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Institution · Idera Pharmaceuticals (United States)

Most cited papers from Idera Pharmaceuticals (United States)

Idera Pharmaceuticals (United States)

What are the most cited papers from Idera Pharmaceuticals (United States)?

The most cited paper from Idera Pharmaceuticals (United States) is "Telbivudine versus Lamivudine in Patients with Chronic Hepatitis B" (Ching‐Lung Lai, Edward John Gane, Yun‐Fan Liaw et al., 2007), with 776 citations. Next come "A mechanistic role for cardiac myocyte apoptosis in heart failure" (749) and "Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome" (587).

Showing 50 of 59 papers. Every paper with more than 68 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Telbivudine versus Lamivudine in Patients with Chronic Hepatitis B Ching‐Lung Lai, Edward John Gane, Yun‐Fan Liaw et al. · New England Journal of Medicine Open access 19 Dec 2007 776
2 A mechanistic role for cardiac myocyte apoptosis in heart failure Detlef Wencker, Madhulika Chandra, Khanh T. V. Nguyen et al. · Journal of Clinical Investigation Open access 15 May 2003 749
3 Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome Vanessa S. Marsden, Liam J. O’Connor, Lorraine Ann O’Reilly et al. · Nature 25 Sep 2002 587
4 2-Year GLOBE Trial Results: Telbivudine Is Superior to Lamivudine in Patients With Chronic Hepatitis B Yun‐Fan Liaw, Edward John Gane, Nancy Leung et al. · Gastroenterology 22 Nov 2008 566
5 Role for Akt3/Protein Kinase Bγ in Attainment of Normal Brain Size Rachael Easton, Han Cho, Kristin I. Roovers et al. · Molecular and Cellular Biology Open access 14 Feb 2005 555
6 HBXIP functions as a cofactor of survivin in apoptosis suppression Hiroyuki Marusawa, Shu‐ichi Matsuzawa, Kate Welsh et al. · The EMBO Journal Open access 28 May 2003 435
7 A 1-Year Trial of Telbivudine, Lamivudine, and the Combination in Patients With Hepatitis B e Antigen—Positive Chronic Hepatitis B Ching‐Lung Lai, Nancy Leung, Eng Kiong Teo et al. · Gastroenterology Open access Aug 2005 396
8 In situ immunodetection of activated caspase-3 in apoptotic neurons in the developing nervous system Anu N. Srinivasan, Kevin A. Roth, Robert O. Sayers et al. · Cell Death and Differentiation Dec 1998 370
9 Cell-specific Induction of Apoptosis by Microinjection of Cytochrome c Feng Li, Anu N. Srinivasan, Yu Wang et al. · Journal of Biological Chemistry Open access Nov 1997 353
10 Fas-induced Activation of the Cell Death-related Protease CPP32 Is Inhibited by Bcl-2 and by ICE Family Protease Inhibitors Robert C. Armstrong, Teresa Aja, Jialing Xiang et al. · Journal of Biological Chemistry Open access Jul 1996 319
11 Activation of the CED3/ICE-Related Protease CPP32 in Cerebellar Granule Neurons Undergoing Apoptosis But Not Necrosis Robert C. Armstrong, Teresa Aja, Kim Hoang et al. · Journal of Neuroscience Open access 15 Jan 1997 282
12 Omega-3 free fatty acids for the treatment of severe hypertriglyceridemia: The EpanoVa fOr Lowering Very high triglyceridEs (EVOLVE) trial John J.P. Kastelein, Kevin Carl Maki, Andrey V. Susekov et al. · Journal of clinical lipidology Open access 15 Oct 2013 233
13 Inhibition of Cardiac Myocyte Apoptosis Improves Cardiac Function and Abolishes Mortality in the Peripartum Cardiomyopathy of Gαq Transgenic Mice Yukihiro Hayakawa, Madhulika Chandra, Wenfeng Miao et al. · Circulation 25 Nov 2003 225
14 Human IAP-Like Protein Regulates Programmed Cell Death Downstream of Bcl-x L and Cytochrome c Colin S. Duckett, Feng Li, Yu Wang et al. · Molecular and Cellular Biology Open access 1998 219
15 Starting the fight in the tumor: expert recommendations for the development of human intratumoral immunotherapy (HIT-IT) Aurélien Marabelle et al. · Annals of Oncology Open access 6 Oct 2018 216
16 Regulation of the Apaf-1/Caspase-9 Apoptosome by Caspase-3 and XIAP Hua Zou, Ruomei Yang, Junshan Hao et al. · Journal of Biological Chemistry Open access 28 Feb 2003 214
17 Baseline characteristics and early on-treatment response predict the outcomes of 2years of telbivudine treatment of chronic hepatitis B Stefan Zeuzem, Edward John Gane, Yun‐Fan Liaw et al. · Journal of Hepatology 13 Feb 2009 196
18 Treatment of Hepatitis B e Antigen–Positive Chronic Hepatitis with Telbivudine or Adefovir Henry Lik‐Yuen Chan, E. Jenny Heathcote, Patrick Marcellin et al. · Annals of Internal Medicine 4 Dec 2007 192
19 A novel omega-3 free fatty acid formulation has dramatically improved bioavailability during a low-fat diet compared with omega-3-acid ethyl esters: The ECLIPSE (Epanova® compared to Lovaza® in a pharmacokinetic single-dose evaluation) study Michael H Davidson, Judith Johnson, Michael W. Rooney et al. · Journal of clinical lipidology 24 Jan 2012 191
20 Synthesis and Pharmacokinetics of Valopicitabine (NM283), an Efficient Prodrug of the Potent Anti-HCV Agent 2‘-C-Methylcytidine Claire Pierra, Agnès Amador, S. Benzaria et al. · Journal of Medicinal Chemistry 6 Oct 2006 190
21 Open science discovery of potent noncovalent SARS-CoV-2 main protease inhibitors Melissa L. Boby et al. · Science Open access218 authors 9 Nov 2023 188
22 Preclinical assessment of galunisertib (LY2157299 monohydrate), a first-in-class transforming growth factor-β receptor type I inhibitor Jonathan M. Yingling et al. · Oncotarget Open access 31 Dec 2017 183
23 Synthesis and Biological Evaluation of Aryl-phospho-indole as Novel HIV-1 Non-nucleoside Reverse Transcriptase Inhibitors François-René Alexandre, Agnès Amador, Stéphanie Bot et al. · Journal of Medicinal Chemistry 13 Dec 2010 181
24 Antibacterial drug discovery: is it all downhill from here? Steven J. Projan, David M. Shlaes · Clinical Microbiology and Infection Open access 2004 171
25 Telbivudine versus lamivudine in Chinese patients with chronic hepatitis B: Results at 1 year of a randomized, double-blind trial Jinlin Hou et al. · Hepatology 14 Dec 2007 163
26 Bcl-xL Functions Downstream of Caspase-8 to Inhibit Fas- and Tumor Necrosis Factor Receptor 1-induced Apoptosis of MCF7 Breast Carcinoma Cells Anu N. Srinivasan, Feng Li, Angela Wong et al. · Journal of Biological Chemistry Open access Feb 1998 160
27 Dimerization Properties of Human BAD Sabine Ottilie, José-Luis Díaz, William A. Horne et al. · Journal of Biological Chemistry Open access Dec 1997 149
28 Inhibition of 14q32 MicroRNAs miR-329, miR-487b, miR-494, and miR-495 Increases Neovascularization and Blood Flow Recovery After Ischemia Sabine M. J. Welten, Antonius J. N. M. Bastiaansen, Rob C. M. de Jong et al. · Circulation Research 2 Aug 2014 142
29 A Common Binding Site Mediates Heterodimerization and Homodimerization of Bcl-2 Family Members José-Luis Díaz, Tilman Oltersdorf, William A. Horne et al. · Journal of Biological Chemistry Open access Apr 1997 130
30 Preclinical Characterization of AEG35156/GEM 640, a Second-Generation Antisense Oligonucleotide Targeting X-Linked Inhibitor of Apoptosis Eric Charles LaCasse, Gabriele Cherton-Horvat, Kimberley E. Hewitt et al. · Clinical Cancer Research Sep 2006 129
31 Synthetic agonists of Toll-like receptors 7, 8 and 9 Sudhir Agrawal, Ekambar R. Kandimalla · Biochemical Society Transactions 23 Nov 2007 126
32 Notch-Regulated Ankyrin-Repeat Protein Inhibits Notch1 Signaling: Multiple Notch1 Signaling Pathways Involved In T Cell Development Theodore J. Yun, Michael John Bevan · The Journal of Immunology Open access Jun 2003 115
33 A Highly Bioavailable Omega-3 Free Fatty Acid Formulation Improves the Cardiovascular Risk Profile in High-Risk, Statin-Treated Patients With Residual Hypertriglyceridemia (the ESPRIT Trial) Kevin Carl Maki, David G. Orloff, Stephen James Nicholls et al. · Clinical Therapeutics 30 Aug 2013 105
34 Characterization of IDN-6556 (3-{2-(2-tert-Butyl-phenylaminooxalyl)-amino]-propionylamino}-4-oxo-5-(2,3,5,6-tetrafluoro-phenoxy)-pentanoic Acid): a Liver-Targeted Caspase Inhibitor Niel C. Hoglen, Long-Shiuh Chen, Craig D. Fisher et al. · Journal of Pharmacology and Experimental Therapeutics 22 Apr 2004 99
35 IMO-8400, a toll-like receptor 7, 8, and 9 antagonist, demonstrates clinical activity in a phase 2a, randomized, placebo-controlled trial in patients with moderate-to-severe plaque psoriasis Deepak M.W. Balak, Martijn B. A. van Doorn, Robert D. Arbeit et al. · Clinical Immunology 20 Nov 2016 98
36 A dose-finding study of once-daily oral telbivudine in HBeAg-positive patients with chronic hepatitis B virus infection Ching‐Lung Lai, Seng Gee Lim, Nathaniel A. Brown et al. · Hepatology Open access 30 Aug 2004 98
37 Steady-state bioavailability of prescription omega-3 on a low-fat diet is significantly improved with a free fatty acid formulation compared with an ethyl ester formulation: the ECLIPSE II study Elliot M. Offman, Ted Marenco, Sandy Ferber et al. · Vascular Health and Risk Management Open access Oct 2013 93
38 Suppression of Molecular Inflammatory Pathways by Toll-Like Receptor 7, 8, and 9 Antagonists in a Model of IL-23-Induced Skin Inflammation Mayte Suárez‐Fariñas, Robert D. Arbeit, Weiwen Jiang et al. · PLoS ONE Open access 27 Dec 2013 93
39 Conjugated Linoleic Acid Blocks Estrogen Signaling in Human Breast Cancer Cells Prasong Tanmahasamut, Jingbo Liu, Lawrence B. Hendry et al. · Journal of Nutrition Open access Mar 2004 92
40 Preclinical evaluation of 90Y-labeled anti-CD20 monoclonal antibody for treatment of non-Hodgkin's lymphoma. Paul C. Chinn, John E. Leonard, Jay A. Rosenberg et al. · International Journal of Oncology Nov 1999 91
41 Self-assembled thermoresponsive nanostructures of hyaluronic acid conjugates for osteoarthritis therapy Pierre Maudens, Sophie Meyer, Christian Alexander Seemayer et al. · Nanoscale Open access 8 Dec 2017 90
42 Omega-3 fatty acids Michael H. Davidson · Current Opinion in Lipidology Nov 2013 88
43 Novel Toll-Like Receptor 9 Agonist Induces Epidermal Growth Factor Receptor (EGFR) Inhibition and Synergistic Antitumor Activity with EGFR Inhibitors Vincenzo Damiano, Rosa Caputo, Roberto Bianco et al. · Clinical Cancer Research 15 Jan 2006 88
44 A Toll-Like Receptor 7, 8, and 9 Antagonist Inhibits Th1 and Th17 Responses and Inflammasome Activation in a Model of IL-23-Induced Psoriasis Weiwen Jiang, Fu‐Gang Zhu, Lakshmi Bhagat et al. · Journal of Investigative Dermatology Open access 31 Jan 2013 87
45 “Primatization” of Recombinant Antibodies for Immunotherapy of Human Diseases: A Macaque/Human Chimeric Antibody Against Human CD4 Roland Newman, J.O. Alberts, Darrell R. Anderson et al. · Nature Biotechnology Nov 1992 86
46 Cooperative Inhibition of Renal Cancer Growth by Anti-Epidermal Growth Factor Receptor Antibody and Protein Kinase A Antisense Oligonucleotide Fortunato Ciardiello, Rosa Caputo, Roberto Bianco et al. · JNCI Journal of the National Cancer Institute 15 Jul 1998 85
47 Heat shock protein 70 prevents secretagogue-induced cell injury in the pancreas by preventing intracellular trypsinogen activation Lakshmi Bhagat, Vijay P. Singh, Antti J. Hietaranta et al. · Journal of Clinical Investigation Open access Jul 2000 84
48 Antisense oligonucleotides targeting the epidermal growth factor receptor inhibit proliferation, induce apoptosis, and cooperate with cytotoxic drugs in human cancer cell lines Fortunato Ciardiello, Rosa Caputo, Teresa Troiani et al. · International Journal of Cancer Open access 2001 84
49 Phase 1 studies of the safety and immunogenicity of electroporated HER2/CEA DNA vaccine followed by adenoviral boost immunization in patients with solid tumors Claudia Marcela Diaz, Alberto Chiappori, Luigi Aurisicchio et al. · Journal of Translational Medicine Open access 8 Mar 2013 78
50 Discovery of the Aryl-phospho-indole IDX899, a Highly Potent Anti-HIV Non-nucleoside Reverse Transcriptase Inhibitor Cyril B. Dousson et al. · Journal of Medicinal Chemistry 23 Jan 2016 76

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.