Most cited papers from Hertie Foundation

Hertie Foundation

What are the most cited papers from Hertie Foundation?

The most cited paper from Hertie Foundation is "A three-dimensional human neural cell culture model of Alzheimer’s disease" (Se Hoon Choi, Young Hye Kim, Matthias Hebisch et al., 2014), with 1,235 citations. Next come "Fumaric acid esters exert neuroprotective effects in neuroinflammation via activation of the Nrf2 antioxidant pathway" (1,197) and "Debris clearance by microglia: an essential link between degeneration and regeneration" (1,156).

Published TypeFieldAccessCitations

Showing 50 of 60 papers. Every paper with more than 117 citations is listed.

Most cited papers, sortable by citations and release date
#	Paper
1	A three-dimensional human neural cell culture model of Alzheimer’s disease Se Hoon Choi, Young Hye Kim, Matthias Hebisch et al. · Nature Open access	10 Oct 2014	1,235
2	Fumaric acid esters exert neuroprotective effects in neuroinflammation via activation of the Nrf2 antioxidant pathway Ralf Andreas Linker, De-Hyung Lee, Sarah T. Ryan et al. · Brain	22 Feb 2011	1,197
3	Debris clearance by microglia: an essential link between degeneration and regeneration Harald Neumann, Mark Kotter, Robin J.M. Franklin · Brain Open access	20 Jun 2008	1,156
4	Clearance of apoptotic neurons without inflammation by microglial triggering receptor expressed on myeloid cells-2 Kazuya Takahashi, Christian D.P. Rochford, Harald Neumann · The Journal of Experimental Medicine Open access	21 Feb 2005	1,147
5	Inflammatory Cortical Demyelination in Early Multiple Sclerosis Claudia Francesca Lucchinetti, Bogdan Florin Gh. Popescu, Reem Fahd Bunyan et al. · New England Journal of Medicine Open access	7 Dec 2011	1,107
6	Understanding pathogenesis and therapy of multiple sclerosis via animal models: 70 years of merits and culprits in experimental autoimmune encephalomyelitis research Ralf Gold · Brain	22 Apr 2006	1,021
7	Copy number variation and selection during reprogramming to pluripotency Samer M. I. Hussein, Nizar N. Batada, Sanna Vuoristo et al. · Nature	Mar 2011	961
8	Differentiation block of oligodendroglial progenitor cells as a cause for remyelination failure in chronic multiple sclerosis Tanja Kuhlmann, Véronique E. Miron, Q. Cuo et al. · Brain Open access	30 May 2008	871
9	High cholesterol level is essential for myelin membrane growth Gesine Saher, Britta Brügger, Corinna Lappe-Siefke et al. · Nature Neuroscience	27 Mar 2005	812
10	IL-6R/STAT3/miR-34a feedback loop promotes EMT-mediated colorectal cancer invasion and metastasis Matjaž Rokavec, Meryem Gülfem Öner, Huihui Li et al. · Journal of Clinical Investigation Open access	18 Mar 2014	779
11	Effector T cell interactions with meningeal vascular structures in nascent autoimmune CNS lesions Ingo Bartholomäus, Naoto Kawakami, Francesca Odoardi et al. · Nature Open access	14 Oct 2009	687
12	A rosette-type, self-renewing human ES cell-derived neural stem cell with potential for in vitro instruction and synaptic integration Philipp J. Koch, Thoralf Opitz, Julius A. Steinbeck et al. · Proceedings of the National Academy of Sciences Open access	14 Feb 2009	506
13	Direct Conversion of Fibroblasts into Stably Expandable Neural Stem Cells Marc Christian Thier, Philipp Wörsdörfer, Yenal B. Lakes et al. · Cell stem cell Open access	22 Mar 2012	489
14	Sirt1 contributes critically to the redox-dependent fate of neural progenitors Timour Prozorovski, Ulf Schulze‐Topphoff, Robert Glumm et al. · Nature Cell Biology	16 Mar 2008	460
15	Axonal regulation of myelination by neuregulin 1 Klaus‐Armin Nave, James L. Salzer · Current Opinion in Neurobiology Review	8 Sep 2006	457
16	T cells become licensed in the lung to enter the central nervous system Francesca Odoardi, Christopher Sie, Kristina Streyl et al. · Nature Open access	Aug 2012	447
17	TREM2-Transduced Myeloid Precursors Mediate Nervous Tissue Debris Clearance and Facilitate Recovery in an Animal Model of Multiple Sclerosis Kazuya Takahashi, Marco Prinz, Massimiliano Stagi et al. · PLoS Medicine Open access	4 Apr 2007	421
18	Neuregulin-1/ErbB Signaling Serves Distinct Functions in Myelination of the Peripheral and Central Nervous System Bastian G. Brinkmann, Amit Agarwal, Michael Werner Sereda et al. · Neuron Open access	Aug 2008	418
19	Remyelination capacity of the MS brain decreases with disease chronicity THOMAS J. GOLDSCHMIDT, Jack Perry Antel, Fatima Barbara König et al. · Neurology	Jun 2009	413
20	Cargo‐dependent mode of uptake and bioavailability of TAT‐containing proteins and peptides in living cells Gisela Lättig-Tünnemann, Robert Montgomery Martin, Simone Haupt et al. · The FASEB Journal	28 Aug 2006	402
21	Effector T-cell trafficking between the leptomeninges and the cerebrospinal fluid Christian Schläger, Henrike Körner, Martin Wolfgang Krueger et al. · Nature Open access	Feb 2016	376
22	Capture of Neuroepithelial-Like Stem Cells from Pluripotent Stem Cells Provides a Versatile System for In Vitro Production of Human Neurons Anna Falk, Philipp J. Koch, Jaideep Kesavan et al. · PLoS ONE Open access	17 Jan 2012	367
23	Neuropsychiatric disease relevance of circulating anti-NMDA receptor autoantibodies depends on blood–brain barrier integrity Christian Hammer et al. · Molecular Psychiatry	3 Sep 2013	346
24	Small molecules enable highly efficient neuronal conversion of human fibroblasts Julia Ladewig, Jérôme Mertens, Jaideep Kesavan et al. · Nature Methods Open access	4 Apr 2012	321
25	Microglial clearance function in health and disease Isabella Napoli, Harald Neumann · Neuroscience	2 Jul 2008	321
26	Excitation-induced ataxin-3 aggregation in neurons from patients with Machado–Joseph disease Philipp J. Koch, Péter Breuer, Michael Peitz et al. · Nature	22 Nov 2011	311
27	Human-Induced Pluripotent Stem Cells form Functional Neurons and Improve Recovery After Grafting in Stroke-Damaged Brain Koichi Oki, Jemal Tatarishvili, James C. Wood et al. · Stem Cells Open access	11 Apr 2012	295
28	Epstein–Barr virus infection is not a characteristic feature of multiple sclerosis brain Simon N. Willis, Christine Stadelmann, Scott J. Rodig et al. · Brain Open access	28 Jul 2009	285
29	High-resolution DNA analysis of human embryonic stem cell lines reveals culture-induced copy number changes and loss of heterozygosity Elisa Närvä et al. · Nature Biotechnology	28 Mar 2010	283
30	Induction of Pluripotency in Adult Unipotent Germline Stem Cells Kinarm Ko, Natàlia Tàpia, Guangming Wu et al. · Cell stem cell Open access	Jul 2009	273
31	A 3D human neural cell culture system for modeling Alzheimer's disease Young Hye Kim, Se Hoon Choi, Carla D’Avanzo et al. · Nature Protocols Open access	11 Jun 2015	273
32	The lung microbiome regulates brain autoimmunity Leon Hosang, Roger Cugota Canals, Felicia Joy van der Flier et al. · Nature Open access	23 Feb 2022	265
33	Essential role of the microglial triggering receptor expressed on myeloid cells-2 (TREM2) for central nervous tissue immune homeostasis Harald Neumann, Kazuya Takahashi · Journal of Neuroimmunology	19 Jan 2007	252
34	Human induced pluripotent stem cell-derived cortical neurons integrate in stroke-injured cortex and improve functional recovery Daniel Tornero, Somsak Wattananit, Marita Grønning Madsen et al. · Brain Open access	21 Oct 2013	244
35	Exploring recombinant human erythropoietin in chronic progressive multiple sclerosis Hannelore Ehrenreich, Benjamin Fischer, Christine Norra et al. · Brain	29 Aug 2007	242
36	Inhibition of Notch Signaling in Human Embryonic Stem Cell–Derived Neural Stem Cells Delays G1/S Phase Transition and Accelerates Neuronal Differentiation In Vitro and In Vivo Lodovica Borghese, Dáša Doležalová, Thoralf Opitz et al. · Stem Cells	16 Mar 2010	238
37	Paraneoplastic stiff-person syndrome: passive transfer to rats by means of IgG antibodies to amphiphysin Claudia Sommer, Andreas Weishaupt, Jörg Brinkhoff et al. · The Lancet	Apr 2005	223
38	Sox2 Is Essential for Formation of Trophectoderm in the Preimplantation Embryo Maria Keramari, Janet Razavi, Karen A. Ingman et al. · PLoS ONE Open access	12 Nov 2010	208
39	Functional role of brain-derived neurotrophic factor in neuroprotective autoimmunity: therapeutic implications in a model of multiple sclerosis Ralf Andreas Linker, D.-H. Lee, Seray Demir et al. · Brain Open access	26 Jul 2010	206
40	Selective targeting of regulatory T cells with CD28 superagonists allows effective therapy of experimental autoimmune encephalomyelitis Niklas Beyersdorf, Stefanie Gaupp, Karen Balbach et al. · The Journal of Experimental Medicine Open access	Aug 2005	205
41	Peripheral T Cells Are the Therapeutic Targets of Glucocorticoids in Experimental Autoimmune Encephalomyelitis Simone Wüst, Jens van den Brandt, Denise Tischner et al. · The Journal of Immunology Open access	Jun 2008	182
42	Functional Integration of Embryonic Stem Cell-Derived Neurons In Vivo Marius Wernig, Felix Benninger, Tanja Schmandt et al. · Journal of Neuroscience Open access	2 Jun 2004	179
43	Effects of commissural de- and remyelination on motor skill behaviour in the cuprizone mouse model of multiple sclerosis David Liebetanz, Doron Merkler · Experimental Neurology	21 Jul 2006	163
44	Anticancer Effects of Niclosamide in Human Glioblastoma Anja Wieland et al. · Clinical Cancer Research	31 Jul 2013	161
45	Accumulation of tau induced in neurites by microglial proinflammatory mediators Philipp Gorlovoy, Sergey Larionov, Thao T. H. Pham et al. · The FASEB Journal	16 Mar 2009	154
46	Function of Neurotrophic Factors Beyond the Nervous System: Inflammation and Autoimmune Demyelination Ralf Andreas Linker, Ralf Gold, Fred Lühder · Critical Reviews in Immunology	2009	150
47	CNS-border associated macrophages respond to acute ischemic stroke attracting granulocytes and promoting vascular leakage Jordi Cuquet Pedragosa, Angélica Salas-Perdomo, Mattia Gallizioli et al. · Acta Neuropathologica Communications Open access	9 Aug 2018	149
48	Dietary cholesterol promotes repair of demyelinated lesions in the adult brain Stefan A. Berghoff, Nina Gerndt, Jan Winchenbach et al. · Nature Communications Open access	24 Jan 2017	149
49	Bystander Killing of Malignant Glioma by Bone Marrow–derived Tumor-Infiltrating Progenitor Cells Expressing a Suicide Gene Hrvoje Miletić, Yvonne Heidemarie Fischer, Sara A. Litwak et al. · Molecular Therapy Open access	15 May 2007	149
50	Reduction of voltage-operated potassium currents by levetiracetam: a novel antiepileptic mechanism of action? Michael Madeja, Doru Georg Margineanu, Ali Gorji et al. · Neuropharmacology	3 Sep 2003	148

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.