| 1 |
Driving Pressure and Survival in the Acute Respiratory Distress Syndrome
Marcelo B. P. Amato, Maureen O. Meade, Arthur S. Slutsky et al. · New England Journal of Medicine
Open access |
18 Feb 2015 |
2,879 |
| 2 |
Association Between Administration of Systemic Corticosteroids and Mortality Among Critically Ill Patients With COVID-19
The WHO Rapid Evidence Appraisal for COVID-19 Therapies (REACT) Working Group et al. · JAMA
Open access |
2 Sep 2020 |
2,369 |
| 3 |
ESMO Consensus Guidelines for management of patients with colon and rectal cancer. A personalized approach to clinical decision making
Hans‐Joachim Schmoll et al. · Annals of Oncology
Open access |
25 Sep 2012 |
1,545 |
| 4 |
Recommendations for laparoscopic liver resection: a report from the second international consensus conference held in Morioka.
Go Wakabayashi et al. · PubMed
|
Apr 2015 |
1,344 |
| 5 |
Effect of Dexamethasone on Days Alive and Ventilator-Free in Patients With Moderate or Severe Acute Respiratory Distress Syndrome and COVID-19
Bruno Martins Tomazini et al. · JAMA
Open access |
2 Sep 2020 |
1,309 |
| 6 |
The Challenges of Tumor Mutational Burden as an Immunotherapy Biomarker
Denis L. Fontes Jardim, Aaron Michael Goodman, Débora De Melo Gagliato et al. · Cancer Cell
Open access |
30 Oct 2020 |
1,261 |
| 7 |
World Allergy Organization Anaphylaxis Guidance 2020
Victória Cardona, Ignacio Javier Ansotegui, Motohiro Ebisawa et al. · World Allergy Organization Journal
Open access |
Oct 2020 |
1,172 |
| 8 |
ERS statement on respiratory muscle testing at rest and during exercise
Pierantonio Laveneziana et al. · European Respiratory Journal
Open access |
7 Apr 2019 |
836 |
| 9 |
Eribulin versus dacarbazine in previously treated patients with advanced liposarcoma or leiomyosarcoma: a randomised, open-label, multicentre, phase 3 trial
Patrick Schöffski, Sant P. Chawla, Robert G. Maki et al. · The Lancet
Open access |
12 Feb 2016 |
782 |
| 10 |
Incidence, Predictors, and Outcomes of Aortic Regurgitation After Transcatheter Aortic Valve Replacement
Ganesh Athappan, Eshan A. Patvardhan, Emin Murat Tuzcu et al. · Journal of the American College of Cardiology
Open access |
Apr 2013 |
782 |
| 11 |
Association between driving pressure and development of postoperative pulmonary complications in patients undergoing mechanical ventilation for general anaesthesia: a meta-analysis of individual patient data
Ary Serpa Neto et al. · The Lancet Respiratory Medicine
Review |
5 Mar 2016 |
635 |
| 12 |
2015 update of the evidence base: World Allergy Organization anaphylaxis guidelines
F. Estelle R. Simons, Motohiro Ebisawa, Mario Sánchez‐Borges et al. · World Allergy Organization Journal
Open access |
2015 |
595 |
| 13 |
International Consensus Criteria for Pediatric Sepsis and Septic Shock
Luregn Jan Schlapbach et al. · JAMA
Open access |
21 Jan 2024 |
563 |
| 14 |
IgE allergy diagnostics and other relevant tests in allergy, a World Allergy Organization position paper
Ignacio Javier Ansotegui et al. · World Allergy Organization Journal
Open access |
Feb 2020 |
558 |
| 15 |
36th International Symposium on Intensive Care and Emergency Medicine
R. M. Bateman et al. · Critical Care
Open access2,440 authors |
Apr 2016 |
531 |
| 16 |
Delays and Disruptions in Cancer Health Care Due to COVID-19 Pandemic: Systematic Review
Rachel Riera, Ângela Maria Bagattini, Rafael Leite Pacheco et al. · JCO Global Oncology
ReviewOpen access |
22 Feb 2021 |
513 |
| 17 |
Transfusion reactions: prevention, diagnosis, and treatment
Meghan Delaney, Silvano Wendel, Rachel S. Bercovitz et al. · The Lancet
|
12 Apr 2016 |
511 |
| 18 |
Treatment of Endometriosis-Associated Pain with Elagolix, an Oral GnRH Antagonist
Hugh Stott Taylor et al. · New England Journal of Medicine
Open access |
19 May 2017 |
505 |
| 19 |
Planning cancer control in Latin America and the Caribbean
Paul Edward Goss et al. · The Lancet Oncology
Open access |
Apr 2013 |
505 |
| 20 |
Therapeutic versus prophylactic anticoagulation for patients admitted to hospital with COVID-19 and elevated D-dimer concentration (ACTION): an open-label, multicentre, randomised, controlled trial
Renato D. Lópes et al. · The Lancet
Open access |
Jun 2021 |
500 |
| 21 |
Sickle cell disease: an international survey of results of HLA-identical sibling hematopoietic stem cell transplantation
Éliane Gluckman et al. · Blood
Open access |
13 Dec 2016 |
493 |
| 22 |
Efficacy and safety of canagliflozin in subjects with type 2 diabetes and chronic kidney disease
J.‐F. Yale, George L. Bakris, Bertrand Cariou et al. · Diabetes Obesity and Metabolism
Open access |
6 Mar 2013 |
490 |
| 23 |
Bisphosphonate‐associated osteonecrosis of mandibular and maxillary bone
Cesar Augusto Migliorati, Mark M. Schubert, Douglas E. Peterson et al. · Cancer
|
31 May 2005 |
490 |
| 24 |
International Study to Evaluate PCR Methods for Detection of Trypanosoma cruzi DNA in Blood Samples from Chagas Disease Patients
Alejandro Gabriel Schijman et al. · PLoS neglected tropical diseases
Open access |
11 Jan 2011 |
481 |
| 25 |
ENETS Consensus Guidelines Update for Neuroendocrine Neoplasms of the Jejunum and Ileum
Bruno Niederle, Ulrich Frank Pape, Frederico Perego Costa et al. · Neuroendocrinology
Open access |
2016 |
478 |
| 26 |
C-Reactive Protein/Albumin Ratio Predicts 90-Day Mortality of Septic Patients
Otavio Ranzani, Fernando Godinho Zampieri, Daniel Neves Forte et al. · PLoS ONE
Open access |
12 Mar 2013 |
475 |
| 27 |
Ventilatory Variables and Mechanical Power in Patients with Acute Respiratory Distress Syndrome
Eduardo Leite Vieira Costa, Arthur S. Slutsky, Laurent Brochard et al. · American Journal of Respiratory and Critical Care Medicine
Open access |
30 Mar 2021 |
466 |
| 28 |
ENETS Consensus Guidelines for the Management of Patients with Neuroendocrine Neoplasms from the Jejuno-Ileum and the Appendix Including Goblet Cell Carcinomas
Ulrich‐Frank Pape, Aurel A. Perren, Bruno Niederle et al. · Neuroendocrinology
Open access |
2012 |
466 |
| 29 |
Early Survival and Safety of ALPPS
Erik Schadde, Victoria Ardiles, R Robles et al. · Annals of Surgery
Open access |
7 Oct 2014 |
458 |
| 30 |
The epidemiology of sepsis in Brazilian intensive care units (the Sepsis PREvalence Assessment Database, SPREAD): an observational study
Flávia Ribeiro Machado et al. · The Lancet Infectious Diseases
Open access650 authors |
17 Aug 2017 |
426 |
| 31 |
A new American Joint Committee on Cancer staging system for cutaneous melanoma
Charles M. Balch, Antonio Carlos Buzaid, Michael B. Atkins et al. · Cancer
|
15 Mar 2000 |
425 |
| 32 |
Mitochondria as a Source of Reactive Oxygen and Nitrogen Species: From Molecular Mechanisms to Human Health
Tiago R. Figueira, Mario Henrique de Barros, Anamaria A. Camargo et al. · Antioxidants and Redox Signaling
|
17 Dec 2012 |
422 |
| 33 |
Effect of tocilizumab on clinical outcomes at 15 days in patients with severe or critical coronavirus disease 2019: randomised controlled trial
Viviane Cordeiro Veiga et al. · BMJ
Open access |
20 Jan 2021 |
407 |
| 34 |
An Evidence-based Staging System for Cutaneous Melanoma
Charles M. Balch, Seng-Jaw Soong, Michael B. Atkins et al. · CA A Cancer Journal for Clinicians
Open access |
May 2004 |
392 |
| 35 |
Macrophage: A Potential Target on Cartilage Regeneration
Tiago Lazzaretti Fernandes, Andreas H. Gomoll, Christian Lattermann et al. · Frontiers in Immunology
Open access |
10 Feb 2020 |
379 |
| 36 |
Azithromycin in addition to standard of care versus standard of care alone in the treatment of patients admitted to the hospital with severe COVID-19 in Brazil (COALITION II): a randomised clinical trial
Remo H.M. Furtado et al. · The Lancet
Open access |
5 Sep 2020 |
374 |
| 37 |
Systematic review of photobiomodulation for the management of oral mucositis in cancer patients and clinical practice guidelines
Yehuda Zadik, Praveen Ravindra Arany, Eduardo Rodrigues Fregnani et al. · Supportive Care in Cancer
ReviewOpen access |
8 Jul 2019 |
373 |
| 38 |
Frequency, signs and symptoms, and criteria adopted for long COVID‐19: A systematic review
Ana Luiza Cabrera Martimbianco, Rafael Leite Pacheco, Ângela Maria Bagattini et al. · International Journal of Clinical Practice
ReviewOpen access |
12 May 2021 |
370 |
| 39 |
An integrated multidisciplinary algorithm for the management of spinal metastases: an International Spine Oncology Consortium report
Daniel Eidelberg Spratt, Whitney H. Beeler, Fábio Ynoe de Moraes et al. · The Lancet Oncology
|
Dec 2017 |
366 |
| 40 |
Temozolomide for the Treatment of Brain Metastases Associated With Metastatic Melanoma: A Phase II Study
Sanjiv S. Agarwala, John M. Kirkwood, Martin Eric Gore et al. · Journal of Clinical Oncology
|
28 May 2004 |
360 |
| 41 |
Sepsis: evolving concepts and challenges
Reinaldo Salomão, Bianca Lima Ferreira, Matias Chiarastelli Salomão et al. · Brazilian Journal of Medical and Biological Research
Open access |
2019 |
349 |
| 42 |
Safety and Efficacy of Re-treating with Immunotherapy after Immune-Related Adverse Events in Patients with NSCLC
Fernando Costa Santini, Hira A. Rizvi, Andrew J. Plodkowski et al. · Cancer Immunology Research
Open access |
10 Jul 2018 |
332 |
| 43 |
Quiescent cancer cells resist T cell attack by forming an immunosuppressive niche
Pilar Baldominos et al. · Cell
Open access |
20 Apr 2022 |
330 |
| 44 |
Moral distress and its contribution to the development of burnout syndrome among critical care providers
Renata Rego Lins Fumis, Gustavo Adolpho Junqueira Amarante, Andréia de Fátima Nascimento et al. · Annals of Intensive Care
Open access |
2017 |
320 |
| 45 |
Intensity-modulated radiation therapy for head and neck cancer: Systematic review and meta-analysis
Gustavo Nader Marta, Valter Silva, Heloísa de Andrade Carvalho et al. · Radiotherapy and Oncology
Review |
13 Dec 2013 |
315 |
| 46 |
Brain aging in major depressive disorder: results from the ENIGMA major depressive disorder working group
Laura K. M. Han et al. · Molecular Psychiatry
Open access146 authors |
18 May 2020 |
314 |
| 47 |
Cortical thickness across the lifespan: Data from 17,075 healthy individuals aged 3–90 years
Sophia Frangou et al. · Human Brain Mapping
Open access205 authors |
17 Feb 2021 |
308 |
| 48 |
The surface topography of silicone breast implants mediates the foreign body response in mice, rabbits and humans
Joshua C. Doloff et al. · Nature Biomedical Engineering
|
21 Jun 2021 |
306 |
| 49 |
ENETS Consensus Guidelines for Neuroendocrine Neoplasms of the Appendix (Excluding Goblet Cell Carcinomas)
Ulrich‐Frank Pape, Bruno Niederle, Frederico Perego Costa et al. · Neuroendocrinology
Open access |
2016 |
299 |
| 50 |
Effect of Lowering V t on Mortality in Acute Respiratory Distress Syndrome Varies with Respiratory System Elastance
Ewan C. Goligher, Eduardo Leite Vieira Costa, Christopher J. Yarnell et al. · American Journal of Respiratory and Critical Care Medicine
|
13 Jan 2021 |
291 |