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Most cited papers from IJ Research (United States)

What are the most cited papers from IJ Research (United States)?

The most cited paper from IJ Research (United States) is "The inflammatory reflex" (Kevin J. Tracey, 2002), with 3,734 citations. Next come "Nicotinic acetylcholine receptor α7 subunit is an essential regulator of inflammation" (3,242) and "Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupus" (2,283).

Showing 50 of 60 papers. Every paper with more than 164 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 The inflammatory reflex Kevin J. Tracey · Nature Dec 2002 3,734
2 Nicotinic acetylcholine receptor α7 subunit is an essential regulator of inflammation Hong Tian Wang, Man Yu, Mahendar Ochani et al. · Nature 22 Dec 2002 3,242
3 Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupus Emily C. Baechler, Franak Batliwalla, George Karypis et al. · Proceedings of the National Academy of Sciences Open access 25 Feb 2003 2,283
4 Definition of clinically relevant non‐major bleeding in studies of anticoagulants in atrial fibrillation and venous thromboembolic disease in non‐surgical patients: communication from the SSC of the ISTH Scott S. Kaatz, Ahmad Danesh, Alex C. Spyropoulos et al. · Journal of Thrombosis and Haemostasis Open access 11 Sep 2015 1,422
5 Cholinergic agonists inhibit HMGB1 release and improve survival in experimental sepsis Hong Tian Wang, Hong Liao, Mahendar Ochani et al. · Nature Medicine 24 Oct 2004 1,187
6 Randomized controlled trial of intraputamenal glial cell line–derived neurotrophic factor infusion in Parkinson disease Anthony E. Lang et al. · Annals of Neurology 20 Jan 2006 988
7 Deep Pyramid Convolutional Neural Networks for Text Categorization Rie Johnson, Tong Zhang Conference paperOpen access 2017 840
8 The Cholinergic Anti-inflammatory Pathway: A Missing Link in Neuroimmunomodulation Valentin A. Pavlov, Hong Tian Wang, Christopher J. Czura et al. · Molecular Medicine Open access May 2003 768
9 Resveratrol Promotes Clearance of Alzheimer's Disease Amyloid-β Peptides Philippe Marambaud, Haitian Zhao, Peter J. Davies · Journal of Biological Chemistry Open access 15 Sep 2005 747
10 Genetic Association of the R620W Polymorphism of Protein Tyrosine Phosphatase PTPN22 with Human SLE Chieko Kyogoku et al. · The American Journal of Human Genetics Open access 3 Aug 2004 672
11 Better Tests, Better Care: Improved Diagnostics for Infectious Diseases Angela M. Caliendo, David N. Gilbert, Christine C. Ginocchio et al. · Clinical Infectious Diseases Open access 6 Nov 2013 645
12 Analysis of Families in the Multiple Autoimmune Disease Genetics Consortium (MADGC) Collection: the PTPN22 620W Allele Associates with Multiple Autoimmune Phenotypes Lindsey A. Criswell, Kirsten A. Pfeiffer, Raymond F. Lum et al. · The American Journal of Human Genetics Open access 29 Mar 2005 604
13 Ethyl pyruvate prevents lethality in mice with established lethal sepsis and systemic inflammation Luis Ulloa, Mahendar Ochani, Huan Yang et al. · Proceedings of the National Academy of Sciences Open access 3 Sep 2002 594
14 Refining the complex rheumatoid arthritis phenotype based on specificity of the HLA–DRB1 shared epitope for antibodies to citrullinated proteins Tom W. J. Huizinga, Christopher I. Amos, Annette H M van der Helm–van Mil et al. · Arthritis & Rheumatism 27 Oct 2005 593
15 In vivo measurements document the dynamic cellular kinetics of chronic lymphocytic leukemia B cells Bradley T. Messmer, Davorka Messmer, Steven L. Allen et al. · Journal of Clinical Investigation Open access Mar 2005 583
16 Replication of Putative Candidate-Gene Associations with Rheumatoid Arthritis in >4,000 Samples from North America and Sweden: Association of Susceptibility with PTPN22, CTLA4, and PADI4 Robert M. Plenge, Leonid Padyukov, Elaine F. Remmers et al. · The American Journal of Human Genetics Open access 7 Nov 2005 562
17 High Mobility Group Box Protein 1: An Endogenous Signal for Dendritic Cell Maturation and Th1 Polarization Davorka Messmer, Huan Yang, Gloria Telusma et al. · The Journal of Immunology Jul 2004 448
18 The ‘cytokine profile’: a code for sepsis Luis Ulloa, Kevin J. Tracey · Trends in Molecular Medicine Review 13 Jan 2005 445
19 Extracellular role of HMGB1 in inflammation and sepsis Haichao Wang, Huan Yang, Kevin J. Tracey · Journal of Internal Medicine 10 Feb 2004 439
20 Persistent elevation of high mobility group box-1 protein (HMGB1) in patients with severe sepsis and septic shock* Jonas Sundén‐Cullberg, Anna Norrby‐Teglund, Ari Rouhiainen et al. · Critical Care Medicine 28 Feb 2005 430
21 Functional variants in the LRRK2 gene confer shared effects on risk for Crohn’s disease and Parkinson’s disease Ken Y. Hui et al. · Science Translational Medicine Open access 10 Jan 2018 419
22 RAGE and arthritis: the G82S polymorphism amplifies the inflammatory response Marion A. Hofmann, Steven Drury, Barry Ian Hudson et al. · Genes and Immunity May 2002 388
23 B Cell Chronic Lymphocytic Leukemia: Lessons Learned from Studies of the B Cell Antigen Receptor Nicholas Chiorazzi, Manlio Ferrarini · Annual Review of Immunology Review 3 Mar 2003 377
24 JAK/STAT1 signaling promotes HMGB1 hyperacetylation and nuclear translocation Ben Lü, Daniel James Antoine, Kevin Kwan et al. · Proceedings of the National Academy of Sciences Open access 27 Jan 2014 372
25 Structural Basis for the Proinflammatory Cytokine Activity of High Mobility Group Box 1 Jianhua Li, Riikka Kokkola, SIAMAK S. TABIBZADEH et al. · Molecular Medicine Open access 2003 367
26 A functional promoter polymorphism in the macrophage migration inhibitory factor (MIF) gene associated with disease severity in rheumatoid arthritis John Andrew Baugh, Shilpa Chitnis, Seamas C. Donnelly et al. · Genes and Immunity May 2002 363
27 IFN-γ Induces High Mobility Group Box 1 Protein Release Partly Through a TNF-Dependent Mechanism Beatriz Rendon-Mitchell, Mahendar Ochani, Jianhua Li et al. · The Journal of Immunology Apr 2003 357
28 B-cell chronic lymphocytic leukemia cells express a surface membrane phenotype of activated, antigen-experienced B lymphocytes Rajendra N. Damle · Blood 13 May 2002 345
29 Functional annotation of a novel NFKB1 promoter polymorphism that increases risk for ulcerative colitis Amir S. Karban, Toshihiko Okazaki, Carolien I. M. Panhuysen et al. · Human Molecular Genetics Open access 15 Dec 2003 337
30 Successful treatment of collagen‐induced arthritis in mice and rats by targeting extracellular high mobility group box chromosomal protein 1 activity Riikka Kokkola, J. Li, Erik Sundberg et al. · Arthritis & Rheumatism Jul 2003 327
31 ISO-1 Binding to the Tautomerase Active Site of MIF Inhibits Its Pro-inflammatory Activity and Increases Survival in Severe Sepsis Yousef Al‐Abed, Darrin R. Dabideen, Bayan Aljabari et al. · Journal of Biological Chemistry Open access 23 Aug 2005 319
32 TMP21 is a presenilin complex component that modulates γ-secretase but not ɛ-secretase activity Fusheng Chen, Hiroshi Hasegawa, Gerold Schmitt‐Ulms et al. · Nature Apr 2006 301
33 Reassessing the value of varicocelectomy as a treatment for male subfertility with a new meta-analysis Joel L. Marmar, Ashok Kumar Agarwal, Sushil A. Prabakaran et al. · Fertility and Sterility Open access 17 Apr 2007 296
34 Integration with the human genome of peptide sequences obtained by high-throughput mass spectrometry Frank Desiere et al. · Genome biology Open access 10 Dec 2004 295
35 High mobility group box chromosomal protein 1: A novel proinflammatory mediator in synovitis Riikka Kokkola, Erik Sundberg, A.‐K. Ulfgren et al. · Arthritis & Rheumatism Oct 2002 293
36 The p53-dependent effects of macrophage migration inhibitory factor revealed by gene targeting Günter Fingerle‐Rowson, Oleksi Petrenko, Christine Noel Metz et al. · Proceedings of the National Academy of Sciences Open access 23 Jul 2003 285
37 Roles of the Rac1 and Rac3 GTPases in human tumor cell invasion Amanda Y. Chan, Salvatore J. Coniglio, Ya-yu Chuang et al. · Oncogene 18 Jul 2005 257
38 Autonomic neural regulation of immunity Christopher J. Czura, Kevin J. Tracey · Journal of Internal Medicine 17 Jan 2005 256
39 Syndrome of occipitoatlantoaxial hypermobility, cranial settling, and Chiari malformation Type I in patients with hereditary disorders of connective tissue Thomas H. Milhorat, Paolo A. Bolognese, Misao Nishikawa et al. · Journal of Neurosurgery Spine Dec 2007 254
40 Role of Rho family GTPases in epithelial morphogenesis Linda Van Aelst, Marc H. Symons · Genes & Development Open access May 2002 239
41 Fibrocytes: a unique cell population implicated in wound healing Christine Noel Metz · Cellular and Molecular Life Sciences Open access Jul 2003 238
42 PTPN22 Genetic Variation: Evidence for Multiple Variants Associated with Rheumatoid Arthritis Victoria E. H. Carlton, Xiaolan Hu, Anand P. Chokkalingam et al. · The American Journal of Human Genetics Open access 8 Sep 2005 235
43 Inflammatory cytokines and anorexia nervosa: A meta-analysis of cross-sectional and longitudinal studies Marco Solmi, Nicola Veronese, Angela Favaro et al. · Psychoneuroendocrinology Review 9 Oct 2014 224
44 Genome-wide association study of Tourette's syndrome Jeremiah M. Scharf et al. · Molecular Psychiatry Open access 14 Aug 2012 218
45 The emerging role of interferon in human systemic lupus erythematosus Emily C. Baechler, Peter K. Gregersen, Timothy W. Behrens · Current Opinion in Immunology Review 5 Oct 2004 212
46 Regulation of anti–cyclic citrullinated peptide antibodies in rheumatoid arthritis: Contrasting effects of HLA–DR3 and the shared epitope alleles Patricia Irigoyen, Annette T. Lee, Mark H. Wener et al. · Arthritis & Rheumatism 30 Nov 2005 211
47 The PTPN22 R620W polymorphism associates with RF positive rheumatoid arthritis in a dose-dependent manner but not with HLA-SE status A T Lee, Wentian Li, Anthony Liew et al. · Genes and Immunity 23 Dec 2004 206
48 Stereotactic body radiotherapy for localized prostate cancer: disease control and quality of life at 6 years Alan Jay Katz, M. Santoro, Fred Diblasio et al. · Radiation Oncology Open access 13 May 2013 203
49 Imaging Evidence and Recommendations for Traumatic Brain Injury: Conventional Neuroimaging Techniques Max Wintermark, Pina C. Sanelli, Yoshimi Anzai et al. · Journal of the American College of Radiology 25 Nov 2014 199
50 BLM Heterozygosity and the Risk of Colorectal Cancer Stephen B. Gruber et al. · Science 19 Sep 2002 198

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.