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Institution · Human Genome Sciences (United States)

Most cited papers from Human Genome Sciences (United States)

Human Genome Sciences (United States)

What are the most cited papers from Human Genome Sciences (United States)?

The most cited paper from Human Genome Sciences (United States) is "De novo transcript sequence reconstruction from RNA-seq using the Trinity platform for reference generation and analysis" (Brian J. Haas et al., 2013), with 9,312 citations. Next come "Genetic effects on gene expression across human tissues" (4,762) and "Global variation in copy number in the human genome" (4,397).

Showing 50 of 59 papers. Every paper with more than 542 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 De novo transcript sequence reconstruction from RNA-seq using the Trinity platform for reference generation and analysis Brian J. Haas et al. · Nature Protocols Open access 11 Jul 2013 9,312
2 Genetic effects on gene expression across human tissues François Aguet et al. · Nature Open access250 authors 10 Oct 2017 4,762
3 Global variation in copy number in the human genome Richard Redon et al. · Nature Open access Nov 2006 4,397
4 The complete genome sequence of the gastric pathogen Helicobacter pylori Jean-F. Tomb et al. · Nature Open access 7 Aug 1997 3,570
5 Comprehensive molecular characterization of urothelial bladder carcinoma John N. Weinstein et al. · Nature Open access294 authors 28 Jan 2014 3,110
6 FLICE, A Novel FADD-Homologous ICE/CED-3–like Protease, Is Recruited to the CD95 (Fas/APO-1) Death-Inducing Signaling Complex Marta Muzio, Arul M. Chinnaiyan, Frank Christian Kischkel et al. · Cell Open access Jun 1996 3,080
7 Efficacy and safety of belimumab in patients with active systemic lupus erythematosus: a randomised, placebo-controlled, phase 3 trial Sandra Navarra, Renato Guzmán, A Gallacher et al. · The Lancet Feb 2011 2,098
8 Targeted capture and massively parallel sequencing of 12 human exomes Sarah Boon Hsi Ng, Emily H. Turner, Peggy D. Robertson et al. · Nature Open access 16 Aug 2009 2,073
9 TIGR Gene Indices clustering tools (TGICL): a software system for fast clustering of large EST datasets Geo M. Pertea, Xiaoqiu Huang, Liang Feng et al. · Bioinformatics Open access 21 Mar 2003 2,031
10 [9] TM4 Microarray Software Suite Alexander I. Saeed, NIRMAL K. BHAGABATI, John C. Braisted et al. · Methods in enzymology on CD-ROM/Methods in enzymology Book chapter 2006 2,019
11 Mutation of a mutL Homolog in Hereditary Colon Cancer Nickolas Papadopoulos, Nicholas C. Nicolaides, Ying-Fei Wei et al. · Science 18 Mar 1994 1,853
12 Genesis: cluster analysis of microarray data Alexander Sturn, John Quackenbush, Zlatko Trajanoski · Bioinformatics Open access 2002 1,816
13 The Receptor for the Cytotoxic Ligand TRAIL Guohua Pan, Karen M. O’Rourke, Arul M. Chinnaiyan et al. · Science 4 Apr 1997 1,786
14 A phase III, randomized, placebo-controlled study of belimumab, a monoclonal antibody that inhibits B lymphocyte stimulator, in patients with systemic lupus erythematosus Richard Alan Furie, Michelle Petri, Omid Zamani et al. · Arthritis & Rheumatism Open access Sep 2011 1,693
15 Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs Yasushi Okazaki et al. · Nature Open access137 authors Dec 2002 1,657
16 LYVE-1, a New Homologue of the CD44 Glycoprotein, Is a Lymph-specific Receptor for Hyaluronan Suneale Banerji, Jian Ni, Shuxia Wang et al. · The Journal of Cell Biology Open access 22 Feb 1999 1,605
17 Mutations of two P/WS homologues in hereditary nonpolyposis colon cancer Nicholas C. Nicolaides, Nickolas Papadopoulos, Bo Liu et al. · Nature Sep 1994 1,552
18 An Antagonist Decoy Receptor and a Death Domain-Containing Receptor for TRAIL Guohua Pan, Jian Ni, Ying-Fei Wei et al. · Science 8 Aug 1997 1,507
19 Differentiation of Embryonic Stem Cells to Insulin-Secreting Structures Similar to Pancreatic Islets Nadya L. Lumelsky, Olivier Blondel, Pascal Laeng et al. · Science 18 May 2001 1,461
20 The genome of the model beetle and pest Tribolium castaneum Stephen J. Richards et al. · Nature Open access191 authors 23 Mar 2008 1,437
21 Anti-virulence strategies to combat bacteria-mediated disease David A. Rasko, Vanessa Sperandio · Nature Reviews Drug Discovery Review 18 Jan 2010 1,390
22 Inhibition of mTORC1 leads to MAPK pathway activation through a PI3K-dependent feedback loop in human cancer Arkaitz Carracedo, Li Ma, Julie Teruya‐Feldstein et al. · Journal of Clinical Investigation Open access Aug 2008 1,389
23 The TIGR Rice Genome Annotation Resource: improvements and new features Shuai Ouyang, W. Zhu, John P. Hamilton et al. · Nucleic Acids Research Open access 2 Dec 2006 1,366
24 PD-L1 Immunohistochemistry Assays for Lung Cancer: Results from Phase 1 of the Blueprint PD-L1 IHC Assay Comparison Project Fred R. Hirsch et al. · Journal of Thoracic Oncology Open access 29 Nov 2016 1,274
25 Direct detection of early-stage cancers using circulating tumor DNA Jillian A. Phallen et al. · Science Translational Medicine Open access 16 Aug 2017 1,185
26 IRAK (Pelle) Family Member IRAK-2 and MyD88 as Proximal Mediators of IL-1 Signaling Marta Muzio, Jian Ni, Ping Feng et al. · Science 28 Nov 1997 1,170
27 BLyS: Member of the Tumor Necrosis Factor Family and B Lymphocyte Stimulator Paul A. Moore et al. · Science 9 Jul 1999 1,158
28 Detection of ultra-rare mutations by next-generation sequencing Michael W. Schmitt, Scott R. Kennedy, Jesse J. Salk et al. · Proceedings of the National Academy of Sciences Open access Aug 2012 1,123
29 B7-H3: A costimulatory molecule for T cell activation and IFN-γ production Andrei I. Chapoval, Jian Ni, Julie S. Lau et al. · Nature Immunology Mar 2001 1,032
30 A Guild of 45 CRISPR-Associated (Cas) Protein Families and Multiple CRISPR/Cas Subtypes Exist in Prokaryotic Genomes Daniel H. Haft, JEREMY D. SELENGUT, Emmanuel F. Mongodin et al. · PLoS Computational Biology Open access 8 Nov 2005 1,009
31 A Mutation in the Vesicle-Trafficking Protein VAPB Causes Late-Onset Spinal Muscular Atrophy and Amyotrophic Lateral Sclerosis Agnes Lumi Nishimura, Miguel Mitne‐Neto, Helga Cristina Almeida da Silva et al. · The American Journal of Human Genetics Open access 4 Oct 2004 1,001
32 Evolution of Neoantigen Landscape during Immune Checkpoint Blockade in Non–Small Cell Lung Cancer Valsamo Anagnostou et al. · Cancer Discovery Open access 28 Dec 2016 921
33 Draft Genome Sequence of the Sexually Transmitted Pathogen Trichomonas vaginalis Jane M. Carlton et al. · Science Open access 12 Jan 2007 846
34 Origins of the E. coli Strain Causing an Outbreak of Hemolytic–Uremic Syndrome in Germany David A. Rasko et al. · New England Journal of Medicine Open access 27 Jul 2011 836
35 Elevated serum B lymphocyte stimulator levels in patients with systemic immune-based rheumatic diseases Gurtej S. Cheema, Viktor V. Roschke, David M. Hilbert et al. · Arthritis & Rheumatism 2001 807
36 High grade serous ovarian carcinomas originate in the fallopian tube Sana Intidhar Labidi‐Galy et al. · Nature Communications Open access 17 Oct 2017 791
37 LIGHT, a New Member of the TNF Superfamily, and Lymphotoxin α Are Ligands for Herpesvirus Entry Mediator Davide Mauri, Reinhard Ebner, Rebecca I. Montgomery et al. · Immunity Open access 1998 779
38 GAGE: A critical evaluation of genome assemblies and assembly algorithms Steven L. Salzberg, Adam M. Phillippy, Aleksey V. Zimin et al. · Genome Research Open access 6 Dec 2011 757
39 Cutting Edge: A Role for B Lymphocyte Stimulator in Systemic Lupus Erythematosus Jun Zhang, Viktor V. Roschke, Kevin P. Baker et al. · The Journal of Immunology Open access 2001 737
40 Nod1, an Apaf-1-like Activator of Caspase-9 and Nuclear Factor-κB Naohiro Inohara, Takeyoshi Koseki, Luis del Peso et al. · Journal of Biological Chemistry Open access May 1999 736
41 Cathepsin K, but Not Cathepsins B, L, or S, Is Abundantly Expressed in Human Osteoclasts Fred H. Drake, Robert A. Dodds, Ian E. James et al. · Journal of Biological Chemistry Open access May 1996 718
42 Molecular architecture and assembly of the DDB1–CUL4A ubiquitin ligase machinery Stéphane Angers, Ti Li, Xianhua Yi et al. · Nature 10 Sep 2006 682
43 Bacterial diversity in the oral cavity of 10 healthy individuals Elisabeth M. Bik, Clara Davis Long, Gary C. Armitage et al. · The ISME Journal Open access 25 Mar 2010 666
44 Signal Transduction by DR3, a Death Domain-Containing Receptor Related to TNFR-1 and CD95 Arul M. Chinnaiyan, Karen M. O’Rourke, Guo-Liang Yu et al. · Science 8 Nov 1996 657
45 LAMARC 2.0: maximum likelihood and Bayesian estimation of population parameters Mary K. Kuhner · Bioinformatics 12 Jan 2006 655
46 TL1A Is a TNF-like Ligand for DR3 and TR6/DcR3 and Functions as a T Cell Costimulator Thi-Sau Migone et al. · Immunity Open access Mar 2002 651
47 Exploration of Tumor-Suppressive MicroRNAs Silenced by DNA Hypermethylation in Oral Cancer Ken‐ichi Kozaki, Issei Imoto, Seiki Mogi et al. · Cancer Research Apr 2008 618
48 Recommendations for the validation of immunoassays used for detection of host antibodies against biotechnology products Gopi Shankar, Viswanath Devanarayan, Lakshmi S. Amaravadi et al. · Journal of Pharmaceutical and Biomedical Analysis 20 Sep 2008 609
49 Thanatophoric dysplasia (types I and II) caused by distinct mutations in fibroblast growth factor receptor 3 Patricia L. Tavormina, Rita Shiang, Leslie Michels Thompson et al. · Nature Genetics Mar 1995 608
50 A phase II, randomized, double‐blind, placebo‐controlled, dose‐ranging study of belimumab in patients with active systemic lupus erythematosus Daniel J. Wallace, William Stohl, Richard Alan Furie et al. · Arthritis Care & Research Open access 27 Aug 2009 600

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.