| 1 |
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
Daniel J. Klionsky et al. · Autophagy
Open access2,467 authors |
2 Jan 2016 |
6,023 |
| 2 |
Mesenchymal stem cells in health and disease
Antonio Uccelli, Lorenzo Moretta, Vito Pistoia · Nature reviews. Immunology
Review |
19 Aug 2008 |
3,821 |
| 3 |
Revision and Update of the Consensus Definitions of Invasive Fungal Disease From the European Organization for Research and Treatment of Cancer and the Mycoses Study Group Education and Research Consortium
J. Peter Donnelly et al. · Clinical Infectious Diseases
Open access |
8 Oct 2019 |
2,973 |
| 4 |
Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease: a phase II study
Katarina Le Blanc, Francesco Frassoni, Lynne M. Ball et al. · The Lancet
|
May 2008 |
2,728 |
| 5 |
Analysis of shared heritability in common disorders of the brain
Verneri Anttila et al. · Science
Open access577 authors |
21 Jun 2018 |
2,056 |
| 6 |
Juvenile idiopathic arthritis
Angelo Ravelli, Alberto Martini · The Lancet
|
Mar 2007 |
2,032 |
| 7 |
Blue silver: A very sensitive colloidal Coomassie G‐250 staining for proteome analysis
Giovanni Candiano, Maurizio Bruschi, Luca Musante et al. · Electrophoresis
|
May 2004 |
1,965 |
| 8 |
X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy
Robert S. Wildin, Fred Ramsdell, Jane Peake et al. · Nature Genetics
|
2001 |
1,919 |
| 9 |
Global guideline for the diagnosis and management of mucormycosis: an initiative of the European Confederation of Medical Mycology in cooperation with the Mycoses Study Group Education and Research Consortium
Oliver A. Cornely et al. · The Lancet Infectious Diseases
Open access |
4 Nov 2019 |
1,841 |
| 10 |
Surface phenotype and antigenic specificity of human interleukin 17–producing T helper memory cells
Eva V. Acosta Rodríguez, Laura Rivino, Jens Geginat et al. · Nature Immunology
|
7 May 2007 |
1,840 |
| 11 |
Human mesenchymal stem cells modulate B-cell functions
Anna Corcione, Federica Benvenuto, Elisa Ferretti et al. · Blood
Open access |
2 Sep 2005 |
1,771 |
| 12 |
Diagnosis and management of Aspergillus diseases: executive summary of the 2017 ESCMID-ECMM-ERS guideline
Andrew J. Ullmann et al. · Clinical Microbiology and Infection
Open access |
18 Mar 2018 |
1,576 |
| 13 |
EULAR/PRINTO/PRES criteria for Henoch–Schönlein purpura, childhood polyarteritis nodosa, childhood Wegener granulomatosis and childhood Takayasu arteritis: Ankara 2008. Part II: Final classification criteria
Seza Özen et al. · Annals of the Rheumatic Diseases
Open access |
22 Apr 2010 |
1,459 |
| 14 |
TMEM16A, A Membrane Protein Associated with Calcium-Dependent Chloride Channel Activity
Antonella Caputo, Emanuela Caci, Loretta Ferrera et al. · Science
|
4 Sep 2008 |
1,284 |
| 15 |
The Human Phenotype Ontology in 2021
Sebastian Köhler et al. · Nucleic Acids Research
Open access |
16 Nov 2020 |
1,280 |
| 16 |
ESCMID guideline for the diagnosis and management of Candida diseases 2012: non-neutropenic adult patients
Oliver A. Cornely et al. · Clinical Microbiology and Infection
Open access |
25 Sep 2012 |
1,227 |
| 17 |
Hirschsprung disease, associated syndromes and genetics: a review
Jeanne Amiel et al. · Journal of Medical Genetics
Open access |
26 Oct 2007 |
1,211 |
| 18 |
A mutation in the RET proto-oncogene associated with multiple endocrine neoplasia type 2B and sporadic medullary thyroid carcinoma
Robert M.W. Hofstra, Rudy M. Landsvater, Isabella Ceccherini et al. · Nature
|
1994 |
1,158 |
| 19 |
Mesenchymal stem cells inhibit natural killer–cell proliferation, cytotoxicity, and cytokine production: role of indoleamine 2,3-dioxygenase and prostaglandin E2
Grazia Maria Spaggiari, Andrea Capobianco, Heba Abdelrazik et al. · Blood
|
19 Oct 2007 |
1,157 |
| 20 |
Neurodevelopmental outcome at 2 years of age after general anaesthesia and awake-regional anaesthesia in infancy (GAS): an international multicentre, randomised controlled trial
Andrew J Davidson et al. · The Lancet
Open access |
5 Nov 2015 |
1,136 |
| 21 |
Mapping the human genetic architecture of COVID-19
COVID-19 Host Genetics Initiative et al. · Nature
Open access3,896 authors |
8 Jul 2021 |
1,130 |
| 22 |
Consensus guidelines of ECCO/ESPGHAN on the medical management of pediatric Crohn's disease
Frank M. Ruemmele et al. · Journal of Crohn s and Colitis
Open access |
6 Jun 2014 |
1,090 |
| 23 |
Mesenchymal stem cell-natural killer cell interactions: evidence that activated NK cells are capable of killing MSCs, whereas MSCs can inhibit IL-2-induced NK-cell proliferation
Grazia Maria Spaggiari, Andrea Capobianco, Stelvio Becchetti et al. · Blood
Open access |
26 Oct 2005 |
1,060 |
| 24 |
Joint European League Against Rheumatism and European Renal Association–European Dialysis and Transplant Association (EULAR/ERA-EDTA) recommendations for the management of adult and paediatric lupus nephritis
George Βertsias et al. · Annals of the Rheumatic Diseases
Open access |
Aug 2012 |
1,030 |
| 25 |
Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)
Andrea Cossarizza et al. · European Journal of Immunology
Open access436 authors |
Oct 2019 |
1,014 |
| 26 |
The future of cystic fibrosis care: a global perspective
Scott C Bell et al. · The Lancet Respiratory Medicine
Open access |
27 Sep 2019 |
988 |
| 27 |
Human Dendritic Cells Activate Resting Natural Killer (NK) Cells and Are Recognized via the NKp30 Receptor by Activated NK Cells
Guido Ferlazzo, Ming Li Tsang, Lorenzo Moretta et al. · The Journal of Experimental Medicine
Open access |
4 Feb 2002 |
986 |
| 28 |
Polyomavirus-Associated Nephropathy in Renal Transplantation: Interdisciplinary Analyses and Recommendations
Hans Hellmuth Hirsch, Daniel C. Brennan, Cinthia Beskow Drachenberg et al. · Transplantation
|
17 May 2005 |
978 |
| 29 |
The molecular basis for Duchenne versus Becker muscular dystrophy: correlation of severity with type of deletion.
M Koenig et al. · PubMed
|
Oct 1989 |
963 |
| 30 |
Pathogen-induced human TH17 cells produce IFN-γ or IL-10 and are regulated by IL-1β
Christina E. Zielinski, Federico Mele, Dominik Aschenbrenner et al. · Nature
|
30 Mar 2012 |
935 |
| 31 |
Juvenile idiopathic arthritis
Berent J. Prakken, Salvatore Albani, Alberto Martini · The Lancet
|
Jun 2011 |
897 |
| 32 |
Identification of a novel X-linked gene responsible for Emery-Dreifuss muscular dystrophy
Silvia Bione, Elena Maestrini, Stefano B. Rivella et al. · Nature Genetics
|
Dec 1994 |
894 |
| 33 |
Identification of PVR (CD155) and Nectin-2 (CD112) as Cell Surface Ligands for the Human DNAM-1 (CD226) Activating Molecule
Cristina Bottino, Roberta Castriconi, Daniela Pende et al. · The Journal of Experimental Medicine
Open access |
11 Aug 2003 |
868 |
| 34 |
Definition, assessment and treatment of wheezing disorders in preschool children: an evidence-based approach
Paul L.P. Brand et al. · European Respiratory Journal
Open access |
30 Sep 2008 |
868 |
| 35 |
A gene deleted in Kallmann's syndrome shares homology with neural cell adhesion and axonal path-finding molecules
Brunella Franco, Silvana Guioli, Antonella Pragliola et al. · Nature
|
Oct 1991 |
853 |
| 36 |
EULAR/PReS endorsed consensus criteria for the classification of childhood vasculitides
Seza Özen, N Ruperto, M J Dillon et al. · Annals of the Rheumatic Diseases
Open access |
2 Dec 2005 |
847 |
| 37 |
SOX10 mutations in patients with Waardenburg-Hirschsprung disease
Véronique Pingault, Nadège Bondurand, Kirsten Kuhlbrodt et al. · Nature Genetics
|
Feb 1998 |
827 |
| 38 |
Incidence of severe critical events in paediatric anaesthesia (APRICOT): a prospective multicentre observational study in 261 hospitals in Europe
Walid Habre et al. · The Lancet Respiratory Medicine
Open access1,004 authors |
28 Mar 2017 |
826 |
| 39 |
Development and validation of a composite disease activity score for juvenile idiopathic arthritis
Alessandro Consolaro, Nicolino Ruperto, Anna Bazsó et al. · Arthritis Care & Research
Open access |
29 Apr 2009 |
821 |
| 40 |
Recurrent Rearrangements of Chromosome 1q21.1 and Variable Pediatric Phenotypes
Heather C. Mefford et al. · New England Journal of Medicine
Open access |
10 Sep 2008 |
816 |
| 41 |
2016 Classification Criteria for Macrophage Activation Syndrome Complicating Systemic Juvenile Idiopathic Arthritis: A European League Against Rheumatism/American College of Rheumatology/Paediatric Rheumatology International Trials Organisation Collaborative Initiative
Angelo Ravelli et al. · Arthritis & Rheumatology
Open access |
28 Aug 2015 |
782 |
| 42 |
Comparison of outcomes of unrelated bone marrow and umbilical cord blood transplants in children with acute leukemia
Vanderson Rocha · Blood
Open access |
15 May 2001 |
768 |
| 43 |
Host response to EBV infection in X-linked lymphoproliferative disease results from mutations in an SH2-domain encoding gene
Alison J. Coffey et al. · Nature Genetics
|
Oct 1998 |
764 |
| 44 |
Neurodevelopmental outcome at 5 years of age after general anaesthesia or awake-regional anaesthesia in infancy (GAS): an international, multicentre, randomised, controlled equivalence trial
Mary Ellen McCann et al. · The Lancet
Open access106 authors |
Feb 2019 |
748 |
| 45 |
A common molecular basis for three inherited kidney stone diseases
Sarah E. Lloyd, Simon H. S. Pearce, Simon E. Fisher et al. · Nature
Open access |
Feb 1996 |
730 |
| 46 |
B cell–helper neutrophils stimulate the diversification and production of immunoglobulin in the marginal zone of the spleen
Irene Puga et al. · Nature Immunology
Open access |
25 Dec 2011 |
730 |
| 47 |
Fasting Cycles Retard Growth of Tumors and Sensitize a Range of Cancer Cell Types to Chemotherapy
Changhan David Lee, Lizzia Raffaghello, Sebastian Brandhorst et al. · Science Translational Medicine
Open access |
9 Feb 2012 |
726 |
| 48 |
Two Randomized Trials of Canakinumab in Systemic Juvenile Idiopathic Arthritis
Nicolino Ruperto et al. · New England Journal of Medicine
Open access |
19 Dec 2012 |
722 |
| 49 |
Transforming growth factor β1 inhibits expression of NKp30 and NKG2D receptors: Consequences for the NK-mediated killing of dendritic cells
Roberta Castriconi, Claudia Cantoni, Mariella Della Chiesa et al. · Proceedings of the National Academy of Sciences
Open access |
19 Mar 2003 |
716 |
| 50 |
Point mutations affecting the tyrosine kinase domain of the RET proto-oncogene in Hirschsprung's disease
Giovanni Romeo, Patrizia Ronchetto, Yin Luo et al. · Nature
|
1994 |
708 |