| 1 |
GSVA: gene set variation analysis for microarray and RNA-Seq data
Sonja Hänzelmann, Robert Castelo, Justin Guinney · BMC Bioinformatics
Open access |
16 Jan 2013 |
17,089 |
| 2 |
Analysis of protein-coding genetic variation in 60,706 humans
Monkol Lek et al. · Nature
Open access |
Aug 2016 |
10,439 |
| 3 |
The mutational constraint spectrum quantified from variation in 141,456 humans
Konrad J. Karczewski et al. · Nature
Open access177 authors |
27 May 2020 |
10,422 |
| 4 |
The size and burden of mental disorders and other disorders of the brain in Europe 2010
Hans‐Ulrich Wïttchen, Frank Jacobi, Jürgen T. Rehm et al. · European Neuropsychopharmacology
Open access |
Sep 2011 |
3,849 |
| 5 |
Arterial embolisation or chemoembolisation versus symptomatic treatment in patients with unresectable hepatocellular carcinoma: a randomised controlled trial
Josep Maria Llovet, María Isabel Real, Xavier Montañá et al. · The Lancet
|
May 2002 |
3,526 |
| 6 |
COSMIN guideline for systematic reviews of patient-reported outcome measures
C.A.C. Prinsen, Lidwine Brigitta Mokkink, L.M. Bouter et al. · Quality of Life Research
ReviewOpen access |
12 Feb 2018 |
3,453 |
| 7 |
Revised International Prognostic Scoring System for Myelodysplastic Syndromes
Peter L. Greenberg et al. · Blood
Open access |
28 Jun 2012 |
3,195 |
| 8 |
Human papillomavirus genotype attribution in invasive cervical cancer: a retrospective cross-sectional worldwide study
Silvia de Sanjosé et al. · The Lancet Oncology
|
18 Oct 2010 |
2,774 |
| 9 |
WHO World Mental Health Surveys International College Student Project: Prevalence and distribution of mental disorders.
Randy Patrick Auerbach, WHO WMH-ICS Collaborators, Philippe Mortier et al. · Journal of Abnormal Psychology
Open access |
13 Sep 2018 |
2,552 |
| 10 |
Childhood adversities and adult psychopathology in the WHO World Mental Health Surveys
Ronald C. Kessler et al. · The British Journal of Psychiatry
Open access |
29 Oct 2010 |
2,532 |
| 11 |
Cross-national epidemiology of DSM-IV major depressive episode
Evelyn J. Bromet et al. · BMC Medicine
Open access |
26 Jul 2011 |
2,275 |
| 12 |
Transcriptome and genome sequencing uncovers functional variation in humans
Tuuli Lappalainen et al. · Nature
Open access |
Sep 2013 |
2,200 |
| 13 |
EAU Guidelines on Prostate Cancer. Part 1: Screening, Diagnosis, and Local Treatment with Curative Intent—Update 2013
Axel Heidenreich, Patrick J. Bastian, Joaquim Bellmunt et al. · European Urology
|
6 Oct 2013 |
1,951 |
| 14 |
The global burden of mental disorders: An update from the WHO World Mental Health (WMH) Surveys
Ronald C. Kessler, Sergio Aguilar‐Gaxiola, Jordi Alonso et al. · Epidemiologia e Psichiatria Sociale
Open access |
Mar 2009 |
1,951 |
| 15 |
TGFβ drives immune evasion in genetically reconstituted colon cancer metastasis
Daniele V. F. Tauriello, Sergio Palomo‐Ponce, Diana Stork et al. · Nature
|
Feb 2018 |
1,880 |
| 16 |
Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes
Rainer Malik et al. · Nature Genetics
Open access428 authors |
12 Mar 2018 |
1,753 |
| 17 |
Cost of disorders of the brain in Europe 2010
Anders Gustavsson et al. · European Neuropsychopharmacology
Open access |
15 Sep 2011 |
1,753 |
| 18 |
Trauma and PTSD in the WHO World Mental Health Surveys
Ronald C. Kessler et al. · European Journal of Psychotraumatology
Open access |
31 Jul 2017 |
1,659 |
| 19 |
A Short Screener Is Valid for Assessing Mediterranean Diet Adherence among Older Spanish Men and Women
Helmut Schröder, Montserrat Fitó, Ramón Estruch et al. · Journal of Nutrition
Open access |
20 Apr 2011 |
1,645 |
| 20 |
Drinking Water Nitrate and Human Health: An Updated Review
Mary H. Ward, Rena R. Jones, Jean D. Brender et al. · International Journal of Environmental Research and Public Health
Open access |
23 Jul 2018 |
1,577 |
| 21 |
A Comparison of Four Methods of Weaning Patients from Mechanical Ventilation
Andrés Esteban, Fernando Frutos–Vivar, Martin J. Tobin et al. · New England Journal of Medicine
|
9 Feb 1995 |
1,575 |
| 22 |
Whole-genome landscapes of major melanoma subtypes
Nicholas K. Hayward et al. · Nature
Open access |
May 2017 |
1,548 |
| 23 |
Prediction of Postoperative Pulmonary Complications in a Population-based Surgical Cohort
Jaume Canet, L. Gallart, Carmen Guiralt Gomar et al. · Anesthesiology
Open access |
2 Nov 2010 |
1,518 |
| 24 |
EAU Guidelines on Prostate Cancer. Part 1: Screening, Diagnosis, and Treatment of Clinically Localised Disease
Axel Heidenreich, Joaquim Bellmunt, M. Bolla et al. · European Urology
|
29 Oct 2010 |
1,498 |
| 25 |
Targeting metastasis-initiating cells through the fatty acid receptor CD36
Gloria Pascual, Alexandra Avgustinova, Stefania Mejetta et al. · Nature
|
5 Dec 2016 |
1,468 |
| 26 |
A genomic mutational constraint map using variation in 76,156 human genomes
Siwei Chen et al. · Nature
Open access238 authors |
6 Dec 2023 |
1,453 |
| 27 |
Posttraumatic stress disorder in the World Mental Health Surveys
Karestan Chase Koenen et al. · Psychological Medicine
Open access |
7 Apr 2017 |
1,446 |
| 28 |
Barriers to mental health treatment: results from the WHO World Mental Health surveys
Laura Helena Andrade et al. · Psychological Medicine
Open access |
9 Aug 2013 |
1,372 |
| 29 |
EAU Guidelines on Prostate Cancer. Part II: Treatment of Advanced, Relapsing, and Castration-Resistant Prostate Cancer
Axel Heidenreich, Patrick J. Bastian, Joaquim Bellmunt et al. · European Urology
|
12 Nov 2013 |
1,361 |
| 30 |
Development of Land Use Regression Models for PM 2.5 , PM 2.5 Absorbance, PM 10 and PM coarse in 20 European Study Areas; Results of the ESCAPE Project
Marloes Eeftens et al. · Environmental Science & Technology
Open access |
10 Sep 2012 |
1,285 |
| 31 |
Long-term management of moderate-to-severe atopic dermatitis with dupilumab and concomitant topical corticosteroids (LIBERTY AD CHRONOS): a 1-year, randomised, double-blinded, placebo-controlled, phase 3 trial
Andrew Blauvelt et al. · The Lancet
Open access |
4 May 2017 |
1,269 |
| 32 |
Beneficial effects of long-term intravenous iron therapy with ferric carboxymaltose in patients with symptomatic heart failure and iron deficiency
Piotr P. Ponikowski, Dirk J. van Veldhuisen, Josep Comín‐Colet et al. · European Heart Journal
Open access |
31 Aug 2014 |
1,245 |
| 33 |
A structural variation reference for medical and population genetics
Ryan L. Collins et al. · Nature
Open access208 authors |
27 May 2020 |
1,205 |
| 34 |
Common Chronic Pain Conditions in Developed and Developing Countries: Gender and Age Differences and Comorbidity With Depression-Anxiety Disorders
Adley Tsang, Michael Von Korff, Sing Lee et al. · Journal of Pain
Open access |
8 Jul 2008 |
1,168 |
| 35 |
Prevalence of diabetes mellitus and impaired glucose regulation in Spain: the Di@bet.es Study
Federico Soriguer et al. · Diabetologia
Open access |
10 Oct 2011 |
1,160 |
| 36 |
A 14-Item Mediterranean Diet Assessment Tool and Obesity Indexes among High-Risk Subjects: The PREDIMED Trial
Miguel Ángel Martínez‐González et al. · PLoS ONE
Open access |
14 Aug 2012 |
1,160 |
| 37 |
Undertreatment of people with major depressive disorder in 21 countries
Graham Thornicroft et al. · The British Journal of Psychiatry
Open access |
Dec 2016 |
1,157 |
| 38 |
Stromal gene expression defines poor-prognosis subtypes in colorectal cancer
Alexandre Calon, Enza Lonardo, Antonio Berenguer et al. · Nature Genetics
|
23 Feb 2015 |
1,113 |
| 39 |
Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci
The Profile Study et al. · Nature Genetics
Open access192 authors |
8 Jun 2018 |
1,025 |
| 40 |
Heat-related mortality in Europe during the summer of 2022
Joan Ballester, Marcos Quijal-Zamorano, Raúl Fernando Méndez Turrubiates et al. · Nature Medicine
Open access |
Jul 2023 |
1,021 |
| 41 |
Allergic rhinitis
Jean Bousquet, Josep Maria Anto, Claus Bachert et al. · Nature Reviews Disease Primers
ReviewOpen access |
3 Dec 2020 |
950 |
| 42 |
Green spaces and cognitive development in primary schoolchildren
Payam Dadvand, Mark J Nieuwenhuijsen, Mikel Esnaola et al. · Proceedings of the National Academy of Sciences
Open access |
15 Jun 2015 |
944 |
| 43 |
Nonpharmacological Therapies in Alzheimer’s Disease: A Systematic Review of Efficacy
Javier Olazarán et al. · Dementia and Geriatric Cognitive Disorders
Review |
2010 |
940 |
| 44 |
DNA Methylation in Newborns and Maternal Smoking in Pregnancy: Genome-wide Consortium Meta-analysis
Bonnie R. Joubert et al. · The American Journal of Human Genetics
Open access106 authors |
Apr 2016 |
939 |
| 45 |
Mediterranean Diet and Age-Related Cognitive Decline
Cinta Valls‐Pedret, Aleix Sala‐Vila, Mercè Serra‐Mir et al. · JAMA Internal Medicine
Open access |
11 May 2015 |
935 |
| 46 |
Short Physical Performance Battery and all-cause mortality: systematic review and meta-analysis
Rita Pavasini et al. · BMC Medicine
ReviewOpen access |
Dec 2016 |
921 |
| 47 |
A validation study of the hospital anxiety and depression scale (HADS) in a Spanish population
M. Jesús Herrero, Jordi Blanch, Josep M. Peri et al. · General Hospital Psychiatry
|
Jul 2003 |
919 |
| 48 |
Development of the EQ-5D-Y: a child-friendly version of the EQ-5D
Nora Wille, Xavier Costa Badia, Gouke J. Bonsel et al. · Quality of Life Research
Open access |
19 Apr 2010 |
912 |
| 49 |
Benchmarking Complications Associated with Esophagectomy
Donald E. Low et al. · Annals of Surgery
Open access |
5 Dec 2017 |
903 |
| 50 |
Don’t fear ‘fear conditioning’: Methodological considerations for the design and analysis of studies on human fear acquisition, extinction, and return of fear
Tina B. Lonsdorf et al. · Neuroscience & Biobehavioral Reviews
Open access |
3 Mar 2017 |
893 |