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Institution · Instituto de Biotecnología de León

Most cited papers from Instituto de Biotecnología de León

Instituto de Biotecnología de León

What are the most cited papers from Instituto de Biotecnología de León?

The most cited paper from Instituto de Biotecnología de León is "Insights into Land Plant Evolution Garnered from the Marchantia polymorpha Genome" (John L. Bowman et al., 2017), with 1,314 citations. Next come "Virulence factors of the Mycobacterium tuberculosis complex" (621) and "Genome sequencing and analysis of the filamentous fungus Penicillium chrysogenum" (478).

Showing 50 of 60 papers. Every paper with more than 103 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Insights into Land Plant Evolution Garnered from the Marchantia polymorpha Genome John L. Bowman et al. · Cell Open access113 authors Oct 2017 1,314
2 Virulence factors of the Mycobacterium tuberculosis complex Marina Andrea Forrellad, Laura Inés Klepp, Andrea Gioffré et al. · Virulence Open access 2013 621
3 Genome sequencing and analysis of the filamentous fungus Penicillium chrysogenum Marco A. van den Berg et al. · Nature Biotechnology Open access 28 Sep 2008 478
4 Nomenclature for HKT transporters, key determinants of plant salinity tolerance John Damien Platten et al. · Trends in Plant Science 5 Jul 2006 386
5 Melatonin‐induced increased activity of the respiratory chain complexes I and IV can prevent mitochondrial damage induced by ruthenium red in vivo Miguel Martı́n, M. Macías, Germaine Escames et al. · Journal of Pineal Research May 2000 299
6 Melatonin inhibits expression of the inducible NO synthase II in liver and lung and prevents endotoxemia in lipopolysaccharide‐induced multiple organ dysfunction syndrome in rats Elena Crespo, Manuel Jesús Macías, David Pozo et al. · The FASEB Journal Sep 1999 282
7 Sucrose signaling in plants: A world yet to be explored Pontis Horacio, Giselle M.A. Martínez-Noël · Plant Signaling & Behavior Open access 20 Feb 2013 256
8 The two-component PhoR-PhoP system controls both primary metabolism and secondary metabolite biosynthesis in Streptomyces lividans Alberto Sola‐Landa, Rute Silva Moura, Juan Francisco Martin · Proceedings of the National Academy of Sciences Open access 2 May 2003 245
9 The dynamic architecture of the metabolic switch in Streptomyces coelicolor Kay Nieselt et al. · BMC Genomics Open access 2010 210
10 Oestradiol potentiates the suppressive function of human CD4+ CD25+ regulatory T cells by promoting their proliferation G. Aleph Prieto, Yvonne Rosenstein · Immunology Open access 2 Mar 2006 207
11 DNA Vaccination Partially Protects against African Swine Fever Virus Lethal Challenge in the Absence of Antibodies Jordi M. Argilaguet, Eva Pérez-Martín, Miquel Nofrarías et al. · PLoS ONE Open access 26 Sep 2012 203
12 Melatonin is protective against MPTP-induced striatal and hippocampal lesions Darı́o Acuña-Castroviejo, Ana M. Coto‐Montes, Maria Gaia Monti et al. · Life Sciences Nov 1996 200
13 Auxins of microbial origin and their use in agriculture Chetan Keswani, Satyendra Pratap Singh, Laura Cueto et al. · Applied Microbiology and Biotechnology Open access 12 Sep 2020 187
14 Genetic diversity analysis of cultivated and wild grapevine (Vitis vinifera L.) accessions around the Mediterranean basin and Central Asia Summaira Riaz, Gabriella De Lorenzis, Dianne Velasco et al. · BMC Plant Biology Open access 27 Jun 2018 177
15 The global regulator LaeA controls penicillin biosynthesis, pigmentation and sporulation, but not roquefortine C synthesis in Penicillium chrysogenum Katarína Kosalková, Carlos García‐Estrada, Ricardo V. Ullán et al. · Biochimie 11 Oct 2008 174
16 Inhibition of neuronal nitric oxide synthase activity by N1‐acetyl‐5‐methoxykynuramine, a brain metabolite of melatonin Josefa León, Germaine Escames, María Isabel Rodríguez et al. · Journal of Neurochemistry 20 Jul 2006 158
17 Antibody-mediated neutralization of African swine fever virus: Myths and facts José M. Escribano, Inmaculada Galindo, Covadonga Alonso · Virus Research 14 Nov 2012 154
18 Diversity of the cultivable human gut microbiome involved in gluten metabolism: isolation of microorganisms with potential interest for coeliac disease Alberto Caminero, Alexandra R. Herrán, Esther Nistal et al. · FEMS Microbiology Ecology Open access 6 Feb 2014 154
19 High-performance capillary electrophoretic method for the quantification of 5-methyl 2'-deoxycytidine in genomic DNA: Application to plant, animal and human cancer tissues Mario Fernández Fraga, Esther Uriol, L. B. Diego et al. · Electrophoresis Jun 2002 153
20 The two-component phoR-phoP system of Streptomyces natalensis: Inactivation or deletion of phoP reduces the negative phosphate regulation of pimaricin biosynthesis Marta Vaz Mendes, Sedef Tunca, Nuria Antón et al. · Metabolic Engineering 25 Oct 2006 152
21 Programmed Cell Death Is Required for Palate Shelf Fusion and Is Regulated by Retinoic Acid Rodrigo Cuervo, Concepción Valencia, Roshantha A.S. Chandraratna et al. · Developmental Biology Open access May 2002 152
22 Attenuation of cardiac mitochondrial dysfunction by melatonin in septic mice Germaine Escames, Luis Carlos López, Francisco de Paula Ortiz et al. · FEBS Journal 20 Mar 2007 149
23 Proteome Analysis of the Penicillin Producer Penicillium chrysogenum Mohammad‐Saeid Jami, Carlos Barreiro, Carlos García‐Estrada et al. · Molecular & Cellular Proteomics Open access 13 Feb 2010 148
24 Polyene antibiotic biosynthesis gene clusters Jesús F. Aparicio, Patrick Caffrey, José A. Gil et al. · Applied Microbiology and Biotechnology 18 Dec 2002 148
25 Binding of PhoP to promoters of phosphate‐regulated genes in Streptomyces coelicolor: identification of PHO boxes Alberto Sola‐Landa, Antonio Rodríguez‐García, Etelvina Franco‐Domínguez et al. · Molecular Microbiology Open access 30 Mar 2005 148
26 A complex multienzyme system encoded by five polyketide synthase genes is involved in the biosynthesis of the 26-membered polyene macrolide pimaricin in Streptomyces natalensis Jesús F. Aparicio, Roberto Fouces, Marta Vaz Mendes et al. · Chemistry & Biology Open access Nov 2000 146
27 Current status on prevention and treatment of canine leishmaniasis Rosa Maria Reguera, Miguel Ángel Olego Morán, Yolanda Pérez‐Pertejo et al. · Veterinary Parasitology 15 Jul 2016 144
28 Antimicrobial secondary metabolites from agriculturally important bacteria as next-generation pesticides Chetan Keswani, Harikesh Bahadur Singh, Carlos García‐Estrada et al. · Applied Microbiology and Biotechnology 19 Dec 2019 143
29 Snakin/GASA proteins Vanesa Nahirñak, Natalia Inés Almasia, H. Esteban Hopp et al. · Plant Signaling & Behavior Open access Aug 2012 139
30 Biosynthesis of Astaxanthin as a Main Carotenoid in the Heterobasidiomycetous Yeast Xanthophyllomyces dendrorhous José Luis Barredo, Carlos García‐Estrada, Katarína Kosalková et al. · Journal of Fungi Open access 30 Jul 2017 136
31 PimM, a PAS domain positive regulator of pimaricin biosynthesis in Streptomyces natalensis Nuria Antón, Javier Santos‐Aberturas, Marta Vaz Mendes et al. · Microbiology Sep 2007 136
32 Structure-Related Inhibition of Calmodulin-Dependent Neuronal Nitric-Oxide Synthase Activity by Melatonin and Synthetic Kynurenines Josefa León, Manuel Jesús Macías, Germaine Escames et al. · Molecular Pharmacology Nov 2000 133
33 New sources and antifungal activity of sesquiterpene lactones Alejandro F. Barrero, Juan Enrique Oltra, Miriam Alvarez‐Corral et al. · Fitoterapia Feb 2000 133
34 Identification of volatile compounds produced by the bacteriumBurkholderia tropicathat inhibit the growth of fungal pathogens Silvia Tenorio‐Salgado, Raunel Tinoco, Rafael Vázquez-Duhalt et al. · Bioengineered Open access 16 May 2013 132
35 Molecular genetics of naringenin biosynthesis, a typical plant secondary metabolite produced by Streptomyces clavuligerus Rubén Álvarez-Álvarez, Alma Botas, Silvia María Albillos et al. · Microbial Cell Factories Open access 9 Nov 2015 129
36 Phosphate control over nitrogen metabolism in Streptomyces coelicolor: direct and indirect negative control of glnR, glnA, glnII and amtB expression by the response regulator PhoP Antonio Rodríguez‐García, Alberto Sola‐Landa, Kristian Apel et al. · Nucleic Acids Research Open access 24 Mar 2009 127
37 Antigenic and immunogenic properties of a chimera of two immunodominant African swine fever virus proteins María G. Barderas, Fernando A. Rodriguez, Paulino Gómez‐Puertas et al. · Archives of Virology Open access Sep 2001 126
38 Identification of PimR as a Positive Regulator of Pimaricin Biosynthesis in Streptomyces natalensis Nuria Antón, Marta Vaz Mendes, Juan Francisco Martin et al. · Journal of Bacteriology Open access 16 Apr 2004 125
39 Cross‐talk between two global regulators in Streptomyces: PhoP and AfsR interact in the control of afsS, pstS and phoRP transcription Fernando Santos‐Beneit, Antonio Rodríguez‐García, Alberto Sola‐Landa et al. · Molecular Microbiology Open access 11 Feb 2009 125
40 Expression and antiviral activity of a β-defensin-like peptide identified in the rainbow trout (Oncorhynchus mykiss) EST sequences Alberto Falcó, Verónica Chico, Laura Marroquí et al. · Molecular Immunology 10 Aug 2007 124
41 Genome‐wide transcriptomic and proteomic analysis of the primary response to phosphate limitation in Streptomyces coelicolor M145 and in a ΔphoP mutant Antonio Rodríguez‐García, Carlos Barreiro, Fernando Santos‐Beneit et al. · PROTEOMICS Open access Jul 2007 124
42 African swine fever virus serodiagnosis: A general review with a focus on the analyses of African serum samples Carolina Cubillos‐Zapata, Silvia Gómez-Sebastián, Noelia Moreno et al. · Virus Research 3 Nov 2012 122
43 ST-246 is a key antiviral to inhibit the viral F13L phospholipase, one of the essential proteins for orthopoxvirus wrapping Sophie Duraffour, Marı́a M. Lorenzo, Gudrun Zöller et al. · Journal of Antimicrobial Chemotherapy Open access 27 Jan 2015 120
44 Phosphate control of phoA, phoC and phoD gene expression in Streptomyces coelicolor reveals significant differences in binding of PhoP to their promoter regions Alexander Kristian Apel, Alberto Sola‐Landa, Antonio Rodríguez‐García et al. · Microbiology Open access 28 Sep 2007 118
45 Surface analysis of Dicrocoelium dendriticum. The molecular characterization of exosomes reveals the presence of miRNAs Dolores Lopez Bernal, María Trelis, Sergio Montaner-Tarbés et al. · Journal of Proteomics 20 Feb 2014 118
46 NRPSsp: non-ribosomal peptide synthase substrate predictor Carlos Alberto Vanegas Prieto, Carlos García‐Estrada, Diego Lorenzana et al. · Bioinformatics Open access 29 Nov 2011 116
47 A Single Cluster of Coregulated Genes Encodes the Biosynthesis of the Mycotoxins Roquefortine C and Meleagrin in Penicillium chrysogenum Carlos García‐Estrada, Ricardo V. Ullán, Silvia María Albillos et al. · Chemistry & Biology Open access Nov 2011 115
48 Methods for the nanoencapsulation of β-carotene in the food sector Francisco Gutiérrez‐Agüera, Silvia María Albillos, Elvira Casas-Sanz et al. · Trends in Food Science & Technology Open access 31 May 2013 114
49 BacMam immunization partially protects pigs against sublethal challenge with African swine fever virus Jordi M. Argilaguet, Eva Pérez-Martín, Sergio Luis González López et al. · Antiviral Research Open access 19 Feb 2013 113
50 Dietary supplemental plant oils reduce methanogenesis from anaerobic microbial fermentation in the rumen J. E. Vargas, Sonia Andrés, Lorena López‐Ferreras et al. · Scientific Reports Open access 31 Jan 2020 110

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.