| 1 |
Association analysis identifies 65 new breast cancer risk loci
Kyriaki Michailidou et al. · Nature
Open access362 authors |
20 Oct 2017 |
1,602 |
| 2 |
Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes
Nasim Mavaddat et al. · The American Journal of Human Genetics
Open access269 authors |
13 Dec 2018 |
1,213 |
| 3 |
Large-scale genotyping identifies 41 new loci associated with breast cancer risk
Kyriaki Michailidou et al. · Nature Genetics
Open access222 authors |
27 Mar 2013 |
1,109 |
| 4 |
MicroRNA Related Polymorphisms and Breast Cancer Risk
Sofia Khan et al. · PLoS ONE
Open access164 authors |
12 Nov 2014 |
638 |
| 5 |
Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer
BOCS et al. · Nature Genetics
Open access248 authors |
9 Mar 2015 |
638 |
| 6 |
Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer
Australian Cancer Study et al. · Nature Genetics
Open access443 authors |
27 Mar 2013 |
544 |
| 7 |
Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer
ABCTB Investigators et al. · Nature Genetics
Open access476 authors |
23 Oct 2017 |
477 |
| 8 |
Genome-wide association studies identify four ER negative–specific breast cancer risk loci
The Gene ENvironmental Interaction and breast CAncer (GENICA) Network et al. · Nature Genetics
Open access274 authors |
27 Mar 2013 |
422 |
| 9 |
Heterogeneity of Breast Cancer Associations with Five Susceptibility Loci by Clinical and Pathological Characteristics
Montserrat García‐Closas et al. · PLoS Genetics
Open access113 authors |
25 Apr 2008 |
394 |
| 10 |
Adherence of Human Vaginal Lactobacilli to Vaginal Epithelial Cells and Interaction with Uropathogens
Soledad Boris, Juan E. Suárez, Fernando Vázquez et al. · Infection and Immunity
Open access |
May 1998 |
363 |
| 11 |
Genetically Predicted Body Mass Index and Breast Cancer Risk: Mendelian Randomization Analyses of Data from 145,000 Women of European Descent
Yan Ping Guo et al. · PLoS Medicine
Open access111 authors |
23 Aug 2016 |
293 |
| 12 |
Tumor MicroRNA Expression Profiling Identifies Circulating MicroRNAs for Early Breast Cancer Detection
Nerea Matamala, María Teresa Vargas, Ricardo González‐Cámpora et al. · Clinical Chemistry
|
9 Jun 2015 |
224 |
| 13 |
PALB2, CHEK2 and ATM rare variants and cancer risk: data from COGS
Melissa C. Southey et al. · Journal of Medical Genetics
Open access328 authors |
5 Sep 2016 |
221 |
| 14 |
Functional Variants at the 11q13 Risk Locus for Breast Cancer Regulate Cyclin D1 Expression through Long-Range Enhancers
Juliet D. French et al. · The American Journal of Human Genetics
Open access211 authors |
27 Mar 2013 |
216 |
| 15 |
Low penetrance breast cancer susceptibility loci are associated with specific breast tumor subtypes: findings from the Breast Cancer Association Consortium
Annegien Broeks et al. · Human Molecular Genetics
Open access155 authors |
19 May 2011 |
173 |
| 16 |
Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170
EMBRACE et al. · Nature Genetics
Open access252 authors |
29 Feb 2016 |
172 |
| 17 |
Differential inflammatory responses in aging and disease: TNF-α and IL-6 as possible biomarkers
David de Gonzalo‐Calvo, Kim Neitzert, María Fernández Fernández et al. · Free Radical Biology and Medicine
Open access |
2 Jun 2010 |
167 |
| 18 |
The MICA-A9 triplet repeat polymorphism in the transmembrane region confers additional susceptibility to the development of psoriatic arthritis and is independent of the association of Cw*0602 in psoriasis
Segundo R. Gonzalez, Jesús Martı́nez-Borra, Juan Carlos Torre‐Alonso et al. · Arthritis & Rheumatism
|
May 1999 |
147 |
| 19 |
A polyarticular onset predicts erosive and deforming disease in psoriatic arthritis
Rubén Queiró, J C Torre-Alonso, T Tinturé-Eguren et al. · Annals of the Rheumatic Diseases
Open access |
13 Dec 2002 |
140 |
| 20 |
CCR5 (chemokine receptor-5) DNA-polymorphism influences the severity of rheumatoid arthritis
I. Zapico, Eliécer Coto, A Rodríguez et al. · Genes and Immunity
|
Apr 2000 |
133 |
| 21 |
Interleukin 6, soluble tumor necrosis factor receptor I and red blood cell distribution width as biological markers of functional dependence in an elderly population: A translational approach
David de Gonzalo‐Calvo, Beatriz de Luxán‐Delgado, Susana Rodríguez‐González et al. · Cytokine
Open access |
5 Feb 2012 |
129 |
| 22 |
Refined histopathological predictors of BRCA1 and BRCA2mutation status: a large-scale analysis of breast cancer characteristics from the BCAC, CIMBA, and ENIGMA consortia
Amanda B. Spurdle et al. · Breast Cancer Research
Open access197 authors |
22 Dec 2014 |
126 |
| 23 |
Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation
Maya Ghoussaini et al. · Nature Communications
Open access216 authors |
23 Sep 2014 |
123 |
| 24 |
Characterization of indigenous vaginal lactobacilli from healthy women as probiotic candidates.
Rebeca Martín, Nora E. Soberón, Mario Vaneechoutte et al. · PubMed
Open access |
Dec 2008 |
119 |
| 25 |
Fine-Scale Mapping of the FGFR2 Breast Cancer Risk Locus: Putative Functional Variants Differentially Bind FOXA1 and E2F1
Kerstin B. Meyer et al. · The American Journal of Human Genetics
Open access200 authors |
27 Nov 2013 |
117 |
| 26 |
Prevalence of Kaposi's sarcoma‐associated herpesvirus infection in sex workers and women from the general population in Spain
Sílvia de Sanjosé, Vickie Ann Marshall, Judit Solà et al. · International Journal of Cancer
Open access |
18 Dec 2001 |
111 |
| 27 |
Risk variants for psoriasis vulgaris in a large case–control collection and association with clinical subphenotypes
Antonio Julià et al. · Human Molecular Genetics
Open access |
19 Jul 2012 |
109 |
| 28 |
Assessing interactions between the associations of common genetic susceptibility variants, reproductive history and body mass index with breast cancer risk in the breast cancer association consortium: a combined case-control study
Roger Laughlin Milne et al. · Breast Cancer Research
Open access |
31 Dec 2010 |
97 |
| 29 |
Concordance of Prevalence of Human Papillomavirus DNA in Anogenital and Oral Infections in a High-Risk Population
M. Paz Cañadas, Francesc Xavier Bosch, María Luisa Junquera et al. · Journal of Clinical Microbiology
Open access |
Mar 2004 |
96 |
| 30 |
Psoriatic spondyloarthropathy: A comparative study between HLA-B27 positive and HLA-B27 negative disease
Rubén Queiró, Cristina Sarasqueta, Joaquín María Belzunegui et al. · Seminars in Arthritis and Rheumatism
|
Jun 2002 |
94 |
| 31 |
Relationship between functional ability in older people, immune system status, and intensity of response to CMV
Marco Antonio Moro‐García, Rebeca Alonso‐Arias, Antonio López‐Vázquez et al. · AGE
Open access |
12 Apr 2011 |
94 |
| 32 |
Fine-Scale Mapping of the 5q11.2 Breast Cancer Locus Reveals at Least Three Independent Risk Variants Regulating MAP3K1
Dylan M. Glubb et al. · The American Journal of Human Genetics
Open access215 authors |
19 Dec 2014 |
90 |
| 33 |
WHO Ordinal Scale and Inflammation Risk Categories in COVID-19. Comparative Study of the Severity Scales
Manuel Rubio‐Rivas et al. · Journal of General Internal Medicine
Open access |
8 Apr 2022 |
89 |
| 34 |
Clinically Asymptomatic Axial Disease in Psoriatic Spondyloarthropathy. A Retrospective Study
Rubén Queiró, Joaquín María Belzunegui, C. Gonza ́lez et al. · Clinical Rheumatology
|
Feb 2002 |
85 |
| 35 |
Clinical features and predictive factors in psoriatic arthritis–related uveitis
Rubén Queiró, Juan Carlos Gómez de la Torre, Joaquín María Belzunegui et al. · Seminars in Arthritis and Rheumatism
|
Feb 2002 |
84 |
| 36 |
The role of genetic breast cancer susceptibility variants as prognostic factors
Peter Andreas Fasching et al. · Human Molecular Genetics
Open access |
24 Apr 2012 |
84 |
| 37 |
Associations of common variants at 1p11.2 and 14q24.1 (RAD51L1) with breast cancer risk and heterogeneity by tumor subtype: findings from the Breast Cancer Association Consortium†
Jonine D. Figueroa et al. · Human Molecular Genetics
Open access147 authors |
18 Aug 2011 |
80 |
| 38 |
Genetic variation at the glycosaminoglycan metabolism pathway contributes to the risk of psoriatic arthritis but not psoriasis
Adrià Aterido et al. · Annals of the Rheumatic Diseases
|
14 Dec 2018 |
78 |
| 39 |
NKG2D expression in CD4+ T lymphocytes as a marker of senescence in the aged immune system
Rebeca Alonso‐Arias, Marco Antonio Moro‐García, Antonio López‐Vázquez et al. · AGE
Open access |
5 Jan 2011 |
78 |
| 40 |
Contribution of KIR3DL1/3DS1 to ankylosing spondylitis in human leukocyte antigen-B27 Caucasian populations
Carlos López‐Larrea, Miguel Ángel Blanco-Gelaz, Juan Carlos Torre‐Alonso et al. · Arthritis Research & Therapy
Open access |
28 Jun 2006 |
77 |
| 41 |
Synergistic Effect between Apolipoprotein E and Angiotensinogen Gene Polymorphisms in the Risk for Early Myocardial Infarction
Alberto Batalla, Ruth Álvarez, Julián R. Reguero et al. · Clinical Chemistry
|
Dec 2000 |
74 |
| 42 |
Surgical inflammation: a pathophysiological rainbow
José Ignacio Arias, Jose-Ignacio Arias, Maria-Angeles Aller et al. · Journal of Translational Medicine
Open access |
23 Mar 2009 |
73 |
| 43 |
Genome-wide association study of germline variants and breast cancer-specific mortality
NBCS Collaborators et al. · British Journal of Cancer
Open access237 authors |
21 Feb 2019 |
72 |
| 44 |
Body mass index and breast cancer survival: a Mendelian randomization analysis
Qi Jin Guo et al. · International Journal of Epidemiology
Open access135 authors |
29 Jun 2017 |
71 |
| 45 |
Intensity of the Humoral Response to Cytomegalovirus Is Associated with the Phenotypic and Functional Status of the Immune System
Rebeca Alonso‐Arias, Marco Antonio Moro‐García, Ainara Echeverría et al. · Journal of Virology
Open access |
6 Feb 2013 |
71 |
| 46 |
Five Polymorphisms and Breast Cancer Risk: Results from the Breast Cancer Association Consortium
Mia M. Gaudet et al. · Cancer Epidemiology Biomarkers & Prevention
Open access116 authors |
May 2009 |
68 |
| 47 |
Predicting Clinical Outcome with Phenotypic Clusters in COVID-19 Pneumonia: An Analysis of 12,066 Hospitalized Patients from the Spanish Registry SEMI-COVID-19
Manuel Rubio‐Rivas et al. · Journal of Clinical Medicine
Open access |
29 Oct 2020 |
67 |
| 48 |
Overweight in elderly people induces impaired autophagy in skeletal muscle
Yaiza Potes, Beatriz de Luxán‐Delgado, Susana Rodríguez‐González et al. · Free Radical Biology and Medicine
Open access |
23 May 2017 |
67 |
| 49 |
Relationship between Mutations in the gyrA Gene and Quinolone Resistance in Clinical Isolates of Corynebacterium striatum and Corynebacterium amycolatum
Josep Maria Sierra, Luis Martı́nez-Martı́nez, Fernando Vázquez et al. · Antimicrobial Agents and Chemotherapy
Open access |
26 Apr 2005 |
67 |
| 50 |
Genetic analysis of the vitamin D receptor gene in two epithelial cancers: melanoma and breast cancer case-control studies
Eva Ayala Barroso, Lara Paula Fernández, Roger Laughlin Milne et al. · BMC Cancer
Open access |
Dec 2008 |
66 |