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Most cited papers from Hoshi University

What are the most cited papers from Hoshi University?

The most cited paper from Hoshi University is "Encapsulation of Hydrophilic and Lipophilic Drugs in PLGA Nanoparticles by the Nanoprecipitation Method" (José Mário Barichello, Mariko Morishita, Kozo Takayama et al., 1999), with 544 citations. Next come "Direct Involvement of Orexinergic Systems in the Activation of the Mesolimbic Dopamine Pathway and Related Behaviors Induced by Morphine" (522) and "Is the oral route possible for peptide and protein drug delivery?" (516).

Showing 50 of 61 papers. Every paper with more than 173 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Encapsulation of Hydrophilic and Lipophilic Drugs in PLGA Nanoparticles by the Nanoprecipitation Method José Mário Barichello, Mariko Morishita, Kozo Takayama et al. · Drug Development and Industrial Pharmacy 1999 544
2 Direct Involvement of Orexinergic Systems in the Activation of the Mesolimbic Dopamine Pathway and Related Behaviors Induced by Morphine Minoru Narita, Yasuyuki Nagumo, Seiko Hashimoto et al. · Journal of Neuroscience Open access 11 Jan 2006 522
3 Is the oral route possible for peptide and protein drug delivery? Mariko Morishita, Nicholas A. Peppas · Drug Discovery Today 8 Sep 2006 516
4 Biodegradation and distribution of water-soluble chitosan in mice Hiraku Onishi, Yoshiharu Machida · Biomaterials 1999 488
5 Pyrroloindolone Synthesis via a Cp*CoIII-Catalyzed Redox-Neutral Directed C–H Alkenylation/Annulation Sequence Hideya Ikemoto, Tatsuhiko Yoshino, Ken Sakata et al. · Journal of the American Chemical Society 20 Mar 2014 463
6 Perfluorooctane Sulfonate (PFOS) and Related Perfluorinated Compounds in Human Maternal and Cord Blood Samples: Assessment of PFOS Exposure in a Susceptible Population during Pregnancy Kōichi Inoue, Fumio Okada, Rie Ito et al. · Environmental Health Perspectives Open access 13 Apr 2004 458
7 Antioxidative and Anti-Glycation Activity of Garcinol fromGarcinia indicaFruit Rind Fumio Yamaguchi, Toshiaki Ariga, Yoshihiro Yoshimura et al. · Journal of Agricultural and Food Chemistry 15 Jan 2000 452
8 Impaired Insulin Signaling in Endothelial Cells Reduces Insulin-Induced Glucose Uptake by Skeletal Muscle Tetsuya Kubota et al. · Cell Metabolism Open access Mar 2011 444
9 Current challenges in non-invasive insulin delivery systems: A comparative review El‐Sayed Khafagy, Mariko Morishita, Yoshinori Onuki et al. · Advanced Drug Delivery Reviews Review 23 Aug 2007 436
10 Determination of mRNA Expression of Human UDP-Glucuronosyltransferases and Application for Localization in Various Human Tissues by Real-Time Reverse Transcriptase-Polymerase Chain Reaction Shuji Ohno, Shizuo Nakajin · Drug Metabolism and Disposition 7 Oct 2008 428
11 Oral delivery of insulin using pH‐responsive complexation gels Anthony M. Lowman, Mariko Morishita, Masako Kajita et al. · Journal of Pharmaceutical Sciences Sep 1999 406
12 Epigenetic mechanisms of chronic pain Giannina Descalzi, Daigo Ikegami, Toshikazu Ushijima et al. · Trends in Neurosciences ReviewOpen access 9 Mar 2015 404
13 Ligand-binding specificities of laminin-binding integrins: A comprehensive survey of laminin–integrin interactions using recombinant α3β1, α6β1, α7β1 and α6β4 integrins Ritsuo Nishiuchi, Junichi Takagi, Maria Hayashi et al. · Matrix Biology 19 Jan 2006 393
14 BAS1 : A gene regulating brassinosteroid levels and light responsiveness in Arabidopsis Michael M. Neff, Serena M. Nguyen, Elizabeth J. Malancharuvil et al. · Proceedings of the National Academy of Sciences Open access 21 Dec 1999 386
15 Decreased Serum Free Testosterone in Workers Exposed to High Levels of Di- n -butyl Phthalate (DBP) and Di-2-ethylhexyl Phthalate (DEHP): A Cross-Sectional Study in China Guowei Pan, Tomoyuki Hanaoka, Mariko Yoshimura et al. · Environmental Health Perspectives Open access 27 Jul 2006 352
16 Role of Lysophosphatidylcholine (LPC) in Atherosclerosis Takayuki Matsumoto, Tsuneo Kobayashi, Katsuo Kamata · Current Medicinal Chemistry 29 Nov 2007 318
17 Application of Chitin and Chitosan Derivatives in the Pharmaceutical Field Yoshinori Katō, Hiraku Onishi, Yoshiharu Machida · Current Pharmaceutical Biotechnology Oct 2003 301
18 Dehydrative Direct CH Allylation with Allylic Alcohols under [Cp*CoIII] Catalysis Yudai Suzuki, Bo Sun, Ken Sakata et al. · Angewandte Chemie International Edition Jul 2015 301
19 Correlations between Prenatal Exposure to Perfluorinated Chemicals and Reduced Fetal Growth Noriaki Washino, Yasuaki Saijo, Seiko Sasaki et al. · Environmental Health Perspectives Open access 2 Nov 2008 295
20 Impairment of endothelium‐dependent relaxation and changes in levels of cyclic GMP in aorta from streptozotocin‐induced diabetic rats Katsuo Kamata, Noriyuki Miyata, Yutaka Kasuya · British Journal of Pharmacology Open access Jun 1989 291
21 Chronic Pain Induces Anxiety with Concomitant Changes in Opioidergic Function in the Amygdala Minoru Narita, Chihiro Kaneko, Kan Miyoshi et al. · Neuropsychopharmacology 10 Aug 2005 288
22 Antitumor Agents. 217. Curcumin Analogues as Novel Androgen Receptor Antagonists with Potential as Anti-Prostate Cancer Agents Hironori Ohtsu, Zhiyan Xiao, Junko Ishida et al. · Journal of Medicinal Chemistry 12 Oct 2002 268
23 Exosome-Like Vesicles with Dipeptidyl Peptidase IV in Human Saliva Yuko Ogawa, Masami Kanai‐Azuma, Yoshihiro Akimoto et al. · Biological and Pharmaceutical Bulletin Open access 2008 259
24 Proteomic Analysis of Two Types of Exosomes in Human Whole Saliva Yuko Ogawa, Yuri Miura, Akira Harazono et al. · Biological and Pharmaceutical Bulletin Open access 2011 256
25 Preparation and characterization of superparamagnetic iron oxide nanoparticles stabilized by alginate Huili Ma, Xian Qi, Yoshie Maitani et al. · International Journal of Pharmaceutics 10 Oct 2006 246
26 Copper-Catalyzed Enantioselective Propargylic Amination of Propargylic Esters with Amines: Copper−Allenylidene Complexes as Key Intermediates Gaku Hattori, Ken Sakata, Hiroshi Matsuzawa et al. · Journal of the American Chemical Society 9 Jul 2010 245
27 Sex difference of cytochrome P-450 in the rat: Purification, characterization, and quantitation of constitutive forms of cytochrome P-450 from liver microsomes of male and female rats Tetsuya Kamataki, Kaori Maeda, Yasushi Yamazoe et al. · Archives of Biochemistry and Biophysics Sep 1983 234
28 Absorption of insulin from Pluronic F-127 gels following subcutaneous administration in rats José Mário Barichello, Mariko Morishita, Kozo Takayama et al. · International Journal of Pharmaceutics Jul 1999 234
29 Hypertension, hypertriglyceridemia, and impaired endothelium-dependent vascular relaxation in mice lacking insulin receptor substrate-1. Hideki Abe, N Yamada, Katsuo Kamata et al. · Journal of Clinical Investigation Open access 15 Apr 1998 230
30 Determination of bisphenol A in human serum by high-performance liquid chromatography with multi-electrode electrochemical detection Kōichi Inoue, Kayoko Kato, Yoshihiro Yoshimura et al. · Journal of Chromatography B Biomedical Sciences and Applications Nov 2000 221
31 Direct Evidence of Astrocytic Modulation in the Development of Rewarding Effects Induced by Drugs of Abuse Minoru Narita, Minoru Narita, Mayumi Miyatake et al. · Neuropsychopharmacology 11 Jan 2006 219
32 Stability of microcystins from cyanobacteria—II. Effect of UV light on decomposition and isomerization Kiyomi Tsuji, Tomohiko Watanuki, Fumio Kondo et al. · Toxicon Dec 1995 215
33 Novel stir bar sorptive extraction methods for environmental and biomedical analysis Migaku Kawaguchi, Rie Ito, Koichi Saito et al. · Journal of Pharmaceutical and Biomedical Analysis 20 Oct 2005 211
34 Antipruritic activity of the κ-opioid receptor agonist, TRK-820 Yuko Togashi, Hideo Umeuchi, Kiyoshi Okano et al. · European Journal of Pharmacology 2002 208
35 The Translation Inhibitor Rocaglamide Targets a Bimolecular Cavity between eIF4A and Polypurine RNA Shintaro Iwasaki, W. Iwasaki, Mari Takahashi et al. · Molecular Cell Open access 27 Dec 2018 206
36 Enhanced intracellular delivery and improved antitumor efficacy of doxorubicin by sterically stabilized liposomes modified with a synthetic RGD mimetic Xiao-Bing Xiong, Yue Huang, Wan-Liang Lü et al. · Journal of Controlled Release 26 Aug 2005 205
37 Measurement of cellular 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) reduction activity and lactate dehydrogenase release using MTT Kazuho Abe, Norio Matsuki · Neuroscience Research Dec 2000 202
38 Molecular evolution of the ribonuclease superfamily Jaap J. Beintema, Cornelis SCHÜLLER, Masachika IRIE et al. · Progress in Biophysics and Molecular Biology Open access 1988 202
39 Antioxidative Effect of Maillard Reaction Products Using Glucose−Glycine Model System Yoshihiro Yoshimura, Tsutomu Iijima, Takaho Watanabe et al. · Journal of Agricultural and Food Chemistry Oct 1997 201
40 Circulating mitochondrial DNA and Toll-like receptor 9 are associated with vascular dysfunction in spontaneously hypertensive rats Cameron G. McCarthy, Camilla Ferreira Wenceslau, Styliani Goulopoulou et al. · Cardiovascular Research Open access 24 Apr 2015 197
41 Determination of bisphenol A in canned vegetables and fruit by high performance liquid chromatography Terumitsu Yoshida, Masakazu Horie, Youji Hoshino et al. · Food Additives & Contaminants 2001 197
42 Epigenetic transcriptional activation of monocyte chemotactic protein 3 contributes to long-lasting neuropathic pain Satoshi Imai et al. · Brain Open access 30 Jan 2013 194
43 New mucosal dosage form of insulin. Masami Ishida, Yoshiharu Machida, Naoki Nambu et al. · Chemical and Pharmaceutical Bulletin Open access 1981 194
44 The effect of water-soluble polymers on drug-cyclodextrin complexation Þorsteinn Loftsson, Hafrún Frikdriksdóttir, Anna M. Sigurkdardóttir et al. · International Journal of Pharmaceutics Sep 1994 192
45 Identification of an anthocyanin occurring in some red wines Johanna Bakker, Peter Bridle, Toshio Honda et al. · Phytochemistry Apr 1997 192
46 Novel oral insulin delivery systems based on complexation polymer hydrogels: Single and multiple administration studies in type 1 and 2 diabetic rats Mariko Morishita, Takahiro Goto, Koji Nakamura et al. · Journal of Controlled Release Open access 3 Dec 2005 191
47 Liposomes as Carriers for Topical and Transdermal Delivery Elka Touítou, Hans E. Junginger, N. Weiner et al. · Journal of Pharmaceutical Sciences Sep 1994 190
48 Regulations of opioid dependence by opioid receptor types Minoru Narita, Masahiko Funada, Tsutomu Suzuki · Pharmacology & Therapeutics 2001 190
49 Down-Regulation of miR-133a Contributes to Up-Regulation of RhoA in Bronchial Smooth Muscle Cells Yoshihiko Chiba, Miki Tanabe, Kumiko Goto et al. · American Journal of Respiratory and Critical Care Medicine 30 Jul 2009 189
50 Free Radical Scavenging Activity and Antiulcer Activity of Garcinol fromGarcinia indicaFruit Rind Fumio Yamaguchi, Makoto Saito, Toshiaki Ariga et al. · Journal of Agricultural and Food Chemistry 19 May 2000 188

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.