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Most cited papers from Institute on Aging

What are the most cited papers from Institute on Aging?

The most cited paper from Institute on Aging is "A Short Physical Performance Battery Assessing Lower Extremity Function: Association With Self-Reported Disability and Prediction of Mortality and Nursing Home Admission" (Jack M. Guralnik, E. M. Simonsick, Luigi Ferrucci et al., 1994), with 9,940 citations. Next come "Ubiquitinated TDP-43 in Frontotemporal Lobar Degeneration and Amyotrophic Lateral Sclerosis" (6,756) and "The MOS social support survey" (6,738).

Showing 50 of 60 papers. Every paper with more than 1,416 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 A Short Physical Performance Battery Assessing Lower Extremity Function: Association With Self-Reported Disability and Prediction of Mortality and Nursing Home Admission Jack M. Guralnik, E. M. Simonsick, Luigi Ferrucci et al. · Journal of Gerontology Mar 1994 9,940
2 Ubiquitinated TDP-43 in Frontotemporal Lobar Degeneration and Amyotrophic Lateral Sclerosis Manuela Neumann, Deepak M. Sampathu, Linda K. Kwong et al. · Science 5 Oct 2006 6,756
3 The MOS social support survey Cathy Donald Sherbourne, Anita L. Stewart · Social Science & Medicine 1991 6,738
4 Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) Daniel J. Klionsky et al. · Autophagy Open access2,467 authors 2 Jan 2016 6,023
5 Mitochondrial Reactive Oxygen Species (ROS) and ROS-Induced ROS Release Dmitry B. Zorov, Magdalena Juhaszova, Steven J. Sollott · Physiological Reviews ReviewOpen access Jul 2014 5,423
6 Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia Katya Rascovsky et al. · Brain Open access 2 Aug 2011 5,386
7 Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade Clifford R. Jack, David S. Knopman, William J. Jagust et al. · The Lancet Neurology Open access 15 Dec 2009 4,880
8 Tracking pathophysiological processes in Alzheimer's disease: an updated hypothetical model of dynamic biomarkers Clifford R. Jack, David S. Knopman, William J. Jagust et al. · The Lancet Neurology Open access 16 Jan 2013 4,516
9 Untangling the Concepts of Disability, Frailty, and Comorbidity: Implications for Improved Targeting and Care Linda P. Fried, Luigi Ferrucci, Jonathan D. Darer et al. · The Journals of Gerontology Series A Open access Mar 2004 4,107
10 Autophagy regulates lipid metabolism Rajat Singh, Susmita Kaushik, Yongjun Wang et al. · Nature Open access Apr 2009 4,022
11 Personality trait structure as a human universal. Robert R. McCrae, Paul T. Costa · American Psychologist May 1997 3,920
12 Cellular Senescence: Defining a Path Forward Vassilis G. Gorgoulis et al. · Cell Open access Oct 2019 3,322
13 National Institute on Aging–Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease Bradley T. Hyman, Creighton H. Phelps, Thomas G. Beach et al. · Alzheimer s & Dementia Open access 2012 3,246
14 Pathways towards and away from Alzheimer's disease Mark P. Mattson · Nature Open access 4 Aug 2004 3,075
15 National Institute on Aging–Alzheimer’s Association guidelines for the neuropathologic assessment of Alzheimer’s disease: a practical approach Thomas Jude Montine, Creighton H. Phelps, Thomas G. Beach et al. · Acta Neuropathologica Open access 19 Nov 2011 2,988
16 Know Thyself and Become What You Are: A Eudaimonic Approach to Psychological Well-Being Carol Diane Ryff, Burton H. Singer · Journal of Happiness Studies 4 Oct 2006 2,932
17 Longitudinal Effects of Aging on Serum Total and Free Testosterone Levels in Healthy Men Sherman Mitchell Harman, E. Jeffrey Metter, Jordan D. Tobin et al. · The Journal of Clinical Endocrinology & Metabolism Open access Feb 2001 2,701
18 Pathological α-Synuclein Transmission Initiates Parkinson-like Neurodegeneration in Nontransgenic Mice Kelvin C. Luk, Victoria M. Kehm, Jenna C. Carroll et al. · Science Open access 15 Nov 2012 2,671
19 New insights into the genetic etiology of Alzheimer’s disease and related dementias Céline Bellenguez et al. · Nature Genetics Open access1,266 authors Apr 2022 2,608
20 Cloning of the Gene Containing Mutations that Cause PARK8-Linked Parkinson's Disease Coro Paisán-Ruı́z et al. · Neuron Open access Nov 2004 2,463
21 Focus Groups David L. Morgan · Annual Review of Sociology Review Aug 1996 2,344
22 Cellular response to oxidative stress: Signaling for suicide and survival* Jennifer L. Martindale, Nikki J. Holbrook · Journal of Cellular Physiology Open access 24 May 2002 2,327
23 Synapse Loss and Microglial Activation Precede Tangles in a P301S Tauopathy Mouse Model Yasumasa Yoshiyama, Makoto Higuchi, Bin Zhang et al. · Neuron Open access Feb 2007 2,326
24 Two Shorter Forms of the CES-D Depression Symptoms Index Frank J. Kohout, Lisa F. Berkman, Denis A. Evans et al. · Journal of Aging and Health May 1993 2,320
25 Evidence Suggesting That a Chronic Disease Self-Management Program Can Improve Health Status While Reducing Hospitalization Kate R. Lorig, David S. Sobel, Anita L. Stewart et al. · Medical Care 1999 2,287
26 Tau-mediated neurodegeneration in Alzheimer's disease and related disorders Carlo Ballatore, Virginia M.‐Y. Lee, John Q. Trojanowski · Nature reviews. Neuroscience Review 8 Aug 2007 2,217
27 Mitochondrial DNA Mutations, Oxidative Stress, and Apoptosis in Mammalian Aging Gregory C. Kujoth, Asimina Hiona, Thomas D. Pugh et al. · Science 14 Jul 2005 2,192
28 Correlation of Alzheimer Disease Neuropathologic Changes With Cognitive Status: A Review of the Literature Peter T. Nelson et al. · Journal of Neuropathology & Experimental Neurology Open access 6 Apr 2012 2,144
29 Cerebrospinal fluid biomarker signature in Alzheimer's disease neuroimaging initiative subjects Leslie M. Shaw, Hugo Vanderstichele, Malgorzata Elzbieta Knapik-Czajka et al. · Annals of Neurology Open access 19 Mar 2009 2,124
30 Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk Georg Ehret et al. · Nature Open access346 authors 9 Sep 2011 2,085
31 Gait speed at usual pace as a predictor of adverse outcomes in community-dwelling older people an International Academy on Nutrition and Aging (IANA) Task Force Gabor Abellán van Kan, Yves Rolland, Sandrine Andrieu et al. · The journal of nutrition health & aging Open access Dec 2009 2,013
32 Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease Cardiogenics et al. · Nature Genetics Open access167 authors 6 Mar 2011 1,959
33 Histone H4-K16 Acetylation Controls Chromatin Structure and Protein Interactions Michael A. Shogren‐Knaak, Haruhiko Ishii, Jian-Min Sun et al. · Science 9 Feb 2006 1,915
34 Gadd153 Sensitizes Cells to Endoplasmic Reticulum Stress by Down-Regulating Bcl2 and Perturbing the Cellular Redox State Karen D. McCullough, Jennifer L. Martindale, Lars‐Oliver Klotz et al. · Molecular and Cellular Biology Open access Feb 2001 1,908
35 Projections of Alzheimer's disease in the United States and the public health impact of delaying disease onset. Ron Brookmeyer, Steven G. Gray, Claudia H. Kawas · American Journal of Public Health Open access Sep 1998 1,814
36 Intimate Partner Violence as a Risk Factor for Mental Disorders: A Meta-Analysis Jacqueline M. Golding · Journal of Family Violence Review Jun 1999 1,803
37 Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes Rainer Malik et al. · Nature Genetics Open access428 authors 12 Mar 2018 1,753
38 Six new loci associated with body mass index highlight a neuronal influence on body weight regulation Cristen J. Willer et al. · Nature Genetics Open access145 authors 14 Dec 2008 1,733
39 Mitochondrial dysfunction and oxidative stress in metabolic disorders — A step towards mitochondria based therapeutic strategies Jasvinder Singh Bhatti, Gurjit Kaur Bhatti, P. Hemachandra Reddy · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease Open access 9 Nov 2016 1,694
40 Loss of Independence in Activities of Daily Living in Older Adults Hospitalized with Medical Illnesses: Increased Vulnerability with Age Kenneth E. Covinsky, Robert M. Palmer, Richard H. Fortinsky et al. · Journal of the American Geriatrics Society 26 Mar 2003 1,694
41 Exogenous α-Synuclein Fibrils Induce Lewy Body Pathology Leading to Synaptic Dysfunction and Neuron Death Laura A. Volpicelli‐Daley, Kelvin C. Luk, Tapan P. Patel et al. · Neuron Open access Oct 2011 1,649
42 NMDAR inhibition-independent antidepressant actions of ketamine metabolites Panos Zanos, Ruin Moaddel, Patrick J. Morris et al. · Nature Open access 3 May 2016 1,637
43 Research Agenda for Frailty in Older Adults: Toward a Better Understanding of Physiology and Etiology: Summary from the American Geriatrics Society/National Institute on Aging Research Conference on Frailty in Older Adults Jeremy D Walston, Evan C. Hadley, Luigi Ferrucci et al. · Journal of the American Geriatrics Society 4 May 2006 1,635
44 Sleep Complaints Among Elderly Persons: An Epidemiologic Study of Three Communities Daniel J. Foley, Andrew A. Monjan, Sandra L. Brown et al. · SLEEP Aug 1995 1,624
45 Effects of Intermittent Fasting on Health, Aging, and Disease Rafael de Cabo, Mark P. Mattson · New England Journal of Medicine 25 Dec 2019 1,615
46 Hearing Loss and Incident Dementia Frank Robert Lin, E. Jeffrey Metter, Richard O’Brien et al. · Archives of Neurology Open access Feb 2011 1,569
47 Primary age-related tauopathy (PART): a common pathology associated with human aging John F. Crary et al. · Acta Neuropathologica Open access 27 Oct 2014 1,541
48 Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALS Hong Joo Kim et al. · Nature Open access Mar 2013 1,535
49 Genome-wide association study identifies 74 loci associated with educational attainment Aysu Okbay et al. · Nature Open access256 authors 10 May 2016 1,500
50 Chronic Disease Self-Management Program Kate R. Lorig, Philip Lloyd Ritter, Anita L. Stewart et al. · Medical Care Nov 2001 1,496

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.