Institution · Instituto Nacional de la Salud
Most cited papers from Instituto Nacional de la Salud
What are the most cited papers from Instituto Nacional de la Salud?
The most cited paper from Instituto Nacional de la Salud is "Interleukin‐6 is the major regulator of acute phase protein synthesis in adult human hepatocytes" (José Vicente Castell, Marı́a José Gómez-Lechón, Martina David et al., 1989), with 911 citations. Next come "Sorting it out: Regulation of exosome loading" (762) and "Emergence of Azole Resistance in Aspergillus fumigatus and Spread of a Single Resistance Mechanism" (734).
Showing 50 of 60 papers. Every paper with more than 78 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Interleukin‐6 is the major regulator of acute phase protein synthesis in adult human hepatocytes José Vicente Castell, Marı́a José Gómez-Lechón, Martina David et al. · FEBS Letters | 2 Jan 1989 | 911 |
| 2 | Sorting it out: Regulation of exosome loading Carolina Villarroya‐Beltri, Francesc Baixauli, Cristina Gutiérrez‐Vázquez et al. · Seminars in Cancer Biology | 23 Apr 2014 | 762 |
| 3 | Emergence of Azole Resistance in Aspergillus fumigatus and Spread of a Single Resistance Mechanism Eveline Snelders, Henrich A. L. van der Lee, Judith Kuijpers et al. · PLoS Medicine | 7 Nov 2008 | 734 |
| 4 | Recombinant human interleukin‐6 (IL‐6/BSF‐2/HSF) regulates the synthesis of acute phase proteins in human hepatocytes José Vicente Castell, Marı́a José Gómez-Lechón, Martina David et al. · FEBS Letters | 23 May 1988 | 458 |
| 5 | Viruses causing gastroenteritis Isabel Wilhelmi, Enriqueta Román, Alicia Sánchez-Fauquier · Clinical Microbiology and Infection | Apr 2003 | 400 |
| 6 | Blockade of the Bcr-Abl Kinase Activity Induces Apoptosis of Chronic Myelogenous Leukemia Cells by Suppressing Signal Transducer and Activator of Transcription 5–Dependent Expression of Bcl-XL Machiko Horita, Enrique José Andreu, Adalberto Benito et al. · The Journal of Experimental Medicine | 13 Mar 2000 | 369 |
| 7 | New evidence of risk factors for community-acquired pneumonia: a population-based study J. Almirall, Ignasi Bolíbar, Mateu Serra‐Prat et al. · European Respiratory Journal | 23 Jan 2008 | 363 |
| 8 | Erythropoietin Can Induce the Expression of Bcl-xLthrough Stat5 in Erythropoietin-dependent Progenitor Cell Lines Maite Silva, Adalberto Benito, Cristina Sanz et al. · Journal of Biological Chemistry | Aug 1999 | 280 |
| 9 | New procedure for the treatment of colorectal neoplastic obstructions Eloy Tejero, Antonio Sicras Mainar, L. Fernández et al. · Diseases of the Colon & Rectum | Nov 1994 | 268 |
| 10 | Antibiotic‐Selective Environments Fernando Baquero, Marı́a-Cristina Negri, Marı́a-Isabel Morosini et al. · Clinical Infectious Diseases | Aug 1998 | 244 |
| 11 | Host cell heparan sulfate proteoglycans mediate attachment and entry of Listeria monocytogenes, and the listerial surface protein ActA is involved in heparan sulfate receptor recognition Carmen Alvarez-Domı́nguez, J A Vázquez-Boland, Eugenio Carrasco-Marı́n et al. · Infection and Immunity | 1997 | 212 |
| 12 | Antioxidant response to oxidative stress induced by exhaustive exercise Antoni Aguiló, Pedro Tauler, Emilia Fuentespina et al. · Physiology & Behavior | 12 Nov 2004 | 209 |
| 13 | Lipid Peroxidation and Antioxidant Enzyme Activities in Vascular and Alzheimer Dementias Ángela Casado, Ma Encarnación López-Fernández, Ma Concepción Casado et al. · Neurochemical Research | 24 Aug 2007 | 206 |
| 14 | A review of antibiotic resistance patterns of Streptococcus pneumoniae in Europe Fernando Baquero, J. M. Beltren, Elena Martínez Loza · Journal of Antimicrobial Chemotherapy | 1991 | 201 |
| 15 | Los grupos de morbilidad ajustados: nuevo agrupador de morbilidad poblacional de utilidad en el ámbito de la atención primaria David Monterde, Emili Vela, Montse Clèries · Atención Primaria | 4 Aug 2016 | 200 |
| 16 | Low-level antibacterial resistance: a gateway to clinical resistance Fernando Baquero · Drug Resistance Updates | Apr 2001 | 200 |
| 17 | Acute Colorectal Obstruction: Treatment with Self-expandable Metallic Stents before Scheduled Surgery—Results of a Multicenter Study Antonio Sicras Mainar, Miguel Angel De Gregorio Ariza, Eloy Tejero et al. · Radiology | 1999 | 199 |
| 18 | Familial dilated cardiomyopathy and isolated left ventricular noncompaction associated with lamin A/C gene mutations Manuel Hermida‐Prieto, Lorenzo Monserrat, Alfonso Castro‐Beiras et al. · The American Journal of Cardiology | 24 Jun 2004 | 189 |
| 19 | Sequence divergence of measles virus haemagglutinin during natural evolution and adaptation to cell culture. BERT K. RIMA, R Fernandez-Mu√±oz, María Luisa Celma et al. · Journal of General Virology | 1997 | 177 |
| 20 | Interleukin-6 is the Major Regulator of Acute Phase Protein Synthesis in Rat and Man José Vicente Castell, Michael David, Jan‐Michael Axel Klapproth et al. · Elsevier eBooks | 1989 | 177 |
| 21 | Clinical and Molecular Analysis of Five(Inv) Dup(15) Patients Wendy P. Robinson, Franz Binkert, Ramon Giné et al. · European Journal of Human Genetics | 1993 | 174 |
| 22 | The microcins Fernando Baquero, Felipe Moreno · FEMS Microbiology Letters | Jul 1984 | 172 |
| 23 | Aspectos epidemiológicos del síndrome de Burnout en personal sanitario Juan Carlos Atance Martínez · Revista Española de Salud Pública | May 1997 | 169 |
| 24 | The Immunohistochemical Diagnostic Panel for Epithelial Mesothelioma Jose R. Riera, Carlos Astengo-Osuna, Jeff Longmate et al. · The American Journal of Surgical Pathology | Dec 1997 | 167 |
| 25 | Proxy‐reported health‐related quality of life of patients with juvenile idiopathic arthritis: The pediatric rheumatology international trials organization multinational quality of life cohort study Sheila Oliveira et al. · Arthritis Care & Research | 31 Jan 2007 | 165 |
| 26 | Pneumococcal Resistance to β-Lactam Antibiotics: A Global Geographic Overview Fernando Baquero · Microbial Drug Resistance | Jun 1995 | 158 |
| 27 | Nutritional Factors and Gastric Cancer in Spain Carlos A. Gonz ́lez, Elio Ríboli, J Badosa et al. · American Journal of Epidemiology | Mar 1994 | 147 |
| 28 | Relation between oxidative stress markers and antioxidant endogenous defences during exhaustive exercise Antoni Sureda, Pedro Tauler, Antoni Aguiló et al. · Free Radical Research | 2005 | 146 |
| 29 | MicroRNA dysregulation in spinal cord injury: causes, consequences and therapeutics Manuel Nieto‐Díaz, Francisco José Esteban, David Reigada et al. · Frontiers in Cellular Neuroscience | 2014 | 144 |
| 30 | Structure-Based Enhancement of Boronic Acid-Based Inhibitors of AmpC β-Lactamase G. Scott Weston, Jesús Blázquez, Fernando Baquero et al. · Journal of Medicinal Chemistry | 13 Oct 1998 | 143 |
| 31 | Evolution of antibiotic resistance Fernando Baquero, Jesús Blázquez · Trends in Ecology & Evolution | Dec 1997 | 141 |
| 32 | Neonatal Hypothyroxinemia: Effects of Iodine Intake and Premature Birth1 Susana Ares Segura, Héctor Francisco Escobar-Morreale, José Quero et al. · The Journal of Clinical Endocrinology & Metabolism | Jun 1997 | 133 |
| 33 | Clinical Isolates of Measles Virus Use CD46 as a Cellular Receptor Marianne Manchester, Danelle S. Eto, Alexandra Valsamakis et al. · Journal of Virology | May 2000 | 132 |
| 34 | Concentration-Dependent Selection of Small Phenotypic Differences in TEM β-Lactamase-Mediated Antibiotic Resistance Marı́a-Cristina Negri, Marc Lipsitch, Jesús Blázquez et al. · Antimicrobial Agents and Chemotherapy | Sep 2000 | 128 |
| 35 | Presence of Human Herpesvirus-8 DNA Sequences and Overexpression of Human IL-6 and Cyclin D1 in Inflammatory Myofibroblastic Tumor (Inflammatory Pseudotumor) José Javier Gómez-Román, Gonzalo Ocejo-Vinyals, Pablo Sánchez‐Velasco et al. · Laboratory Investigation | Jul 2000 | 128 |
| 36 | Trends in antibiotic resistance of respiratory pathogens: an analysis and commentary on a collaborative surveillance study Fernando Baquero · Journal of Antimicrobial Chemotherapy | Jul 1996 | 127 |
| 37 | Colorectal obstruction: treatment with metallic stents. Ana M. Mainar, Emilio José Emmanuel Tejero, Manuel Maynar et al. · Radiology | Mar 1996 | 125 |
| 38 | Challenges: Selective compartments for resistant microorganisms in antibiotic gradients Fernando Baquero, Marı́a-Cristina Negri · BioEssays | Aug 1997 | 124 |
| 39 | The risk of cardiovascular disease associated with proteinuria in renal transplant patients Gema Fern ndez-Fresnedo, Rafael Escallada, Emilio Rodrigo et al. · Transplantation | Apr 2002 | 121 |
| 40 | Musculoskeletal Pain in Primary Pediatric Care: Analysis of 1000 Consecutive General Pediatric Clinic Visits Jaime de Inocencio Arocena · PEDIATRICS | Dec 1998 | 119 |
| 41 | CHEMICAL CORRELATES OF PATHOGENICITY OF OILS RELATED TO THE TOXIC OIL SYNDROME EPIDEMIC IN SPAIN Edwin M. Kilbourne, John T. Bernert, Manuel Posada de la Paz et al. · American Journal of Epidemiology | Jun 1988 | 118 |
| 42 | Chronic Bile Duct Ligation in the Dog: Hemodynamic Characterization of a Portal Hypertensive Model Jaime Bosch, Rosa E. Enriquez, Roberto J. Groszmann et al. · Hepatology | Nov 1983 | 114 |
| 43 | Correlation between transcranial interleukin-6 gradient and outcome in patients with acute brain injury Eduardo Miñambres, Arantxa Cemborain, Pablo Sánchez‐Velasco et al. · Critical Care Medicine | Mar 2003 | 106 |
| 44 | Transiciones de cuidados entre insuficiencia cardiaca aguda y crónica: pasos críticos en el diseño de un modelo de atención multidisciplinaria para la prevención de la hospitalización recurrente Josep Comín‐Colet, Cristina Enjuanes, Josep Lupón et al. · Revista Española de Cardiología | 6 Jun 2016 | 104 |
| 45 | Dietary factors and stomach cancer in Spain: A multi‐centre case‐control study Carlos Alberto Gonzalez, José Miguel Cuevas Sanz, Guillermo Marcos et al. · International Journal of Cancer | 21 Oct 1991 | 102 |
| 46 | Influence of vitamin C diet supplementation on endogenous antioxidant defences during exhaustive exercise Pedro Tauler, Antoni Aguiló, Isabel M. Gimeno et al. · Pflügers Archiv - European Journal of Physiology | 12 Jul 2003 | 98 |
| 47 | Comparison of three different regimens in the treatment of acute brucellosis: a multicenter multinational study Giovani Acocella, André Bertrand, Jean Beytout et al. · Journal of Antimicrobial Chemotherapy | 1989 | 98 |
| 48 | Culture of human hepatocytes from small surgical liver biopsies. Biochemical characterization and comparison with in vivo M.J. Gómez-Lechón, Pílar López, María Teresa Donato et al. · In Vitro Cellular & Developmental Biology - Plant | 1990 | 97 |
| 49 | Ivermectin as a novel complementary malaria control tool to reduce incidence and prevalence: a modelling study Hannah Slater, Brian D. Foy, Kevin C. Kobylinski et al. · The Lancet Infectious Diseases | 13 Jan 2020 | 94 |
| 50 | In vitro selective antibiotic concentrations of beta-lactams for penicillin-resistant Streptococcus pneumoniae populations M. C. Negri, M.I. Morosini, Elena Martínez Loza et al. · Antimicrobial Agents and Chemotherapy | 1994 | 94 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.