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Targeting senescence induced by age or chemotherapy with a polyphenol-rich natural extract improves longevity and healthspan in mice
Sara Zumerle et al. · Nature Aging
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CXCR1/2 Inhibition Blocks and Reverses Type 1 Diabetes in Mice
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CXCR1 and CXCR2 Inhibition by Ladarixin Improves Neutrophil-Dependent Airway Inflammation in Mice
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Cysteine Prevents the Reduction in Keratin Synthesis Induced by Iron Deficiency in Human Keratinocytes
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Enhanced NAMPT-Mediated NAD Salvage Pathway Contributes to Psoriasis Pathogenesis by Amplifying Epithelial Auto-Inflammatory Circuits
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Bioequivalence study of a new sildenafil 100 mg orodispersible film compared to the conventional film-coated 100 mg tablet administered to healthy male volunteers
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Development and Characterization of an Orodispersible Film for Vitamin D3 Supplementation
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Combination Drug Therapy for the Management of Chronic Neuropathic Pain
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16 Dec 2023 |
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Enzyme-Lignin Nanocapsules Are Sustainable Catalysts and Vehicles for the Preparation of Unique Polyvalent Bioinks
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CXCL1-CXCR1/2 signaling is induced in human temporal lobe epilepsy and contributes to seizures in a murine model of acquired epilepsy
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A new synthetic dual agonist of GPR120/GPR40 induces GLP-1 secretion and improves glucose homeostasis in mice
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Novel NSAID-Derived Drugs for the Potential Treatment of Alzheimer’s Disease
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DF2755A, a novel non-competitive allosteric inhibitor of CXCR1/2, reduces inflammatory and post-operative pain
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Speeding Up the Cocrystallization Process: Machine Learning-Combined Methods for the Prediction of Multicomponent Systems
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19 Oct 2023 |
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Orodispersible Film (ODF) Platform Based on Maltodextrin for Therapeutical Applications
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22 Sep 2022 |
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Circulating miR-200c is up-regulated in paediatric patients with familial hypercholesterolaemia and correlates with miR-33a/b levels: implication of a ZEB1-dependent mechanism
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N−N Bond Formation Using an Iodonitrene as an Umpolung of Ammonia: Straightforward and Chemoselective Synthesis of Hydrazinium Salts
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6 Oct 2020 |
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BCAAs and Di-Alanine supplementation in the prevention of skeletal muscle atrophy: preclinical evaluation in a murine model of hind limb unloading
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2 Aug 2021 |
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miR‐200a Modulates the Expression of the DNA Repair Protein OGG1 Playing a Role in Aging of Primary Human Keratinocytes
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Intradermal Injection of Hybrid Complexes of High- and Low-Molecular-Weight Hyaluronan: Where Do We Stand and Where Are We Headed in Regenerative Medicine?
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12 Mar 2024 |
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Inhibition of neutrophil O2− production by unsymmetrical methylene derivatives of benzopyrans: their use as potential antiinflammatory agents
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The ethical foundations of patient-centered care in aesthetic medicine
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5 Feb 2024 |
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Branched-Chain Amino Acids and Di-Alanine Supplementation in Aged Mice: A Translational Study on Sarcopenia
Paola Mantuano, Brigida Boccanegra, Gianluca Bianchini et al. · Nutrients
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9 Jan 2023 |
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Comparative Bioavailability Study of a New Vitamin D3 Orodispersible Film Versus a Marketed Oral Solution in Healthy Volunteers
Milko Massimiliano Radicioni, Carol Caverzasio, Stefano Rovati et al. · Clinical Drug Investigation
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16 Jan 2022 |
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Efficacy and Tolerability of Hybrid Complexes of High- and Low-Molecular-Weight Hyaluronan Intradermal Injections for the Treatment of Skin Roughness and Laxity of the Neck
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17 Sep 2022 |
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Evaluation of Wound Healing Activity of Salvia haenkei Hydroalcoholic Aerial Part Extract on in vitro and in vivo Experimental Models
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Ergogenic Effect of BCAAs and L-Alanine Supplementation: Proof-of-Concept Study in a Murine Model of Physiological Exercise
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30 Jul 2020 |
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Novel 1,4-Dihydropyridines as Specific Binders and Activators of SIRT3 Impair Cell Viability and Clonogenicity and Downregulate Hypoxia-Induced Targets in Cancer Cells
Clemens Zwergel et al. · Journal of Medicinal Chemistry
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13 Jul 2023 |
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Hyaluronan Hydrogels for Injection in Superficial Dermal Layers: An In Vitro Characterization to Compare Performance and Unravel the Scientific Basis of Their Indication
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2 Jun 2021 |
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Rifaximin, a Rifamycin Derivative for Use in the Treatment of Intestinal Bacterial Infections in Seriously Disabled Patients
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Restoring Adipose Tissue Homeostasis in Response to Aging: Initial Clinical Experience with Profhilo Structura®
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28 Jul 2023 |
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Evaluation of the efficacy of a new hyaluronic acid gel on dynamic and static wrinkles in volunteers with moderate aging/photoaging
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In vitro assessment of nutraceutical compounds and novel nutraceutical formulations in a liver-steatosis-based model
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Double Michael addition/aza-cyclization: a valuable sequence for the construction of symmetrical and unsymmetrical spirobarbiturate-pyridines
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Efficacy and tolerability of Profhilo® Structura intended to restore lateral cheek fat compartment: An observational pilot study
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24 Feb 2023 |
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31 Oct 2022 |
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miR-200c inhibition and catalase accelerate diabetic wound healing
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13 Feb 2025 |
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Ketoprofen, lysine and gabapentin co-crystal magnifies synergistic efficacy and tolerability of the constituent drugs: Pre-clinical evidences towards an innovative therapeutic approach for neuroinflammatory pain
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8 May 2023 |
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Elucidations on the Performance and Reversibility of Treatment with Hyaluronic Acid Based Dermal Fillers: In vivo and in vitro Approaches
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Dec 2022 |
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Doxorubicin induces an alarmin-like TLR4-dependent autocrine/paracrine action of Nucleophosmin in human cardiac mesenchymal progenitor cells
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Branched‐Chain Amino Acids and Di‐Alanine Supplementation Attenuates Muscle Atrophy in a Murine Model of Cancer Cachexia
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31 May 2025 |
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Orodispersible Film Based on Maltodextrin: A Convenient and Suitable Method for Iron Supplementation
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23 May 2023 |
12 |