| 1 |
The Unified Protocol for Transdiagnostic Treatment of Emotional Disorders Compared With Diagnosis-Specific Protocols for Anxiety Disorders
David Harrison Barlow, Todd J. Farchione, Jacqueline R. Bullis et al. · JAMA Psychiatry
Open access |
2 Aug 2017 |
863 |
| 2 |
Randomized controlled trial of a 12-week digital care program in improving low back pain
Raad Shebib, Jeannie F. Bailey, Peter Smittenaar et al. · npj Digital Medicine
Open access |
28 Dec 2018 |
367 |
| 3 |
Insomnia disorder: State of the science and challenges for the future
Dieter Wilhelm Riemann, Fee Benz, Raphael J. Dressle et al. · Journal of Sleep Research
Open access |
22 Apr 2022 |
342 |
| 4 |
Reduced Leaflet Motion after Transcatheter Aortic-Valve Replacement
Ole De Backer et al. · New England Journal of Medicine
Open access |
16 Nov 2019 |
289 |
| 5 |
The association of insomnia disorder characterised by objective short sleep duration with hypertension, diabetes and body mass index: A systematic review and meta-analysis
Keith A. Johnson, Christopher James Gordon, Julia L. Chapman et al. · Sleep Medicine Reviews
Review |
23 Jan 2021 |
171 |
| 6 |
A randomized controlled trial of digital cognitive behavioral therapy for insomnia in pregnant women
David A. Kalmbach, Philip Cheng, Louise Margaret O'Brien et al. · Sleep Medicine
Open access |
21 Mar 2020 |
163 |
| 7 |
Digital Care for Chronic Musculoskeletal Pain: 10,000 Participant Longitudinal Cohort Study
Jeannie F. Bailey, Vibhu Agarwal, Patricia Z. Zheng et al. · Journal of Medical Internet Research
Open access |
21 Mar 2020 |
123 |
| 8 |
Effects of a 12-Week Digital Care Program for Chronic Knee Pain on Pain, Mobility, and Surgery Risk: Randomized Controlled Trial
Gabriel Mecklenburg, Peter Smittenaar, Jennifer C. Erhart‐Hledik et al. · Journal of Medical Internet Research
Open access |
25 Apr 2018 |
114 |
| 9 |
The complex relationship between body mass index and response to immune checkpoint inhibition in metastatic melanoma patients
Douglas MacArthur Donnelly, Shirin Bajaj, Jae-Hong Yu et al. · Journal for ImmunoTherapy of Cancer
Open access |
19 Aug 2019 |
105 |
| 10 |
The clinical effects of sleep restriction therapy for insomnia: A meta-analysis of randomised controlled trials
Leonie Maurer, Jules Schneider, Christopher B. Miller et al. · Sleep Medicine Reviews
Review |
21 Apr 2021 |
102 |
| 11 |
C reactive protein impairs adaptive immunity in immune cells of patients with melanoma
Tatsuya Yoshida, Junya Ichikawa, Iulia Giuroiu et al. · Journal for ImmunoTherapy of Cancer
Open access |
Apr 2020 |
101 |
| 12 |
Epidural Interventions in the Management of Chronic Spinal Pain: American Society of Interventional Pain Physicians (ASIPP) Comprehensive Evidence-Based Guidelines
Laxmaiah Manchikanti et al. · Scholarly Commons (University of the Pacific)
Open access |
2021 |
95 |
| 13 |
Efficacy of digital cognitive behavioral therapy for moderate‐to‐severe symptoms of generalized anxiety disorder: A randomized controlled trial
Jenna R. Carl, Christopher B. Miller, Alasdair L. Henry et al. · Depression and Anxiety
Open access |
29 Jul 2020 |
94 |
| 14 |
Childbearing, Infertility, and Career Trajectories Among Women in Medicine
Jennifer Bender Bakkensen, Kathryn S. Smith, Elaine O. Cheung et al. · JAMA Network Open
Open access |
27 Jul 2023 |
87 |
| 15 |
BERT-XML: Large Scale Automated ICD Coding Using BERT Pretraining
Zachariah Zhang, Jingshu Liu, Narges Razavian
Conference paperOpen access |
2020 |
82 |
| 16 |
HDAC6 selective inhibition of melanoma patient T-cells augments anti-tumor characteristics
Andressa S. Laino, Brian Christopher Betts, Anandharaman Veerapathran et al. · Journal for ImmunoTherapy of Cancer
Open access |
6 Feb 2019 |
82 |
| 17 |
Applying a Community Violence Framework to Understand the Impact of Immigration Enforcement Threat on Latino Children
Rita Gabriela Barajas-Gonzalez, Cecilia Ayón, Franco Torres · Child Policy Nexus
Open access |
2018 |
81 |
| 18 |
Carotid web: an occult mechanism of embolic stroke
Brian Mac Grory, Bart J. Emmer, Stefan D. Roosendaal et al. · Journal of Neurology Neurosurgery & Psychiatry
Open access |
Oct 2020 |
79 |
| 19 |
The Sleep Condition Indicator: reference values derived from a sample of 200 000 adults
Colin Alexander Espie, Pedro Farias Machado, Jenna R. Carl et al. · Journal of Sleep Research
Open access |
29 Nov 2017 |
76 |
| 20 |
Cost-effectiveness of digital cognitive behavioral therapy ( Sleepio ) for insomnia: a Markov simulation model in the United States
Michael Darden, Colin Alexander Espie, Jenna R. Carl et al. · SLEEP
|
5 Nov 2020 |
73 |
| 21 |
Potential Intended and Unintended Consequences of Recommending Initiation of Colorectal Cancer Screening at Age 45 Years
Peter S. Liang, James E. Allison, Uri Ladabaum et al. · Gastroenterology
|
20 Aug 2018 |
70 |
| 22 |
Insomnia as a mediating therapeutic target for depressive symptoms: A sub‐analysis of participant data from two large randomized controlled trials of a digital sleep intervention
Alasdair L. Henry, Christopher B. Miller, Richard A Emsley et al. · Journal of Sleep Research
Open access |
18 Aug 2020 |
67 |
| 23 |
Insomnia symptoms and their association with workplace productivity: cross-sectional and pre-post intervention analyses from a large multinational manufacturing company
Colin Alexander Espie, Brent Pawlecki, Dickon Waterfield et al. · Sleep Health
|
23 Apr 2018 |
67 |
| 24 |
Insomnia, depression, and anxiety symptoms interact and individually impact functioning: A network and relative importance analysis in the context of insomnia
H. Ariel Bard, Ciarán O’Driscoll, Christopher B. Miller et al. · Sleep Medicine
Open access |
8 Dec 2022 |
63 |
| 25 |
Patterns of Ownership and Usage of Wearable Devices in the United States, 2020-2022: Survey Study
Ashwini Nagappan, Adriana Krasniansky, Madelyn Knowles · Journal of Medical Internet Research
Open access |
26 Jul 2024 |
60 |
| 26 |
Assessing the Clinical Robustness of Digital Health Startups: Cross-sectional Observational Analysis
Sean Day, Veeraj Shah, Sari Kaganoff et al. · Journal of Medical Internet Research
Open access |
20 Jun 2022 |
60 |
| 27 |
Improving productivity, costs and environmental impact in International Eye Health Services: using the ‘Eyefficiency’ cataract surgical services auditing tool to assess the value of cataract surgical services
Hena Goel, Thomas Alan Wemyss, Tanya Harris et al. · BMJ Open Ophthalmology
Open access |
May 2021 |
59 |
| 28 |
Treatment with Zinc is Associated with Reduced In-Hospital Mortality Among COVID-19 Patients: A Multi-Center Cohort Study
Jennifer Ann Frontera, Joseph Rahimian, Shadi R. Yaghi et al.
PreprintOpen access |
26 Oct 2020 |
59 |
| 29 |
Redefined Measure of Early Neurological Improvement Shows Treatment Benefit of Alteplase Over Placebo
Shashank Agarwal, Erica Scher, Aaron Sylvan Lord et al. · Stroke
Open access |
18 Mar 2020 |
59 |
| 30 |
Primary Palliative Care for Emergency Medicine (PRIM-ER): Protocol for a Pragmatic, Cluster-Randomised, Stepped Wedge Design to Test the Effectiveness of Primary Palliative Care Education, Training and Technical Support for Emergency Medicine
Corita R. Grudzen, Abraham A. Brody, Frank R. Chung et al. · BMJ Open
Open access |
Jul 2019 |
59 |
| 31 |
Patient-Reported Outcome Measures in Dermatology: A Systematic Review
Rachael Pattinson, N Trialonis-Suthakharan, Sunnia Gupta et al. · Acta Dermato Venereologica
ReviewOpen access |
2021 |
57 |
| 32 |
Development of a Single-Session, Transdiagnostic Preventive Intervention for Young Adults at Risk for Emotional Disorders
Kate H. Bentley, Hannah T. Boettcher, Jacqueline R. Bullis et al. · Behavior Modification
Open access |
13 Oct 2017 |
56 |
| 33 |
Regulating digital therapeutics for mental health: Opportunities, challenges, and the essential role of psychologists
Jenna R. Carl, Deborah J. Jones, Oliver J. Lindhiem et al. · British Journal of Clinical Psychology
|
Mar 2021 |
54 |
| 34 |
The effect of sleep restriction therapy for insomnia on sleep pressure and arousal: a randomized controlled mechanistic trial
Leonie Maurer, Colin Alexander Espie, Ximena Omlin et al. · SLEEP
|
31 Aug 2021 |
52 |
| 35 |
Immunotherapy to treat malignancy in patients with pre-existing autoimmunity
Patrick McKay Boland, Anna C. Pavlick, Jeffrey S. Weber et al. · Journal for ImmunoTherapy of Cancer
Open access |
Apr 2020 |
51 |
| 36 |
Standalone middle meningeal artery embolization versus middle meningeal artery embolization with concurrent surgical evacuation for chronic subdural hematomas: a multicenter propensity score matched analysis of clinical and radiographic outcomes
Huanwen Alvin Chen et al. · Journal of NeuroInterventional Surgery
|
6 Nov 2023 |
50 |
| 37 |
Gastric Carcinomas With Lymphoid Stroma
Erika Marie. Hissong, Girish Ramrattan, Pan Zhang et al. · The American Journal of Surgical Pathology
|
13 Feb 2018 |
50 |
| 38 |
Impact of autoimmune rheumatic diseases on birth outcomes: a population-based study
Jennifer Strouse, Brittney M. Donovan, Munazza Tamkeen Fatima et al. · RMD Open
Open access |
Apr 2019 |
49 |
| 39 |
Implementation and early adaptation of patient-reported outcome measures into an electronic health record: A technical report
Heather Taffet Gold, Raj J. Karia, Alissa P. Link et al. · Health Informatics Journal
Open access |
5 Dec 2018 |
48 |
| 40 |
The lncRNA LUCAT1 is elevated in inflammatory disease and restrains inflammation by regulating the splicing and stability of NR4A2
Tim Vierbuchen, Shiuli Agarwal, John L. Johnson et al. · Proceedings of the National Academy of Sciences
Open access |
28 Dec 2022 |
47 |
| 41 |
Neurophotonic Tools for Microscopic Measurements and Manipulation: Status Report
Ahmed S. Abdelfattah et al. · Neurophotonics
Open access |
27 Apr 2022 |
46 |
| 42 |
SARS-CoV-2 genomic characterization and clinical manifestation of the COVID-19 outbreak in Uruguay
Victoria Elizondo et al. · Emerging Microbes & Infections
Open access |
12 Dec 2020 |
45 |
| 43 |
Disseminating cognitive behavioural therapy ( CBT ) for insomnia at scale: capitalising on the potential of digital CBT to deliver clinical guideline care
Colin Alexander Espie, Alasdair L. Henry · Journal of Sleep Research
Open access |
29 Aug 2023 |
44 |
| 44 |
Feasibility and efficacy of a digital CBT intervention for symptoms of Generalized Anxiety Disorder: A randomized multiple-baseline study
Christopher B. Miller, Jenny Gu, Alasdair L. Henry et al. · Journal of Behavior Therapy and Experimental Psychiatry
|
7 Sep 2020 |
44 |
| 45 |
Gut microbiome dysbiosis during COVID-19 is associated with increased risk for bacteremia and microbial translocation.
Mericien Venzon et al. · Research Square
PreprintOpen access |
27 Jul 2021 |
43 |
| 46 |
Rigorous and rapid evidence assessment in digital health with the evidence DEFINED framework
Jordan Silberman et al. · npj Digital Medicine
Open access |
31 May 2023 |
41 |
| 47 |
Diurnal and seasonal variation in psoriasis symptoms
Felicity J. Ferguson, Georgia Lada, Hamish J. A. Hunter et al. · Journal of the European Academy of Dermatology and Venereology
Open access |
28 Jun 2020 |
41 |
| 48 |
Understanding the Impact of Image Quality and Distance of Objects to Object Detection Performance
Hao Yu, Haoyang Pei, Yixuan Lyu et al.
Conference paper |
Oct 2023 |
39 |
| 49 |
Does adjunctive digital CBT for insomnia improve clinical outcomes in an improving access to psychological therapies service?
Richard B. Stott, John Pimm, Richard A Emsley et al. · Behaviour Research and Therapy
Open access |
Jul 2021 |
38 |
| 50 |
Evidence‐informed is not enough: digital therapeutics also need to be evidence‐based
Colin Alexander Espie, Joseph Firth, John Blake Torous · World Psychiatry
Open access |
7 May 2022 |
36 |