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Most cited papers from Isala

What are the most cited papers from Isala?

The most cited paper from Isala is "A Randomized Trial of Intraarterial Treatment for Acute Ischemic Stroke" (Olvert A. Berkhemer et al., 2014), with 6,707 citations. Next come "Early Rhythm-Control Therapy in Patients with Atrial Fibrillation" (2,193) and "Cryoballoon or Radiofrequency Ablation for Paroxysmal Atrial Fibrillation" (1,960).

Showing 50 of 60 papers. Every paper with more than 423 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 A Randomized Trial of Intraarterial Treatment for Acute Ischemic Stroke Olvert A. Berkhemer et al. · New England Journal of Medicine Open access 17 Dec 2014 6,707
2 Early Rhythm-Control Therapy in Patients with Atrial Fibrillation Paulus F. Kirchhof et al. · New England Journal of Medicine Open access 29 Aug 2020 2,193
3 Cryoballoon or Radiofrequency Ablation for Paroxysmal Atrial Fibrillation Karl-Heinz Kuck, Josép Brugada, Alexander Fürnkranz et al. · New England Journal of Medicine Open access 4 Apr 2016 1,960
4 Use of clopidogrel with or without aspirin in patients taking oral anticoagulant therapy and undergoing percutaneous coronary intervention: an open-label, randomised, controlled trial Willem J.M. Dewilde, Tom Oirbans, Freek W.A. Verheugt et al. · The Lancet 12 Feb 2013 1,725
5 Time Delay to Treatment and Mortality in Primary Angioplasty for Acute Myocardial Infarction Giuseppe De Luca, Harry Suryapranata, Jan Paul Ottervanger et al. · Circulation 9 Mar 2004 1,557
6 Percutaneous Coronary Intervention of Functionally Nonsignificant Stenosis Nico H.J. Pijls, Pepijn van Schaardenburgh, Ganesh Manoharan et al. · Journal of the American College of Cardiology Open access May 2007 1,515
7 Effects of Robot-Assisted Therapy on Upper Limb Recovery After Stroke: A Systematic Review Gert Kwakkel, Boudewijn J. Kollen, Hermano Igo Krebs · Neurorehabilitation and neural repair ReviewOpen access 17 Sep 2007 1,512
8 Associations of kidney disease measures with mortality and end-stage renal disease in individuals with and without diabetes: a meta-analysis Caroline S. Fox, Kunihiro Matsushita, Mark Woodward et al. · The Lancet ReviewOpen access 23 Sep 2012 1,413
9 Preoperative Chemoradiotherapy Versus Immediate Surgery for Resectable and Borderline Resectable Pancreatic Cancer: Results of the Dutch Randomized Phase III PREOPANC Trial Eva Versteijne et al. · Journal of Clinical Oncology Open access 27 Feb 2020 1,101
10 Encorafenib plus binimetinib versus vemurafenib or encorafenib in patients with BRAF-mutant melanoma (COLUMBUS): a multicentre, open-label, randomised phase 3 trial Reinhard Dummer, Paolo A. Ascierto, Helen J Gogas et al. · The Lancet Oncology Open access 21 Mar 2018 1,040
11 Gender differences in coronary heart disease Angela H.E.M. Maas, Yolande Appelman · Netherlands Heart Journal Open access Nov 2010 996
12 Estimated glomerular filtration rate and albuminuria for prediction of cardiovascular outcomes: a collaborative meta-analysis of individual participant data Kunihiro Matsushita et al. · The Lancet Diabetes & Endocrinology ReviewOpen access 29 May 2015 920
13 Fractional Flow Reserve to Determine the Appropriateness of Angioplasty in Moderate Coronary Stenosis G. Jan Willem Bech, Bernard De Bruyne, Nico H.J. Pijls et al. · Circulation Open access 19 Jun 2001 915
14 ERS guidelines on the diagnosis and treatment of chronic cough in adults and children Alyn H. Morice, Eva Millqvist, Kristina Biekšienė et al. · European Respiratory Journal Open access 12 Sep 2019 907
15 Five-Year Outcomes with PCI Guided by Fractional Flow Reserve Panagiotis Xaplanteris et al. · New England Journal of Medicine Open access 22 May 2018 872
16 Definition, assessment and treatment of wheezing disorders in preschool children: an evidence-based approach Paul L.P. Brand et al. · European Respiratory Journal Open access 30 Sep 2008 868
17 Efficacy and safety of procalcitonin guidance in reducing the duration of antibiotic treatment in critically ill patients: a randomised, controlled, open-label trial Evelien de Jong et al. · The Lancet Infectious Diseases Open access 2 Mar 2016 847
18 High-Dose Daunorubicin in Older Patients with Acute Myeloid Leukemia Bob Löwenberg, Gert Jan Ossenkoppele, Wim van Putten et al. · New England Journal of Medicine Open access 23 Sep 2009 833
19 Molecular Minimal Residual Disease in Acute Myeloid Leukemia Mojca Jongen‐Lavrencic et al. · New England Journal of Medicine Open access 28 Mar 2018 801
20 Single-agent bevacizumab or lomustine versus a combination of bevacizumab plus lomustine in patients with recurrent glioblastoma (BELOB trial): a randomised controlled phase 2 trial Walter Taal et al. · The Lancet Oncology 14 Jul 2014 768
21 Neoadjuvant Chemoradiotherapy Versus Upfront Surgery for Resectable and Borderline Resectable Pancreatic Cancer: Long-Term Results of the Dutch Randomized PREOPANC Trial Eva Versteijne et al. · Journal of Clinical Oncology Open access 27 Jan 2022 755
22 Endoscopic or Surgical Step-Up Approach for Infected Necrotising Pancreatitis: A Multicentre Randomised Trial Sandra van Brunschot et al. · The Lancet Open access 3 Nov 2017 743
23 Population-based epidemiology, malignancy risk, and outcome of primary sclerosing cholangitis Kirsten Boonstra, Rinse Karel Weersma, Karel J. van Erpecum et al. · Hepatology Open access 14 Jun 2013 732
24 Understanding the pattern of functional recovery after stroke: Facts and theories Gert Kwakkel, Boudewijn J. Kollen, Eline Lindeman · Restorative Neurology and Neuroscience 2004 729
25 Predictors of Coronary Stent Thrombosis Jochem Wouter van Werkum, Antonius A.C.M. Heestermans, Anoek Zomer et al. · Journal of the American College of Cardiology Open access Apr 2009 700
26 IFCC Reference System for Measurement of Hemoglobin A1c in Human Blood and the National Standardization Schemes in the United States, Japan, and Sweden: A Method-Comparison Study Wieland Hoelzel, Cas W. Weykamp, Jan‐Olof Jeppsson et al. · Clinical Chemistry 2004 698
27 Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome Database Mev Dominguez–Valentin et al. · Genetics in Medicine Open access 23 Jul 2019 679
28 Prehospital Ticagrelor in ST-Segment Elevation Myocardial Infarction Gilles Montalescot et al. · New England Journal of Medicine Open access Sep 2014 663
29 A Genotype-Guided Strategy for Oral P2Y 12 Inhibitors in Primary PCI Daniel M.F. Claassens, Gerrit J.A. Vos, Thomas O. Bergmeijer et al. · New England Journal of Medicine Open access 3 Sep 2019 649
30 Sequential versus combination chemotherapy with capecitabine, irinotecan, and oxaliplatin in advanced colorectal cancer (CAIRO): a phase III randomised controlled trial Miriam Koopman, Ninja F. Antonini, Joep Douma et al. · The Lancet Jul 2007 633
31 Incidence and clinical significance of distal embolization during primary angioplasty for acute myocardial infarction Jorge M. O. Henriques · European Heart Journal 15 Jul 2002 632
32 Minimally Invasive Versus Open Distal Pancreatectomy (LEOPARD) Thijs de Rooij et al. · Annals of Surgery Open access 3 Aug 2018 625
33 Abciximab as Adjunctive Therapy to Reperfusion in Acute ST-Segment Elevation Myocardial Infarction Giuseppe De Luca, Harry Suryapranata, Gregg W. Stone et al. · JAMA 12 Apr 2005 616
34 Overall survival in patients with BRAF-mutant melanoma receiving encorafenib plus binimetinib versus vemurafenib or encorafenib (COLUMBUS): a multicentre, open-label, randomised, phase 3 trial Reinhard Dummer, Paolo A. Ascierto, Helen J Gogas et al. · The Lancet Oncology 12 Sep 2018 589
35 Cancer risk and survival in path_MMR carriers by gene and gender up to 75 years of age: a report from the Prospective Lynch Syndrome Database Pål Møller et al. · Gut Open access 28 Jul 2017 589
36 Do We Still Hurt Newborn Babies? Sinno H. P. Simons, Monique van Dijk, Kanwaljeet J. S. Anand et al. · Archives of Pediatrics and Adolescent Medicine Nov 2003 565
37 Cancer incidence and survival in Lynch syndrome patients receiving colonoscopic and gynaecological surveillance: first report from the prospective Lynch syndrome database Pål Møller et al. · Gut Open access 9 Dec 2015 560
38 Early Extracorporeal CPR for Refractory Out-of-Hospital Cardiac Arrest Martje M. Suverein et al. · New England Journal of Medicine Open access 25 Jan 2023 558
39 Coronary Angiography after Cardiac Arrest without ST-Segment Elevation Jorrit S. Lemkes et al. · New England Journal of Medicine Open access 18 Mar 2019 548
40 Deferral vs. performance of percutaneous coronary intervention of functionally non-significant coronary stenosis: 15-year follow-up of the DEFER trial Frederik M. Zimmermann, Angela Ferrara, Nils P. Johnson et al. · European Heart Journal Open access 23 Sep 2015 545
41 Impact of Time on Improvement of Outcome After Stroke Gert Kwakkel, Boudewijn J. Kollen, Jos W. R. Twisk · Stroke Open access 24 Aug 2006 536
42 Maintenance treatment with capecitabine and bevacizumab in metastatic colorectal cancer (CAIRO3): a phase 3 randomised controlled trial of the Dutch Colorectal Cancer Group Lieke H. J. Simkens et al. · The Lancet Open access 10 Apr 2015 529
43 Early Outcome After Off-Pump Versus On-Pump Coronary Bypass Surgery Diederik van Dijk, Arno Pieter Nierich, Erik W.L. Jansen et al. · Circulation Open access 9 Oct 2001 524
44 Perinatal morbidity and mortality in early‐onset fetal growth restriction: cohort outcomes of the trial of randomized umbilical and fetal flow in Europe ( TRUFFLE ) Christoph C. Lees et al. · Ultrasound in Obstetrics and Gynecology Open access 23 Sep 2013 519
45 Left bundle branch area pacing outcomes: the multicentre European MELOS study Marek Jastrzębski, Grzegorz Kiełbasa, Óscar Cano et al. · European Heart Journal Open access 18 Aug 2022 516
46 Early versus Delayed, Provisional Eptifibatide in Acute Coronary Syndromes Robert Patrick Giugliano, Jennifer A. White, Christoph Bode et al. · New England Journal of Medicine Open access 31 Mar 2009 514
47 Prehospital initiation of tirofiban in patients with ST-elevation myocardial infarction undergoing primary angioplasty (On-TIME 2): a multicentre, double-blind, randomised controlled trial Arnoud W.J. van ’t Hof, Jurriën M. ten Berg, Ton A.A.C.M. Heestermans et al. · The Lancet Aug 2008 513
48 Metformin Associated With Lower Cancer Mortality in Type 2 Diabetes Gijs W.D. Landman, Nanne Kleefstra, Kornelis J. J. van Hateren et al. · Diabetes Care Open access 16 Nov 2009 506
49 Bivalirudin Started during Emergency Transport for Primary PCI Philippe Gabríel Steg et al. · New England Journal of Medicine Open access 30 Oct 2013 499
50 Use of a peripheral perfusion index derived from the pulse oximetry signal as a noninvasive indicator of perfusion Alexandre Pinto Lima, Peter Beelen, Jan Bakker · Critical Care Medicine Jun 2002 482

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.