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Most cited papers from Isarna Therapeutics (Germany)

What are the most cited papers from Isarna Therapeutics (Germany)?

The most cited paper from Isarna Therapeutics (Germany) is "First-in-human phase I study of ISTH0036, an antisense oligonucleotide selectively targeting transforming growth factor beta 2 (TGF-β2), in subjects with open-angle glaucoma undergoing glaucoma filtration surgery" (Norbert Pfeiffer, Bogomil Voykov, Giulia Renieri et al., 2017), with 69 citations. Next come "TGF-β1 and TGF-β2 abundance in liver diseases of mice and men" (62) and "Biological Role and Therapeutic Targeting of TGF-β3 in Glioblastoma" (60).

Showing 22 of 22 papers. Every paper is listed.

Most cited papers, sortable by citations and release date
#Paper
1 First-in-human phase I study of ISTH0036, an antisense oligonucleotide selectively targeting transforming growth factor beta 2 (TGF-β2), in subjects with open-angle glaucoma undergoing glaucoma filtration surgery Norbert Pfeiffer, Bogomil Voykov, Giulia Renieri et al. · PLoS ONE Open access 30 Nov 2017 69
2 TGF-β1 and TGF-β2 abundance in liver diseases of mice and men Anne Dropmann, Tatjana Dediulia, Katja Breitkopf‐Heinlein et al. · Oncotarget Open access 21 Jan 2016 62
3 Biological Role and Therapeutic Targeting of TGF-β3 in Glioblastoma Katharina Seystahl, Alexandros Papachristodoulou, Isabel Burghardt et al. · Molecular Cancer Therapeutics Open access 4 Apr 2017 60
4 Therapeutic Targeting of TGFβ Ligands in Glioblastoma Using Novel Antisense Oligonucleotides Reduces the Growth of Experimental Gliomas Alexandros Papachristodoulou, Manuela Silginer, Michael Weller et al. · Clinical Cancer Research Open access 17 Sep 2019 51
5 TGF-β2 silencing to target biliary-derived liver diseases Anne Dropmann et al. · Gut Open access 28 Jan 2020 43
6 An antisense oligonucleotide targeting TGF-β2 inhibits lung metastasis and induces CD86 expression in tumor-associated macrophages Isabel Huber‐Ruano, C. Raventós, Isabel Cuartas et al. · Annals of Oncology Open access 21 Jul 2017 30
7 Design and Selection of Antisense Oligonucleotides Targeting Transforming Growth Factor Beta (TGF-β) Isoform mRNAs for the Treatment of Solid Tumors Frank Jaschinski, Hanna Korhonen, Michel Janicot · Methods in molecular biology Book chapter 2015 15
8 Nanoparticle platform preferentially targeting liver sinusoidal endothelial cells induces tolerance in CD4+ T cell-mediated disease models Shu-Hung Wang et al. · Frontiers in Immunology Open access 17 Mar 2025 13
9 TGF-β isoforms in cancer: Immunohistochemical expression and Smad-pathway-activity-analysis in thirteen major tumor types with a critical appraisal of antibody specificity and immunohistochemistry assay validity Markus J. Riemenschneider, Maria Hirblinger, Arabel Vollmann‐Zwerenz et al. · Oncotarget Open access 22 Sep 2015 11
10 Potent and selective antisense oligonucleotides targeting the transforming growth factor beta (TGF-β) isoforms in advanced glaucoma: a preclinical evaluation Kathy Hasenbach, Tine Van Bergen, Evelien Vandewalle et al. · Modeling and Artificial Intelligence in Ophthalmology Open access 15 Dec 2016 7
11 A Hyperbolic Discrete Diffusion 3D RNA Inverse Folding Model for Functional RNA Design Dongyue Hou, Shuai Zhang, Mengyao Ma et al. · Journal of Chemical Information and Modeling 12 Jun 2025 5
12 Main results of the First-In Human single ascending dose phase I study of ISTH0036, an antisense oligonucleotide selectively targeting transforming growth factor beta 2 (TGF-β2) in glaucoma filtration surgery Bogomil Voykov, Hagen Thieme, Katharina Cornelia Bell et al. · Investigative Ophthalmology & Visual Science Open access 23 Jun 2017 3
13 Targeting Transforming Growth Factor beta 2 (TGF-β2) mRNA with ISTH0036 as Novel Therapeutic Intervention in Neovascular Ocular Disease Katja Wosikowski, Inge van Hoven, Jooseppi Puranen et al. · Lirias (KU Leuven) Open access May 2017 1
14 Long-term safety and efficacy of ISTH0036 – a selective TGF-β2 blocking antisense oligonucleotide in preclinical and Phase 1 clinical studies. René Rückert, Marion Ronit Munk, Katja Wosikowski et al. · Investigative Ophthalmology & Visual Science Open access 21 Jun 2021 0
15 TGF-beta 2 als therapeutische Zielstruktur bei cholestatischer Leberfibrose Anne Dropmann, Steven Dooley, Bedair Dewidar et al. · Zeitschrift für Gastroenterologie Conference paper 13 Aug 2019 0
16 Extended preclinical ocular biodistribution and pharmacodynamic profile of ISTH0036, an antisense oligonucleotide targeting transforming growth factor beta 2 (TGF-β2) for the treatment of ophthalmic diseases Katja Wosikowski, Birgit Korbmacher, Monika Krampert et al. · Investigative Ophthalmology & Visual Science Open access 13 Jul 2018 0
17 A phase I First-In Human single ascending dose study of ISTH0036, a potent and selective antisense oligonucleotide targeting transforming growth factor beta 2 (TGF-β2) for the treatment of primary open-angle glaucoma Bogomil Voykov, Katrin Lorenz, Claudia Schuart et al. · Investigative Ophthalmology & Visual Science Open access 26 Sep 2016 0
18 Anti-fibrotic and anti-inflammatory consequences of TGF-β2 silencing in biliary liver disease Anne Dropmann, Bedair Dewidar, Tatjana Dediulia et al. · Zeitschrift für Gastroenterologie 19 Dec 2016 0
19 Targeting TGF-β2 in chronic liver diseases Anne Dropmann, Hanna Korhonen, Frank Jaschinski et al. · Zeitschrift für Gastroenterologie 16 Jan 2015 0
20 TGF-β2 in Chronic Liver Disease (CLD) and Hepatocellular Carcinoma (HCC) Anne Dropmann, Albrecht Piiper, E M Alonso et al. · Zeitschrift für Gastroenterologie 13 Jan 2014 0
21 Targeting Transforming Growth Factor beta 2 (TGF-β2) Isoform with ISTH0036 - a Potent and Selective Antisense Oligonucleotide - for the Treatment of Glaucoma Kathy Hasenbach, Leonie Herrnberger, Sabrina Kuespert et al. · Investigative Ophthalmology & Visual Science 11 Jun 2015 0
22 Efficacy of ISTH0036, a Potent and Selective Antisense Oligonucleotide Targeting Transforming Growth Factor beta 2 (TGF-β2) Isoform, in Different Ocular Disease Preclinical Models Michel Janicot, Kathy Hasenbach, Tine Van Bergen et al. · Investigative Ophthalmology & Visual Science 11 Jun 2015 0

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.