| 1 |
Everolimus in Postmenopausal Hormone-Receptor–Positive Advanced Breast Cancer
José Baselga et al. · New England Journal of Medicine
Open access |
7 Dec 2011 |
2,868 |
| 2 |
Overall Survival with Ribociclib plus Fulvestrant in Advanced Breast Cancer
Dennis J. Slamon et al. · New England Journal of Medicine
Open access |
11 Dec 2019 |
876 |
| 3 |
Extending Aromatase-Inhibitor Adjuvant Therapy to 10 Years
Paul Edward Goss, James N. Ingle, Kathleen I. Pritchard et al. · New England Journal of Medicine
Open access |
5 Jun 2016 |
656 |
| 4 |
MEK162 for patients with advanced melanoma harbouring NRAS or Val600 BRAF mutations: a non-randomised, open-label phase 2 study
Paolo A. Ascierto, Dirk Schadendorf, Carola Berking et al. · The Lancet Oncology
|
12 Feb 2013 |
647 |
| 5 |
Efficacy and Safety of Avelumab for Patients With Recurrent or Refractory Ovarian Cancer
Mary Lenora Disis, Matthew Hiram Taylor, Karen L. Kelly et al. · JAMA Oncology
Open access |
24 Jan 2019 |
437 |
| 6 |
Phase Ib Study of PEGylated Recombinant Human Hyaluronidase and Gemcitabine in Patients with Advanced Pancreatic Cancer
Sunil R. Hingorani, William Proctor Harris, Joseph Thaddeus Beck et al. · Clinical Cancer Research
Open access |
26 Jan 2016 |
330 |
| 7 |
Zoledronic Acid Inhibits Adjuvant Letrozole–Induced Bone Loss in Postmenopausal Women With Early Breast Cancer
Adam Brufsky, W. Graydon Harker, Joseph Thaddeus Beck et al. · Journal of Clinical Oncology
Open access |
12 Dec 2006 |
321 |
| 8 |
Ribociclib plus fulvestrant for postmenopausal women with hormone receptor-positive, human epidermal growth factor receptor 2-negative advanced breast cancer in the phase III randomized MONALEESA-3 trial: updated overall survival
Dennis J. Slamon, Patrick Neven, Stephen Chia et al. · Annals of Oncology
Open access |
5 Jun 2021 |
291 |
| 9 |
Prevention of everolimus-related stomatitis in women with hormone receptor-positive, HER2-negative metastatic breast cancer using dexamethasone mouthwash (SWISH): a single-arm, phase 2 trial
Hope S. Rugo, Lasika C. Seneviratne, Joseph Thaddeus Beck et al. · The Lancet Oncology
|
14 Mar 2017 |
230 |
| 10 |
TG4010 immunotherapy and first-line chemotherapy for advanced non-small-cell lung cancer (TIME): results from the phase 2b part of a randomised, double-blind, placebo-controlled, phase 2b/3 trial
Élisabeth Quoix et al. · The Lancet Oncology
|
22 Dec 2015 |
213 |
| 11 |
Final 5‐year results of Z‐FAST trial
Adam Brufsky, W. Graydon Harker, Joseph Thaddeus Beck et al. · Cancer
|
10 Oct 2011 |
192 |
| 12 |
A randomized adaptive phase II/III study of buparlisib, a pan-class I PI3K inhibitor, combined with paclitaxel for the treatment of HER2– advanced breast cancer (BELLE-4)
Miguel Martín, A. Chan, Luc Yves Dirix et al. · Annals of Oncology
Open access |
24 Oct 2016 |
186 |
| 13 |
Myelopreservation with the CDK4/6 inhibitor trilaciclib in patients with small-cell lung cancer receiving first-line chemotherapy: a phase Ib/randomized phase II trial
J.M. Weiss et al. · Annals of Oncology
Open access |
22 Aug 2019 |
174 |
| 14 |
PRONOUNCE: Randomized, Open-Label, Phase III Study of First-Line Pemetrexed + Carboplatin Followed by Maintenance Pemetrexed versus Paclitaxel + Carboplatin + Bevacizumab Followed by Maintenance Bevacizumab in Patients ith Advanced Nonsquamous Non–Small-Cell Lung Cancer
Ralph Zinner, Coleman K. Obasaju, David Robert Spigel et al. · Journal of Thoracic Oncology
Open access |
5 Nov 2014 |
173 |
| 15 |
A Phase IB multicentre dose‐determination study of BHQ 880 in combination with anti‐myeloma therapy and zoledronic acid in patients with relapsed or refractory multiple myeloma and prior skeletal‐related events
Swaminathan P. Iyer, Joseph Taddeus Beck, A. Keith Stewart et al. · British Journal of Haematology
Open access |
19 Aug 2014 |
157 |
| 16 |
Artificial Intelligence Tool for Optimizing Eligibility Screening for Clinical Trials in a Large Community Cancer Center
Joseph Thaddeus Beck, Melissa Rammage, Gretchen Purcell Jackson et al. · JCO Clinical Cancer Informatics
|
24 Jan 2020 |
133 |
| 17 |
Ribociclib plus letrozole in early breast cancer: A presurgical, window-of-opportunity study
Giuseppe Curigliano, Patricia Gómez Pardo, Funda Meric‐Bernstam et al. · The Breast
Open access |
20 Jun 2016 |
132 |
| 18 |
Myelopreservation with Trilaciclib in Patients Receiving Topotecan for Small Cell Lung Cancer: Results from a Randomized, Double-Blind, Placebo-Controlled Phase II Study
Lowell L. Hart, Renata Ferrarotto, Zoran Gojko Andric et al. · Advances in Therapy
Open access |
29 Oct 2020 |
125 |
| 19 |
Targeting the phosphatidylinositol 3-kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) pathway: An emerging treatment strategy for squamous cell lung carcinoma
Joseph Thaddeus Beck, Amen Ismail, Christina Tolomeo · Cancer Treatment Reviews
|
3 Jul 2014 |
119 |
| 20 |
Long‐term effects of crizotinib in ALK‐positive tumors (excluding NSCLC): A phase 1b open‐label study
Carlo B Gambacorti-Passerini, Sergey Orlov, Li Zhang et al. · American Journal of Hematology
Open access |
20 Jan 2018 |
114 |
| 21 |
Ribociclib plus letrozole versus letrozole alone in patients with de novo HR+, HER2− advanced breast cancer in the randomized MONALEESA-2 trial
Joyce O’Shaughnessy, Katarína Petráková, Gabe S. Sonke et al. · Breast Cancer Research and Treatment
Open access |
21 Nov 2017 |
113 |
| 22 |
Avelumab Plus Talazoparib in Patients With Advanced Solid Tumors
Timothy Anthony Yap, Aditya Bardia, Michael Dvorkin et al. · JAMA Oncology
Open access |
17 Nov 2022 |
109 |
| 23 |
Final overall survival analysis for the phase II RECORD-3 study of first-line everolimus followed by sunitinib versus first-line sunitinib followed by everolimus in metastatic RCC
Jennifer Jane Knox, Carlos H. Barrios, T.M. Kim et al. · Annals of Oncology
Open access |
21 Feb 2017 |
107 |
| 24 |
Health‐related quality of life of patients with advanced breast cancer treated with everolimus plus exemestane versus placebo plus exemestane in the phase 3, randomized, controlled, BOLERO‐2 trial
Howard A. Burris, Fabienne Lebrun, Hope S. Rugo et al. · Cancer
Open access |
15 Mar 2013 |
102 |
| 25 |
Safety and impact of dose reductions on efficacy in the randomised MONALEESA-2, -3 and -7 trials in hormone receptor-positive, HER2-negative advanced breast cancer
Howard A. Burris, Arlene Chan, Aditya Bardia et al. · British Journal of Cancer
Open access |
22 Jun 2021 |
94 |
| 26 |
A phase II, multicenter, open-label randomized study of motesanib or bevacizumab in combination with paclitaxel and carboplatin for advanced nonsquamous non-small-cell lung cancer
George R. Blumenschein, Fairooz F. Kabbinavar, Hari Menon et al. · Annals of Oncology
Open access |
15 Feb 2011 |
92 |
| 27 |
Abemaciclib in combination with pembrolizumab for HR+, HER2− metastatic breast cancer: Phase 1b study
Hope S. Rugo, Peter Kabos, Julia Beck et al. · npj Breast Cancer
Open access |
5 Nov 2022 |
91 |
| 28 |
Everolimus plus exemestane as first-line therapy in HR+, HER2− advanced breast cancer in BOLERO-2
Joseph Thaddeus Beck, Gabriel N. Hortobágyi, Mario Campone et al. · Breast Cancer Research and Treatment
Open access |
20 Dec 2013 |
88 |
| 29 |
Updated overall survival from the MONALEESA-3 trial in postmenopausal women with HR+/HER2− advanced breast cancer receiving first-line ribociclib plus fulvestrant
Patrick Neven, PA Fasching, Stephen Chia et al. · Breast Cancer Research
Open access |
31 Aug 2023 |
83 |
| 30 |
Randomized Phase II Trial of Pemetrexed Combined With Either Cisplatin or Carboplatin in Untreated Extensive-Stage Small-Cell Lung Cancer
Mark A. Socinski, Charles Weissman, Lowell L. Hart et al. · Journal of Clinical Oncology
|
18 Oct 2006 |
82 |
| 31 |
A randomized controlled phase III study of VB-111 combined with bevacizumab vs bevacizumab monotherapy in patients with recurrent glioblastoma (GLOBE)
Timothy Francis Cloughesy et al. · Neuro-Oncology
Open access |
7 Dec 2019 |
75 |
| 32 |
An open-label, phase II study of the polo-like kinase-1 (Plk-1) inhibitor, BI 2536, in patients with relapsed small cell lung cancer (SCLC)
Mark Magdi Awad, Q.S-C. Chu, Leena Gandhi et al. · Lung Cancer
|
30 Dec 2016 |
64 |
| 33 |
Barriers to dental care for children with autism spectrum disorder
S. Barry, E.A. O’Sullivan, Kyriacos Jack Toumba · European Archives of Paediatric Dentistry
|
13 Aug 2013 |
60 |
| 34 |
A phase 2 randomised study of veliparib plus FOLFIRI±bevacizumab versus placebo plus FOLFIRI±bevacizumab in metastatic colorectal cancer
Vera A. Gorbunova, Joseph Thaddeus Beck, Ralf‐Dieter Hofheinz et al. · British Journal of Cancer
Open access |
5 Dec 2018 |
58 |
| 35 |
Everolimus-based combination therapies for HR+, HER2− metastatic breast cancer
Joyce O’Shaughnessy, Joseph Thaddeus Beck, Melanie Royce · Cancer Treatment Reviews
Open access |
23 Jul 2018 |
57 |
| 36 |
A Randomized Phase II Study of Anti-CSF1 Monoclonal Antibody Lacnotuzumab (MCS110) Combined with Gemcitabine and Carboplatin in Advanced Triple-Negative Breast Cancer
Sherko Kuemmel et al. · Clinical Cancer Research
Open access |
6 Oct 2021 |
54 |
| 37 |
Overall survival (OS) results of the phase III MONALEESA-3 trial of postmenopausal patients (pts) with hormone receptor-positive (HR+), human epidermal growth factor 2-negative (HER2−) advanced breast cancer (ABC) treated with fulvestrant (FUL) ± ribociclib (RIB)
Dennis J. Slamon, Patrick Neven, Stephen Chia et al. · Annals of Oncology
Open access |
Oct 2019 |
54 |
| 38 |
First-line ribociclib plus letrozole in postmenopausal women with HR+ , HER2− advanced breast cancer: Tumor response and pain reduction in the phase 3 MONALEESA-2 trial
Wolfgang Janni, Emilio Alba, Thomas Bachelot et al. · Breast Cancer Research and Treatment
|
5 Feb 2018 |
52 |
| 39 |
Ublituximab plus ibrutinib versus ibrutinib alone for patients with relapsed or refractory high-risk chronic lymphocytic leukaemia (GENUINE): a phase 3, multicentre, open-label, randomised trial
Jeff Porter Sharman, Danielle M. Brander, Anthony R. Mato et al. · The Lancet Haematology
|
23 Feb 2021 |
50 |
| 40 |
A Phase Ib, open-label, dose-finding study of alpelisib in combination with paclitaxel in patients with advanced solid tumors
Jordi A. Rodon, Giuseppe Curigliano, Jean‐Pierre Delord et al. · Oncotarget
Open access |
3 Aug 2018 |
50 |
| 41 |
Phase 1B/2 study of the HSP90 inhibitor AUY922 plus trastuzumab in metastatic HER2-positive breast cancer patients who have progressed on trastuzumab-based regimen
Anthony H. Kong, Daniel William Rea, Samreen I. Ahmed et al. · Oncotarget
Open access |
25 Apr 2016 |
49 |
| 42 |
A Phase Ib/II Study of the JAK1 Inhibitor, Itacitinib, plus nab-Paclitaxel and Gemcitabine in Advanced Solid Tumors
Gregory Lawrence Beatty, Safi Shahda, Thaddeus Beck et al. · The Oncologist
Open access |
16 Aug 2018 |
47 |
| 43 |
Severe Histoplasmosis in Travelers to Nicaragua
Michelle S. Weinberg, Julia Weeks, Susan E. Lance-Parker et al. · Emerging infectious diseases
Open access |
Oct 2003 |
46 |
| 44 |
Imlunestrant, an Oral Selective Estrogen Receptor Degrader, as Monotherapy and in Combination With Targeted Therapy in Estrogen Receptor–Positive, Human Epidermal Growth Factor Receptor 2–Negative Advanced Breast Cancer: Phase Ia/Ib EMBER Study
Komal L. Jhaveri et al. · Journal of Clinical Oncology
Open access |
6 Sep 2024 |
45 |
| 45 |
Neoadjuvant Talazoparib in Patients With Germline BRCA1/2 Mutation-Positive, Early-Stage Triple-Negative Breast Cancer: Results of a Phase II Study
Jennifer Keating Litton, Joseph Thaddeus Beck, Jason Michael Jones et al. · The Oncologist
Open access |
15 Jun 2023 |
45 |
| 46 |
Planting Date, Cultivar, and Tillage System Effects on Dryland Soybean Production
Michael P. Popp, T. C. Keisling, Ronald W. McNew et al. · Agronomy Journal
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2002 |
44 |
| 47 |
Inkblot Perception and Personality: The Holtzman Inkblot Technique
Raymond J. McCall, Wayne H. Holtzman, Joseph S. Thorpe et al. · The American Journal of Psychology
|
Dec 1964 |
44 |
| 48 |
A Phase II Trial of Prexasertib (LY2606368) in Patients With Extensive-Stage Small-Cell Lung Cancer
Lauren A. Byers, Alejandro Navarro, Eric Scott Schaefer et al. · Clinical Lung Cancer
Open access |
24 Apr 2021 |
42 |
| 49 |
Early Evidence of Anabolic Bone Activity of BHQ880, a Fully Human Anti-DKK1 Neutralizing Antibody: Results of a Phase 2 Study in Previously Untreated Patients with Smoldering Multiple Myeloma At Risk for Progression
Nikhil C. Munshi, Rafat Abonour, Joseph Thaddeus Beck et al. · Blood
|
16 Nov 2012 |
40 |
| 50 |
Ribociclib plus fulvestrant for advanced breast cancer: Health-related quality-of-life analyses from the MONALEESA-3 study
Peter Andreas Fasching, Joseph Thaddeus Beck, Arlene Chan et al. · The Breast
Open access |
23 Sep 2020 |
38 |