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Institution · Instituto de Salud Carlos III

Most cited papers from Instituto de Salud Carlos III

Instituto de Salud Carlos III

What are the most cited papers from Instituto de Salud Carlos III?

The most cited paper from Instituto de Salud Carlos III is "Sorafenib in Advanced Hepatocellular Carcinoma" (Josep Maria Llovet et al., 2008), with 13,116 citations. Next come "Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines" (11,535) and "The mutational constraint spectrum quantified from variation in 141,456 humans" (10,422).

Showing 50 of 59 papers. Every paper with more than 2,336 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Sorafenib in Advanced Hepatocellular Carcinoma Josep Maria Llovet et al. · New England Journal of Medicine Open access 23 Jul 2008 13,116
2 Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines Clotilde Théry et al. · Journal of Extracellular Vesicles Open access382 authors 23 Nov 2018 11,535
3 The mutational constraint spectrum quantified from variation in 141,456 humans Konrad J. Karczewski et al. · Nature Open access177 authors 27 May 2020 10,422
4 Development and preliminary testing of the new five-level version of EQ-5D (EQ-5D-5L) Michael Herdman, Claire M. Gudex, Andrew J. Lloyd et al. · Quality of Life Research Open access 8 Apr 2011 10,323
5 Movement Disorder Society‐sponsored revision of the Unified Parkinson's Disease Rating Scale (MDS‐UPDRS): Scale presentation and clinimetric testing results Christopher G. Goetz et al. · Movement Disorders Open access 15 Nov 2008 7,783
6 Global, Regional, and National Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life-years for 32 Cancer Groups, 1990 to 2015 Christina Fitzmaurice et al. · JAMA Oncology Open access185 authors 5 Dec 2016 6,333
7 Neuroinflammation in Alzheimer's disease Michael Thomas Heneka et al. · The Lancet Neurology Open access 16 Mar 2015 6,318
8 Infectious Diseases Society of America/American Thoracic Society Consensus Guidelines on the Management of Community-Acquired Pneumonia in Adults Lionel A. Mandell, Richard G. Wunderink, Antonio Anzueto et al. · Clinical Infectious Diseases Open access 3 Feb 2007 6,286
9 Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) Daniel J. Klionsky et al. · Autophagy Open access2,467 authors 2 Jan 2016 6,023
10 Epidemiology, Patterns of Care, and Mortality for Patients With Acute Respiratory Distress Syndrome in Intensive Care Units in 50 Countries Giacomo Bellani, John Gerard Laffey, Tài Pham et al. · JAMA Open access 22 Feb 2016 6,014
11 Planck 2015 results Ade, PAR et al. · ORCA Online Research @Cardiff (Cardiff University) Open access261 authors Oct 2016 5,452
12 Leishmaniasis Worldwide and Global Estimates of Its Incidence Jorge Alvar, Iván Darío Vélez, Caryn Bern et al. · PLoS ONE Open access 31 May 2012 5,260
13 Review of Particle Physics C. Amsler et al. · Physics Letters B Open access173 authors 5 Aug 2008 5,093
14 The IASLC Lung Cancer Staging Project: Proposals for Revision of the TNM Stage Groupings in the Forthcoming (Eighth) Edition of the TNM Classification for Lung Cancer Peter Goldstraw et al. · Journal of Thoracic Oncology Open access152 authors 2016 4,749
15 Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease European Alzheimer's Disease Initiative (EADI) et al. · Nature Genetics ReviewOpen access184 authors 27 Oct 2013 4,711
16 The COSMIN study reached international consensus on taxonomy, terminology, and definitions of measurement properties for health-related patient-reported outcomes Lidwine Brigitta Mokkink, Caroline Barbara Terwee, Donald L. Patrick et al. · Journal of Clinical Epidemiology Open access 22 May 2010 4,581
17 Nivolumab in patients with advanced hepatocellular carcinoma (CheckMate 040): an open-label, non-comparative, phase 1/2 dose escalation and expansion trial Anthony B. El-Khoueiry et al. · The Lancet Open access 20 Apr 2017 4,384
18 The COSMIN checklist for assessing the methodological quality of studies on measurement properties of health status measurement instruments: an international Delphi study Lidwine Brigitta Mokkink, Caroline Barbara Terwee, Donald L. Patrick et al. · Quality of Life Research Open access 18 Feb 2010 4,362
19 Estimates of incidence and mortality of cervical cancer in 2018: a worldwide analysis Marc Arbyn, Elisabete Weiderpass, Laia Bruni et al. · The Lancet Global Health Open access 4 Dec 2019 4,260
20 Global, Regional, and National Burden of Cardiovascular Diseases for 10 Causes, 1990 to 2015 Gregory A. Roth et al. · Journal of the American College of Cardiology Open access171 authors 17 May 2017 3,906
21 Age at onset of mental disorders worldwide: large-scale meta-analysis of 192 epidemiological studies Marco Solmi, Joaquim Raduà, Miriam Olivola et al. · Molecular Psychiatry ReviewOpen access 2 Jun 2021 3,868
22 The repertoire of mutational signatures in human cancer Ludmil B. Alexandrov et al. · Nature Open access1,384 authors 5 Feb 2020 3,854
23 Five-Year Survival with Combined Nivolumab and Ipilimumab in Advanced Melanoma James Larkin et al. · New England Journal of Medicine Open access 28 Sep 2019 3,784
24 Epigenetic differences arise during the lifetime of monozygotic twins Mario Fernández Fraga et al. · Proceedings of the National Academy of Sciences Open access 11 Jul 2005 3,643
25 Primary Prevention of Cardiovascular Disease with a Mediterranean Diet Supplemented with Extra-Virgin Olive Oil or Nuts Ramón Estruch et al. · New England Journal of Medicine Open access 13 Jun 2018 3,630
26 COSMIN guideline for systematic reviews of patient-reported outcome measures C.A.C. Prinsen, Lidwine Brigitta Mokkink, L.M. Bouter et al. · Quality of Life Research ReviewOpen access 12 Feb 2018 3,453
27 The tomato genome sequence provides insights into fleshy fruit evolution Hideki Hirakawa et al. · Nature Open access271 authors May 2012 3,442
28 2023 ESH Guidelines for the management of arterial hypertension The Task Force for the management of arterial hypertension of the European Society of Hypertension Giuseppe Mancia et al. · Journal of Hypertension Open access 24 Jun 2023 3,385
29 Pan-cancer analysis of whole genomes Lauri A. Aaltonen et al. · Nature Open access1,324 authors 5 Feb 2020 3,360
30 Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease 2017 Report. GOLD Executive Summary Claus Franz Vogelmeier et al. · American Journal of Respiratory and Critical Care Medicine Open access Mar 2017 3,296
31 Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing Brian W. Kunkle et al. · Nature Genetics ReviewOpen access469 authors 28 Feb 2019 3,277
32 International Classification of Functioning, Disability and Health (ICF) 2001 María Teresa Jiménez-Buñuales, Paulino González Diego, José Manuel Almansa Moreno · Revista Española de Salud Pública Open access Aug 2002 3,272
33 Review of Particle Properties K. Hagiwara et al. · Physical review. D. Particles, fields, gravitation, and cosmology/Physical review. D. Particles and fields 140 authors Jul 2002 3,120
34 Susceptibility to Exacerbation in Chronic Obstructive Pulmonary Disease John Robert Hurst, Jørgen Vestbo, Antonio R. Anzueto et al. · New England Journal of Medicine Open access 15 Sep 2010 3,024
35 Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index MAGIC et al. · Nature Genetics Open access376 authors 10 Oct 2010 2,999
36 Synaptic, transcriptional and chromatin genes disrupted in autism The DDD Study et al. · Nature Open access 29 Oct 2014 2,993
37 Revision and Update of the Consensus Definitions of Invasive Fungal Disease From the European Organization for Research and Treatment of Cancer and the Mycoses Study Group Education and Research Consortium J. Peter Donnelly et al. · Clinical Infectious Diseases Open access 8 Oct 2019 2,973
38 COVID-19 and Thrombotic or Thromboembolic Disease: Implications for Prevention, Antithrombotic Therapy, and Follow-Up Behnood Bikdeli et al. · Journal of the American College of Cardiology Open access 17 Apr 2020 2,956
39 Mapping genomic loci implicates genes and synaptic biology in schizophrenia Vassily Vladimirovich Trubetskoy et al. · Nature Open access613 authors 8 Apr 2022 2,894
40 GRADE guidelines: 4. Rating the quality of evidence—study limitations (risk of bias) Gordon Henry Guyatt, Andrew David Oxman, Gunn Elisabeth Vist et al. · Journal of Clinical Epidemiology 24 Jan 2011 2,894
41 Human papillomavirus genotype attribution in invasive cervical cancer: a retrospective cross-sectional worldwide study Silvia de Sanjosé et al. · The Lancet Oncology 18 Oct 2010 2,774
42 GRADE guidelines 6. Rating the quality of evidence—imprecision Gordon Henry Guyatt, Andrew David Oxman, Regina Kunz et al. · Journal of Clinical Epidemiology 15 Aug 2011 2,755
43 Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 1 Daniel J. Klionsky et al. · Autophagy Open access2,930 authors 2 Jan 2021 2,743
44 Global, Regional, and National Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life-Years for 29 Cancer Groups, 1990 to 2017 Christina Fitzmaurice et al. · JAMA Oncology Open access628 authors 27 Sep 2019 2,699
45 A clinical case definition of post-COVID-19 condition by a Delphi consensus Joan B Soriano, Srinivas Murthy, John C Marshall et al. · The Lancet Infectious Diseases Open access 21 Dec 2021 2,676
46 New insights into the genetic etiology of Alzheimer’s disease and related dementias Céline Bellenguez et al. · Nature Genetics Open access1,266 authors Apr 2022 2,608
47 Exploring pathways linking greenspace to health: Theoretical and methodological guidance Iana Markevych, Julia Schoierer, Terry Hartig et al. · Environmental Research Open access 30 Jun 2017 2,550
48 Cholangiocarcinoma 2020: the next horizon in mechanisms and management Jesús M. Bañales et al. · Nature Reviews Gastroenterology & Hepatology ReviewOpen access 30 Jun 2020 2,543
49 Childhood adversities and adult psychopathology in the WHO World Mental Health Surveys Ronald C. Kessler et al. · The British Journal of Psychiatry Open access 29 Oct 2010 2,532
50 Physical illness in patients with severe mental disorders. I. Prevalence, impact of medications and disparities in health care MARC DE HERT, Christoph Ulrich Correll, Julio Bobes et al. · World Psychiatry Open access Feb 2011 2,531

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.