Science Explorer Back to mapMap

Most cited papers from Human Longevity (United States)

What are the most cited papers from Human Longevity (United States)?

The most cited paper from Human Longevity (United States) is "The repertoire of mutational signatures in human cancer" (Ludmil B. Alexandrov et al., 2020), with 3,854 citations. Next come "Pan-cancer analysis of whole genomes" (3,360) and "Comparing Physician and Artificial Intelligence Chatbot Responses to Patient Questions Posted to a Public Social Media Forum" (2,604).

Showing 50 of 60 papers. Every paper with more than 208 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 The repertoire of mutational signatures in human cancer Ludmil B. Alexandrov et al. · Nature Open access1,384 authors 5 Feb 2020 3,854
2 Pan-cancer analysis of whole genomes Lauri A. Aaltonen et al. · Nature Open access1,324 authors 5 Feb 2020 3,360
3 Comparing Physician and Artificial Intelligence Chatbot Responses to Patient Questions Posted to a Public Social Media Forum John W. Ayers, Adam Poliak, Mark H. Dredze et al. · JAMA Internal Medicine Open access 28 Apr 2023 2,604
4 Concise Review: MSC-Derived Exosomes for Cell-Free Therapy Donald G. Phinney, Mark F. Pittenger · Stem Cells 10 Mar 2017 1,908
5 The Sequence of the Human Genome J. Craig Venter, Hamilton O. Smith, Mark D. Adams · Clinical Chemistry 17 Jul 2015 1,655
6 Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence Jeanne E. Savage et al. · Nature Genetics Open access117 authors 25 Jun 2018 1,445
7 The evolutionary history of 2,658 cancers Moritz Gerstung et al. · Nature Open access1,441 authors 5 Feb 2020 1,149
8 Gut Microbiome-Based Metagenomic Signature for Non-invasive Detection of Advanced Fibrosis in Human Nonalcoholic Fatty Liver Disease Rohit Seth Loomba et al. · Cell Metabolism Open access May 2017 1,139
9 Patterns of somatic structural variation in human cancer genomes Yilong Li et al. · Nature Open access1,411 authors 5 Feb 2020 1,005
10 Low Protein Intake Is Associated with a Major Reduction in IGF-1, Cancer, and Overall Mortality in the 65 and Younger but Not Older Population Morgan E. Levine, Jorge Suárez, Sebastian Brandhorst et al. · Cell Metabolism Open access Mar 2014 930
11 The trans-ancestral genomic architecture of glycemic traits Jihua Chen et al. · Nature Genetics Open access417 authors 31 May 2021 918
12 The BioMart community portal: an innovative alternative to large, centralized data repositories Damian Smedley et al. · Nucleic Acids Research Open access105 authors 20 Apr 2015 851
13 Interplay between the human gut microbiome and host metabolism Alessia Visconti, Caroline I. Le Roy, Fabio Rosa et al. · Nature Communications Open access 3 Oct 2019 801
14 Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing Isidro Cortés-Ciriano et al. · Nature Genetics Open access1,407 authors 5 Feb 2020 793
15 Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function Gail Davies et al. · Nature Communications Open access222 authors 22 May 2018 779
16 The fecal metabolome as a functional readout of the gut microbiome Jonas Zierer, Matthew A Jackson, Gabi Kastenmüller et al. · Nature Genetics Open access 24 May 2018 774
17 American Cancer Society nutrition and physical activity guideline for cancer survivors Cheryl L. Rock et al. · CA A Cancer Journal for Clinicians Open access 16 Mar 2022 749
18 Wildfire smoke impacts respiratory health more than fine particles from other sources: observational evidence from Southern California Rosana Aguilera, Thomas W. Corringham, Alexander Gershunov et al. · Nature Communications Open access 5 Mar 2021 712
19 Gut microbiome pattern reflects healthy ageing and predicts survival in humans Tomasz Maciej Wilmanski et al. · Nature Metabolism Open access 18 Feb 2021 710
20 Participation of people living with disabilities in physical activity: a global perspective Kathleen A. Martin Ginis, Hidde P. van der Ploeg, Charlie E Foster et al. · The Lancet Open access Jul 2021 558
21 Wastewater sequencing reveals early cryptic SARS-CoV-2 variant transmission Smruthi Karthikeyan et al. · Nature Open access118 authors 7 Jul 2022 533
22 Genetic diversity fuels gene discovery for tobacco and alcohol use Gretchen Saunders et al. · Nature Open access218 authors 7 Dec 2022 532
23 Climate Change and Mental Health: A Scoping Review Fiona Charlson, Suhailah Ali, Tarik Benmarhnia et al. · International Journal of Environmental Research and Public Health Open access 23 Apr 2021 507
24 Whole-genome sequencing identifies common-to-rare variants associated with human blood metabolites Tao Long et al. · Nature Genetics 6 Mar 2017 494
25 Status of Cardiovascular Health in US Adults and Children Using the American Heart Association’s New “Life’s Essential 8” Metrics: Prevalence Estimates From the National Health and Nutrition Examination Survey (NHANES), 2013 Through 2018 Donald M. Lloyd‐Jones, Hongyan Ning, Darwin R. Labarthe et al. · Circulation Open access 29 Jun 2022 486
26 Bi-ancestral depression GWAS in the Million Veteran Program and meta-analysis in >1.2 million individuals highlight new therapeutic directions Daniel F. Levey, Murray B. Stein, Frank R. Wendt et al. · Nature Neuroscience Open access 27 May 2021 442
27 Genomic basis for RNA alterations in cancer PCAWG Transcriptome Core Group et al. · Nature Open access1,461 authors 5 Feb 2020 425
28 Profound Perturbation of the Metabolome in Obesity Is Associated with Health Risk Elizabeth T. Cirulli, Lining Guo, Christine Leon Swisher et al. · Cell Metabolism Open access 11 Oct 2018 419
29 The landscape of viral associations in human cancers Marc Zapatka et al. · Nature Genetics Open access1,355 authors 5 Feb 2020 412
30 Fasting-Mimicking Diet Reduces HO-1 to Promote T Cell-Mediated Tumor Cytotoxicity Stefano Di Biase, Changhan David Lee, Sebastian Brandhorst et al. · Cancer Cell Open access Jul 2016 403
31 Assessing the contribution of rare variants to complex trait heritability from whole-genome sequence data Pierrick Wainschtein et al. · Nature Genetics Open access460 authors Mar 2022 370
32 Global environmental drivers of influenza Ethan R. Deyle, M. Cyrus Maher, Ryan D. Hernandez et al. · Proceedings of the National Academy of Sciences Open access 31 Oct 2016 369
33 Fasting-mimicking diet and hormone therapy induce breast cancer regression Irene Caffa et al. · Nature Open access 15 Jul 2020 367
34 Deep sequencing of 10,000 human genomes Amalio Telenti, Levi Pierce, William Biggs et al. · Proceedings of the National Academy of Sciences Open access 4 Oct 2016 363
35 Validation of biomarkers of aging Mahdi Moqri et al. · Nature Medicine Open access Feb 2024 344
36 The blood DNA virome in 8,000 humans Ahmed Moustafa, Chao Xie, Ewen F. Kirkness et al. · PLoS Pathogens Open access 22 Mar 2017 339
37 The Human Microbiome and Cancer Seesandra Venkatappa Rajagopala, Sanjay Vashee, Lauren M. Oldfield et al. · Cancer Prevention Research 18 Jan 2017 308
38 Intermittent and periodic fasting, longevity and disease Valter Daniel Longo, Maira Di Tano, Mark P. Mattson et al. · Nature Aging Open access 14 Jan 2021 290
39 Haplotype-phased genome and evolution of phytonutrient pathways of tetraploid blueberry Marivi Colle et al. · GigaScience Open access 31 Jan 2019 278
40 Human gene essentiality István Bartha, Julia di Iulio, J. Craig Venter et al. · Nature Reviews Genetics Review 30 Oct 2017 277
41 Non-invasive methods for imaging hepatic steatosis and their clinical importance in NAFLD Nobuharu Tamaki, Veeral H. Ajmera, Rohit Seth Loomba · Nature Reviews Endocrinology ReviewOpen access 23 Nov 2021 259
42 Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors Niamh Mullins et al. · Biological Psychiatry Open access1,123 authors 8 Sep 2021 256
43 Genome-wide association analyses of post-traumatic stress disorder and its symptom subdomains in the Million Veteran Program Murray B. Stein et al. · Nature Genetics Open access 28 Jan 2021 256
44 An ecosystem service perspective on urban nature, physical activity, and health Roy P. Remme et al. · Proceedings of the National Academy of Sciences Open access 14 May 2021 254
45 Meaningful associations in the adolescent brain cognitive development study Anthony Steven Dick et al. · NeuroImage Open access 17 Jun 2021 246
46 A deep learning system accurately classifies primary and metastatic cancers using passenger mutation patterns Wei Jiao et al. · Nature Communications Open access1,385 authors 5 Feb 2020 246
47 Prognostic value of day-of-injury plasma GFAP and UCH-L1 concentrations for predicting functional recovery after traumatic brain injury in patients from the US TRACK-TBI cohort: an observational cohort study Frederick Kofi Korley et al. · The Lancet Neurology Open access 10 Aug 2022 244
48 Integrative pathway enrichment analysis of multivariate omics data Marta Paczkowska et al. · Nature Communications Open access1,460 authors 5 Feb 2020 243
49 Supervised Injection Facilities as Harm Reduction: A Systematic Review Timothy W. Levengood, Grace Hyojung Yoon, Melissa J. Davoust et al. · American Journal of Preventive Medicine ReviewOpen access Jul 2021 237
50 City planning policies to support health and sustainability: an international comparison of policy indicators for 25 cities Melanie Lowe et al. · The Lancet Global Health Open access 10 May 2022 235

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.