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Most cited papers from Humanigen (United States)

What are the most cited papers from Humanigen (United States)?

The most cited paper from Humanigen (United States) is "GM-CSF inhibition reduces cytokine release syndrome and neuroinflammation but enhances CAR-T cell function in xenografts" (Rosalie M. Sterner et al., 2018), with 640 citations. Next come "α-Skeletal and α-Cardiac Actin Genes Are Coexpressed in Adult Human Skeletal Muscle and Heart" (234) and "GM-CSF Neutralization With Lenzilumab in Severe COVID-19 Pneumonia" (89).

Showing 32 of 32 papers. Every paper is listed.

Most cited papers, sortable by citations and release date
#Paper
1 GM-CSF inhibition reduces cytokine release syndrome and neuroinflammation but enhances CAR-T cell function in xenografts Rosalie M. Sterner et al. · Blood Open access 22 Nov 2018 640
2 α-Skeletal and α-Cardiac Actin Genes Are Coexpressed in Adult Human Skeletal Muscle and Heart Peter William Gunning, Phyllis A. Ponte, Helen M. Blau et al. · Molecular and Cellular Biology Open access Nov 1983 234
3 GM-CSF Neutralization With Lenzilumab in Severe COVID-19 Pneumonia Zelalem Temesgen et al. · Mayo Clinic Proceedings Open access 3 Sep 2020 89
4 Cardiac Actin Is the Major Actin Gene Product in Skeletal Muscle Cell Differentiation In Vitro William Bains, Phyllis A. Ponte, Helen M. Blau et al. · Molecular and Cellular Biology Aug 1984 74
5 Lenzilumab in hospitalised patients with COVID-19 pneumonia (LIVE-AIR): a phase 3, randomised, placebo-controlled trial Zelalem Temesgen et al. · The Lancet Respiratory Medicine Open access124 authors Dec 2021 74
6 Two-Level Regulation of Cardiac Actin Gene Transcription: Muscle-Specific Modulating Factors Can Accumulate before Gene Activation Adrian J. Minty, Helen M. Blau, Larry Kedes · Molecular and Cellular Biology Jun 1986 55
7 Phase 1 study of lenzilumab, a recombinant anti–human GM-CSF antibody, for chronic myelomonocytic leukemia Mrinal M. Patnaik, David Andrew Sallman, Abhishek Avinash Mangaonkar et al. · Blood Open access 15 Apr 2020 54
8 GM-CSF disruption in CART cells modulates T cell activation and enhances CART cell anti-tumor activity Michelle J. Cox et al. · Leukemia Open access 19 Apr 2022 42
9 Association of a Remote Patient Monitoring (RPM) Program With Reduced Hospitalizations in Cancer Patients With COVID-19 Joshua C. Pritchett, Bijan J. Borah, Aakash P. Desai et al. · JCO Oncology Practice Open access 4 Jun 2021 35
10 LENZILUMAB EFFICACY AND SAFETY IN NEWLY HOSPITALIZED COVID-19 SUBJECTS: RESULTS FROM THE LIVE-AIR PHASE 3 RANDOMIZED DOUBLE-BLIND PLACEBO-CONTROLLED TRIAL Zelalem Temesgen, Charles D. Burger, Jason V. Baker et al. · medRxiv PreprintOpen access 5 May 2021 34
11 Avian Embryonic Stem Cells Marie‐Cecile van de Lavoir, Christine Mather-Love · Methods in enzymology on CD-ROM/Methods in enzymology Book chapter 2006 29
12 First Clinical Use of Lenzilumab to Neutralize GM-CSF in Patients with Severe and Critical COVID-19 Pneumonia Zelalem Temesgen, Mariam Assi, Paschalis I. Vergidis et al. · medRxiv PreprintOpen access 12 Jun 2020 27
13 Antibody-mediated depletion of CCR10+EphA3+ cells ameliorates fibrosis in IPF Miriam Sayuri Hohmann et al. · JCI Insight Open access 4 May 2021 25
14 CAR-T–cell neurotoxicity: hope is on the horizon Omar Abdihamid · Blood Open access 16 May 2019 16
15 ZUMA-19: A Phase 1/2 Study of Axicabtagene Ciloleucel Plus Lenzilumab in Patients With Relapsed or Refractory Large B-Cell Lymphoma Olalekan O. Oluwole, Saad S. Kenderian, Parveen Shiraz et al. · Blood 15 Nov 2022 15
16 ZUMA-19: A Phase 1/2 Multicenter Study of Lenzilumab Use With Axicabtagene Ciloleucel (Axi-Cel) in Patients (Pts) With Relapsed or Refractory Large B Cell Lymphoma (R/R LBCL) Saad S. Kenderian, Olalekan O. Oluwole, Philip L. McCarthy et al. · Blood 4 Nov 2020 12
17 C reactive protein utilisation, a biomarker for early COVID-19 treatment, improves lenzilumab efficacy: results from the randomised phase 3 ‘LIVE-AIR’ trial Zelalem Temesgen, Colleen Frances Kelley, Frank Cerasoli et al. · Thorax Open access 6 Jul 2022 11
18 Clinical and economic benefits of lenzilumab plus standard of care compared with standard of care alone for the treatment of hospitalized patients with COVID-19 in the United States from the hospital perspective Adrian Kilcoyne, E. O. Jordan, Allen S. Zhou et al. · Journal of Medical Economics Open access 17 Jan 2022 7
19 GM-CSF Blockade during Chimeric Antigen Receptor T-Cell (CART) Therapy Reduces Cytokine Release Syndrome and Neurotoxicity and May Enhance CART Effector Functions Rosalie M. Sterner et al. · Transplantation and Cellular Therapy Open access 31 Jan 2019 6
20 Clinical and Economic Benefits of Lenzilumab Plus Standard of Care Compared with Standard of Care Alone for the Treatment of Hospitalized Patients with Coronavirus Disease 19 (COVID-19) from the Perspective of National Health Service England Adrian Kilcoyne, Edward Jordan, Kimberly Thomas et al. · ClinicoEconomics and Outcomes Research Open access Apr 2022 5
21 Phase I safety and bioimaging trial of KB004 (ifabotuzumab) in patients with glioblastoma Hui Kong Gan et al. · Journal of Nuclear Medicine May 2020 5
22 EARLY LENZILUMAB TREATMENT OF COVID-19 PATIENTS USING C-REACTIVE PROTEIN AS A BIOMARKER IMPROVES EFFICACY: RESULTS FROM THE PHASE 3 ‘LIVE-AIR’ TRIAL Zelalem Temesgen, Colleen Frances Kelley, Franklin Cerasoli et al. · medRxiv PreprintOpen access 2022 4
23 Improved Anti-Tumor Response of Chimeric Antigen Receptor T Cell (CART) Therapy after GM-CSF Inhibition Is Mechanistically Supported By a Novel Direct Interaction of GM-CSF with Activated Carts Michelle J. Cox, Charles J. Kuhlmann, Rosalie M. Sterner et al. · Transplantation and Cellular Therapy Open access 23 Jan 2020 3
24 COVID-19 associated chronic ARDS successfully treated with lenzilumab Juan D Pulido, Omar Ahmed, Rida Rasool et al. Preprint Oct 2020 2
25 P737: LENZILUMAB AND AZACITIDINE IMPROVE HEMATOLOGIC ALTERATIONS OF CHRONIC MYELOMONOCYTIC LEUKEMIA IN THE PREACH-M TRIAL David M. Ross, Devendra Hiwase, Steven Lane et al. · HemaSphere Open access Aug 2023 0
26 1134. Lenzilumab Treatment in COVID-19 Pneumonia Reduces Circulating Cytokines and Markers of Systemic Inflammation Dale Chappell, Adrian Kilcoyne, Frank Cerasoli et al. · Open Forum Infectious Diseases Open access Dec 2022 0
27 LENZILUMAB OUTCOMES ACCORDING TO RACE OF COVID-19 PARTICIPANTS IN THE LIVE-AIR PHASE 3 TRIAL Vincent C. Marconi, Adrian Kilcoyne, Franklin Cerasoli et al. · medRxiv PreprintOpen access 21 Aug 2022 0
28 ICLAS LAQ Network for the Promotion of Animal Quality in Research Patri Vergara, Gregory Ballard, Cynthia L Besch-Williford et al. · ILAR Journal Open access 2021 0
29 23: LENZILUMAB IN HOSPITALIZED BLACK/AFRICAN-AMERICAN COVID-19 PATIENTS: LIVE-AIR PHASE 3 STUDY RESULTS Zelalem Temesgen, Charles D. Burger, Claudia R. Libertin et al. · Critical Care Medicine 16 Dec 2021 0
30 S51 Evaluation of treatment approaches for hospitalized Covid-19 patients Adrian Kilcoyne, E. O. Jordan, Cameron Durrant et al. Conference paperOpen access Nov 2021 0
31 Clinical Benefits and Budget Impact of Lenzilumab plus Standard of Care Compared with Standard of Care Alone for the Treatment of Hospitalized Patients with COVID-19 in the United States from the Hospital Perspective Adrian Kilcoyne, E. O. Jordan, Allen S. Zhou et al. · medRxiv PreprintOpen access 10 Oct 2021 0
32 GM-CSF disruption in cart cells ameliorates cart cell activation and reduces activation-induced cell death Michelle J. Cox, Claudia Manriquez Roman, Reona Leo Sakemura et al. · Cytotherapy May 2021 0

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.