Most cited papers from Ichimaru Pharcos (Japan)

Ichimaru Pharcos (Japan)

What are the most cited papers from Ichimaru Pharcos (Japan)?

The most cited paper from Ichimaru Pharcos (Japan) is "Interaction of Phytoestrogens with Estrogen Receptors .ALPHA. and .BETA.(II)." (Keiko Morito, Tohru Aomori, Toshiharu Hirose et al., 2002), with 464 citations. Next come "Triterpene Acids from the Leaves ofPerilla frutescensand Their Anti-inflammatory and Antitumor-promoting Effects" (260) and "Anti-inflammatory activities of the triterpene acids from the resin of Boswellia carteri" (195).

Published FieldAccessCitations

Showing 50 of 61 papers. Every paper with more than 5 citations is listed.

Most cited papers, sortable by citations and release date
#	Paper
1	Interaction of Phytoestrogens with Estrogen Receptors .ALPHA. and .BETA.(II). Keiko Morito, Tohru Aomori, Toshiharu Hirose et al. · Biological and Pharmaceutical Bulletin Open access	2002	464
2	Triterpene Acids from the Leaves ofPerilla frutescensand Their Anti-inflammatory and Antitumor-promoting Effects Norihiro Banno, Toshihiro Akihisa, Harukuni Tokuda et al. · Bioscience Biotechnology and Biochemistry	2004	260
3	Anti-inflammatory activities of the triterpene acids from the resin of Boswellia carteri Norihiro Banno, Toshihiro Akihisa, Ken Yasukawa et al. · Journal of Ethnopharmacology	18 Mar 2006	195
4	Screening System for the Maillard Reaction Inhibitor from Natural Product Extracts. Nobuyasu Matsuura, Tadashi Aradate, Chihiro Sasaki et al. · Eisei kagaku Open access	2002	177
5	Novel Method for the Preparation of Controlled-Release Theophylline Granules Coated with a Polyelectrolyte Complex of Sodium Polyphosphate-Chitosan Yoshiaki Kawashimà, T. Handa, Akihide Kasai et al. · Journal of Pharmaceutical Sciences Open access	Mar 1985	169
6	Anti-inflammatory and Antitumor-Promoting Effects of the Triterpene Acids from the Leaves of Eriobotrya japonica Norihiro Banno, Toshihiro Akihisa, Harukuni Tokuda et al. · Biological and Pharmaceutical Bulletin Open access	2005	151
7	Mast cell tryptase and photoaging: possible involvement in the degradation of extra cellular matrix and basement membrane proteins Arunasiri Iddamalgoda, Quang Trong Le, Kenichi Ito et al. · Archives of Dermatological Research	29 Oct 2007	107
8	N‐Terminally extended human ubiquitin‐conjugating enzymes (E2s) mediate the ubiquitination of RING‐finger proteins, ARA54 and RNF8 Ken‐ichi Ito, Seiji Adachi, Reiko Iwakami et al. · European Journal of Biochemistry Open access	May 2001	99
9	Generation of KS-58 as the first K-Ras(G12D)-inhibitory peptide presenting anti-cancer activity in vivo Kotaro Sakamoto, Teruaki Masutani, Takatsugu Hirokawa · Scientific Reports Open access	10 Dec 2020	85
10	Melanogenesis Inhibitory, Anti-Inflammatory, and Chemopreventive Effects of Limonoids from the Seeds of Azadirachta indicia A. Juss. (Neem) Toshihiro Akihisa, Taisuke Noto, Akitomo Takahashi et al. · Journal of Oleo Science Open access	2009	84
11	Inhibitory Effects of Cucurbitane Glycosides and Other Triterpenoids from the Fruit of Momordica grosvenori on Epstein−Barr Virus Early Antigen Induced by Tumor Promoter 12-O-Tetradecanoylphorbol-13-acetate Motohiko Ukiya, Toshihiro Akihisa, Harukuni Tokuda et al. · Journal of Agricultural and Food Chemistry	4 Oct 2002	83
12	Cancer Chemopreventive Effects and Cytotoxic Activities of the Triterpene Acids from the Resin of Boswellia carteri Toshihiro Akihisa, Keiichi Tabata, Norihiro Banno et al. · Biological and Pharmaceutical Bulletin Open access	2006	75
13	Melanogenesis Inhibitory Activities of Iridoid-, Hemiterpene-, and Fatty Acid-glycosides from the Fruits of Morinda citrifolia (Noni) Toshihiro Akihisa, Ken-ichi Seino, Etsuyo Kaneko et al. · Journal of Oleo Science Open access	2010	70
14	Cynaropicrin from Cynara scolymus L. suppresses photoaging of skin by inhibiting the transcription activity of nuclear factor-kappa B Yuka Tanaka, Kiyotaka Tanaka, Hiroyuki Kojima et al. · Bioorganic & Medicinal Chemistry Letters	20 Nov 2012	69
15	Melanogenesis Inhibitory and Free Radical Scavenging Activities of Diarylheptanoids and Other Phenolic Compounds from the Bark of Acer nikoense Hiroyuki Akazawa, Toshihiro Akihisa, Yosuke Taguchi et al. · Biological and Pharmaceutical Bulletin Open access	2006	66
16	Magnolia ovovata extract and its active component magnolol prevent skin photoaging via inhibition of nuclear factor κB Kiyotaka Tanaka, Junichi Hasegawa, Kaori Asamitsu et al. · European Journal of Pharmacology	18 Feb 2007	57
17	GABA-synthesizing enzyme, GAD67, from dermal fibroblasts: Evidence for a new skin function Kenichi Ito, Kiyotaka Tanaka, Yukinobu Nishibe et al. · Biochimica et Biophysica Acta (BBA) - General Subjects	5 Oct 2006	56
18	The Melanogenesis-Inhibitory, Anti-Inflammatory, and Chemopreventive Effects of Limonoids in n-Hexane Extract of Azadirachta indica A. Juss. (Neem) Seeds Toshihiro Akihisa, Akitomo Takahashi, Takashi Kikuchi et al. · Journal of Oleo Science Open access	2011	54
19	Effects of Artichoke Leaf Extract on Acute Gastric Mucosal Injury in Rats Kazuo ISHIDA, Ryoji Kojima, Makoto Tsuboi et al. · Biological and Pharmaceutical Bulletin Open access	2010	51
20	Rapid determination of histamine and its metabolites in mice hair by ultra-performance liquid chromatography with time-of-flight mass spectrometry Hiroki Kawanishi, Toshimasa Toyo’oka, Kenichi Ito et al. · Journal of Chromatography A	15 Oct 2006	46
21	Extracellular Environment-Controlled Angiogenesis, and Potential Application for Peripheral Nerve Regeneration Shingo Saio, Kanna Konishi, Hirofumi Hohjoh et al. · International Journal of Molecular Sciences Open access	16 Oct 2021	45
22	GPNMB is expressed in human epidermal keratinocytes but disappears in the vitiligo lesional skin Kazal Boron Biswas, Aya Takahashi, Yukiko Mizutani et al. · Scientific Reports Open access	18 Mar 2020	41
23	The RING Finger Protein, RNF8, Interacts with Retinoid X Receptor α and Enhances Its Transcription-stimulating Activity Yukihiko Takano, Seiji Adachi, Masataka Okuno et al. · Journal of Biological Chemistry Open access	Apr 2004	41
24	Three New Cyclic Diarylheptanoids and Other Phenolic Compounds from the Bark of Myrica rubra and Their Melanogenesis Inhibitory and Radical Scavenging Activities Hiroyuki Akazawa, Yukiko Fujita, Norihiro Banno et al. · Journal of Oleo Science Open access	2010	39
25	Cytotoxic activity of Perilla frutescens var. japonica leaf extract is due to high concentrations of oleanolic and ursolic acids Toshihiro Akihisa, Satoshi Kamo, Taketo Uchiyama et al. · Journal of Natural Medicines	14 Aug 2006	36
26	Cucurbitane Glycosides from the Fruits of Siraitia grosvenorii and Their Inhibitory Effects on Epstein−Barr Virus Activation Toshihiro Akihisa, Yosuke Hayakawa, Harukuni Tokuda et al. · Journal of Natural Products	4 May 2007	36
27	Cynaropicrin from Cynara scolymus L. suppresses Porphyromonas gingivalis LPS-induced production of inflammatory cytokines in human gingival fibroblasts and RANKL-induced osteoclast differentiation in RAW264.7 cells Mayumi Hayata, Norihisa Watanabe, Noriaki Kamio et al. · Journal of Natural Medicines	14 Sep 2018	33
28	Cytotoxic and Melanogenesis‐Inhibitory Activities of Limonoids from the Leaves of Azadirachta indica (Neem) Mio Takagi, Yosuke Tachi, Jie Zhang et al. · Chemistry & Biodiversity	Mar 2014	33
29	Melanin production through novel processing of proopiomelanocortin in the extracellular compartment of the auricular skin of C57BL/6 mice after UV-irradiation Hiroyuki Yamamoto, Tomohiro Yamane, Kazuaki Iguchi et al. · Scientific Reports Open access	29 Sep 2015	28
30	Glycosidic Inhibitors of Melanogenesis from Leaves of Passiflora edulis Jie Zhang, Ryosuke Koike, Ayako Yamamoto et al. · Chemistry & Biodiversity	Oct 2013	27
31	Evaluation of the effect of salmon nasal proteoglycan on biomarkers for cartilage metabolism in individuals with knee joint discomfort: A randomized double-blind placebo-controlled clinical study Akihito Tomonaga, Tatsuji Takahashi, Yuka Tanaka et al. · Experimental and Therapeutic Medicine Open access	11 May 2017	25
32	The K-Ras(G12D)-inhibitory peptide KS-58 suppresses growth of murine CT26 colorectal cancer cell-derived tumors Kotaro Sakamoto, Bangzhong Lin, Kazuto Nunomura et al. · Scientific Reports Open access	17 May 2022	22
33	The protective effect of Centella asiatica and its constituent, araliadiol on neuronal cell damage and cognitive impairment Honoka Fujimori, Takuya Ohba, Masashi Mikami et al. · Journal of Pharmacological Sciences Open access	11 Nov 2021	22
34	Biological Activities of Triterpenoids and Phenolic Compounds from Myrica cerifera Bark Jie Zhang, Satoshi Yamada, Eri Ogihara et al. · Chemistry & Biodiversity	5 Aug 2016	22
35	Potent Protein Glycation Inhibition of Plantagoside inPlantago majorSeeds Nobuyasu Matsuura, Tadashi Aradate, Chihiro Kurosaka et al. · BioMed Research International Open access	2014	21
36	Vasoactive intestinal peptide–VIPR2 signaling regulates tumor cell migration S Asano, Misa Yamasaka, Kairi Ozasa et al. · Frontiers in Oncology Open access	27 Sep 2022	20
37	Hair analysis of histamine and several metabolites in C3H/HeNCrj mice by ultra performance liquid chromatography with electrospray ionization time-of-flight mass spectrometry (UPLC-ESI-TOF-MS): Influence of hair cycle and age Hiroki Kawanishi, Toshimasa Toyo’oka, Kenichi Ito et al. · Clinica Chimica Acta	29 Nov 2006	19
38	The inhibitory effect of the components of Cornus officinalis on melanogenesis Yasuhiko Nawa, Junko Endo, Tomihisa Ohta · International Journal of Cosmetic Science	8 Sep 2008	17
39	Vasoactive intestinal peptide receptor 2 signaling promotes breast cancer cell proliferation by enhancing the ERK pathway S Asano, Ami Ono, Kotaro Sakamoto et al. · Peptides	2 Jan 2023	16
40	Generation of KS-133 as a Novel Bicyclic Peptide with a Potent and Selective VIPR2 Antagonist Activity that Counteracts Cognitive Decline in a Mouse Model of Psychiatric Disorders Kotaro Sakamoto, Lu Chen, Tatsunori Miyaoka et al. · Frontiers in Pharmacology Open access	4 Nov 2021	16
41	GPNMB Extracellular Fragment Protects Melanocytes from Oxidative Stress by Inhibiting AKT Phosphorylation Independent of CD44 Qianqian Wang, Y. Kuroda, Lingli Yang et al. · International Journal of Molecular Sciences Open access	7 Oct 2021	16
42	Generation of KS-487 as a novel LRP1-binding cyclic peptide with higher affinity, higher stability and BBB permeability Kotaro Sakamoto · Biochemistry and Biophysics Reports Open access	8 Oct 2022	15
43	Acorus calamus extract and its component α-asarone attenuate murine hippocampal neuronal cell death induced by l -glutamate and tunicamycin Masashi Mikami, Takuya Ohba, Yuta Yoshino et al. · Bioscience Biotechnology and Biochemistry	3 Feb 2021	15
44	Improvement of Learning and Memory in Senescence-Accelerated Mice by S-Allylcysteine in Mature Garlic Extract Masakazu Hashimoto, T. NAKAI, Teruaki Masutani et al. · Nutrients Open access	19 Jun 2020	15
45	Nanoformulation of the K-Ras(G12D)-inhibitory peptide KS-58 suppresses colorectal and pancreatic cancer-derived tumors Kotaro Sakamoto, Yun Kai Qi, Eijiro Miyako · Scientific Reports Open access	10 Jan 2023	13
46	Effects of watercress extract fraction on R‐spondin 1‐mediated growth of human hair Masakazu Hashimoto, Yuka Kawai, Teruaki Masutani et al. · International Journal of Cosmetic Science	8 Feb 2022	13
47	The VIPR2-selective antagonist KS-133 changes macrophage polarization and exerts potent anti-tumor effects as a single agent and in combination with an anti-PD-1 antibody Kotaro Sakamoto, Wararat Kittikulsuth, Eijiro Miyako et al. · PLoS ONE Open access	5 Jul 2023	12
48	Ellagitannins from Rosa roxburghii suppress poly(I:C)-induced IL-8 production in human keratinocytes Satoru Takayama, Miho Kawanishi, Kosei Yamauchi et al. · Journal of Natural Medicines	8 Apr 2021	12
49	Cyclic Peptides KS-133 and KS-487 Multifunctionalized Nanoparticles Enable Efficient Brain Targeting for Treating Schizophrenia Kotaro Sakamoto, Seigo Iwata, Zihao Jin et al. · JACS Au Open access	20 Jun 2024	11
50	Juniper berry extract containing Anthricin and Yatein suppresses lipofuscin accumulation in human epidermal keratinocytes through proteasome activation, increases brightness and decreases spots in human skin Kotaro Sakamoto, Runa Fujimoto, Satoshi Nakagawa et al. · International Journal of Cosmetic Science	15 Jun 2023	11

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.