| 1 |
Sugar-mimic glycosidase inhibitors: natural occurrence, biological activity and prospects for therapeutic application
Naoki Asano, Robert J. Nash, Russell J. Molyneux et al. · Tetrahedron Asymmetry
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May 2000 |
1,012 |
| 2 |
Glycosidase inhibitors: update and perspectives on practical use
Naoki Asano · Glycobiology
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10 Jun 2003 |
718 |
| 3 |
Novel splice variants of the receptor for advanced glycation end-products expressed in human vascular endothelial cells and pericytes, and their putative roles in diabetes-induced vascular injury
Hideto Yonekura, Yasuhiko Yamamoto, Shigeru Sakurai et al. · Biochemical Journal
Open access |
12 Mar 2003 |
716 |
| 4 |
Polyhydroxylated alkaloids — natural occurrence and therapeutic applications
Alison A. Watson, George W. J. Fleet, Naoki Asano et al. · Phytochemistry
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Feb 2001 |
708 |
| 5 |
Accelerated transport and maturation of lysosomal α–galactosidase A in Fabry lymphoblasts by an enzyme inhibitor
Jianqiang Fan, Satoshi Ishii, Naoki Asano et al. · Nature Medicine
|
1999 |
617 |
| 6 |
Favipiravir, an anti-influenza drug against life-threatening RNA virus infections
Kimíyasu Shiraki, Tohru Daikoku · Pharmacology & Therapeutics
Open access |
22 Feb 2020 |
583 |
| 7 |
Development and prevention of advanced diabetic nephropathy in RAGE-overexpressing mice
Yasuhiko Yamamoto, Ichiro Kato, Toshio Doi et al. · Journal of Clinical Investigation
Open access |
15 Jul 2001 |
476 |
| 8 |
Polyhydroxylated Alkaloids Isolated from Mulberry Trees (Morus alba L.) and Silkworms (Bombyx mori L.)
Naoki Asano, Toru Yamashita, Kayo Yasuda et al. · Journal of Agricultural and Food Chemistry
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16 Aug 2001 |
389 |
| 9 |
Expression of short-chain fatty acid receptor GPR41 in the human colon
Hideaki Tazoe, Yasuko Otomo, Shin-ichiro Karaki et al. · Biomedical Research
Open access |
2009 |
336 |
| 10 |
Identification of cytochrome P450 enzymes responsible for metabolism of cannabidiol by human liver microsomes
Rongrong Jiang, Satoshi Yamaori, Shuso Takeda et al. · Life Sciences
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26 Jun 2011 |
320 |
| 11 |
Advanced Glycation End Product-induced Apoptosis and Overexpression of Vascular Endothelial Growth Factor and Monocyte Chemoattractant Protein-1 in Human-cultured Mesangial Cells
Sho‐ichi Yamagishi, Yosuke Inagaki, Tamami Okamoto et al. · Journal of Biological Chemistry
Open access |
Jun 2002 |
312 |
| 12 |
N-containing sugars fromMorus alba and their glycosidase inhibitory activities
Naoki Asano, Kengo Oseki, Emiko Tomioka et al. · Carbohydrate Research
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Jun 1994 |
276 |
| 13 |
Atherosclerosis and Extracellular Matrix
Shogo Katsuda, Toshiyuki Kaji · Journal of Atherosclerosis and Thrombosis
Open access |
2003 |
273 |
| 14 |
Angiogenesis induced by advanced glycation end products and its prevention by cerivastatin
Tamami Okamoto, Sho‐ichi Yamagishi, Yosuke Inagaki et al. · The FASEB Journal
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4 Oct 2002 |
258 |
| 15 |
Immunohistochemical distribution of the receptor for advanced glycation end products in neurons and astrocytes in Alzheimer’s disease
Nobuyuki Sasaki, Sadamu Toki, Hiroshi Chowei et al. · Brain Research
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2001 |
255 |
| 16 |
RAGE Control of Diabetic Nephropathy in a Mouse Model
K.M. Myint, Yasuhiko Yamamoto, Toshio Doi et al. · Diabetes
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25 Aug 2006 |
248 |
| 17 |
Convolutamydine A, a novel bioactive hydroxyoxindole alkaloid from marine bryozoan Amathia convoluta
Yoshiaki Kamano, Huiping Zhang, Yoshitatsu Ichihara et al. · Tetrahedron Letters
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Apr 1995 |
247 |
| 18 |
In vitro inhibition and intracellular enhancement of lysosomal α‐galactosidase A activity in Fabry lymphoblasts by 1‐deoxygalactonojirimycin and its derivatives
Naoki Asano, Satoshi Ishii, Haruhisa Kizu et al. · European Journal of Biochemistry
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Jul 2000 |
244 |
| 19 |
Cytochrome P450 enzymes involved in the metabolism of tetrahydrocannabinols and cannabinol by human hepatic microsomes
Kazuhito Watanabe, Satoshi Yamaori, Tatsuya Funahashi et al. · Life Sciences
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18 Jan 2007 |
239 |
| 20 |
Improvement of serum aminotransferase levels after phlebotomy in patients with chronic active hepatitis C and excess hepatic iron.
Hisao Hayashi, Toshikuni Takikawa, N Nishimura et al. · PubMed
|
Jul 1994 |
228 |
| 21 |
Potent inhibition of human cytochrome P450 3A isoforms by cannabidiol: Role of phenolic hydroxyl groups in the resorcinol moiety
Satoshi Yamaori, Juri Ebisawa, Yoshimi Okushima et al. · Life Sciences
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27 Feb 2011 |
223 |
| 22 |
Possible Involvement of Advanced Glycation End-Products (AGEs) in the Pathogenesis of Alzheimers Disease
Masayoshi Takeuchi, Sho‐ichi Yamagishi · Current Pharmaceutical Design
|
Apr 2008 |
221 |
| 23 |
Pigment Epithelium-derived Factor Inhibits Advanced Glycation End Product-induced Retinal Vascular Hyperpermeability by Blocking Reactive Oxygen Species-mediated Vascular Endothelial Growth Factor Expression
Sho‐ichi Yamagishi, Kazuo Nakamura, Takanori Matsui et al. · Journal of Biological Chemistry
Open access |
18 May 2006 |
218 |
| 24 |
Sugars with nitrogen in the ring isolated from the leaves of Morus bombycis
Naoki Asano, Emiko Tomioka, Haruhisa Kizu et al. · Carbohydrate Research
|
Feb 1994 |
213 |
| 25 |
Advanced Glycation End Products-Induced Apoptosis and Overexpression of Vascular Endothelial Growth Factor in Bovine Retinal Pericytes
Sho‐ichi Yamagishi, Shinjiro Amano, Yosuke Inagaki et al. · Biochemical and Biophysical Research Communications
|
2002 |
211 |
| 26 |
Hyperglycemia induces oxidative and nitrosative stress and increases renal functional impairment in Nrf2‐deficient mice
Keigyou Yoh, Aki Hirayama, Kazusa Ishizaki et al. · Genes to Cells
Open access |
9 Oct 2008 |
207 |
| 27 |
Neurotoxicity of Advanced Glycation End-Products for Cultured Cortical Neurons
Masayoshi Takeuchi, Richard Bucala, Takako Suzuki et al. · Journal of Neuropathology & Experimental Neurology
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Dec 2000 |
202 |
| 28 |
Cannabidiol Is a Potent Inhibitor of the Catalytic Activity of Cytochrome P450 2C19
Rongrong Jiang, Satoshi Yamaori, Yasuka Okamoto et al. · Drug Metabolism and Pharmacokinetics
|
2013 |
199 |
| 29 |
Immunological Evidence that Non-carboxymethyllysine Advanced Glycation End-products Are Produced from Short Chain Sugars and Dicarbonyl Compounds in vivo
Masayoshi Takeuchi, Zenji Makita, Richard Bucala et al. · Molecular Medicine
Open access |
Feb 2000 |
197 |
| 30 |
Atypical antipsychotics suppress production of proinflammatory cytokines and up-regulate interleukin-10 in lipopolysaccharide-treated mice
Haruhiko Sugino, Takashi Futamura, Yasuhide Mitsumoto et al. · Progress in Neuro-Psychopharmacology and Biological Psychiatry
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25 Dec 2008 |
196 |
| 31 |
Elevated levels of serum advanced glycation end products in patients with non‐alcoholic steatohepatitis
Hideyuki Hyogo, Sho‐ichi Yamagishi, Keiko Iwamoto et al. · Journal of Gastroenterology and Hepatology
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7 Jun 2007 |
192 |
| 32 |
Biological Properties of d - and l -1-Deoxyazasugars
Atsushi Kato, Noriko Kato, Erika Kano et al. · Journal of Medicinal Chemistry
Open access |
18 Sep 2004 |
187 |
| 33 |
TAGE (Toxic AGEs) Theory in Diabetic Complications
Takashi Sato, Mina Iwaki, Noriko Shimogaito et al. · Current Molecular Medicine
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29 Apr 2006 |
183 |
| 34 |
Naturally Occurring Iminosugars and Related Compounds: Structure, Distribution, and Biological Activity
Naoki Asano · Current Topics in Medicinal Chemistry
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Feb 2003 |
181 |
| 35 |
Two genetic variants of CD38 in subjects with autism spectrum disorder and controls
Toshio Munesue et al. · Neuroscience Research
Open access |
3 May 2010 |
176 |
| 36 |
Glucagon-like peptide-1 (GLP-1) inhibits advanced glycation end product (AGE)-induced up-regulation of VCAM-1 mRNA levels in endothelial cells by suppressing AGE receptor (RAGE) expression
Yuji Ishibashi, Takanori Matsui, Masayoshi Takeuchi et al. · Biochemical and Biophysical Research Communications
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23 Dec 2009 |
172 |
| 37 |
Pigment epithelium-derived factor protects cultured retinal pericytes from advanced glycation end product-induced injury through its antioxidative properties
Sho‐ichi Yamagishi, Yosuke Inagaki, Shinjiro Amano et al. · Biochemical and Biophysical Research Communications
|
Aug 2002 |
171 |
| 38 |
Nitrogen-in-the-Ring Pyranoses and Furanoses: Structural Basis of Inhibition of Mammalian Glycosidases
Naoki Asano, Kengo Oseki, Haruhisa Kizu et al. · Journal of Medicinal Chemistry
Open access |
Oct 1994 |
168 |
| 39 |
Valiolamine, a new .ALPHA.-glucosidase inhibiting aminocyclitol produced by Streptomyces hygroscopicus.
Yukihiko Kameda, Naoki Asano, Michiyo Yoshikawa et al. · The Journal of Antibiotics
Open access |
1984 |
166 |
| 40 |
Characterization of major phytocannabinoids, cannabidiol and cannabinol, as isoform-selective and potent inhibitors of human CYP1 enzymes
Satoshi Yamaori, Mika Kushihara, Ikuo Yamamoto et al. · Biochemical Pharmacology
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2 Feb 2010 |
164 |
| 41 |
Design and Synthesis of Highly Potent and Selective Pharmacological Chaperones for the Treatment of Gaucher's disease
Philippe Compain, Olivier R. Martin, Charlotte Boucheron et al. · ChemBioChem
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26 Jul 2006 |
163 |
| 42 |
Atorvastatin decreases serum levels of advanced glycation endproducts (AGEs) in nonalcoholic steatohepatitis (NASH) patients with dyslipidemia: clinical usefulness of AGEs as a biomarker for the attenuation of NASH
Yuki Kimura, Hideyuki Hyogo, Sho‐ichi Yamagishi et al. · Journal of Gastroenterology
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29 Jan 2010 |
160 |
| 43 |
Advanced glycation end products attenuate cellular insulin sensitivity by increasing the generation of intracellular reactive oxygen species in adipocytes
Hiroyuki Unoki‐Kubota, Hideaki Bujo, Sho‐ichi Yamagishi et al. · Diabetes Research and Clinical Practice
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14 Nov 2006 |
157 |
| 44 |
Serum levels of non-carboxymethyllysine advanced glycation endproducts are correlated to severity of microvascular complications in patients with Type 1 diabetes
Junnosuke Miura, Sho‐ichi Yamagishi, Yasuko Uchigata et al. · Journal of Diabetes and its Complications
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30 Dec 2002 |
157 |
| 45 |
Use of floating alginate gel beads for stomach-specific drug delivery
Yojiro Murata · European Journal of Pharmaceutics and Biopharmaceutics
|
Sep 2000 |
156 |
| 46 |
Diagnostic Accuracy of 123I-Meta-Iodobenzylguanidine Myocardial Scintigraphy in Dementia with Lewy Bodies: A Multicenter Study
Mitsuhiro Yoshita et al. · PLoS ONE
Open access |
20 Mar 2015 |
154 |
| 47 |
New polyhydroxylated pyrrolizidine alkaloids from Muscari armeniacum: structural determination and biological activity
Naoki Asano, Hiroyo Kuroi, Kyoko Ikeda et al. · Tetrahedron Asymmetry
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2000 |
151 |
| 48 |
Cannabidiol, a Major Phytocannabinoid, As a Potent Atypical Inhibitor for CYP2D6
Satoshi Yamaori, Yasuka Okamoto, Ikuo Yamamoto et al. · Drug Metabolism and Disposition
|
5 Aug 2011 |
150 |
| 49 |
Advanced glycation end products inhibit de novo protein synthesis and induce TGF-β overexpression in proximal tubular cells
Sho‐ichi Yamagishi, Yosuke Inagaki, Tamami Okamoto et al. · Kidney International
Open access |
Feb 2003 |
150 |
| 50 |
Antihyperglycemic Effects of N-Containing Sugars from Xanthocercis zambesiaca, Morus bombycis, Aglaonema treubii, and Castanospermum australe in Streptozotocin-Diabetic Mice
Hiroshi Nojima, Ikuko Kimura, Fujun Chen et al. · Journal of Natural Products
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20 Feb 1998 |
149 |