Most cited papers from Hospital de León

Hospital de León

What are the most cited papers from Hospital de León?

The most cited paper from Hospital de León is "A Comparison of Four Methods of Weaning Patients from Mechanical Ventilation" (Andrés Esteban, Fernando Frutos–Vivar, Martin J. Tobin et al., 1995), with 1,575 citations. Next come "Definition and Diagnostic Criteria for Sarcopenic Obesity: ESPEN and EASO Consensus Statement" (968) and "The ALIEN study: incidence and outcome of acute respiratory distress syndrome in the era of lung protective ventilation" (607).

Published TypeFieldAccessAuthorsCitations

Showing 50 of 60 papers. Every paper with more than 126 citations is listed.

Most cited papers, sortable by citations and release date
#	Paper
1	A Comparison of Four Methods of Weaning Patients from Mechanical Ventilation Andrés Esteban, Fernando Frutos–Vivar, Martin J. Tobin et al. · New England Journal of Medicine	9 Feb 1995	1,575
2	Definition and Diagnostic Criteria for Sarcopenic Obesity: ESPEN and EASO Consensus Statement Lorenzo M. Donini et al. · Obesity Facts Open access	2022	968
3	The ALIEN study: incidence and outcome of acute respiratory distress syndrome in the era of lung protective ventilation on behalf of the ALIEN Network, Jesús Villar, Jesús Blanco et al. · Intensive Care Medicine Open access	14 Oct 2011	607
4	Secondary prevention in the clinical management of patients with cardiovascular diseases. Core components, standards and outcome measures for referral and delivery Massimo Francesco Piepoli, Ugo Corrà, Stamatis N. Adamopoulos et al. · European Journal of Preventive Cardiology Open access	20 Jun 2012	604
5	Incidence, organ dysfunction and mortality in severe sepsis: a Spanish multicentre study Jesús Blanco, Arturo Muriel-Bombín, Víctor Sagredo-Meneses et al. · Critical Care Open access	17 Dec 2008	536
6	Exome sequencing identifies MAX mutations as a cause of hereditary pheochromocytoma Iñaki Comino‐Méndez et al. · Nature Genetics Open access	19 Jun 2011	531
7	Multiparameter flow cytometric remission is the most relevant prognostic factor for multiple myeloma patients who undergo autologous stem cell transplantation Bruno Paiva et al. · Blood Open access	31 Jul 2008	480
8	Routine invasive strategy within 24 hours of thrombolysis versus ischaemia-guided conservative approach for acute myocardial infarction with ST-segment elevation (GRACIA-1): a randomised controlled trial Francisco Fernández‐Avilés, Joaquín J. Alonso, Alfonso Castro‐Beiras et al. · The Lancet	Sep 2004	419
9	Ribonucleotide Reductase Messenger RNA Expression and Survival in Gemcitabine/Cisplatin-Treated Advanced Non-Small Cell Lung Cancer Patients Rafael Rosell, Kathleen D. Danenberg, Vincente Alberola et al. · Clinical Cancer Research Open access	15 Feb 2004	359
10	Drug-Eluting Stent Thrombosis José M. de la Torre-Hernández, Fernándo Alfonso, Felipe Hernández et al. · Journal of the American College of Cardiology Open access	Mar 2008	312
11	An Early PEEP/F i O2 Trial Identifies Different Degrees of Lung Injury in Patients with Acute Respiratory Distress Syndrome Jesús Villar, Lina Pérez‐Méndez, J. Cristobal López et al. · American Journal of Respiratory and Critical Care Medicine	21 Jun 2007	295
12	Intervertebral disc, sensory nerves and neurotrophins: who is who in discogenic pain? José García‐Cosamalón, Miguel del Valle Soto, Marta G. Calavia et al. · Journal of Anatomy Open access	28 Apr 2010	281
13	Androgen receptor gene status in plasma DNA associates with worse outcome on enzalutamide or abiraterone for castration-resistant prostate cancer: a multi-institution correlative biomarker study Vincenza Conteduca et al. · Annals of Oncology Open access	31 Mar 2017	274
14	Individualised perioperative open-lung approach versus standard protective ventilation in abdominal surgery (iPROVE): a randomised controlled trial Carlos Ferrando et al. · The Lancet Respiratory Medicine Open access152 authors	19 Jan 2018	268
15	Cytogenetic risk stratification in chronic myelomonocytic leukemia Esperanza Such et al. · Haematologica Open access	25 Nov 2010	265
16	Endogenous Cardiac Stem Cell Activation by Insulin-Like Growth Factor-1/Hepatocyte Growth Factor Intracoronary Injection Fosters Survival and Regeneration of the Infarcted Pig Heart Georgina M. Ellison, Daniele Torella, Santo Dellegrottaglie et al. · Journal of the American College of Cardiology Open access	5 Jul 2011	250
17	Clinical Impact of Intravascular Ultrasound Guidance in Drug-Eluting Stent Implantation for Unprotected Left Main Coronary Disease José M. de la Torre Hernández, José Antonio Baz Alonso, Fernando Alfonso Manterola et al. · JACC: Cardiovascular Interventions Open access	Mar 2014	240
18	Inhibition of VEGF expression through blockade of Hif1α and STAT3 signalling mediates the anti-angiogenic effect of melatonin in HepG2 liver cancer cells Sara Carbajo‐Pescador, Raquel Ordóñez, Marta Benet et al. · British Journal of Cancer Open access	11 Jun 2013	234
19	Treatment of Refractory Uveitis with Adalimumab: A Prospective Multicenter Study of 131 Patients Manuel Díaz-Llopis, David Salom, Carmen García-De-Vicuña et al. · Ophthalmology Open access	21 Apr 2012	233
20	Sildenafil for improving outcomes in patients with corrected valvular heart disease and persistent pulmonary hypertension: a multicenter, double-blind, randomized clinical trial Javier Bermejo et al. · European Heart Journal Open access	14 Nov 2017	231
21	Epidermal growth factor receptor activating mutations in Spanish gefitinib-treated non-small-cell lung cancer patients H. Cortés-Funes et al. · Annals of Oncology Open access	26 Apr 2005	231
22	Predictors of Device-Related Thrombus Following Percutaneous Left Atrial Appendage Occlusion Trevor Simard et al. · Journal of the American College of Cardiology Open access	Jul 2021	226
23	An overview of animal models for investigating the pathogenesis and therapeutic strategies in acute hepatic failure María Jesús Tuñón, Marcelino Alvarez, Jesús M Culebras et al. · World Journal of Gastroenterology Open access	2009	212
24	Research Resource: Transcriptional Profiling Reveals Different Pseudohypoxic Signatures in SDHB and VHL-Related Pheochromocytomas Elena Ana López-Jiménez et al. · Molecular Endocrinology Open access	28 Oct 2010	211
25	Fecal Gluten Peptides Reveal Limitations of Serological Tests and Food Questionnaires for Monitoring Gluten-Free Diet in Celiac Disease Patients Isabel Comino et al. · The American Journal of Gastroenterology Open access	20 Sep 2016	210
26	Exercise Prescription in Patients with Different Combinations of Cardiovascular Disease Risk Factors: A Consensus Statement from the EXPERT Working Group Dominique Hansen et al. · Sports Medicine Open access	4 May 2018	201
27	PD-L1/PD-1 presence in the tumor microenvironment and activity of PD-1 blockade in multiple myeloma Bruno Paiva, Arantza Azpilikueta, Noemí Puig et al. · Leukemia	17 Mar 2015	191
28	Long-Term Benefit of Early Pre-Reperfusion Metoprolol Administration in Patients With Acute Myocardial Infarction Gonzalo Pizarro et al. · Journal of the American College of Cardiology Open access	30 Mar 2014	189
29	Differences of small intestinal bacteria populations in adults and children with/without celiac disease: Effect of age, gluten diet, and disease Esther Nistal, Alberto Caminero, Alexandra R. Herrán et al. · Inflammatory Bowel Diseases	8 Aug 2011	189
30	Association Between Use of Enhanced Recovery After Surgery Protocol and Postoperative Complications in Total Hip and Knee Arthroplasty in the Postoperative Outcomes Within Enhanced Recovery After Surgery Protocol in Elective Total Hip and Knee Arthroplasty Study (POWER2) Javier Ripollés‐Melchor et al. · JAMA Surgery Open access	12 Feb 2020	188
31	Worldwide Survey of COVID-19–Associated Arrhythmias Ellie J. Coromilas et al. · Circulation Arrhythmia and Electrophysiology Open access	8 Feb 2021	183
32	Development and Validation of Hepamet Fibrosis Scoring System–A Simple, Noninvasive Test to Identify Patients With Nonalcoholic Fatty Liver Disease With Advanced Fibrosis Javier Ampuero et al. · Clinical Gastroenterology and Hepatology Open access	10 Jun 2019	183
33	Impacto de la pandemia de COVID-19 sobre la actividad asistencial en cardiología intervencionista en España Oriol Rodríguez‐Leor, Belén A. Cid-Álvarez, Soledad Ojeda et al. · REC, Interventional cardiology Open access	Apr 2020	179
34	Elite Athletes Live Longer Than the General Population: A Meta-Analysis Nuria Garatachea, Alejandro Santos‐Lozano, Fabián Sanchis‐Gomar et al. · Mayo Clinic Proceedings Review	12 Aug 2014	174
35	Primary angioplasty vs. early routine post-fibrinolysis angioplasty for acute myocardial infarction with ST-segment elevation: the GRACIA-2 non-inferiority, randomized, controlled trial Francisco Fernández‐Avilés, Joaquín J. Alonso, Gonzalo Peña et al. · European Heart Journal	23 Jan 2007	173
36	Analysis of the immune system of multiple myeloma patients achieving long-term disease control by multidimensional flow cytometry Roberto JP Magalhaes et al. · Haematologica Open access	6 Jul 2012	172
37	R-ESHAP as salvage therapy for patients with relapsed or refractory diffuse large B-cell lymphoma: the influence of prior exposure to rituximab on outcome. A GEL/TAMO study Alejandro Martı́n, Eva Conde, Montserrat Arnán et al. · Haematologica Open access	22 Oct 2008	172
38	Differences in faecal bacteria populations and faecal bacteria metabolism in healthy adults and celiac disease patients Esther Nistal, Alberto Caminero, Santiago Vivas et al. · Biochimie	20 Apr 2012	171
39	Ustekinumab for the Treatment of Refractory Crohnʼs Disease Sam Khorrami, Daniel Ginard, Ignacio Marín‐Jiménez et al. · Inflammatory Bowel Diseases Open access	15 Jun 2016	167
40	Serine/threonine protein phosphatases PP1 and PP2A are key players in apoptosis Alphonse Garcı́a, Xavier Cayla, Julien Guergnon et al. · Biochimie	Aug 2003	163
41	Incidence, associated factors and clinical impact of severe infections in a large, multicentric cohort of patients with systemic lupus erythematosus Íñigo Rúa‐Figueroa et al. · Seminars in Arthritis and Rheumatism Open access	27 Jan 2017	162
42	Customized Treatment in Non-Small-Cell Lung Cancer Based on EGFR Mutations and BRCA1 mRNA Expression Rafael Rosell et al. · PLoS ONE Open access	4 May 2009	162
43	Different exosome cargo from plasma/bronchoalveolar lavage in non‐small‐cell lung cancer Marta Rodríguez, Javier Silva, Ana López‐Alfonso et al. · Genes Chromosomes and Cancer	25 Apr 2014	159
44	Terahertz imaging for early screening of diabetic foot syndrome: A proof of concept Goretti G. Hernandez-Cardoso, S. C. Rojas-Landeros, Mariana Alfaro-Gómez et al. · Scientific Reports Open access	6 Feb 2017	158
45	Abatacept in patients with rheumatoid arthritis and interstitial lung disease: A national multicenter study of 63 patients Carlos Fernández-Díaz et al. · Seminars in Arthritis and Rheumatism Open access	6 Jan 2018	155
46	Cardiovascular disease in familial hypercholesterolaemia: Influence of low-density lipoprotein receptor mutation type and classic risk factors Rodrigo Alonso, Nelva Mata, Sergio Castillo et al. · Atherosclerosis	22 Feb 2008	155
47	Treatment Strategies in Primary Vitreoretinal Lymphoma Anjo Riemens et al. · JAMA Ophthalmology Open access	20 Nov 2014	154
48	Diversity of the cultivable human gut microbiome involved in gluten metabolism: isolation of microorganisms with potential interest for coeliac disease Alberto Caminero, Alexandra R. Herrán, Esther Nistal et al. · FEMS Microbiology Ecology Open access	6 Feb 2014	154
49	Acute myeloid leukemia in the older adults Antonio Medina Almeida, Fernando Ramos · Leukemia Research Reports Open access	2016	150
50	Persistence of microscopic human cancers in mice: alterations in the angiogenic balance accompanies loss of tumor dormancy Taturo Udagawa, António Fernández, Eike‐Gert Achilles et al. · The FASEB Journal	30 Aug 2002	150

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.