Most cited papers from Human Immunome Project

Human Immunome Project

What are the most cited papers from Human Immunome Project?

The most cited paper from Human Immunome Project is "Which Pneumococcal Serogroups Cause the Most Invasive Disease: Implications for Conjugate Vaccine Formulation and Use, Part I" (William P. Hausdorff, John Bryant, Peter R. Paradiso et al., 2000), with 872 citations. Next come "Transcription Profiling-Based Identification of Staphylococcus aureus Genes Regulated by the agr and/or sarA Loci" (647) and "Commonality despite exceptional diversity in the baseline human antibody repertoire" (638).

Published TypeFieldAccessCitations

Showing 50 of 61 papers. Every paper with more than 48 citations is listed.

Most cited papers, sortable by citations and release date
#	Paper
1	Which Pneumococcal Serogroups Cause the Most Invasive Disease: Implications for Conjugate Vaccine Formulation and Use, Part I William P. Hausdorff, John Bryant, Peter R. Paradiso et al. · Clinical Infectious Diseases	2000	872
2	Transcription Profiling-Based Identification of Staphylococcus aureus Genes Regulated by the agr and/or sarA Loci Paul M. Dunman, Ellen Murphy, Staci L. Haney et al. · Journal of Bacteriology	15 Dec 2001	647
3	Commonality despite exceptional diversity in the baseline human antibody repertoire Bryan S. Briney, Anne Inderbitzin, Collin Joyce et al. · Nature Open access	21 Jan 2019	638
4	Safety and Efficacy of High-Dose Intravenous Acyclovir in the Management of Neonatal Herpes Simplex Virus Infections David Winston Kimberlin et al. · PEDIATRICS	Aug 2001	576
5	Efficacy and safety of seven-valent conjugate pneumococcal vaccine in American Indian children: group randomised trial Katherine L. O'Flynn O'Brien, Lawrence H. Moulton, Raymond Reid et al. · The Lancet	Aug 2003	392
6	Enzyme-Linked Immunosorbent Assay for Quantitation of Human Antibodies to Pneumococcal Polysaccharides Catherine M. Wernette, Carl E. Frasch, Dace Viceps Madore et al. · Clinical and Vaccine Immunology Open access	Jul 2003	339
7	The Contribution of Specific Pneumococcal Serogroups to Different Disease Manifestations: Implications for Conjugate Vaccine Formulation and Use, Part II William P. Hausdorff, John Bryant, C. Kloek et al. · Clinical Infectious Diseases Open access	2000	334
8	Superior Relative Efficacy of Live Attenuated Influenza Vaccine Compared With Inactivated Influenza Vaccine in Young Children With Recurrent Respiratory Tract Infections Shai Ashkenazi, André Vertruyen, Javier Ar stegui et al. · The Pediatric Infectious Disease Journal	22 Sep 2006	317
9	Comparison of the Efficacy and Safety of Live Attenuated Cold-Adapted Influenza Vaccine, Trivalent, With Trivalent Inactivated Influenza Virus Vaccine in Children and Adolescents With Asthma Douglas Fleming, Pietro Crovari, Ulrich Wahn et al. · The Pediatric Infectious Disease Journal	22 Sep 2006	274
10	Comparison of Pneumococcal Conjugate Polysaccharide and Free Polysaccharide Vaccines in Elderly Adults: Conjugate Vaccine Elicits Improved Antibacterial Immune Responses and Immunological Memory Andres De Roux, Beate Schmöele-Thoma, George R. Siber et al. · Clinical Infectious Diseases	29 Feb 2008	267
11	Geographical differences in invasive pneumococcal disease rates and serotype frequency in young children William P. Hausdorff, George R. Siber, Peter R. Paradiso · The Lancet	Mar 2001	221
12	A Multiplexed Fluorescent Microsphere Immunoassay for Antibodies to Pneumococcal Capsular Polysaccharides Jerry W. Pickering, Thomas B. Martins, Ryan W. Greer et al. · American Journal of Clinical Pathology Open access	Apr 2002	179
13	Efficacy and Safety of a Live Attenuated, Cold-Adapted Influenza Vaccine, Trivalent Against Culture-Confirmed Influenza in Young Children in Asia John S. L. Tam, María Rosario Capeding, Lucy Chai See Lum et al. · The Pediatric Infectious Disease Journal	21 Jun 2007	178
14	Neurovirulence properties of recombinant vesicular stomatitis virus vectors in non-human primates J. Erik Johnson, Farooq Nasar, John W. Coleman et al. · Virology Open access	14 Nov 2006	160
15	Improving Vaccine-Induced Immunity: Can Baseline Predict Outcome? John S. Tsang, Carlota Dobaño, Pierre Van Damme et al. · Trends in Immunology ReviewOpen access	8 Apr 2020	154
16	Comparison of Physician and Computer Diagnostic Accuracy Hannah L. Semigran, David Michael Levine, Shantanu Nundy et al. · JAMA Internal Medicine Open access	10 Oct 2016	154
17	MarA-mediated overexpression of the AcrAB efflux pump results in decreased susceptibility to tigecycline in Escherichia coli David R. Keeney, Alexey V. Ruzin, Fionnuala McAleese et al. · Journal of Antimicrobial Chemotherapy	29 Oct 2007	154
18	HIV-1-specific antibody responses during acute and chronic HIV-1 infection Georgia D. Tomaras, Barton F. Haynes · Current Opinion in HIV and AIDS Open access	15 Aug 2009	154
19	Safety and Immunogenicity of a Purified F Protein Respiratory Syncytial Virus (PFP‐2) Vaccine in Seropositive Children with Bronchopulmonary Dysplasia Jessie R. Groothuis, S. J. King, Debbie A. Hogerman et al. · The Journal of Infectious Diseases	Feb 1998	133
20	A Randomized, Double-Blind Study of the Safety, Transmissibility and Phenotypic and Genotypic Stability of Cold-Adapted Influenza Virus Vaccine Timo Vesikari, Aino Karvonen, Tiina Korhonen et al. · The Pediatric Infectious Disease Journal	22 Jun 2006	129
21	Immune Activation Driven by CTLA-4 Blockade Augments Viral Replication at Mucosal Sites in Simian Immunodeficiency Virus Infection Valentina Cecchinato, Elżbieta Anna Tryniszewska, Zhong Min et al. · The Journal of Immunology Open access	Apr 2008	127
22	A rotational and axial motion system load frame insert for in situ high energy x-ray studies Paul A. Shade, Basil Blank, Jay C. Schuren et al. · Review of Scientific Instruments Open access	Sep 2015	122
23	Multinational study of pneumococcal serotypes causing acute otitis media in children William P. Hausdorff, Greg Yothers, Ron Dagan et al. · The Pediatric Infectious Disease Journal	Nov 2002	120
24	Efficacy and Safety of 1 and 2 Doses of Live Attenuated Influenza Vaccine in Vaccine-Naive Children Humberto Bracco Neto, Calil Kairala Farhat, Miguel Tregnaghi et al. · The Pediatric Infectious Disease Journal Open access	May 2009	118
25	Vaccine-associated enhanced disease: Case definition and guidelines for data collection, analysis, and presentation of immunization safety data Flor M. Muñoz, Jakob P. Cramer, Cornelia L. Dekker et al. · Vaccine Open access	23 Feb 2021	117
26	The Haemophilus influenzae Hap Autotransporter Binds to Fibronectin, Laminin, and Collagen IV Doran L. Fink, Bruce A. Green, Joseph W. St. Geme · Infection and Immunity Open access	Sep 2002	116
27	Biological age in healthy elderly predicts aging-related diseases including dementia Julia Wei Wu, Amber Yaqub, Ma Dai Yuan et al. · Scientific Reports Open access	5 Aug 2021	112
28	Application of genomics and proteomics for identification of bacterial gene products as potential vaccine candidates Deb N. Chakravarti, Michael J. Fiske, Leah D. Fletcher et al. · Vaccine	Nov 2000	108
29	Pneumococcal Conjugate Vaccine Serotypes ofStreptococcus pneumoniaeIsolates and the Antimicrobial Susceptibility of Such Isolates in Children with Otitis Media Moses Lutaakome Joloba, Anne Windau, Saralee Bajaksouzian et al. · Clinical Infectious Diseases	Nov 2001	104
30	Immunogenicity, safety and tolerability of heptavalent pneumococcal conjugate vaccine administered at 3, 5 and 11 months post-natally to pre- and full-term infants Susanna Esposito, Lorenza Pugni, Samantha Bosis et al. · Vaccine	8 Nov 2004	103
31	Recombinant PhpA Protein, a Unique Histidine Motif-Containing Protein fromStreptococcus pneumoniae, Protects Mice against Intranasal Pneumococcal Challenge Ying Zhang, Amy W. Masi, Vicki L. Barniak et al. · Infection and Immunity Open access	Jun 2001	100
32	A Pilot Study of the Effectiveness of a School-Based Influenza Vaccination Program James C. King, Ginny E. Cummings, Jeffrey J. Stoddard et al. · PEDIATRICS	Dec 2005	97
33	Comparative ability of plasmid IL-12 and IL-15 to enhance cellular and humoral immune responses elicited by a SIVgag plasmid DNA vaccine and alter disease progression following SHIV89.6P challenge in rhesus macaques Siew-Yen Chong, Michael A. Egan, Michele A. Kutzler et al. · Vaccine	15 Feb 2007	94
34	Development and deployment of COVID-19 vaccines for those most vulnerable Wayne Chester Koff, Theodore Schenkelberg, Tere M. Williams et al. · Science Translational Medicine	3 Feb 2021	89
35	Heterotypic protection from rotavirus infection in mice vaccinated with virus-like particles Baoming Jiang, Mary Kolb Estes, Christopher Barone et al. · Vaccine	Feb 1999	88
36	Synergistic Attenuation of Vesicular Stomatitis Virus by Combination of Specific G Gene Truncations and N Gene Translocations David K. Clarke, Farooq Nasar, Margaret S. Lee et al. · Journal of Virology Open access	7 Dec 2006	87
37	Invasive pneumococcal disease in children: geographic and temporal variations in incidence and serotype distribution Willam Hausdorff · European Journal of Pediatrics	Dec 2002	83
38	An Analytical Model Applied to a Multicenter Pneumococcal Enzyme-Linked Immunosorbent Assay Study Brian D. Plikaytis, David Goldblatt, Carl E. Frasch et al. · Journal of Clinical Microbiology Open access	Jun 2000	81
39	The Haemophilus influenzae Hap autotransporter mediates microcolony formation and adherence to epithelial cells and extracellular matrix via binding regions in the C-terminal end of the passenger domain Doran L. Fink, Amy Z. Buscher, Bruce Green et al. · Cellular Microbiology	Mar 2003	80
40	Development of an improved microneutralization assay for respiratory syncytial virus by automated plaque counting using imaging analysis Edyta Zielinska, Daiqing Liu, Hong-Yin Wu et al. · Virology Journal Open access	9 Nov 2005	77
41	Crystal Structure of the Oligomerization Domain of NSP4 from Rotavirus Reveals a Core Metal-binding Site Gregory D. Bowman, Ilana M. Nodelman, Orlie Levy et al. · Journal of Molecular Biology	Dec 2000	76
42	NadN and e (P4) Are Essential for Utilization of NAD and Nicotinamide Mononucleotide but Not Nicotinamide Riboside in Haemophilus influenzae Gabriele Kemmer, Thomas James Reilly, Joachim Schmidt-Brauns et al. · Journal of Bacteriology Open access	Jul 2001	75
43	Toxoids of Streptococcal Pyrogenic Exotoxin A Are Protective in Rabbit Models of Streptococcal Toxic Shock Syndrome Manuela Roggiani, Jennifer A. Stoehr, Stephen B. Olmsted et al. · Infection and Immunity Open access	Sep 2000	74
44	2001: a year of major advances in anthrax toxin research Michaël Mourez, Dana Borden Lacy, Kristina M. Cunningham et al. · Trends in Microbiology Review	Jun 2002	73
45	An efficient helper-virus-free method for rescue of recombinant paramyxoviruses and rhadoviruses from a cell line suitable for vaccine development Susan E. Witko, Cheryl S. Kotash, Rebecca M. Nowak et al. · Journal of Virological Methods	30 Mar 2006	72
46	Development of Streptococcal Pyrogenic Exotoxin C Vaccine Toxoids That Are Protective in the Rabbit Model of Toxic Shock Syndrome John K. McCormick, Timothy J. Tripp, Stephen B. Olmsted et al. · The Journal of Immunology Open access	Aug 2000	71
47	Assignment of Weight-Based Antibody Units for 13 Serotypes to a Human Antipneumococcal Standard Reference Serum, Lot 89-S(F) Sally A. Quataert, Kate Rittenhouse‐Olson, Carol S. Kirch et al. · Clinical and Vaccine Immunology Open access	Nov 2004	70
48	Vaccines for Moraxella catarrhalis John C. McMichael · Vaccine	Dec 2000	69
49	The Levels and Bactericidal Capacity of Antibodies Directed against the UspA1 and UspA2 Outer Membrane Proteins of Moraxella ( Branhamella ) catarrhalis in Adults and Children Dexiang Chen, Vicki L. Barniak, Karl R. VanDerMeid et al. · Infection and Immunity Open access	Mar 1999	69
50	Phase I Study of a Herpes Simplex Virus Type 2 (HSV-2) DNA Vaccine Administered to Healthy, HSV-2-Seronegative Adults by a Needle-Free Injection System Ashok Cattamanchi, Christine M. Posavad, Anna Wald et al. · Clinical and Vaccine Immunology Open access	11 Sep 2008	65

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.