA3 Patients
Thorsten Schmidt, G. Bernhard Landwehrmeyer, Ina Schmitt et al. · Brain Pathology
Open access |
Oct 1998 |
219 |
| 34 |
Hydrogen Sulfide Is a Novel Prosecretory Neuromodulator in the Guinea-Pig and Human Colon
Rudolf Schicho, Dagmar Krueger, Florian Zeller et al. · Gastroenterology
Open access |
21 Aug 2006 |
218 |
| 35 |
Spinal Cord Stimulation in Postherpetic Neuralgia and in Acute Herpes Zoster Pain
Henning Harke, Peter Gretenkort, Hans Ulrich Ladleif et al. · Anesthesia & Analgesia
|
Mar 2002 |
209 |
| 36 |
The extended clinical phenotype of 64 patients with dedicator of cytokinesis 8 deficiency
Karin R. Engelhardt et al. · Journal of Allergy and Clinical Immunology
Open access |
25 Feb 2015 |
199 |
| 37 |
Herpes zoster guideline11Established by an Expert Group on the occasion of a symposium on ‘Zoster and Zoster pain’ held on 9th December 2000 in Rostock (Germany) consisting of H. Schöfer, Frankfurt a. M.; S. Wassilew, Krefeld (Dermatology and Venereology); K. Friese (Gynaecology and Obstetrics); H.W. Pau (Otorhinolaryngology); A. Timm, R. Guthoff (Ophthalmology); A. Wree (Anatomy), Rostock; J.P. M
Gerd Gross, Helmut Schöfer, S. W. Wassilew et al. · Journal of Clinical Virology
|
15 Mar 2003 |
197 |
| 38 |
Prognostic Role and HER2 Expression of Circulating Tumor Cells in Peripheral Blood of Patients Prior to Radical Cystectomy: A Prospective Study
Michael Rink, Felix K.‐H. Chun, Roland Dahlem et al. · European Urology
|
27 Jan 2012 |
190 |
| 39 |
Percutaneous techniques versus surgical techniques for tracheostomy
Patrick Braß, Martin Hellmich, Angelika Ladra et al. · Cochrane Database of Systematic Reviews
Open access |
20 Jul 2016 |
189 |
| 40 |
EORTC consensus recommendations for the treatment of mycosis fungoides/Sézary syndrome – Update 2023
Johanna Latzka et al. · European Journal of Cancer
Open access |
18 Sep 2023 |
187 |
| 41 |
Aktualisierte Leitlinie zur Diagnostik und Therapie der Colitis ulcerosa 2011 – Ergebnisse einer Evidenzbasierten Konsensuskonferenz
Axel U. Dignass et al. · Zeitschrift für Gastroenterologie
Open access |
24 Aug 2011 |
179 |
| 42 |
Epidemiological Typing of Bordetella pertussis Isolates: Recommendations for a Standard Methodology
Frits R. Mooi, Hans O. Hallander, Carl Heinz Wirsing von König et al. · European Journal of Clinical Microbiology & Infectious Diseases
|
3 Apr 2000 |
178 |
| 43 |
Nucleic Acid Amplification Tests for Diagnosis of Bordetella Infections
Marion Riffelmann, Carl Heinz Wirsing von König, Valérie Caro et al. · Journal of Clinical Microbiology
Open access |
Oct 2005 |
178 |
| 44 |
Selective expression of histamine receptors H1R, H2R, and H4R, but not H3R, in the human intestinal tract
Leif Erik Sander, A Lorentz, G Sellge et al. · Gut
Open access |
18 Nov 2005 |
175 |
| 45 |
A worldwide survey on incidence, management, and prognosis of oesophageal fistula formation following atrial fibrillation catheter ablation: the POTTER-AF study
Roland Richard Tilz et al. · European Heart Journal
Open access |
16 Apr 2023 |
170 |
| 46 |
Clinical and immunological manifestations of patients with atypical severe combined immunodeficiency
Kerstin Felgentreff, Ruy Perez‐Becker, Carsten Speckmann et al. · Clinical Immunology
|
5 Jun 2011 |
165 |
| 47 |
Computed virtual chromoendoscopy versus standard colonoscopy with targeted indigocarmine chromoscopy: a randomised multicentre trial
J Pohl, E. Lotterer, Christoph Balzer et al. · Gut
|
6 Oct 2008 |
159 |
| 48 |
MR-guided laser-induced interstitial thermotherapy of recurrent glioblastoma multiforme: Preliminary results in 16 patients
Hans‐Joachim Schwarzmaier, Frank Eickmeyer, Wernholt von Tempelhoff et al. · European Journal of Radiology
|
19 Jul 2006 |
159 |
| 49 |
Recommendations are needed for adolescent and adult pertussis immunisation: rationale and strategies for consideration
M. Campins-Martı́, Hongtu Cheng, Kevin D. Forsyth et al. · Vaccine
|
Dec 2001 |
157 |
| 50 |
Strategies to Decrease Pertussis Transmission to Infants
Kevin D. Forsyth, Stanley Alan Plotkin, Tina Q. Tan et al. · PEDIATRICS
|
12 May 2015 |
157 |